1. ADC biomarker for head and neck tumors.
- Author
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Irlanda, Pacheco-Bravo, Silvia, Hidalgo-Tobon, Kena, Zaragoza, Nancy, Reynoso-Noverón, Benito, de Celis-Alonso, and Rosa, Delgado-Hernandez
- Subjects
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TUMOR diagnosis , *BIOMARKERS , *DIFFUSION coefficients , *IMAGING systems , *SCANNING systems , *STATISTICAL correlation - Abstract
According to the World Cancer Report, by 2020, global incidence of cancer may increase by 50%, which means 15 million new cases. In 2000, malignant tumors were the cause of 12% of the almost 56 million deaths worldwide due to all causes[1-4]. 18 men and 19 women, with an average age of 53 ± 14 years with diagnosis of head and neck cancer were scanned using a 1.5-T MR imaging unit (Signa HDxt; GE Medical Systems). Echo-planar DW imaging was performed in the transverse plane before the contrast material injection. Three b values were applied: 40, 100, and 800 sec/mm2. Primary tumors and nodes were evaluated, with diameters greater than 43 ± 15mm. In our study, ADC data for b-values of 40 showed correlation for identification of malignancy in primary tumors, and in the case of nodes there is a tendency toward malignancy in sequences in which a b-value of 800 is used. [ABSTRACT FROM AUTHOR] more...
- Published
- 2014
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