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2 results on '"Rāviņa, I."'

1. Synthesis of Novel 4-Aminotetrahydropyrrolo[1,2- a]quinazoline Derivatives.

Author

Zicāne, D., Tetere, Z., Rāviņa, I., and Turks, M.

Subjects
*CHEMICAL synthesis, *QUINAZOLINE, *CHEMICAL derivatives, *CHEMOSELECTIVITY, *AMIDES, *CYCLOHEXENE
Abstract

Decarboxylation of substituted monohydrazides of 6-arylcyclohex-3-ene-1,1-dicarboxylic acids proceeds stereospecifically and leads to 1,6- cis-disubstituted cyclohex-3-enes. Due to the presence of the anthranilic acid moiety these decarboxylated hydrazides undergo formation of pyrrolo[1,2- a]quina-zolines when treated with 2-oxoglutaric acid. The present paper describes the first example of chemoselective synthesis of amide-linked conjugates between the cyclohexene moiety and tetrahydro-pyrrolo[1,2- a]quinazolines. [ABSTRACT FROM AUTHOR]

Published
2013
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2. Synthesis and antioxidant activity of new analogs of Quin-C1.

Author

Mieriņa, I., Tetere, Z., Zicāne, D., Rāviņa, I., Turks, M., and Jure, M.

Subjects
*ANTIOXIDANTS, *CHEMICAL synthesis, *CROTONALDEHYDE, *AMINOBENZOIC acids, *QUINAZOLINE, *CONDENSATION
Abstract

New derivatives of 4-oxo-1,2,3,4-tetrahydroquinazoline, analogs of Quin-C1, have been synthesized by the condensation of aroyl- and heteroaroylhydrazides of anthranilic acid with cinnamic, crotonic, and 4-hydroxy-3-methoxybenzoic aldehydes. The antioxidant activity of the obtained compounds has been determined. [ABSTRACT FROM AUTHOR]

Published
2013
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