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Introduction: Metastases to the female genital tract from extragenital primary tumors are unusual. We report a rare case of uterine cervix metastasis from colon adenocarcinoma and discuss diagnostic and therapeutic issues.Case Report: We report a case of a 38-year-old North African Caucasian woman treated for a non-metastatic colon adenocarcinoma. She had a sigmoidectomy and incomplete adjuvant chemotherapy. Six months later, she consulted with vaginal bleeding caused by a cervical tumor, which was confirmed to be metastatic disease, and the patient underwent decompressive and hemostatic radiotherapy.Conclusion: Uterine cervix metastasis from primary colon adenocarcinoma is rare. The resection remains the standard protocol for the local treatment of resectable metastatic disease. Otherwise, systemic therapy is the preferable option. [ABSTRACT FROM AUTHOR]

In this paper the directional hemispherical reflectivity and transmissivity of one-dimensional, randomly rough, dielectric surfaces are determined by the use of the integral method. This method is derived from electromagnetic theory without any restrictive hypotheses. Since this exact approach is computationally very intensive, a geometric optics approximation method is also developed. Curves displaying radiative properties versus the correlation length for a constant mean square deviation of the surface from flatness are presented. In this respect, the influence on the validity of the approximate method of multiple scattering, the shadowing effect and the real index of refraction of the dielectric have been investigated. Transverse electric and transverse magnetic polarized incident plane waves are considered. For the latter, our interest is focused on the influence of roughness on the reflected and transmitted intensities for an angle of incidence close to the Brewster angle. [ABSTRACT FROM AUTHOR]

The decreased affinity to β-lactams in Haemophilus influenzae is usually caused by specific alterations in penicillin-binding protein 3 due to varieties of substitutions in ftsI gene. This study aimed to characterize the polymorphism of ftsI gene in 19 H. influenzae strains, isolated between 2014 and 2016 (different resistance phenotypes to β-lactams (n = 9) and susceptible strains (n = 10) used for comparative purposes). All strains were characterized for capsular type by PCR and agglutination tests and for β-lactam resistance by amplification and sequencing of ftsI. Biotyping and clonality were performed by API-NH and pulsed-field gel electrophoresis, respectively. Four strains were β-lactamase-negative ampicillin-resistant and five were β-lactamase-positive clavulanic-acid-resistant. One strain from each group was resistant to cefotaxime. Our isolates belonged mainly to biotype IV and I and were non-typeable and genetically unrelated. According to mutation profiles of their ftsI , strains were classified as group I (n = 3), group II (n = 4), group–III–like (n = 1) and group III (n = 1). All group II strains were further classified as subgroup IIb, except for one strain, which harboured a new mutation (N422I). Ampicillin MICs of β-lactamase-negative ampicillin-resistant strains were 6 to 12 times the MICs of susceptible strains. Only bla TEM-1 was detected in β-lactamase-positive clavulanic-acid-resistant strains, and was responsible for high MICs for ampicillin (>256 mg/L), whatever the ftsI mutational resistance group. The emergence of cefotaxime-resistant isolates in our country is a matter of concern and requires strict surveillance and rationalization of antibiotic use to preserve these molecules. [ABSTRACT FROM AUTHOR]

Bacillus cereus is a ubiquitous spore-forming gram-positive bacterium. The antibacterial molecules or bacteriocins provide an ecological advantage to B. cereus and promote its proliferation in the bacterial communities and food contamination. The goal of the present work was to detect and identify the antimicrobial activity potential of 114 B. cereus food strains. It aimed at accessing the ecological status of B. cereus variants and characterizing the bacteriocins. An inhibitory activity was detected in 61.4% of the collection. Three selected isolates were found to be bacteriocin (cerein) producers and were identified as B. cereus by 16S rRNA gene sequencing. The cerein activities were inhibited by at least one protease treatment. They were stable within a wide range of pH, sustained heat treatments (up to 96°C for 30 min) and treatment with organic solvents and detergents. These cereins showed bactericidal and bacteriolytic effects. They belonged to class II of bacteriocins. The three cereins were produced at the early stationary phase and remained stable until 50 h of cultivation. The preparation trough SDS PAGE gave an inhibitory zone with an apparent molecular weight of about 10 kDa to the three cereins. The three selected bacteriocins produced by B. cereus dairy strains deserve further research of their potential in pathogen control. Bacteriocin production may play a key role in the ubiquitous distribution of B. cereus and his persistency in dairy products. [ABSTRACT FROM AUTHOR]