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Objective: The aim of the present study is to determine the prevalence of abnormal endometrial histology, premalignancy, and malignancy in women diagnosed with epithelial ovarian tumors and tumor-like conditions (PCOS, endometriosis, stromal hyperplasia, and stromal hyperthecosis). Materials and methods: Endometrial and ovarian specimens of 71 patients with epithelial ovarian tumors were retrospectively selected, and the histopathology was analyzed. Moreover, 79% had serous tumors, 15.4% had mucinous tumors, and 5.6% other tumors (fibrothecoma, cystadenofibroma). Ovarian histopathology was compared with the concurrent endometrial pathology. Results: Among the samples analyzed, 41% had abnormal endometrial histology, of which 29% is polypoidal endometrium and 12% is disordered proliferation, both of which represent hyperestrogenic state. Conclusion: Abnormal endometrial histology due to stromal steroidogenesis and its biological action on endometrium is well-known; hence, endometrial evaluation is mandatory for planning treatment and understanding the disease process of epithelial ovarian tumors. [ABSTRACT FROM AUTHOR]

Purpose The purpose of this paper is to determine the optimum level of geometrical parameters such as helix angle, nose radius, rake angle and machining parameters such as cutting speed, feed rate and depth of cut to arrive minimum surface roughness and tool wear during end milling of Al 356/SiC metal matrix composites (MMCs) using high speed steel end mill cutter.Design/methodology/approach L27 Taguchi orthogonal design with six factors and three levels is employed for conducting experiments. Analysis of variance (ANOVA) is carried out using Minitab16 software to find the influence of each input parameter on output performance measure. Grey-fuzzy logic multi optimisation algorithm is used to find the optimum level of the input parameters for minimum surface roughness and tool wear simultaneously.Findings It is found that optimal combination of helix angle 40°, nose radius 0.8 mm, rake angle 12°, cutting speed 90 m/min, feed rate 0.04 mm/rev and depth of cut 1.5 mm have generated minimum surface roughness of 0.4063 µm and tool wear of 0.0375 mm. From ANOVA analysis, it is found that cutting speed influence is more on output performance followed by helix angle and rake angle compared with other machining and geometrical parameters.Originality/value The influence of tool geometry during end milling of MMC using Grey-fuzzy logic algorithm has not been explored previously. [ABSTRACT FROM AUTHOR]

Abstract  A new mannich base 1-[(2,5-dioxopyrrolidin-1-yl)(phenyl)methyl] thiourea formed by the direct condensation of thiourea, succinimide and benzaldehyde has been synthesized. The structure of this mannich base has been elucidated on the basis of micro elemental analysis, IR, 1H NMR, 13C NMR, Mass and UV–Visible Techniques. The crystal structure of the title compound C12 H13 N3 O2 S was determined. It crystallizes in the monoclinic system, space group P21/c with a = 10.8234 (7) Å, b = 6.0355 (5) Å, c = 19.3692 (14) Å, β = 100.540(3)°, Z = 4 and V = 1243.94 (16) Å3. The structure was solved by the full-matrix least squares on F 2 and had a refined R value of 0.0465 for 1,964 observed reflections. The crystal structure is stabilized by strong intramolecular C–H···O, C–H···S interactions and inter molecular N–H···O and S···S interactions. Graphical Abstract  This paper describes the spectroscopic and crystallographic studies of the title compound which is essential in ascertaining the structure of this new compound. [ABSTRACT FROM AUTHOR]

Emphasizes the need for the basic conceptual clarity regarding the measures of agricultural research effort. Returns to investments in research; Determinants of research investment; Discussion on the national agricultural research expenditure; Econometric specifications; Research policy statements.

Drug-induced lung diseases are a frequent cause of morbidity. Diffuse pulmonary haemorrhage is an uncommon complication of drug therapy, and is a potentially life-threatening situation. We report the high-resolution CT and clinical findings of a 32-year-old man with diffuse pulmonary haemorrhage induced by ketorolac tromethamine. [ABSTRACT FROM AUTHOR]