1. Migraine in women with chronic pelvic pain with and without endometriosis
- Author
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Karp, Barbara Illowsky, Sinaii, Ninet, Nieman, Lynnette K., Silberstein, Stephen D., and Stratton, Pamela
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MIGRAINE , *PELVIC pain , *DISEASES in women , *ENDOMETRIOSIS , *LAPAROSCOPIC surgery , *DISEASE prevalence , *QUALITY of life , *PATHOLOGICAL physiology , *HEADACHE , *ESTROGEN antagonists , *CHRONIC diseases , *CLINICAL trials , *COMBINED modality therapy , *COMPARATIVE studies , *LAPAROSCOPY , *LONGITUDINAL method , *RESEARCH methodology , *MEDICAL cooperation , *PLACEBOS , *RESEARCH , *EVALUATION research , *THERAPEUTICS - Abstract
Objective: To examine the prevalence of migraine in women with chronic pelvic pain with and without endometriosis.Design: Prospective study of headache, pelvic pain, and quality of life before laparoscopic surgery for pelvic pain. Endometriosis was diagnosed pathologically. Headaches were classified as migraine or non-migraine using International Headache Society criteria.Setting: Clinical research hospital.Patient(s): 108 women in a clinical trial for chronic pelvic pain (NCT00001848).Intervention(s): Laparoscopy to diagnose endometriosis, assessment by neurologist to assess headaches.Main Outcome Measure(s): Prevalence of migraine and other headaches in women with chronic pelvic pain with or without endometriosis. Headache frequency, severity and relationship to pelvic pain and endometriosis.Result(s): Lifetime prevalence of definite or possible migraine was 67% of women with chronic pelvic pain. An additional 8% met criteria for possible migraine. Migraine was no more likely in women with endometriosis than those without. Women with the most severe headaches had a lower quality of life compared with those with pelvic pain alone.Conclusion(s): Migraine headache is common in women with chronic pelvic pain, regardless of endometriosis, and contributes to disability in those with both conditions. The strong association suggests a common pathophysiology. [ABSTRACT FROM AUTHOR]- Published
- 2011
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