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Summary: Background and Aims: Diminished quality of life has been well characterized in patients with autoimmune hepatitis (AIH); however, the full spectrum of unmet needs is unclear. We hypothesized that there is a high burden of health‐related unmet needs in patients with AIH, and this burden differs by socioeconomic status (SES). Methods: Members of the Autoimmune Hepatitis Association were invited online and by email to complete a modified version of the Systemic Lupus Erythematosus Patient Needs Questionnaire. Demographic and clinical data were also captured. Low SES was defined as annual household income <30 k, education level below high school, or moderate–high concern for transportation, food or housing. Multivariable logistic regression assessed the association between unmet health‐related needs and SES. Results: There were 433 participants; 89.8% identified as women, 16.2% lived outside the US, and 25.6% were classified as low SES. Over 70% of respondents reported at least one moderate–high need in the health‐related unmet need domains. In multivariable logistic regression, patients in the low‐SES group reported significantly higher odds of unmet needs compared to the moderate–high‐SES group: for adequate information about side effects (OR 1.64, 95% CI 1.06–2.53, p = 0.026), opportunity to speak with others with AIH (OR 2.34, 95% CI 1.50–3.66, p < 0.001), healthcare professionals acknowledging patient emotions (OR 2.41, 95% CI 1.56–3.74, p < 0.001) and being taken seriously by medical providers (OR 2.09, 95% CI 1.34–3.28, p = 0.001). Conclusion: There is a high burden of health‐related unmet needs in all patients with AIH that is exacerbated by low SES. [ABSTRACT FROM AUTHOR]

Fresh market vegetables are an essential component of the human diet. Maximizing yield is critical, and to achieve this goal, fields must be weed-free when vegetable crops are planted. Historically, removing emerged weeds just before planting has been accomplished using the herbicide glyphosate. However, recent research has indicated that glyphosate applied to sandy, low-organic-matter soils just before transplanting vegetables can be injurious. Two field experiments investigated 1) the response of transplanted squash to the residual activity of glyphosate, and 2) the effects of implementing tillage, irrigation, or extending the plant-back interval after application and before planting to mitigate injury from glyphosate. Glyphosate applied at 1.3, 2.5, or 3.8 kg ae/ha 1 day before transplanting injured squash 13%, 29%, and 53%, respectively; extending the interval between application and planting to 7 days reduced injury to 1%, 11%, and 28% at the same rates. An interaction between application rate and planting interval was also observed on squash plant widths and biomass, as well as early-season and total marketable fruit numbers and weights. Total marketable fruit number was reduced 29% and 52% by glyphosate at 2.5 or 3.8 kg ae/ha, respectively, and a reduction in fruit production of 36%, 28%, and 23% was observed when glyphosate was applied 1, 4, or 7 days before transplanting, respectively. In a separate study, light tillage (5 cm deep) was the most effective cultural practice evaluated because it eliminated damage by glyphosate. Overhead irrigation of 0.6 cm was not beneficial in mitigating injury by glyphosate. Recommendations from this research will help vegetable growers avoid injury from the residual activity of glyphosate through a FIFRA 2(ee) recommendation label. [ABSTRACT FROM AUTHOR]

Background/Aims: Feedback plays a pivotal role in learning, but traditional written feedback often lack engagement and specificity, hindering learners' ability to effectively apply feedback. In midwifery education, the need for innovative feedback delivery mechanisms is pronounced. The aim of this study was to evaluate the integration of digital health technologies in feedback delivery in a midwifery programme. Methods: A novel communication strategy was implemented in a midwifery programme in northwest England, where the benefits, challenges and future implications of leveraging digital health technologies for assessment feedback were assessed. Results: Preferences were mixed, with 45.1% of learners favouring written feedback. Verbal feedback was perceived as more personal and motivating, and valued for its nuance, tone and ability to clarify complex points, although written feedback provided clearer, detailed information for future reference. Less experienced markers struggled with verbal feedback, while more experienced markers appreciated the quicker, more refreshing process. All markers found feedback templates helpful for ensuring equitable feedback. Conclusions: This study scrutinised the significance of rethinking feedback delivery in midwifery education and indicates that digital health technologies present promising opportunities for reshaping the feedback landscape. Implications for practice: Developing student confidence and competence in digital literacy remains a significant challenge. Higher education institutions can collaborate with healthcare providers to offer training in digital health technologies, helping midwives adapt to modern clinical environments. [ABSTRACT FROM AUTHOR]

Background: Juvenile idiopathic arthritis (JIA) is common in pediatric rheumatology. Despite treatment, many patients experience persistent disease activity. Joint hypermobility (JH), defined by an excessive range of motion across multiple joints, is prevalent in children and adolescents and may influence disease outcomes in JIA. Objective: This study examines the impact of JH on symptoms in youth and young adults with JIA. Methods: Data were obtained from the PR-COIN network and included patients under 21 years old with a diagnosis of JIA. Patients with JIA and JH were matched with those having JIA-only based on age, sex assigned at birth, JIA subtype, and medication exposure. Clinical data, including disease activity measures, patient well-being, and pain ratings, were collected at baseline and follow-up visits. Results: The sample included 420 patients with JIA + JH and 2100 with JIA only. The JIA + JH group exhibited higher disease activity at baseline, more active arthritis joints, elevated physician global assessment of disease activity scores, and worse patient-reported well-being. These differences persisted over time. The JIA + JH group had a 19–20% greater likelihood of maintaining high disease activity scores and worsening over subsequent visits, indicating a significant impact of JH on disease progression. Conclusion: JH in youth with JIA is associated with higher and persistent disease activity, suggesting that JH significantly contributes to the disease burden in patients with JIA and should be considered in treatment strategies. Future research should further explore the mechanisms by which JH influences disease activity and investigate comprehensive management approaches to improve outcomes for this population. Key Points • Children with JIA and joint hypermobility (JH) exhibit significantly higher disease activity at baseline compared to those with JIA only, including more active arthritis joints and elevated physician global assessment scores. • The presence of JH in JIA patients is associated with poorer patient-reported well-being and higher overall disease activity scores, which persist over time despite treatment. • JIA + JH patients have a 19–20% greater likelihood of maintaining high disease activity and worsening over subsequent visits, indicating a significant impact of JH on disease progression. • The study suggests that JH should be considered an important clinical factor in the management of JIA, with targeted interventions needed to address the increased disease activity and improve overall patient outcomes. [ABSTRACT FROM AUTHOR]

Many women experiencing homelessness and intimate partner violence (IPV) often do not use formal support services due to barriers such as finances, inaccessibility, controlling partners, and stigma. The current literature lacks studies that examine the formal service experiences of women who have undergone both homelessness and IPV. Therefore, the current study used a qualitative-dominant design and explored the formal service needs of these women, barriers and facilitating factors associated with accessing services, and how the women's identities affected their experiences with formal services. Interviews with 10 women were conducted, and a reflexive thematic analysis was conducted using a critical feminist and intersectionality lens. The most common factors that led to homelessness were conflict and precarious circumstances leading to housing instability. Common barriers were systemic, psychological, dismissal, minimization, and financial barriers. The most common needs were health, finances, and basic necessities. The most common facilitating factors were support networks and resilience, growth, and proactivity. The social positionings most commonly affecting their experiences were class and race/ethnicity. These findings highlighted the voices of marginalized women and can be used to implement positive change in formal services that cater to this subgroup of women. [ABSTRACT FROM AUTHOR]

Black women embody self-determination and strength to overcome intersecting racism and sexism. This notion of strength has been operationalized as the Strong Black Woman (SBW) schema, and growing research on this schema has been mixed. Quantitative findings have largely connected this schema to negative health outcomes whereas qualitative work has revealed positive benefits of this schema. To further understand the complexity of this schema, we drew from a positive psychology framework to examine how this schema related to resilience, self-efficacy, and flourishing. Correlation and linear regression analyses were performed with data from 178 young adult Black women (Mage = 20.48, SD = 1.38) who were recruited from a Historically Black College in the Southeastern region of the United States. Regression findings revealed that some characteristics (e.g., obligation to manifest strength, intense motivation to succeed) were positively associated with resilience, self-efficacy, and flourishing whereas others (e.g., extraordinary caregiving, emotional suppression) were negatively associated with these outcomes. Our results further complicate the role of the SBW schema in the lives of Black women and support the need for continued research on this topic. Public Health Statement: Many Black women are socialized to be strong and tenacious in the face of hardship. This study examined if being strong contributed to positive outcomes, like resilience, self-efficacy, and flourishing in a sample of college-aged Black women. We found that although some dimensions of strength were positively associated with resilience, self-efficacy, and flourishing, most dimensions were either not associated with these outcomes or were related to lower levels of these outcomes. These findings can inform new prevention and intervention programs to help Black women thrive. [ABSTRACT FROM AUTHOR]

Aim: To assess the efficacy of aspirin use for primary prevention of cardiovascular disease (CVD) with incident atherosclerotic CVD and mortality in high‐risk type 2 diabetes. Method s : In this post hoc analysis, we included participants in the ACCORD trial without CVD at baseline. The association between aspirin use and the primary outcome (a composite of nonfatal myocardial infarction, nonfatal stroke or cardiovascular [CV] death) and all‐cause mortality was evaluated using Cox proportional hazard analysis adjusting for demographics, CV risk factors and comorbidities. Results: Eligible participants (n = 6330) were aged 62.8 ± 5.9 years at baseline, 43.8% of the participants were female, and 3026 (47.8%) used aspirin. Over a median (interquartile range) follow‐up of 4.9 (4.1–5.7) years, the number (%) of primary outcome and all‐cause mortality events in those who used aspirin (vs. those who did not), was 196 (6.5) versus 229 (6.9) and 146 (4.8) versus 147 (4.5), respectively. The adjusted hazard ratios (95% confidence interval) associated with aspirin use for the primary outcome and all‐cause mortality were 0.94 (0.77–1.14) and 1.08 (0.85–1.36), respectively. Conclusion: In high‐risk individuals with type 2 diabetes, the use of aspirin for primary prevention was not associated with a decreased risk of incident CVD or all‐cause mortality. [ABSTRACT FROM AUTHOR]

This paper explores cognitive place associations; conceptualised as a place‐based mental model that derives subconscious links between geographic locations. Utilising a large corpus of online discussion data from the social media website Reddit, we experiment on the extraction of such geographic knowledge from unstructured text. First we construct a system to identify place names found in Reddit comments, disambiguating each to a set of coordinates where possible. Following this, we build a collective picture of cognitive place associations in the United Kingdom, linking locations that co‐occur in user comments and evaluating the effect of distance on the strength of these associations. Exploring these geographies nationally, associations were shown to be typically weaker over greater distances. This distance decay is also highly regional, rural areas typically have greater levels of distance decay, particularly in Wales and Scotland. When comparing major cities across the UK, we observe distinct distance decay patterns, influenced primarily by proximity to other cities. [ABSTRACT FROM AUTHOR]

Clinical Scenario: Sport-related injuries are a common occurrence within the athletic population and every athlete responds differently. The cognitive, emotional, and behavioral responses associated with injuries ultimately impact the injury rehabilitation process and return to play. Specifically, self-efficacy significantly impacts the rehabilitation process and psychological techniques to improve self-efficacy are crucial in the recovery process. Imagery is one of these beneficial techniques. Clinical Question: Does the use of imagery during injury rehabilitation improve self-efficacy of rehabilitation capabilities compared with rehabilitation alone in athletes with a sport-related injury? Summary of Key Findings: The current literature was searched to identify the effects of imagery use to improve self-efficacy of rehabilitation capabilities, and 2 studies were selected: a mixed methods ecologically valid design and randomized controlled trial. Both studies investigated the relationship between imagery and self-efficacy and found positive results for imagery use in rehabilitation. Additionally, one of the studies specifically assessed rehabilitation satisfaction and found positive results. Clinical Bottom Line: The use of imagery should be considered as a clinical option for increasing self-efficacy during injury rehabilitation. Strength of Recommendation: Based on the Oxford Centre for Evidence-Based Medicine strength of recommendation, there is a grade B of recommendation to support the use of imagery to improve self-efficacy of rehabilitation capabilities during an injury rehabilitation program. [ABSTRACT FROM AUTHOR]

Over the past 20+ years, researchers have worked toward identifying early behavioral predictors of autism spectrum disorder (ASD) and developing observation-based screeners to supplement existing parent-report methods. This study is a follow-up, 3 to 8 years later, with parents/caregivers of 57 children previously enrolled in a U.S. university-based study evaluating early ASD-risk. The original study evaluated infants' (ages 15–35 months) ASD-risk through both observation-based and parent-report screeners. At follow-up, caregivers completed a phone interview inquiring about their child's developmental progress and diagnostic outcomes. Results indicated screener at-risk status agreement in infancy predicted only one of the four parent-reported ASD diagnoses at follow-up. Single instrument at-risk status aligned with two additional ASD diagnoses (one per screener), and both screeners missed one ASD diagnosis at follow-up. Results did not indicate significant added utility for the observation-based screener over the commonly used parent-report screener, suggesting that ASD behavioral markers may be hard to observe at early ages. [ABSTRACT FROM AUTHOR]

Research on the acquisition of American Sign Language (ASL) by deaf autistic children has documented similarities to the linguistic profile of hearing children on the autism spectrum and has identified sign-specific phenomena that could serve as clinical markers of autism in the deaf population. However, the acquisition of a signed language by deaf autistic individuals whose language use appears to be at age-level is not well documented. Here we present a case study of ASL use by a Deaf autistic adolescent exposed to ASL since birth. Data include two video recordings (collected at age 16;11 and 17;4 years) of his spontaneous ASL. Utterances were coded for repetitions, phonological form, fingerspelling, metalinguistic awareness, and facial expressions having grammatical functions. Other data include a writing sample (17;6) and background information obtained from parental interviews and formal psycho-educational evaluations (between ages 14 and 17). Results revealed this adolescent has strong ASL skills including sophisticated vocabulary and semantic content, advanced fingerspelling, and evidence of metalinguistic awareness. His distinctive signing patterns include abundant repetition of phrases, intrusion of non-ASL handshapes, articulation disfluency, reduced facial expressiveness, and a dissociation between fingerspelling and writing skills. The results of this study diversify and broaden discussions of the ways that autism may interact with language development, especially in the visual-gestural modality. Understanding language patterns in autistic signers more fully will improve identification of autism in the deaf population, promote acceptance of diverse signing patterns in the Deaf community, and lead to better support for this population. [ABSTRACT FROM AUTHOR]

• African Americans have been underrepresented in mindfulness research. • Mindfulness approaches need to be tailored for African Americans. • Mindfulness interventions can be disseminated via technology to reduce barriers. • A culturally-responsive mindfulness app improved outcomes among African Americans. Mindfulness is a promising health promotion strategy for African Americans, and it is imperative that culturally responsive mindfulness approaches be accessible to this population. One way to address this need is to develop and test if culturally responsive mobile health (mhealth) applications are efficacious in reducing stress-related outcomes in this population. With this goal in mind, we employed a repeated-measures randomized control trial (RCT) across a 12-week intervention period to evaluate if participants in the intervention group outperformed a wait-list control group in reductions in stress, depressive symptoms, anxiety, emotional regulation difficulties as well as in increases in self-compassion, resilience, and mindfulness attitudes and behaviors. Our sample included 170 Black/African American participants who were randomly assigned to either the intervention condition (n = 84) or the wait-list control group (n = 86). Participants in the intervention condition reported more self-compassion, used more mindfulness, and had greater self-efficacy using mindfulness; yet, no other differences were evident. Participants expressed high levels of satisfaction with the app and gave it a positive rating for its relevance to their lives. These findings support the efficacy of a culturally responsive mindfulness mHealth app to enhance self-compassion and increase the use of health-promoting behaviors, like mindfulness, among African Americans. Implications for future research are discussed. [ABSTRACT FROM AUTHOR]

A leading concern about single IRB (sIRB) review for multisite studies, as is now required by federal policies, is whether and how sIRBs consider local context in their review. While several types of local context considerations have been proposed, there is no shared agreement among those charged with the ethics oversight of human subjects research as to the goals and content of local context review, nor the types of research studies for which sIRB review might be inappropriate. Through a scoping review of published scholarship, public comments, and federal guidance documents, we identified five assumed goals for local context review: protecting the rights and welfare of local participants; ensuring compliance with applicable laws and policies; assessing feasibility; promoting the quality of research; and promoting procedural justice. While a variety of content was proposed to be relevant, it was largely grouped into four domains: population/participant‐level characteristics; investigator and research team characteristics; institution‐level characteristics; and state and local laws. Proposed characteristics for exclusion from sIRB requirements reflected both protection‐ and efficiency‐based concerns. These findings can inform ongoing efforts to assess the implications of policies mandating sIRB review, and when exceptions to those policies might be appropriate. [ABSTRACT FROM AUTHOR]

This study examines how Black journalists in local legacy newspapers, digital startup media and historically Black newspapers have expressed journalistic objectivity and enacted journalistic roles. Findings showed more neutral coverage in historically white media, which was expected, while coverage in the historically Black newspaper and the digital startup reflected an advocacy role—one that did not fit within the four expected roles. Also, a "clarifier" role emerged in which journalists encouraged local protest groups to distinguish their identities. [ABSTRACT FROM AUTHOR]

Mindfulness training has shown to improve well-being in student populations. Yet, the benefits for Black students have not been adequately explored. This study investigated the effects of a brief mindfulness program on mood, mindfulness, cognition, and physiological indicators of stress in a small cohort of Black undergraduate women. Participants took part in a 4-week mindfulness-based stress reduction program (MBSR). Before and after the program, participants were assessed with the Kentucky Inventory of Mindfulness Skills, Profile of Mood States, Perceived Stress Scale, Corsi block tapping test, N-back task, and Stroop Color and Word test. Blood pressure, pulse wave velocity, augmentation index, salivary cortisol, and C-reactive protein were also measured. Significant improvements were observed in mindfulness skills, working memory, and cognitive processing. Reductions in tension-anxiety, fatigue, confusion, total overall mood disturbance, and arterial stiffness were also found. All other measures remained unchanged. This is the first study to demonstrate that MBSR training improves psychological, cognitive, and cardiovascular factors associated with stress in college-aged Black women. Limitations and directions for future research are also discussed. [ABSTRACT FROM AUTHOR]

This research letter discusses a novel model for low vision screening and evaluation in hospitalized older adults. The study was conducted at the Ralph H. Johnson VA Health Care System (RHJVAHCS) Acute Care of the Elderly (ACE) unit, where comprehensive visual assessments and interventions were provided at the bedside. The study found that a high percentage of patients benefited from visual impairment identification and intervention, highlighting the importance of addressing visual health in the acute care setting. The study also identified barriers and challenges to implementing this model and provided recommendations for improvement. [Extracted from the article]

The vertebrate enteric nervous system (ENS) is a crucial network of enteric neurons and glia resident within the entire gastrointestinal tract (GI). Overseeing essential GI functions such as gut motility and water balance, the ENS serves as a pivotal bidirectional link in the gut-brain axis. During early development, the ENS is primarily derived from enteric neural crest cells (ENCCs). Disruptions to ENCC development, as seen in conditions like Hirschsprung disease (HSCR), lead to the absence of ENS in the GI, particularly in the colon. In this study, using zebrafish, we devised an in vivo F0 CRISPR-based screen employing a robust, rapid pipeline integrating single-cell RNA sequencing, CRISPR reverse genetics, and high-content imaging. Our findings unveil various genes, including those encoding opioid receptors, as possible regulators of ENS establishment. In addition, we present evidence that suggests opioid receptor involvement in the neurochemical coding of the larval ENS. In summary, our work presents a novel, efficient CRISPR screen targeting ENS development, facilitating the discovery of previously unknown genes, and increasing knowledge of nervous system construction. [ABSTRACT FROM AUTHOR]

This paper introduces a unique finite element analysis (FEA) technique designed to predict elastic response in polymer matrix composites (PMCs). Extensive research has been conducted to model the manufacturing process of multiple 'L'-shaped components, fabricated from SPRINTTM materials (GLP 43 and GLP 96) at two thicknesses (15 mm and 25 mm). Three distinct FEA methodologies were utilised to determine the impact of thermal loads and rigid fixtures. An error deviation of 3.23% was recorded when comparing simulation results to experimental data, thereby validating the effectiveness of the FEA methodology. [ABSTRACT FROM AUTHOR]

Over 18 million people worldwide were diagnosed with cancer in 2020, including over 150,000 people in Australia. Although improved early detection and treatment have increased the survival rates, cardiotoxic treatment and inadequate management of cardiovascular risk factors have resulted in cardiovascular disease (CVD) being one of the leading causes of non-cancer-related death and disability among cancer survivors. International guidelines outline the standards of care for CVD risk surveillance and management. However, Australian cardio-oncology policies and clinical guidelines are limited. There is increasing growth of cardio-oncology research in Australia and support from leading Australian professional bodies and advocacy and research networks, including the Cardiac Society of Australia and New Zealand, the Clinical Oncology Society of Australia, the National Heart Foundation of Australia, and the Australian Cardiovascular Alliance (ACvA). Thus, opportunities to drive multidisciplinary cardio-oncology initiatives are growing, including grant funding, position statements, and novel research to inform new policies. The ACvA has a unique flagship structure that spans the translational research pipeline from drug discovery to implementation science. This article aims to highlight how multidisciplinary cardio-oncology innovations could intersect with the seven ACvA flagships, and to showcase Australian achievements in cardio-oncology thus far. We summarise eight key priority areas for future cardio-oncology research that emerged. These strategies will strengthen cardio-oncology research and care in Australia, and drive new guidelines, policies, and government initiatives to ensure equity in health outcomes for all cardio-oncology patients. [ABSTRACT FROM AUTHOR]

Intrinsically disordered regions (IDRs) are segments of proteins without stable three-dimensional structures. As this flexibility allows them to interact with diverse binding partners, IDRs play key roles in cell signaling and gene expression. Despite the prevalence and importance of IDRs in eukaryotic proteomes and various biological processes, associating them with specific molecular functions remains a significant challenge due to their high rates of sequence evolution. However, by comparing the observed values of various IDR-associated properties against those generated under a simulated model of evolution, a recent study found most IDRs across the entire yeast proteome contain conserved features. Furthermore, it showed clusters of IDRs with common "evolutionary signatures," i.e. patterns of conserved features, were associated with specific biological functions. To determine if similar patterns of conservation are found in the IDRs of other systems, in this work we applied a series of phylogenetic models to over 7,500 orthologous IDRs identified in the Drosophila genome to dissect the forces driving their evolution. By comparing models of constrained and unconstrained continuous trait evolution using the Brownian motion and Ornstein-Uhlenbeck models, respectively, we identified signals of widespread constraint, indicating conservation of distributed features is mechanism of IDR evolution common to multiple biological systems. In contrast to the previous study in yeast, however, we observed limited evidence of IDR clusters with specific biological functions, which suggests a more complex relationship between evolutionary constraints and function in the IDRs of multicellular organisms. Author summary: Proteins are the molecular machines that carry out many processes required for life at an atomic level. Though many proteins use fixed structures to perform their functions, proteins with flexible segments are widespread, especially in multicellular organisms. Furthermore, these intrinsically disordered regions (IDRs) are often involved in essential cellular functions. However, the sequences of IDRs evolve quickly, which challenges traditional bioinformatics methods that depend on sequence conservation to predict function. Several studies have demonstrated that distributed biophysical features of IDRs are constrained rather than their exact sequences, and a recent study in yeast found that IDRs with common patterns of conserved features were associated with specific functions. Therefore, in this work we ask if IDRs in fruit flies, another common laboratory organism, also have patterns of conservation with associated functions. We build on the previous study by integrating their approach into a fully statistical framework based on mathematical models of trait evolution. Though we identify widespread signals of conservation in the IDRs of fruit flies, we find less evidence of a simple relationship between features and function. These methods and results will provide a valuable resource that can guide future experimental analyses of IDRs in fruit flies and other organisms. [ABSTRACT FROM AUTHOR]

This case study investigated waste management in a small, rural, Queensland hospital identifying areas where staff could reduce CO2e within the context of what is logistically possible. Phase I captured waste streams and disposal data for 1 May 2022–31 May 23 in a 20-bed Queensland Health hospital and included three audits of the hospital’s pharmaceutical waste bin. Phase II comprised semi-structured interviews with seven staff. Most potentially recyclable waste was being disposed of in the clinical, pharmaceutical, and general waste streams. All participants were interested in recycling more if appropriate bins were accessible in their work and lunch areas and recycling education was provided. Between 1 May 2022 and 31 May 2023, the CO2e were 44.53t, which equates to approximately 48,327 car km. This study identified opportunities for hospital-wide recycling which would reduce CO2e, waste collection fees, and landfill volume. A limitation was the small number of interviewees due to rural workforce shortages and a COVID-19 outbreak. [ABSTRACT FROM AUTHOR]

This study examined sex-specific associations between sexual violence (SV) type and physical activity, and identified associations between PTSD symptoms and physical activity, all among cisgender men and women survivors of SV. Cross-sectional data from men (n = 197) and women (n = 356) survivors of SV were analyzed with stratified (men; women) hierarchical logistic regressions. Additionally, fully adjusted models for the total sample included interaction terms to further assess whether associations between SV type as well as PTSD symptoms (sum, clusters) and physical activity differed significantly by sex. Sexual assault was negatively associated with physical activity in the crude model among women (ORs: 0.58; p < 0.05). Harassment was positively associated with physical activity in the crude and adjusted models (ORs:1.92–2.16; ps<0.05) among women. Among men, there were no significant relationships. Regarding PTSD symptoms among women, crude and adjusted stratified models identified significant positive relationships with intrusion (ORs: 1.18–1.22; ps<0.05). Crude and adjusted models revealed significant positive relationships between avoidance and activity (ORs:1.38–1.41; ps<0.05) among men but not women. The interaction term for this difference in the association between avoidance and physical activity by sex was significant (OR: 0.65; 95%CI: 0.48–0.88; p < 0.01). Overall, findings provide evidence for sex-specific associations between SV and physical activity. [ABSTRACT FROM AUTHOR]

Internalization of culturally dominant masculine gender role norms can have harmful impacts on the physical and emotional health of men and boys. Although parents play an important role in influencing gender-related beliefs in their children, limited research has examined how contemporary parents conceptualize masculinity and their role in gender socialization. The present study conducted 13 focus groups with Black, Latino, and White parents (N = 83) of school-age boys from rural and urban areas in a large Southeastern state in the United States. Parent beliefs about masculinity existed across a spectrum from "rigid" (representing narrow, culturally dominant masculine norms) to "flexible" (defining a broader set of behaviors and attitudes as masculine). In general, more flexible beliefs were expressed by mothers than fathers and by White than Black and Latino parents. Most parents reacted positively to messages about potential harms associated with restrictive masculinity norms; however, many saw these issues primarily as parenting challenges (e.g., teaching boys to resist negative peer influences) rather than related to gender socialization. Some unique themes also emerged within racial/ethnic groups, with Black parents noting the impact of racial discrimination on societal expectations for Black men and fathers and Latino parents describing generational shifts toward more equitable gender role attitudes and parenting practices. These findings highlight the need for more complex and nuanced messages about masculinity norms and their relationship to health and well-being and can help inform the development of interventions to promote healthy masculine gender socialization, increase health equity, and prevent injury and violence. Public Significance Statement: Culturally dominant masculine gender role norms (e.g., emotional stoicism, social and physical dominance, independence, toughness) are associated with negative social and health consequences for boys and men, along with public health and safety concerns related to risk behaviors and violence perpetration. Parents and caregivers of young boys are an ideal target for preventative interventions addressing these norms in early and middle childhood, when gender socialization begins. Findings from this study suggest variation by gender and race/ethnicity in contemporary parents' attitudes toward masculinity and norms-challenging messages about parenting boys and can inform the development of social norms-based and parenting interventions to improve health equity and address multiple public health concerns, including injury and violence. [ABSTRACT FROM AUTHOR]

The article discusses a financial literacy event hosted by the Atlanta University Center Robert W. Woodruff Library, introducing a new business librarian and promoting financial literacy within the AUC community during Money Smart Week. Topics include the event's organization, activities such as workshops and resource browsing, and positive feedback emphasizing the importance of financial education.

There is an inverted u‐shaped relationship between age and wages in most labor markets, but the effects of age on productivity are often unclear. We use panel data in a market of high earners, professional footballers (soccer players) in North America, to estimate age‐productivity and age‐wage profiles. We find stark differences; wages increase for several years after productivity has peaked, before dropping sharply at the end of a career. This poses the question: why are middle‐aged workers seemingly overpaid? We investigate a range of possible mechanisms that could be responsible, only finding evidence that tentatively supports a talent discovery theory. [ABSTRACT FROM AUTHOR]

Cervical laminoplasty is an increasingly popular surgical option for the treatment of cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL). Over the past few decades, there have been substantial developments in both surgical technique and hardware options. As the field of cervical surgery rapidly evolves, there is a timely need to reassess the evolving complications associated with newer techniques. This review aims to synthesize the available literature on cervical laminoplasty and associated mechanical complications pertaining to different laminoplasty hinge fixation options. [ABSTRACT FROM AUTHOR]

This article consists of an introduction to the theory of nonassociative geometric classical and quantum information flows defined by star products with R‐flux deformations in string gravity. Corresponding nonassociative generalizations of the concepts of classical Shannon entropy, quantum von Neumann entropy, Rényi entropy are formulated. The fundamental geometric and quantum information objects are computed following the Grigori Perelman statistical thermodynamic approach to Ricci flows and gravity theories generalized for phase spaces modeled as (co) tangent Lorentz bundles. Nonassociative parametric deformations and nonholonomic thermo‐geometric versions of statistical generating functions, their quantum analogues as density matrices are considered for deriving the entropy, energy and fluctuation functionals. This allows us to define and compute respective classical and quantum relative and conditional entropies, mutual information and nonassociative entanglement and thermodynamic information variables. The principles of nonassociative quantum geometric and information flow theory, QGIF, and study the basic properties of such quasi‐stationary models related to modified gravity theories are formulated. Applications are considered for nonassociative deformed and entangled couples of four‐dimensional (4‐d), wormholes (defined by respective spacetime and/or momentum type coordinates) and nonassociative QGIFs of 8‐d phase space generalized wormholes configurations. Finally, phase space black holes and wormholes being transversable for nonassociative qubits, quantum channels and entanglement witness are speculated; thought and laboratory experiments are discussed; and perspectives for quantum computer modeling and tests of nonassociative geometric flow and gravity theories are considered. [ABSTRACT FROM AUTHOR]

This analysis reported interest in exercise programs made for men survivors of sexual violence (SV), preferences for the structure and content of these programs, and comparisons by physical activity level and PTSD status. A cross-sectional survey was conducted among 198 men aged 18–65, with a history of SV, in the USA. Most respondents indicated interest in exercise programs for them. Men with PTSD were most interested. Men favored exercising at-home, alone, with a male instructor, 3–4 times per week, at moderate intensity, for 30 mins-1 h. No differences in preferences were found by activity status. Differences by PTSD status were found in location, social environment, instructor gender, intensity, duration, and program length. Top modes were walking, jogging, and biking. Results add new knowledge relevant for integrating exercise into trauma recovery programs. [ABSTRACT FROM AUTHOR]

Aims and Objectives: To map out the primary research studies relating to how virtual reality (VR) has been used to distract children and young people with long‐term conditions from pain or pruritus. Background: Pharmacologic treatment of chronic pain and pruritus may have side effects; hence, non‐invasive non‐pharmacological treatments are being sought. Design: The scoping review followed the methodology recommended by the Joanna Briggs Institute, PAGER framework and PRISMA‐ScR checklist. The protocol was registered with the Open Science Registration on 14 February 2022 https//doi.org/10.17605/OSF.IO/K2R93. Methods: Five databases (Medline, CINAHL, PsycINFO, Web of Science and Scopus) were searched. Data were extracted from primary research studies published between 2000 and 2022 involving children and adolescent populations (<21 years) with a long‐term condition that had an element of enduring pruritus and/or pain. Results: Of 464 abstracts screened, 35 full‐text papers were assessed with 5 studies meeting the eligibility criteria. Three main themes emerged from the included studies: (1) Improvements in pain and daily functioning; (2) positive perceptions of VR and (3) accessibility and feasibility of VR. No papers were found on the effect of VR on alleviating pruritus. Conclusion: VR is feasible, acceptable, and safe for children and adolescents with chronic pain in a range of long‐term conditions and offers promise as an adjunctive treatment for improving chronic pain and quality of life. No studies were identified that targeted pruritis or measured pruritis outcomes; thus, the effects of VR for pruritis are unknown. There is a need for rigorously designed, randomised controlled trials to test the clinical and cost‐effectiveness of VR interventions for chronic pain and pruritis in children and adolescents. The use of the PAGER (Patterns, Advances, Gaps, Evidence for Practice and Research Recommendations) framework for scoping reviews helped to structure analysis and findings and identify research gaps. Relevance to Clinical Practice: VR interventions offer promise in improving chronic pain related to long‐term conditions. [ABSTRACT FROM AUTHOR]

Sox11, a member of the SoxC family of transcription factors, has distinct functions at different times in neural development. Studies in mouse, frog, chick, and zebrafish show that Sox11 promotes neural fate, neural differentiation, and neuron maturation in the central nervous system. These diverse roles are controlled in part by spatial and temporal-specific protein interactions. However, the partner proteins and Sox11-interaction domains underlying these diverse functions are not well defined. Here, we identify partner proteins and the domains of Xenopus laevis Sox11 required for protein interaction and function during neurogenesis. Our data show that Sox11 co-localizes and interacts with Pou3f2 and Neurog2 in the anterior neural plate and in early neurons, respectively. We also demonstrate that Sox11 does not interact with Neurog1, a high-affinity partner of Sox11 in the mouse cortex, suggesting that Sox11 has species-specific partner proteins. Additionally, we determined that the N-terminus including the HMG domain of Sox11 is necessary for interaction with Pou3f2 and Neurog2, and we established a novel role for the N-terminal 46 amino acids in the specification of placodal progenitors. This is the first identification of partner proteins for Sox11 and of domains required for partner-protein interactions and distinct roles in neurogenesis. [ABSTRACT FROM AUTHOR]

Did government mines inspectors in late Victorian Britain display overt bias towards employers when assigning blame for fatal underground explosions? Inspectors were closer to managers and coal owners than they were to miners or mine supervisors in terms of status, background, and engineering experience. That inspectors had more in common with management could have led to favouritism or regulatory capture, as was suggested at the time by miners and more recently by historians. To adjudicate these claims, this article applies the technique of qualitative content analysis to the comments of mines inspectors in their published annual reports. The findings reveal that inspectors frequently condemned employers and their representatives, especially after gas and coal dust explosions that took 10 or more lives. By contrast, following blasting explosions, which typically killed only one person, they usually blamed the miners themselves. The available evidence therefore suggests that any discernible pro-employer bias on the part of the inspectorate was limited to smaller explosions where it was easier to ignore systemic factors and deem individual workmen to be at fault. [ABSTRACT FROM AUTHOR]

This article investigates urban change, making films from research approaches which use ethnographic walking interviews, public walking tours and psychogeographic techniques. The case study focuses on Newport, South Wales, UK. Using this example, I explore the longer-term impacts of the (mostly) state-led reconfiguration of British towns and cities from the late-1950s to the mid-1970s. Contemporary film for this period sets the context and links to Guy Debord's concept of psychogeography, psychogeography in film, and associated walking techniques. This article builds a methodology from these principles, where one-to-one participant-led walking interviews – both outdoor and using online maps – reacquaint people over aged 55 with earlier periods of their biographies. These approaches reveal deeply-held memories and articulate feelings relevant to the present and future. This article develops and analyses practice, offering ways to film walking tours to sensitivity present and explore place narratives over time: firstly, working with community activists to reveal the politics of local housing; and secondly, a commission with a theatre company where three artists follow a specific walking route which explores urban change and rights to the city. As towns and cities face challenges these approaches offer visual methods to engage the public in place making. [ABSTRACT FROM AUTHOR]

This article provides an overview of the impact of rodents on agriculture, health, and biodiversity, with a particular focus on Africa. It acknowledges that while rodents make up a significant portion of mammalian species, only a small percentage of them have negative effects. The article highlights the 7th International Conference on Rodent Biology and Management, which concentrated on rodent biology and biodiversity in African highlands and mountains. It discusses the shift in focus from previous conferences, including increased research on fertility control of rodents and a greater emphasis on the One Health approach to rodent-borne diseases. The article covers various topics related to rodent biology and management, such as reducing flea and rodent populations simultaneously to prevent disease transmission and efforts in New Zealand to eradicate invasive rodents for the conservation of endemic wildlife. It also explores adaptations of rodent sensory systems, developments in rodent taxonomy, strategies for dealing with dietary toxins, and the use of African giant pouched rats for tasks like landmine detection and disease detection. The article underscores the importance of long-term population studies in understanding rodent populations and their impact on agriculture and human health. It concludes by acknowledging the contributions of researchers in the field and announcing the next International Conference on Rodent Biology and Management in 2025. [Extracted from the article]

Objective: To determine whether alcohol use leads to prolonged clinical recovery or increased severity of concussion symptoms in National Collegiate Athletic Association (NCAA) athletes. Design: Prospective observational study. Setting: Clinical institutions. Participants: Athletes from the NCAA Concussion Assessment Research and Education consortium who sustained a concussion from 2014 to 2021. Interventions: Athletes were divided into 2 groups, those reporting alcohol use postinjury and those reporting no alcohol use postinjury. Main Outcome Measures: Symptom recovery was evaluated as time (in days) from injury to clearance to return to unrestricted play (days until URTP). Severity of concussion symptoms was assessed using the Standardized Sport Concussion Assessment Tool (SCAT3) symptom severity, headache severity, difficulty concentrating, and difficulty remembering scores. These scores were taken a median of 6.6 [interquartile range (IQR) = 4.0-10] and 6 (IQR = 4.0-9.0) days after injury for those who did and did not consume alcohol postinjury respectively and compared with baseline SCAT3 scores. Results: Four hundred eighty four athletes from the data set had complete data for exposure and outcome. The adjusted mean number of days until URTP for athletes reporting alcohol use postinjury [23.3; 95% confidence interval (CI), 20.0-27.2; days] was incidence rate ratio (IRR) 1.32 (95% CI, 1.12-1.55; P < 0.001) times higher than for athletes who reported no alcohol use postinjury [17.7 (95% CI, 16.1-19.3) days]. Postinjury alcohol was not associated with severity of concussion symptoms (P's < 0.05). Conclusion: Self-reported postinjury alcohol use is associated with prolonged recovery but not severity of concussion symptoms in collegiate athletes. This may inform future clinical recommendations regarding alcohol consumption after concussion. [ABSTRACT FROM AUTHOR]

This article explores the potential of military strategies to enhance the resilience and effectiveness of civilian supply chains. The recent pandemic underscored the vulnerabilities of these supply chains, prompting a need for robust solutions. This article investigates this through a comparative analysis of military and civilian supply chain models, drawing insights from primary (semi-structured interviews) and secondary sources (literature review). Key military strategies such as contingency planning, rapid deployment, and adaptive leadership are discussed. Hence providing practical strategies for their integration into civilian operations and considering the challenges. The article concludes by emphasizing the importance of adaptive leadership in navigating crises, offering a new lens for future research within the realms of national security and economic stability. The aim is to equip civilian supply chain leaders with comprehensive strategies to enhance their resilience and effectiveness during crises. [ABSTRACT FROM AUTHOR]

This article examines the Attlee government's performance as a crisis manager in relation to tobacco policy in the years prior to the publication in 1950 of research linking smoking and cancer. Health concerns played no role in tobacco policy before 1950, and the government hoped more teenagers would take up smoking and pay tobacco duty. Tobacco took on added significance as an economic issue because policy-makers had so little room for manoeuvre. Their task was to balance the desire of consumers to smoke as much as they liked at a reasonable price, the exchequer's need to raise revenue from tobacco duties, and the imperative to conserve scarce dollars. Tobacco was an economic and financial rather than a health issue in the late 1940s and the authorities juggled competing demands creditably. This article examines previously neglected but important aspects of the histories of tobacco and of the Attlee government's economic policies. [ABSTRACT FROM AUTHOR]

The new religion of Spiritualism emerged in the mid-19th century. Through mediumship, Spiritualists contacted the dead, believing them to have "passed over" to another plane of existence. It spread from America to Great Britain before arriving in Australia in the 1850s. This article charts the history of the world's oldest continuously running Spiritualist organisation, the Victorian Spiritualists' Union (VSU, est. 1870), exploring the unexpected survival of the movement in Australia. It challenges the common idea that Spiritualism enjoyed only a brief revival in the interwar period and has maintained a tenuous status ever since. Rather, I argue that Spiritualism has experienced several peaks and troughs since its emergence in Australia, including a widespread revival in the 1970s, spearheaded by the VSU. Spiritualism in Australia survives due to the development of a church movement, the advocacy of groups such as the VSU, the generous volunteer efforts of individual Spiritualists, the acquisition of church buildings, and its geographic mobility, all of which have allowed Spiritualist churches to be responsive to changing social and cultural conditions for more than a century. It is one of Australia's largest and most resilient alternative religious movements, not simply a Victorian-era curio. [ABSTRACT FROM AUTHOR]

African American women have been protected against death by suicide, and it is important to determine factors that protect against suicide in this population. Racial identity, which shapes African Americans' self-concept, may cultivate facets of well-being among African American women. We investigated the relations among racial identity profiles and well-being, namely reasons for living, existential well-being, and suicide resilience, among 198 African American women with a recent suicide attempt. Using latent profile analysis, we found that racial identity profiles characterized by higher racial group identification and more positive feelings about being African American were associated with greater reasons for living, existential well-being, and suicide resilience. Ideas for culturally responsive interventions are proposed. [ABSTRACT FROM AUTHOR]

Implementation fidelity has been an important issue in the service provision and associated outcomes of Wraparound, an intensive, individualized care planning process that uses a team-based approach to integrate youth into the community to minimize the need for intensive, institutional services. In response to the growing need to monitor fidelity to the Wraparound process, a variety of instruments have been created and tested. In this study, the authors present the results of several analyses designed to better understand the measurement characteristics of the Wraparound Fidelity Index Short Form (WFI-EZ), a multi-informant fidelity instrument. The results from our analysis of 1027 WFI-EZ responses indicate that the internal consistency of the instrument is very good, although the negatively worded items did not appear to function as well as positively worded items. Results from two confirmatory factor analyses were unable to validate the original domains identified by the instrument developers, but for certain outcomes the WFI-EZ demonstrated deseriable predictive validity. Preliminary evidence is also provided that WFI-EZ responses likely differ by respondent type. We conclude by discussing the implications of using the WFI-EZ in programming, policy, and practice considering the findings of our study. [ABSTRACT FROM AUTHOR]

Identifying protein sequences with common ancestry is a core task in bioinformatics and evolutionary biology. However, methods for inferring and aligning such sequences in annotated genomes have not kept pace with the increasing scale and complexity of the available data. Thus, in this work, we implemented several improvements to the traditional methodology that more fully leverage the redundancy of closely related genomes and the organization of their annotations. Two highlights include the application of the more flexible k-clique percolation algorithm for identifying clusters of orthologous proteins and the development of a novel technique for removing poorly supported regions of alignments with a phylogenetic hidden Markov model (phylo-HMM). In making the latter, we wrote a fully documented Python package Homomorph that implements standard HMM algorithms and created a set of tutorials to promote its use by a wide audience. We applied the resulting pipeline to a set of 33 annotated Drosophila genomes, generating 22,813 orthologous groups and 8,566 high-quality alignments. [ABSTRACT FROM AUTHOR]

This study reported on perceived benefits and barriers of exercise among men with histories of sexual violence (SV) and compared these perceptions by activity level and post-traumatic stress disorder (PTSD) status. An online, cross-sectional, survey of men with histories of SV (N = 198) was completed using Amazon Mechanical Turk. Inclusion criteria were identifying sex at birth as male, age between 18 and 65 years, self-reported history of SV, and living in the United States (U.S.). A total of 1,260 men were screened for the study, of which 316 met the inclusion criteria, and 198 met all data quality requirements and were included in the study. Sociodemographic information, exercise behavior, PTSD symptoms, and perceived exercise barriers/benefits were collected. Comparisons by activity and PTSD status were analyzed. Additionally, two open-ended qualitative research questions were included to provide nuance to perceived barriers/benefits of exercise. The most salient benefits included physical performance, psychological outlook, and preventative health. Open-ended responses also noted the mental and physical benefits of exercise. The most salient barrier was physical exercise, with open-ended responses emphasizing lack of time, chronic pain and health concerns, and poor mental health and lack of motivation as impediments to exercise. Significant differences were found in benefits (psychological outlook, physical performance) and barriers (exercise environment, high time expenditure, and family discouragement) between active and insufficiently active men with histories of SV (p s <.05; Cohen's d s = 0.32–0.57). Significant differences were found by PTSD status on benefits (physical performance, social interaction, and preventative health) and barriers (exercise milieu, time expenditure, hard physical exercise, family discouragement) (p s <.05; Cohen's d s = 0.40–1.10). Findings provide new gender-specific strategies for promoting exercise among men with histories of SV: integrating exercise physiologists into trauma recovery programs, psychoeducation, engaging friends and family members, peer-support, and building self-efficacy. [ABSTRACT FROM AUTHOR]