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1. Short-term acute bright light exposure induces a prolonged anxiogenic effect in mice via a retinal ipRGCCeA circuit.

Author

Ge Wang, Yun-Feng Liu, Zhe Yang, Chen-Xi Yu, Qiuping Tong, Yu-Long Tang, Yu-Qi Shao, Li-Qin Wang, Xun Xu, Hong Cao, Yu-Qiu Zhang, Yong-Mei Zhong, Shi-Jun Weng, and Xiong-Li Yang

Subjects
*SUPRACHIASMATIC nucleus, *PHOTORECEPTORS, *MICE, *RETINAL ganglion cells, *PUPILLARY reflex, *BODY temperature regulation, *NEUTRAL density filters, *LATERAL geniculate body, *DOPAMINE receptors
Abstract

The article discusses a study on how short-term acute bright light exposure can lead to prolonged anxiety-related behavior in mice. The study, conducted by a team of researchers, shows that melanopsin-based intrinsically photosensitive retinal ganglion cells (ipRGC) activities in the brain,play a key role in this effect. The findings reveal a non-image forming visual circuit specifically designed for "the delayed" extinction of anxiety against potential threats.

Published
2023
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