1. Predictors of acute hospital mortality and length of stay in patients with new‐onset atrial fibrillation: a first‐hand experience from a medical emergency team response provider.
- Author
-
Thein, Paul M., Ong, Julia, Crozier, Tim M., Nasis, Arthur, Mirzaee, Sam, Tan, Sean X., and Junckerstorff, Ralph
- Subjects
- *
ATRIAL fibrillation diagnosis , *ATRIAL fibrillation treatment , *HEART ventricle diseases , *ATRIAL fibrillation , *CONFIDENCE intervals , *ECHOCARDIOGRAPHY , *CARDIAC contraction , *LEFT heart ventricle , *HEART failure , *LENGTH of stay in hospitals , *LONGITUDINAL method , *MULTIVARIATE analysis , *POSTOPERATIVE period , *POTASSIUM , *SINOATRIAL node , *TACHYCARDIA , *ATRIAL flutter , *SYMPTOMS , *TREATMENT effectiveness , *DISEASE duration , *HOSPITAL mortality , *ODDS ratio , *VENTRICULAR ejection fraction - Abstract
Background: Atrial fibrillation (AF) occurs frequently following cardiothoracic surgery and treatment decisions are informed by evidence‐based clinical guidelines. Outside this setting there are few data to guide clinical management. Aim: To describe the characteristics, management and outcomes of hospitalised adult patients with new‐onset AF. Methods: The medical emergency team (MET) database was utilised to identify patients who had a 'MET call' activated for tachycardia between 2015 and 2016. Patients with sinus tachycardia, pre‐existing AF/atrial flutter or other known tachyarrhythmia were excluded. Primary outcomes were length of hospital stay and in‐hospital mortality. Results: New‐onset AF was identified in 137 patients: 68 medically managed; 38 non‐cardiothoracic post‐operative; and 31 cardiothoracic post‐operative. Mean age was 74 ± 11.6 years and 72 (53%) were male. Of 79 patients who underwent echocardiography, 80% had left atrial dilatation and 14% had reduced left ventricular ejection fraction (LVEF). Mean length of stay (LOS) was 12 days and in‐hospital mortality rate was 11%. On multivariable analysis, the odds of death during acute hospitalisation was 7.4 times higher in patients with heart failure with reduced LVEF (odds ratio 7.4, 95% confidence interval (CI) 1.23–44.8, P = 0.028). Length of acute hospital stay increased by 36% if the duration of AF was longer than 48 h (beta coefficient 0.36, 95% CI −0.015 to 0.74, P = 0.059). Conclusion: Left ventricular systolic dysfunction in hospitalised patients with new‐onset AF is associated with increased all‐cause mortality whereas lower serum potassium levels are associated with an increased LOS. A prospective study is planned to compare outcomes based on in‐hospital treatment strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF