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Purpose: To investigate the normative value of distance between the spinous processes (inter-spinous process distance, ISPD), correlations between patients' demographics and ISPD, and determine cutoff ISPD values that result in segmental lordosis in posterior cervical-thoracic arthrodesis with instrumentation.Methods: We reviewed patients with visible lower cervical and cervicothoracic spinous processes (C5-T2) on dynamic X-rays. Radiographic measurements included segmental Cobb angles (S-Cobb) and ISPD, defined as the distance between midpoints of the spinous processes. Correlations between patient demographics and ISPD were evaluated. In addition, the cutoff ISPD values that predict segmental lordosis (S-Cobb < 0°) were determined using the receiver operating characteristics (ROC) curve and linear regression model.Results: We evaluated a total of 153 films on 51 patients. The mean ISPDs in neutral position were 16.0, 20.7, 23.2, and 26.0 mm at C5/6, C6/7, C7/T1, and T1/T2, respectively There were no or only weak correlations between ISPD and age, race, height, body weight, and BMI. We observed significant difference between male and female ISPDs at C7/T1 and T1/T2 (P < 0.05). The ISPDs had moderate/strong correlations with S-Cobb at each segment (- 0.450 ≤ r ≤ - 0.705). Based on the ROC curves, the following cutoff values of ISPD provided 100% positive predictive value for segmental lordosis: < 10 mm at C5-6; < 15 mm at each level from C6 to T2.Conclusion: ISPD is a simple and useful parameter that correlates with the segmental Cobb angle. During posterior cervical deformity surgery, surgeons can intraoperatively predict adequate segmental lordosis by utilizing the vertebral level specific cutoff values of ISPD. These slides can be retrieved under Electronic Supplementary Material. [ABSTRACT FROM AUTHOR]

BACKGROUND CONTEXT Postoperative shoulder height imbalance is a common complication following adolescent idiopathic scoliosis (AIS) surgery. It is thought that a more cephalad upper instrumented vertebra (UIV) decreases the risk of shoulder imbalance in Lenke type 1 curves, however this has not been proven. PURPOSE To test the hypothesis that "over-correction" of the main thoracic curve without control of the proximal curve increases the risk for shoulder imbalance in Lenke type 1 AIS. STUDY DESIGN/SETTING Clinical photo and x-ray review of patients with Lenke 1 Main Thoracic AIS curves. PATIENT SAMPLE Surgically-treated patients with Lenke type 1 AIS were reviewed from a large multicenter database. OUTCOME MEASURES Postoperative shoulder height balance on clinical photos and PA radiographs. METHODS A total of 13 surgeons reviewed preop and 5-year postop clinical photos and PA radiographs of patients from a large multicenter database with Lenke type 1 AIS curves who were corrected with pedicle screw or rod constructs. Predictors of postop shoulder imbalance were identified by univariate analysis; multivariate analysis was done using the classification and regression tree (CART) method to identify independent drivers of shoulder imbalance. RESULTS A total of 145 patients were reviewed. The UIV was T3-T5 in 87% of patients, with 8.9% instrumented up to T1 or T2. 52 (36%) had shoulder imbalance at 5 years. On CART analysis: when the proximal thoracic (PT) Cobb angle was corrected more than 52%, 80% of the patients had balanced shoulders. Similarly, when the PT curve was corrected less than 52% and the main thoracic (MT) curve was corrected less than 54%, 87% were balanced. However, when the PT curve was corrected less than 52%, and the MT curve was corrected more than 54%, only 41% of patients had balanced shoulders (p=0.05). This relationship was maintained regardless of the UIV level. CONCLUSIONS In Lenke type 1 AIS curves, "over-correction" of the main thoracic curve (>54%) with simultaneous "under-correction" (<52%) of the upper thoracic curve resulted in shoulder height imbalance in 59% of patients, regardless of the UIV. This suggests the PT curve must be carefully considered in order to optimize shoulder balance, especially when larger correction of the MT curve is performed. [ABSTRACT FROM AUTHOR]

Study Design: Retrospective cross-sectional cohort.Objective: To investigate the prevalence and predictive factors of concurrent cervical spinal cord compression (CSCC) in patients with adult spinal deformity (ASD).Summary Of Background Data: In patients with ASD undergoing major thoracolumbar realignment surgery, concurrent CSCC potentially increases the risk of progression of myelopathy or cervical cord injury due to various perioperative factors including poor intraoperative neck positioning and hypotension. However, the prevalence of CSCC in ASD patients has not been previously studied.Methods: This study included ASD patients who were indicated for major thoracolumbar corrective surgery (>5 levels). The presence of CSCC was determined using the modified Cord Compression Index (Grades 0-3) based on the cervical magnetic resonance imaging (MRI). Significant CSCC was defined as Grade>2, and the distribution of compression level as well as the number of Grade>2 segments were investigated in each patient. A multivariate regression analysis was performed to identify the predictors of CSCC with variables being the patients' characteristics including radiographic sagittal alignment parameters.Results: Of 121 patients with ASD, 41 patients (33.8%) demonstrated significant CSCC on MRI. Intramedullary T2 hyper-intensity (myelomalacia) was present in eight patients (6.6%). Thirty-five of 41 patients were asymptomatic or with myelopathy that is difficult to detect. Significant CSCC was most commonly observed at C4/5 level. Four patients (3.3%) underwent cervical decompression and fusion prior to thoracolumbar reconstruction. Multivariate regression analysis revealed old age, increased body mass index (BMI), and PI-LL mismatch independently predicted the CSCC grade.Conclusion: The prevalence of concurrent significant cervical cord compression in patients with ASD is relatively high at 33.8%. Preoperative evaluation of cervical MRI and examinations for signs/symptoms of myelopathy are essential for patients with (1) older age, (2) increased BMI, and (3) high PI-LL mismatch to avoid progressive myelopathy or cord injury during ASD surgery.Level Of Evidence: 4. [ABSTRACT FROM AUTHOR]

Objective. To report a nationwide survey of the endoscopic spine surgeons across Thailand. Furthermore, the survey will be focused on the perspective of experience, learning curve, motivations, and obstacles at the beginning of their practices. Materials and Methods. The online survey consisting of 16 items was distributed to spine surgeons who are performing endoscopic spine surgery in Thailand via the Google forms web-based questionnaire to investigate participants' demographics, backgrounds, experience in endoscopic spine surgery, motivations, obstacles, and future perspectives. The data was recorded from January 7, 2020 to January 21, 2022. Descriptive statistics were used for analysis. Results. A total of 42 surveys were submitted by 6 neurosurgeons (14.3%) and 36 orthopedic surgeons (85.7%). From the surgeons' perspective, the average number of cases that should be performed until one feels confident, consistently good outcomes, and has minimal complications was 27.44 ± 32.46 cases. For surgeons who starting the endoscopic spine practice, at least 3 workshop participation is needed. Personal interest (39 selected responses) and trending marketing or business purpose (25 selected responses) were the primary motivators for endoscopic spine surgery implementation. Lack of support (18 selected responses) and afraid of complications (16 selected responses) were pertinent obstacles to endoscopic spine surgery implementation. Conclusions. The trend of endoscopic spine surgery has continued to grow in Thailand, shown by the rate of implementation of endoscopic spine surgery reported by Thai spine surgeons. The number of appropriate cases until one feels confident was around 28 cases. The primary motivator and obstacles were personal interest and lack of support. [ABSTRACT FROM AUTHOR]

Background Context: Few studies have described reciprocal changes of pathologic compensatory mechanisms in the setting of spinopelvic fixation using full-body radiograph.Purpose: To elucidate how sagittal alignment of unfused spinal segments and lower extremities change reciprocally following complex thoracolumbar realignment surgery including fusion to the sacrum in adult spinal deformity.Study Design: Retrospective cohort.Patient Sample: Thirty-four patients who underwent fusion from lower thoracic to the sacrum/pelvis and 49 patients with fusion from upper thoracic to the sacrum/pelvis.Outcome Measures: The postoperative sagittal alignment change, and the correlation between the instrumented spinopelvic alignment change and reciprocal changes in unfused spinal segments/lower extremities.Materials/methods: This study included 34 patients who underwent fusion from lower thoracic to the sacrum/pelvis (LT-P group) and 49 patients with fusion from upper thoracic to the sacrum/pelvis (UT-P group). The postoperative sagittal alignment changes were evaluated after subdividing the two groups according to T1 pelvic angle (TPA) (aligned group: TPA<20 and malaligned group: TPA>20). The correlation between the instrumented spinopelvic alignment change (ΔTPA and ΔLL), reciprocal changes in unfused spinal segments and lower extremities, and the cranial sagittal vertical axis-hip/ankle change (ΔCrSVA-Hip/Ankle) were also analyzed.Results: At the baseline in both LT-P and UT-P groups, the patients in the malaligned subgroups showed greater C2-7 lordosis (C2-7L), sacrofemoral angle (SFA), and knee flexion angle (KA) than those in the aligned subgroups. At average 7.1 months postoperatively, these compensatory mechanisms were restored in accordance with instrumented TPA/LL change, especially in the UT-P group. The mid-thoracic alignment changed significantly kyphotic in the LT-P group. ΔTPA and ΔLL linearly correlated with ΔC2-7L, ΔKA, and ΔAA in the malaligned patients. The multivariate regression analysis revealed that change in lower extremity parameters (ΔSFA, ΔKA, and ΔAA) independently impacted ΔCrSVA-Hip/Ankle.Conclusion: Adequate thoracolumbar realignment surgery results in restoration of the pathologic compensatory mechanisms in the unfused spinal segments and lower extremities, especially in patients fused from upper thoracic spine. A preoperative clinical evaluation of the lower limb joints, as well as a full-body radiographic evaluation, is paramount to achieve optimal global sagittal balance in thoracolumbar realignment surgery. [ABSTRACT FROM AUTHOR]

Study Design: Retrospective cohort.Objective: This radiographic analysis using a full-body x-ray evaluated the ways in which the sagittal profiles of the unfused spinal segments, pelvic, and lower extremities spontaneously change after adolescent idiopathic scoliosis (AIS) surgery with segmental pedicle screw constructs.Summary Of Background Data: Reciprocal lordotic changes in unfused spinal segments after corrective surgery for AIS have been reported. However, a full-body analysis has not been studied.Methods: The sagittal profiles of 51 (age ≤18) patients with AIS undergoing corrective surgery with segmental pedicle screw constructs were investigated. Patients were divided into two groups: group T; selective thoracic fusion and group L; fusion to the low lumbar spine. They were further subcategorized according to preoperative thoracic kyphosis (TK: T5-12): hypokyphotic (TK <20°) and normohyperkyphotic (TK >20°) groups. The postoperative change in the sagittal parameters and the correlation between the instrumented thoracic alignment change (ΔT2-12) and reciprocal changes of unfused segments were analyzed.Results: At baseline, the entire cohort had a relatively hypokyphotic thoracic spine (TK: 25.5° ± 13.7°), low T1 slope (13.6° ± 7.7°), and kyphotic cervical spine (C2-7 lordosis: 7.7° ± 13.1°). The lower extremities were in neutral alignment overall. Postoperatively, the cervical alignment changed significantly lordotic (average -13.4° increased lordosis) after the adequate preservation of TK (average 17.8° increased kyphosis) in the hypokyphotic group T. Linear correlations were observed between ΔT2-12 and spontaneous reciprocal changes in C2-7 lordosis, lumbar lordosis, and knee flexion angle in group T.Conclusion: The sagittal profiles of patients with AIS can significantly change after adequate restoration of TK which averaged 17.8°, particularly in the cervical spine. Lordotic reciprocal change in the cervical spine as well as increase in lumbar lordosis can occur in a linear correlation after adequate restoration of TK. There were no significant changes that occurred in the pelvis or lower extremities after AIS corrective surgery.Level Of Evidence: 4. [ABSTRACT FROM AUTHOR]

Study Design: Retrospective review of a prospectively collected multicenter database.Objective: To assess how "overcorrection" of the main thoracic curve without control of the proximal curve increases the risk for shoulder imbalance in Lenke type 1 Adolescent Idiopathic Scoliosis (AIS).Summary Of Background Data: Postop shoulder imbalance is a common complication following AIS surgery. It is thought that a more cephalad upper-instrumented vertebra (UIV) decreases the risk of shoulder imbalance in Lenke type 1 and 2 curves; however, this has not been proven.Methods: Thirteen surgeons reviewed preop and 5-year postop clinical photos and PA radiographs of patients from a large multicenter database with Lenke type 1 and 2 AIS curves who were corrected with pedicle screw/rod constructs. Predictors of postop shoulder imbalance were identified by univariate analysis; multivariate analysis was done using the classification and regression tree method to identify independent drivers of shoulder imbalance.Results: One hundred forty-five patients were reviewed. The UIV was T3-T5 in 87% of patients, with 8.9% instrumented up to T1 or T2. Fifty-two (36%) had shoulder imbalance at 5 years. On classification and regression tree analysis when the proximal thoracic (PT) Cobb angle was corrected more than 52%, 80% of the patients had balanced shoulders. Similarly, when the PT curve was corrected less than 52% and the main thoracic (MT) curve was corrected less than 54%, 87% were balanced. However, when the PT curve was corrected less than 52%, and the MT curve was corrected more than 54%, only 41% of patients had balanced shoulders (P = 0.05). This relationship was maintained regardless of the UIV level.Conclusion: In Lenke type 1 and 2 AIS curves, significant correction of the main thoracic curve (>54%) with simultaneous "under-correction" (<52%) of the upper thoracic curve resulted in shoulder height imbalance in 59% of patients, regardless of the UIV. This suggests the PT curve must be carefully scrutinized in order to optimize shoulder balance, especially when larger correction of the MT curve is performed.Level Of Evidence: 2. [ABSTRACT FROM AUTHOR]