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This case study describes the use of functional assessment in combination with experimental functional analysis as methods for informing and evaluating individualized treatment in a large residential treatment setting for adolescents. The case of John, a normally developed 12-year-old male, illustrates how functional information can be used to derive a simple treatment that can be effective in modifying previously intractable and highly disruptive behavior. Challenges associated with maintenance of treatment over time are described in relation to John's follow-up status. Finally, recommendations are made about the utility of functional methodologies within residential care settings and the need for ongoing experimental evaluation testing limits of such methodologies. [ABSTRACT FROM AUTHOR]