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Background: In literature there are only a few descriptions of the typical presentation of solitary fibrous tumours (SFT) and only a few case reports showing its unusual clinical and radiological features. Methods: We retrospectively evaluated the computed tomography scans of 36 patients presenting with a histological diagnosis of SFT between 1998 and 2008. Results: We present five cases of SFT with an atypical clinical presentation and radiological features. Conclusions: SFT can occasionally present with unusual radiological features making a differential diagnosis difficult. Even thought imaging plays a fundamental role in the initial diagnostic approach, final diagnosis in only confirmed by biopsy and histology. [ABSTRACT FROM AUTHOR]

Purpose: The diagnosis of peritoneal carcinomatosis secondary to ovarian cancer is a real challenge in the cancer imaging field. In this retrospective study, we evaluate the accuracy of Single Detector Computed Tomography (SDCT), Multi Detector Computed Tomography (MDCT), and Positron Emission Tomography-Computed Tomography with F18-fluorodeoxyglucose ([¹⁸F]FDG-PET/CT) in the diagnosis of peritoneal seeding and we evaluate the possible applications of MDCT to predict the complete surgical removal of the peritoneal deposits. Methods and Materials: A total of 228 scans (91 SDCT, 89 MDCT, and 48 [¹⁸F]FDG-PET/CT) of patients with peritoneal carcinomatosis secondary to ovarian cancer proved at laparoscopy and confirmed by histopathology were retrospectively reviewed by two independent groups of Radiologists and Nuclear Medicine Physicians for the evaluation of ascites, peritoneal nodules, and omental cake signs. Results: MDCT showed 81% of true positives, SDCT 72.5%, and [¹⁸F]FDG-PET/CT 77%. False negatives were 19% for MDCT, 27.5% for SDCT, and 23% for [¹⁸F]FDG-PET/CT. Conclusion: From our results, we concluded that MDCT is the technique of choice in the diagnosis of peritoneal seeding, while [¹⁸F]FDG-PET/CT, though showing similar accuracy, remains the most accurate technique for monitoring therapeutic response and disease recurrence. MDCT could play an important role due to its ability to predict the possibility of complete surgical removal of disease thus influencing the treatment plan aimed to improve quality of life. [ABSTRACT FROM AUTHOR]

Aim: To determine the T(2) relaxation time of colorectal hepatic metastases and changes in T(2) relaxation times following chemotherapy.Materials and Methods: 42 patients with 96 hepatic colorectal metastases underwent baseline MRI. Axial T(1), T(2) and multi-echo GRASE sequences were acquired. ROIs were drawn on T(2) relaxation maps, obtained from GRASE images, encompassing metastasis and normal liver to record T(2) relaxation time values. In 11 patients with 28 metastases, MRI was repeated using same protocol at 6 weeks following chemotherapy. The median pre-treatment T(2) values of metastases and normal liver were compared using the Mann-Whitney test. The pre- and post-treatment median T(2) values of metastases were compared using the Wilcoxon-Rank test for responding (n=16) and non-responding (n=12) lesions defined by RECIST criteria. The change in T(2) values (ΔT(2)) were compared and correlated with percentage change in lesion size.Results: There was no difference in the pre-treatment median T(2) of metastases between responding (67.3±8.6) and non-responding metastases (71.4±16.5). At the end of chemotherapy, there was a decrease in the median T(2) of responding lesions (61.6±12.6) p=0.83, and increase in non-responding lesions (76.2±18.4) p=0.03, but these were not significantly different from the pre-treatment values. There was no significant difference in ΔT(2) of responding and non-responding lesions (p=0.18) and no correlation was seen between size change and ΔT(2) (coefficient=0.3).Conclusion: T(2) relaxation time does not appear to predict response of colorectal liver metastasis to chemotherapy. [ABSTRACT FROM AUTHOR]

Abstract: Aim: To determine the T 2 relaxation time of colorectal hepatic metastases and changes in T 2 relaxation times following chemotherapy. Materials and methods: 42 patients with 96 hepatic colorectal metastases underwent baseline MRI. Axial T 1, T 2 and multi-echo GRASE sequences were acquired. ROIs were drawn on T 2 relaxation maps, obtained from GRASE images, encompassing metastasis and normal liver to record T 2 relaxation time values. In 11 patients with 28 metastases, MRI was repeated using same protocol at 6 weeks following chemotherapy. The median pre-treatment T 2 values of metastases and normal liver were compared using the Mann–Whitney test. The pre- and post-treatment median T 2 values of metastases were compared using the Wilcoxon–Rank test for responding (n =16) and non-responding (n =12) lesions defined by RECIST criteria. The change in T 2 values (ΔT 2) were compared and correlated with percentage change in lesion size. Results: There was no difference in the pre-treatment median T 2 of metastases between responding (67.3±8.6) and non-responding metastases (71.4±16.5). At the end of chemotherapy, there was a decrease in the median T 2 of responding lesions (61.6±12.6) p =0.83, and increase in non-responding lesions (76.2±18.4) p =0.03, but these were not significantly different from the pre-treatment values. There was no significant difference in ΔT 2 of responding and non-responding lesions (p =0.18) and no correlation was seen between size change and ΔT 2 (coefficient=0.3). Conclusion: T 2 relaxation time does not appear to predict response of colorectal liver metastasis to chemotherapy. [Copyright &y& Elsevier]

Lymphoepithelial carcinoma is an undifferentiated nasopharyngeal carcinoma with lymphoid stroma and non-keratinizing squamous cells with distinctive clinical, epidemiological and etiological features. Conversely, lymphoepithelioma-like carcinomas (LELCs) are carcinomas that arise outside the nasopharynx but resemble a lymphoepithelioma histologically. In this case study, LELC presentation in connective tissue (left sternocleidomastoid muscle) is peculiar and unusual, but its diagnosis is supported by histological findings and clinical history, especially long disease free survival and no primary lesions in nasopharynx and lung district. We also discuss the pathogenesis, hypothesizing an embryological theory. To our knowledge, it could be the first reported case of a primary connective tissue LELC to the neck. [ABSTRACT FROM AUTHOR]