7 results on '"HIROYASU MAKUUCHI"'
Search Results
2. Evaluation of laparoscopic surgery for small bowel obstruction and factors related to outcomes.
- Author
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Hajime Kayano, Eiji Nomura, Yasuhiko Ueda, Toru Kuramoto, Takashi Machida, Shuji Uda, Masaya Mukai, Seiichiro Yamamoto, and Hiroyasu Makuuchi
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BOWEL obstructions , *LAPAROSCOPIC surgery , *SURGICAL site infections , *ENTEROSCOPY , *SURGICAL complications , *ODDS ratio - Abstract
Introduction: In recent years, laparoscopic surgery (LS) has been performed for small bowel obstruction (SBO). However, the indications and short-term and long-term outcomes of LS for SBO have not yet been established. Aim: To evaluate the usefulness of LS for SBO compared to open surgery (OS), as well as to identify risk factors for poor outcomes after LS. Material and methods: A total of 105 patients who underwent surgery for SBO were divided into OS (n = 64) and LS (n = 41) groups, and propensity score-matched analysis was used to compare the short-term and long-term outcomes of the groups. Risk factors for conversion to OS, postoperative complications, and intraoperative bowel injury in LS were also identified. Results: The incidences of surgical site infection and postoperative ileus were significantly lower in the LS group. The incidence of recurrent bowel did not differ significantly between the two groups. Prior bowel obstruction was a risk factor for conversion of LS to OS (odds ratio (OR) = 24.79, p = 0.0025). Bowel diameter was a risk factor for postoperative complications (OR = 1.50, 95% CI: 1.01-2.22) and for bowel injury (OR = 1.33, 95% CI: 1.05-1.67). Conclusions: LS for SBO had better postoperative short-term outcomes than OS. The outcomes of LS for SBO were significantly affected by prior bowel obstruction and bowel diameter. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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3. Comparison of hand-assisted laparoscopic surgery (HALS) and conventional laparotomy in patients with colorectal cancer: Final results from a single center.
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TAKAYUKI TAJIMA, MASAYA MUKAI, DAIKI YOKOYAMA, SHIGEO HIGAMI, SHUJI UDA, SAYURI HASEGAWA, EIJI NOMURA, SOTARO SADAHIRO, SEIEI YASUDA, and HIROYASU MAKUUCHI
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COLON cancer treatment , *LAPAROSCOPIC surgery , *ABDOMINAL surgery , *PROGRESSION-free survival , *SURGICAL complications - Abstract
In recent years, the use of laparoscopic surgery has been expanded to include radical curative resection. In a previous study, 212 patients with primary colorectal cancer (stages I-III) underwent radical curative resection by hand-assisted laparoscopic surgery (HALS) (n=98) or conventional laparotomy (CL) (n=114) and were compared with respect to 3-year relapse-free survival (3Y-RFS) and 3-year overall survival (3Y-OS). The study included 210/212 patients who were followed up to 5 years, including 96 patients who underwent HALS and 114 treated with CL. The two groups were matched for stage, clinical background, and postoperative management. Patient characteristics were compared and the 5Y-RFS and 5Y-OS were determined. The 5-year follow-up rate was 97.6%. In stage I-III patients, 5Y-RFS and 5Y-OS showed no significant differences between HALS and CL. The patients with stage I disease accounted for 41.7% (40/96) of the patients undergoing HALS, while stage I patients only accounted for 23.7% (27/114) of the patients undergoing CL, and the difference was significant (P=0.005). Stage II patients undergoing CL were older than those treated with HALS (P=0.017). However, there were no differences in the characteristics of stage III patients undergoing HALS or CL. In conclusion, HALS achieved a similar survival to CL in patients with stage I to III colorectal cancer. Compared with CL, HALS was performed more safely and achieved superior cosmetic results. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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4. Early rectal cancer accompanied by multiple systemic abscesses: A case report.
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TAKAYUKI TAJIMA, MASAYA MUKAI, SAYURI HASEGAWA, SOUICHIROU YAMAMOTO, EIJI NOMURA, TAKUMA TAJIRI, SOTARO SADAHIRO, SEIEI YASUDA, and HIROYASU MAKUUCHI
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COLON cancer , *PYOGENIC liver abscess , *CANCER diagnosis - Abstract
A 70-year-old man undergoing treatment for diabetes presented with a cough and pyrexia that has lasted one week. Laboratory tests demonstrated evidence of inflammation. The patient was hospitalized and antibiotic treatment was initiated, but the condition of the patient did not improve. After 2 weeks, computerized tomography scanning demonstrated the presence of multiple small nodules in the lungs and a liver abscess. The patient also developed neck pain and numbness of the upper extremities and was then transferred to Tokai University Hachioji Hospital (Tokyo, Japan). Percutaneous transhepatic drainage (PTD) of the liver abscess was performed and antibiotic treatment was initiated. Detailed examination revealed there was pyogenic spondylitis of the cervical spine, therefore abscess drainage and an anterior cervical spinal fusion were performed. Culture of each lesion resulted in Klebsiella pneumoniae growth. While continuing antibiotic treatment and rehabilitation, the gastrointestinal tract was investigated and evidence of early rectal cancer was observed. The pulmonary nodules disappeared during treatment, indicating that these were multiple lung abscesses. Four weeks following abscess drainage and anterior cervical spinal fusion, lower anterior resection was performed. The present case report describes a patient who developed multiple abscesses associated with early rectal cancer and discusses the case with reference to the literature. [ABSTRACT FROM AUTHOR]
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- 2015
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5. Expression of podoplanin and vimentin is correlated with prognosis in esophageal squamous cell carcinoma.
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MAKIKO TANAKA, HIROSHI KIJIMA, HIDEO SHIMADA, HIROYASU MAKUUCHI, SOJI OZAWA, and SADAKI INOKUCHI
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ESOPHAGEAL cancer , *SQUAMOUS cell carcinoma , *VIMENTIN , *MUCINS , *PROTEIN expression , *PROGNOSIS - Abstract
Podoplanin is a small membrane mucin, which is involved in cell migration and cancer cell invasion. However, the roles of podoplanin in esophageal squamous cell carcinoma (ESCC) are poorly understood. In the present study, 139 cases of surgically resected ESCC were analyzed and the clinicopathological significance of podoplanin membrane expression in ESCC was demonstrated. Podoplanin expression was positive in 66.2% (92/139) of ESCC samples; with weak expression in 32.4% (45/139), and strong expression in 33.8% (47/139). Membrane expression of podoplanin was significantly associated with tumor status (P=0.001), venous invasion (P=0.035) and Union for International Cancer Control stage (P=0.029). Patients who exhibited strong podoplanin expression, were shown to have a poorer prognosis [hazard ratio (HR), 3.949; 95% confidence interval (CI), 2.001-7.794]. Expression of vimentin, a mesenchymal marker, was detected in 49 cases (35.3%) and was associated with venous invasion (P=0.020). Vimentin-positive cases were also more likely to have a worse prognosis than vimentin-negative cases (HR, 2.161; 95% CI, 1.300-3.592). Podoplanin membrane expression was significantly correlated with vimentin cytoplasmic expression in ESCC (P<0.001). The present study confirmed that podoplanin and vimentin are independent predictors of mortality (HR, 3.084; 95% CI, 1.543-6.164). These results suggest that podoplanin membrane expression results in epithelial-mesenchymal transition and promotes aggressive invasion in human ESCC. [ABSTRACT FROM AUTHOR]
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- 2015
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6. Comparison of hand-assisted laparoscopic surgery and conventional laparotomy for colorectal cancer: Interim results from a single institution.
- Author
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TAKAYUKI TAJIMA, MASAYA MUKAI, MASASHI YAMAZAKI, SHIGEO HIGAMI, SOUICHIROU YAMAMOTO, SAYURI HASEGAWA, EIJI NOMURA, SOTARO SADAHIRO, SEIEI YASUDA, and HIROYASU MAKUUCHI
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COLON cancer patients , *ABDOMINAL surgery , *LAPAROSCOPIC surgery , *CANCER relapse - Abstract
The present study aimed to compare the results of hand-assisted laparoscopic surgery (HALS) and conventional laparotomy (CL) at a single institution in Japan. Of the 212 patients with stage I/II/III colorectal cancer who received a curative resection, 98 patients underwent HALS and 114 patients underwent CL. The clinical background and post-operative management did not differ between the two groups. There were no significant differences in the 3-year relapse-free and 3-year overall survival rates between the HALS and CL groups for the patients in any stage. Blood loss during surgery was 250.1 and 135.5 ml (mean and median; the same hereafter) in stage I patients receiving HALS versus 608.2 and 315.5 ml in stage I CL patients (P=0.006), while it was 277.6 and 146 ml in stage II patients receiving HALS versus 548.6 and 347 ml in stage II CL patients (P=0.004). Post-operative hospital stay was recorded at 16.8 and 15 days in stage III patients receiving HALS versus 23.1 and 21 days in stage III CL patients (P=0.001). There were no significant differences in the operating time or complications between the two groups. These results indicate that the survival rate was comparable for HALS and CL, while HALS caused less surgical stress and achieved a better cosmetic outcome. The results of the final analysis of this cohort are awaited. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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7. Laparoscopy-assisted combined resection for synchronous gastric and colorectal cancer: Report of three cases.
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Hideo Matsui, Yuichi Okamoto, Akiko Ishii, Kazuhiro Ishizu, Yasumasa Kondoh, Naoki Igarashi, Kyoji Ogoshi, and Hiroyasu Makuuchi
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LAPAROSCOPIC surgery , *ABDOMINAL cancer , *COLON cancer , *COLON surgery , *GASTRECTOMY , *CANCER patients , *CANCER treatment ,CANCER case studies - Abstract
Abstract In gastric cancer patients, the most common form of synchronous cancer is colorectal cancer. To reduce the invasiveness of the resection, a laparoscopy-assisted combined resection was performed in three patients with synchronous gastric and colorectal cancer. Although all gastric lesions were in the early stages, two colorectal lesions were advanced cases. In all cases, the laparoscopic gastric resection and reconstruction was performed first, followed by the colorectal resection. In the case of right-side colon cancer in addition to gastric cancer, it was relatively easy to perform the combined resection with lymph node dissection sharing the same ports used for the gastrectomy, although we needed an additional port. In one case, in which rectal cancer was present in addition to gastric cancer located in the upper portion of the stomach, a totally laparoscopic proximal gastrectomy was combined with a laparoscopy-assisted low anterior resection, leaving only a lower abdominal minilaparotomy wound. All patients quickly returned to normal activity without remarkable complications, with the exception of a wound infection in one patient. With a mean follow-up of 30.7 months, all patients survived without any sign of recurrence. This procedure represents a feasible option for minimally invasive treatment of synchronous gastric and colorectal cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
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