135 results on '"Vapiwala, Neha"'
Search Results
2. The Fallacy of the Consultation and Informed Consent Process in Radiation Oncology Through the Lens of Prostate Cancer.
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Ennis, Ronald D. and Vapiwala, Neha
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PROSTATE cancer , *ONCOLOGY , *RADIATION , *INFORMED consent (Medical law) , *MEDICAL referrals , *RADIOTHERAPY , *PROSTATE tumors - Published
- 2021
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3. Sociodemographic and geographic factors impacting radiotherapy recommendation, initiation, and completion for patients with cancer.
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Hogan, Jacob S., Orav, E. John, Vapiwala, Neha, and Lam, Miranda B.
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BLACK people , *SOCIODEMOGRAPHIC factors , *CANCER treatment , *RACE , *CANCER hospitals - Abstract
Background Methods Results Conclusions More than half of patients with cancer receive radiotherapy, which often requires daily treatments for several weeks. The impact of geographic and sociodemographic factors on the odds of patients with cancer being recommended radiotherapy, starting radiotherapy, and completing radiotherapy is not well understood.This was a retrospective patient cohort study that included patients diagnosed with one of the 10 most common solid cancers from January 1, 2018, to December 31, 2021, in the National Cancer Database. The primary predictor was radial distance from a patient’s home to their cancer treatment hospital. Other covariates included baseline patient characteristics (age, sex, comorbidities, metastatic disease, cancer site), sociodemographic characteristics (race, ethnicity, median income quartile, insurance status), geographic region, and facility type. The three primary outcomes were being recommended radiotherapy, starting recommended radiotherapy, and completing radiotherapy.Of the 3,068,919 patients included, patients living >50 miles away had lower odds of being recommended radiotherapy than those living <10 miles away. Compared to White patients, Asian and Hispanic patients had lower odds of being recommended radiotherapy, and Black patients had lower odds of starting recommended radiotherapy. Uninsured patients, those with Medicaid or Medicare, and patients in lower median income quartiles had lower odds of starting or completing radiotherapy.Geographic and sociodemographic factors impact access to radiotherapy at different levels in cancer care and understanding these factors could aid policymakers and practices in identifying and supporting at‐risk patients. [ABSTRACT FROM AUTHOR]
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- 2024
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4. A Pooled Toxicity Analysis of Moderately Hypofractionated Proton Beam Therapy and Intensity Modulated Radiation Therapy in Early-Stage Prostate Cancer Patients.
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Vapiwala, Neha, Wong, J. Karen, Handorf, Elizabeth, Paly, Jonathan, Grewal, Amardeep, Tendulkar, Rahul, Godfrey, Devon, Carpenter, David, Mendenhall, Nancy P., Henderson, Randal H., Stish, Bradley J., Vargas, Carlos, Salama, Joseph K., Davis, Brian J., and Horwitz, Eric M.
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PROTON therapy , *PROSTATE cancer patients , *RADIOTHERAPY , *DISEASE risk factors , *INTENSITY modulated radiotherapy - Abstract
Purpose: Data comparing moderately hypofractionated intensity modulated radiation therapy (IMRT) and proton beam therapy (PBT) are lacking. We aim to compare late toxicity profiles of patients with early-stage prostate cancer treated with moderately hypofractionated PBT and IMRT.Methods and Materials: This multi-institutional analysis included patients with low- or intermediate-risk biopsy-proven prostate adenocarcinoma from 7 tertiary referral centers treated from 1998 to 2018. All patients were treated with moderately hypofractionated radiation, defined as 250 to 300 cGy per daily fraction given for 4 to 6 weeks, and stratified by use of IMRT or PBT. Primary outcomes were late genitourinary (GU) and gastrointestinal (GI) toxicity. Adjusted toxicity rates were calculated using inverse probability of treatment weighting, accounting for race, National Comprehensive Cancer Network risk group, age, pretreatment International Prostate Symptom Score (GU only), and anticoagulant use (GI only).Results: A total of 1850 patients were included: 1282 IMRT (median follow-up 80.0 months) and 568 PBT (median follow-up 43.9 months). Overall toxicity rates were low, with the majority of patients experiencing no late GU (56.6%, n = 1048) or late GI (74.4%, n = 1377) toxicity. No difference was seen in the rates of late toxicity between the groups, with late grade 3+ GU toxicity of 2.0% versus 3.9% (odds ratio [OR] 0.47; 95% confidence interval 0.17-1.28) and late grade 2+ GI toxicity of 14.6% versus 4.7% (OR 2.69; confidence interval 0.80-9.05) for the PBT and IMRT cohorts, respectively. On multivariable analysis, no factors were significantly predictive of GU toxicity, and only anticoagulant use was significantly predictive of GI toxicity (OR 1.90; P = .008).Conclusions: In this large, multi-institutional analysis of 1850 patients with early-stage prostate cancer, treatment with moderately hypofractionated IMRT and PBT resulted in low rates of toxicity. No difference was seen in late GI and GU toxicity between the modalities during long-term follow-up. Both treatments are safe and well tolerated. [ABSTRACT FROM AUTHOR]- Published
- 2021
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5. Stigma, beliefs and perceptions regarding prostate cancer among Black and Latino men and women.
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Vapiwala, Neha, Miller, David, Laventure, Brenda, Woodhouse, Kristina, Kelly, Sheila, Avelis, Jade, Baffic, Cordelia, Goldston, Rodney, and Glanz, Karen
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HEALTH equity , *PROSTATE cancer , *AFRICAN Americans , *HISPANIC Americans , *ETHNIC groups - Abstract
Background: Health disparities in prostate cancer (PC) are thought to reflect the complex interplay of socioeconomics, environment and biology. The potential impact of beliefs and perceptions about PC among Black and Latino populations on clinical disparities are not well understood. This qualitative study was conducted to assess current prevalent and pervasive stigma, beliefs and perceptions regarding PC among Blacks and Latinos living in a large metropolitan area, thereby identifying potentially modifiable barriers to care.Methods: Qualitative data were collected through four separate focus groups of self-identified Black and Latino adult men and women living in Philadelphia to better understand their perceptions of PC diagnosis, screening and treatment. Each focus group was single-sex and conducted by racial/ethnic group in order to assess possible differences in beliefs about PC based on gender and racial/ethnic affiliation. Audio recordings were transcribed verbatim by trained research assistants and qualitative data analysis was conducted using modified grounded theory.Results: There were a total of 34 participants: 19 Hispanics/Latinos and 15 Blacks, with equal numbers of men and women (n=17). Median age was 57 years (range: 18 to 85 years). Dominant themes that emerged with respect to PC diagnosis included the stigma surrounding this condition and the perceived role of an "unhealthy lifestyle" and certain sexual behaviors as risk factors for PC development. While the majority of participants acknowledged the importance of PC screening and early detection, discussion centered around the barriers to both the interest in seeking medical care and the likelihood of securing it. These barriers included misunderstanding of PC etiology, distrust of the medical profession, and financial/access limitations. Men expressed substantial confusion about PC screening guidelines. In the Black female group, the role of faith and religion in the course of disease was a major theme. Both Black and Latina females discussed the role of fear and avoidance around PC screening and treatment, as well as the prevalence of misinformation about PC in their familial and social communities.Conclusion: Black and Latino focus groups revealed the existence of cultural beliefs, misunderstandings and fears pertaining to PC which could influence health-related behaviors. Some themes were common across groups; others suggested racial and gender predilections. Future targeted efforts focused on directly addressing prevalent misperceptions among underserved communities in urban settings could help to improve health literacy and equity in PC outcomes in these populations. [ABSTRACT FROM AUTHOR]- Published
- 2021
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6. US Radiation Oncologists (Re)Defined: An American Society for Radiation Oncology Scope of Practice Study.
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Fung, Claire Y., Vapiwala, Neha, Mattes, Malcolm D., Mohindra, Pranshu, Shah, Chirag, Yechieli, Raphael, Truong, Minh-Tam, Sanders, Tim, Arnone, Anna, Royce, Trevor J., and Ennis, Ronald D.
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ONCOLOGISTS , *CANCER treatment , *RADIATION , *KNOWLEDGE gap theory , *ONCOLOGY - Abstract
Purpose: To assess US radiation oncologists' views on practice scope and the ideal role of the radiation oncologist (RO), the American Society for Radiation Oncology (ASTRO) conducted a scope of practice survey.Methods and Materials: In spring 2019, ASTRO distributed an online survey to 3822 US RO members. The survey generated 984 complete responses (26% response rate) for analysis. Face validity testing confirmed respondents were representative of ASTRO's RO membership.Results: Nearly all respondents agreed that "ROs should be leaders in oncologic care." Respondents indicated the ideal approach to patient care was to provide "an independent opinion on radiation therapy and other treatment options" (82.5%) or "an independent opinion on radiation therapy but not outside of it" (16.1%), with only 1.4% favoring provision of "radiation therapy at the request of the referring physician" as the ideal approach. Actual practice fully matched the ideal approach in 18.2% of respondents. For the remaining majority, actual practice did not always match the ideal and comprised a mix of approaches that included providing radiation at the referring physician's request 24.0% of the time on average. Reasons for the mismatch included fear of alienating referring physicians and concern for offering an unwelcome opinion. One-fifth of respondents expressed a desire to expand the scope of service though interspecialty politics and insufficient training were potential barriers. Respondents interested in expanding scope of practice were on average earlier in their career (average years in practice 13.3) than those who were not interested (average years in practice 17.2, P < .001). Radiopharmaceuticals administration, medical marijuana and anticancer medications prescribing, and RO inpatient service represented areas of interest for expansion but also knowledge gaps.Conclusions: These results provide insight regarding US ROs' scope of practice and attitudes on the ideal role of the RO. For most ROs, to provide an independent opinion on treatment options represented the ideal approach to care, but barriers such as concern of alienating referring physicians prevented many from fully adhering to their ideal in practice. Actual practice commonly comprised a mixed approach, including the least favored scenario of delivering radiation at the referring physician's request one-quarter of the time, highlighting the influence of interspecialty politics on practice behavior. Advocacy for open communication and meaningful interdisciplinary collaboration presents an actionable solution toward a more balanced relationship with other specialties as ROs strive to better fulfill the vision of being leaders in oncologic care and being our best for our patients. The study also identified interest in expanding into nontraditional domains that offer opportunities to address unmet needs in the cancer patient's journey and elevate radiation oncology within the increasingly value-based US health care system. [ABSTRACT FROM AUTHOR]- Published
- 2021
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7. Trends in Utilization and Medicare Spending on Short-Course Radiation Therapy for Breast and Prostate Cancer: An Episode-Based Analysis From 2015 to 2019.
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Patel, Tej A., Jain, Bhav, Vapiwala, Neha, Chino, Fumiko, Tringale, Kathryn R., Mahal, Brandon A., Yamoah, Kosj, McBride, Sean N., Lam, Miranda B., Hubbard, Anne, Nguyen, Paul L., and Dee, Edward Christopher
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RADIOTHERAPY , *BREAST cancer , *MEDICARE , *LOGISTIC regression analysis , *ODDS ratio , *PROSTATE cancer , *HYPOPHARYNGEAL cancer - Abstract
Evidence supports the value of shorter, similarly efficacious, and potentially more cost-effective hypofractionated radiation therapy (RT) regimens in many clinical scenarios for breast cancer (BC) and prostate cancer (PC). However, practice patterns vary considerably. We used the most recent Centers for Medicare and Medicaid Services data to assess trends in RT cost and practice patterns among episodes of BC and PC. We performed a retrospective cohort analysis of all external beam RT episodes for BC and PC from 2015 to 2019 to assess predictors of short-course RT (SCRT) use and calculated spending differences. Multivariable logistic regression defined adjusted odds ratios of receipt of SCRT over longer-course RT (LCRT) by treatment modality, age, year of diagnosis, type of practice, and the interaction between year and treatment setting. Medicare spending was evaluated using multivariable linear regression controlling for duration of RT regimen (SCRT vs LCRT) in addition to the above covariables. Of 143,729 BC episodes and 114,214 PC episodes, 63,623 (44.27%) and 25,955 (22.72%) were SCRT regimens, respectively. Median total spending for SCRT regimens among BC episodes was $9418 (interquartile range [IQR], $7966-$10,983) versus $13,602 (IQR, $11,814-$15,499) for LCRT. Among PC episodes, median total spending was $6924 (IQR, $4,509-$12,905) for stereotactic body RT, $18,768 (IQR, $15,421-$20,740) for moderate hypofractionation, and $27,319 (IQR, $25,446-$29,421) for LCRT. On logistic regression, receipt of SCRT was associated with older age among both BC and PC episodes as well as treatment at hospital-affiliated over freestanding sites (P <.001 for all). In this evaluation of BC and PC RT episodes from 2015 to 2019, we found that shorter-course RT resulted in lower costs than longer-course RT. SCRT was also more common in hospital-affiliated sites. Future research focusing on potential payment incentives encouraging SCRT when clinically appropriate in the 2 most common cancers treated with RT will be valuable as the field continues to prospectively evaluate cost-effective hypofractionation in other disease sites. [ABSTRACT FROM AUTHOR]
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- 2024
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8. "Likely Pathogenic Heterozygous ATM Gene Mutation": Not Always What It Seems.
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Vapiwala, Neha and Maxwell, Kara N.
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GENETIC mutation , *AUTOMATED teller machines - Published
- 2024
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9. Enhancing Career Paths for Tomorrow's Radiation Oncologists.
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Vapiwala, Neha, Thomas, Charles R., Grover, Surbhi, Yap, Mei Ling, Mitin, Timur, Shulman, Lawrence N., Gospodarowicz, Mary K., Longo, John, Petereit, Daniel G., Ennis, Ronald D., Hayman, James A., Rodin, Danielle, Buchsbaum, Jeffrey C., Vikram, Bhadrasain, Abdel-Wahab, May, Epstein, Alan H., Okunieff, Paul, Goldwein, Joel, Kupelian, Patrick, and Weidhaas, Joanne B.
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RADIATION injuries , *RADIATION - Published
- 2019
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10. Pre-specialization – Considerations for more focused and personalized educational modules in the twenty-first century.
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Han, Jason J. and Vapiwala, Neha
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AUTONOMY (Psychology) , *CLINICAL medicine , *CURRICULUM planning , *EXPERIENCE , *HEALTH care teams , *LEARNING strategies , *MEDICAL schools , *MEDICAL education , *MEDICAL specialties & specialists , *PROFESSIONS , *SCHOOL environment , *SOCIAL psychology , *STUDENTS , *VOCATIONAL guidance , *EVIDENCE-based medicine , *PROFESSIONAL practice - Abstract
Background: This essay provides a multidisciplinary discussion of the current medical education curriculum and the increasing need to adapt it to our rapidly evolving and expanding healthcare environment. Methods: Thorough literature search on the topic of medical school curriculum, ranging from its historical origins to contemporary practice as well as statistics, was conducted. Results: The authors give a brief historical overview of and rationale behind the current structure of the medical education system in America. The recent trends towards information overload and rapid evolution of the evidence-base are discussed. Specialization, as a means of responding to the burgeoning abundance of information in medicine, is described. The authors further provide current as well as foreseeable limitations of today's medical training paradigm as the trend towards specialization continues. The potential negative influences of a specialist-focused training paradigm on the overall length of training and the degree of autonomy exercised by generalists are described. A proposal toward pre-specialization at the level of medical school is introduced and elaborated upon. The authors incorporate social psychology principles and analyze trends toward career specialization, highlighting potential benefits to a different-size-for-all approach. The importance of optionality and flexibility of such a curriculum is emphasized. Conclusions: The authors describe the inevitable trend toward specialization, and the need to fundamentally re-configure American medical education system to behoove trainees' experiences and quality of training during the 21st century. [ABSTRACT FROM AUTHOR]
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- 2019
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11. Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma: American Society of Clinical Oncology Endorsement of the American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline Summary.
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Quon, Harry, Vapiwala, Neha, Forastiere, Arlene, and Kennedy, Erin B.
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CISPLATIN , *FLUOROURACIL , *THERAPEUTIC use of monoclonal antibodies , *CARBOPLATIN , *MEDICAL protocols , *PAPILLOMAVIRUSES , *RADIOTHERAPY , *RISK assessment , *SQUAMOUS cell carcinoma , *OROPHARYNGEAL cancer , *CHEMORADIOTHERAPY , *THERAPEUTICS - Abstract
The article discusses a radiation therapy for oropharyngeal squamous cell carcinoma as guided by the guidelines issued by the American Society of Clinical Oncology and the American Society for Radiation Oncology. It mentions that the purpose of the guidelines is to formulate evidence-based practice for practitioners and that the ASTRO recommendations are listed in the Bottom Line Box.
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- 2018
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12. Care Provider or Service Provider: What Should the Role of Radiation Oncologists Be in the Future?
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Vapiwala, Neha, Shulman, Lawrence N., and Thomas Jr., Charles R.
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TUMOR diagnosis , *TUMOR treatment , *CANCER patient medical care , *IMMUNOTHERAPY , *ONCOLOGISTS , *MEDICAL radiology , *SERIAL publications , *TUMORS , *DECISION making in clinical medicine , *OCCUPATIONAL roles , *PATIENT-centered care , *INDIVIDUALIZED medicine - Abstract
An editorial is presented about the potential role of radiation oncologists (ROs) who could be functioned as service providers or as a care provider. Topics discussed include the engagement of the RO in patient management, their role in the creation and administration of innovative treatment strategies, as well in survivorship clinics, and the establishment of more RO-staffed inpatient services in the U.S.
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- 2018
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13. Advancing Our Practice Through the Advanced Practice Radiation Therapist Model: Catching Up With Canada.
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Vapiwala, Neha, Giuliani, Meredith, and Harnett, Nicole
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CANCER radiotherapy , *MEDICAL quality control , *CANCER prevention , *MEDICAL care - Published
- 2017
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14. No impact of breast magnetic resonance imaging on 15-year outcomes in patients with ductal carcinoma in situ or early-stage invasive breast cancer managed with breast conservation therapy.
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Vapiwala, Neha, Hwang, Wei‐Ting, Kushner, Carolyn J., Schnall, Mitchell D., Freedman, Gary M., and Solin, Lawrence J.
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BREAST cancer diagnosis , *LUMPECTOMY , *DUCTAL carcinoma , *MAGNETIC resonance imaging , *RADIOTHERAPY treatment planning , *CANCER treatment , *BREAST tumor diagnosis , *BREAST tumor treatment , *ADENOCARCINOMA , *ANTHROPOMETRY , *MAMMOGRAMS , *BREAST tumors , *COMBINED modality therapy , *LONGITUDINAL method , *METASTASIS , *PROGNOSIS , *RESEARCH funding , *TUMOR classification , *TREATMENT effectiveness , *DIAGNOSIS - Abstract
Background: For women undergoing breast conservation therapy (BCT), the added value of breast magnetic resonance imaging (MRI) at the time of initial diagnosis remains controversial. The current study was performed to determine long-term outcomes after BCT for women with and without pretreatment breast MRI.Methods: Between 1992 and 2001, a total of 755 women with ductal carcinoma in situ or early-stage invasive breast cancer underwent breast-conserving surgery (with axillary lymph node staging for invasive carcinoma) followed by definitive breast radiotherapy. Evaluation at the time of the initial diagnosis included conventional mammography in all subjects and breast MRI in 215 women (28%). Clinical, pathologic, and treatment characteristics were comparable for patients with and without breast MRI. Outcomes were determined using the Kaplan-Meier method and compared using the log-rank method.Results: At a median follow-up of 13.8 years, there were 49 local failures (15 women with and 34 women without breast MRI, respectively). The 15-year local failure rates were 8% for women with and 8% for women without MRI (P = .59). There also were no differences noted between women with and without breast MRI with regard to 15-year rates of overall survival (77% vs 71%; P = .24), freedom from distant metastases (86% vs 90%; P = .08), and contralateral breast cancer (10% vs 8%; P = .10). Multivariate analysis demonstrated no significant impact of breast MRI on local failure (P = .96).Conclusions: Breast MRI during the initial evaluation for BCT appears to have no significant impact on 15-year rates for local control, overall survival, freedom from distant metastases, or contralateral breast cancer. The routine use of pretreatment breast MRI is not indicated for patients undergoing BCT. Cancer 2017;123:1324-1332. © 2016 American Cancer Society. [ABSTRACT FROM AUTHOR]- Published
- 2017
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15. Phase 1 Trial of Everolimus and Radiation Therapy for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy.
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Narayan, Vivek, Vapiwala, Neha, Mick, Rosemarie, Subramanian, Pearl, Christodouleas, John P., Bekelman, Justin E., Deville, Curtiland, Rajendran, Ramji, and Haas, Naomi B.
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PROSTATE cancer treatment , *CANCER radiotherapy , *EVEROLIMUS , *CANCER relapse , *PROSTATECTOMY , *SALVAGE therapy , *PROSTATE-specific antigen , *THERAPEUTICS - Abstract
Purpose: In up to half of patients treated with salvage radiation therapy (SRT) for rising prostate-specific antigen levels, a second biochemical recurrence ultimately develops. Phosphatase and tensin homolog inactivation is implicated in prostate cancer progression, and upregulation of the mammalian target of rapamycin pathway can lead to tumor hypoxia and radioresistance. Everolimus is a mammalian target of rapamycin inhibitor with both antitumor and radiosensitizing effects.Methods and Materials: We performed a phase 1 study using a modified 3 + 3 dose-escalation design to evaluate the safety and tolerability of everolimus in combination with standard SRT for the treatment of biochemical recurrence following prostatectomy. After a 2-week run-in period of everolimus daily therapy, patients received prostate bed irradiation with daily cone beam computed tomography localization in 37 fractions of 1.8 Gy each (total dose, 66.6 Gy). Patients were monitored for both acute (≤90 days) and chronic (>90 days) treatment-related toxicities.Results: Eighteen patients received everolimus at dose levels of 5 mg (n=6), 7.5 mg (n=6), or 10 mg (n=6) daily in conjunction with SRT. No dose-limiting toxicities were observed. Common acute treatment-related toxicities included grade 1 or 2 mucositis (55.6%), grade 1 or 2 fatigue (38.9%), grade 1 or 2 rash (61.1%), and grade 1 urinary symptoms (61.1%). A grade 3 acute toxicity occurred in 4 patients (22.2%) (n=1 for rash, anemia, lymphopenia, and neutropenia), and no patients had a chronic toxicity of grade 3 or greater. After a median follow-up time of 17.8 months (range, 1.2-46.0 months), an undetectable prostate-specific antigen nadir was achieved in 9 patients (56.3%) and a second biochemical recurrence developed in 5 patients (31.3%).Conclusions: Everolimus at a dose of ≤10 mg daily appears to be safe and tolerable in combination with fractionated post-prostatectomy radiation therapy. [ABSTRACT FROM AUTHOR]- Published
- 2017
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16. Challenging assumptions of innateness – leave nothing unturned.
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Han, Jason J and Vapiwala, Neha
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CEREBRAL dominance , *DEVELOPMENTAL psychobiology , *INTUITION , *MEDICAL education , *PSYCHOANALYTIC interpretation , *SUBCONSCIOUSNESS , *JOB performance - Abstract
The authors describe the potential to enrich medical curricula by overthrowing assumptions that certain skills or characteristics are innate instead of requiring deliberate teaching. [ABSTRACT FROM AUTHOR]
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- 2019
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17. Taking "the Game" Out of The Match: A Simple Proposal.
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Wu, Abraham J., Vapiwala, Neha, Chmura, Steven J., Das, Prajnan, Decker, Roy H., Terezakis, Stephanie A., and Zietman, Anthony L.
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- 2015
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18. Association between hospital competition and quality of prostate cancer care.
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Jayadevappa, Ravishankar, Malkowicz, S. Bruce, Vapiwala, Neha, Guzzo, Thomas J., and Chhatre, Sumedha
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AFRICAN American men , *PROSTATE cancer , *CANCER treatment , *MORTALITY , *RACE , *AFRICAN Americans , *WATCHFUL waiting - Abstract
Background: Hospitals account for approximately 6% of United States' gross domestic product. We examined the association between hospital competition and outcomes in elderly with localized prostate cancer (PCa). We also assessed if race moderated this association. Methods: Retrospective study using Surveillance, Epidemiology, and End Results (SEER) – Medicare database. Cohort included fee-for-service, African American and white men aged ≥ 66, diagnosed with localized PCa between 1998 and 2011 and their claims between 1997 and 2016. We used Hirschman-Herfindahl index (HHI) to measure of hospital competition. Outcomes were emergency room (ER) visits, hospitalizations, Medicare expenditure and mortality assessed in acute survivorship phase (two years post-PCa diagnosis), and long-term mortality. We used Generalized Linear Models for analyzing expenditure, Poisson models for ER visits and hospitalizations, and Cox models for mortality. We used propensity score to minimize bias. Results: Among 253,176 patients, percent change in incident rate of ER visit was 17% higher for one unit increase in HHI (IRR: 1.17, 95% CI: 1.15–1.19). Incident rate of ER was 24% higher for whites and 48% higher for African Americans. For one unit increase in HHI, hazard of short-term all-cause mortality was 7% higher for whites and 11% lower for African Americans. The hazard of long-term all-cause mortality was 10% higher for whites and 13% higher for African Americans. Conclusions: Lower hospital competition was associated with impaired outcomes of localized PCa care. Magnitude of impairment was higher for African Americans, compared to whites. Future research will explore process through which competition affects outcomes and racial disparity. [ABSTRACT FROM AUTHOR]
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- 2023
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19. Popping the medical education bubble before it forms: It's about dollars and sense*.
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Grant, Ryan and Vapiwala, Neha
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MEDICAL education , *AUTONOMY (Psychology) , *PSYCHOLOGICAL burnout , *DEBT , *INCOME , *JOB satisfaction , *LABOR supply , *MEDICAL schools , *PHYSICIANS , *PROFESSIONS , *PROFESSIONAL standards , *ECONOMICS - Abstract
Headlines have previously acknowledged the risk of a "bubble and crash" phenomenon in the physician workforce pipeline. A growing number of medical career dissatisfiers, including emotional and physical burnout, loss of autonomy and burdensome regulations, compound the longstanding fundamental issue of the prohibitive direct and opportunity costs associated with medical training. For U.S. medical education and, in turn, healthcare to remain robust and high-quality, creative solutions are needed to address the untenable physician debt-to-income ratios and to ensure not only that the quantity and quality of medical school aspirants remains favorable to the profession, but that the profession remains responsible to its future members. Creating fiscally healthy physicians is a societal imperative. [ABSTRACT FROM AUTHOR]
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- 2018
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20. Radiation Oncology Resident In-Training Examination.
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Hatch, Sandra S., Vapiwala, Neha, Rosenthal, Seth A., Plastaras, John P., Blumberg, Albert L., Jr.Small, William, Wenger, Matthew J., and Taylor, Marie E.
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ONCOLOGY education , *CANCER radiotherapy , *KURTOSIS , *RADIOTHERAPY treatment planning - Published
- 2015
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21. Cultivating Tomorrow's Clinician Scientists: We Reap What We Sow.
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Vapiwala, Neha, Moghanaki, Drew, and Movsas, Benjamin
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- 2015
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22. Cultivating Tomorrow's Clinician Scientists: We Reap What We Sow.
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Vapiwala, Neha, Moghanaki, Drew, and Movsas, Benjamin
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CANCER radiotherapy , *MEDICAL school graduates , *BIOMEDICAL engineering , *PLASTIC surgery , *AMALGAMS (Alloys) , *INTELLECTUAL capital - Published
- 2015
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23. Continuity of care and advanced prostate cancer.
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Jayadevappa, Ravishankar, Guzzo, Thomas, Vapiwala, Neha, Malkowicz, Stanley Bruce, Gallo, Joseph J., and Chhatre, Sumedha
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CONTINUUM of care , *PROSTATE cancer , *MEDICARE , *RACE , *PRIMARY care , *AFRICAN Americans , *MEDICARE beneficiaries - Abstract
Background: Continuity of care is an important element of advanced prostate cancer care due to the availability of multiple treatment options, and associated toxicity. However, the association between continuity of care and outcomes across different racial groups remains unclear. Objective: To assess the association of provider continuity of care with outcomes among Medicare fee-for-service beneficiaries with advanced prostate cancer and its variation by race. Design: Retrospective cohort study using Surveillance, Epidemiology, and End Results (SEER)-Medicare data. Subjects: African American and white Medicare beneficiaries aged 66 or older, and diagnosed with advanced prostate cancer between 2000 and 2011. At least 5 years of follow-up data for the cohort was used. Measures: Short-term outcomes were emergency room (ER) visits, hospitalizations, and cost during acute survivorship phase (2-year post-diagnosis), and mortality (all-cause and prostate cancer-specific) during the follow-up period. We calculated continuity of care using Continuity of Care Index (COCI) and Usual Provider Care Index (UPCI), for all visits, oncology visits, and primary care visits in acute survivorship phase. We used Poisson models for ER visits and hospitalizations, and log-link GLM for cost. Cox model and Fine-Gray competing risk models were used for survival analysis, weighted by propensity score. We performed similar analysis for continuity of care in the 2-year period following acute survivorship phase. Results: One unit increase in COCI was associated with reduction in short-term ER visits (incidence rate ratio [IRR] = 0.65, 95% confidence interval [CI] 0.64, 0.67), hospitalizations (IRR = 0.65, 95% CI 0.64, 0.67), and cost (0.64, 95% CI 0.61, 0.66) and lower hazard of long-term mortality. Magnitude of these associations differed between African American and white patients. We observed comparable results for continuity of care in the follow-up period. Conclusions: Continuity of care was associated with improved outcomes. The benefits of higher continuity of care were greater for African Americans, compared to white patients. Advanced prostate cancer survivorship care must integrate appropriate strategies to promote continuity of care. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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24. The American Society for Radiation Oncology Workforce Statement.
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Shah, Chirag, Mohindra, Pranshu, Vapiwala, Neha, Campbell, Shauna, Bates, James Edward, Mattes, Malcolm D., Sim, Austin, Fontanilla, Hiral P., Fields, Emma, Pinnix, Chelsea C., and Haffty, Bruce
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LABOR supply , *ONCOLOGY , *RADIATION - Published
- 2023
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25. A Study to Quantify the Effectiveness of Daily Endorectal Balloon for Prostate Intrafraction Motion Management
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Wang, Ken Kang-Hsin, Vapiwala, Neha, Deville, Curtiland, Plastaras, John P., Scheuermann, Ryan, Lin, Haibo, Bar Ad, Voika, Tochner, Zelig, and Both, Stefan
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PROSTATE diseases , *RADIOTHERAPY , *QUANTITATIVE research , *MEDICAL statistics , *TREATMENT effectiveness , *MOTION analysis - Abstract
Purpose: To quantify intrafraction prostate motion between patient groups treated with and without daily endorectal balloon (ERB) employed during prostate radiotherapy and establish the effectiveness of the ERB. Methods: Real-time intrafraction prostate motion from 29 non-ERB (1,061 sessions) and 30 ERB (1,008 sessions) patients was evaluated based on three-dimensional (3D), left, right, cranial, caudal, anterior, and posterior displacements. The average percentage of time with 3D and unidirectional prostate displacements >2, 3, 4, 5, 6, 7, 8, 9, and 10 mm in 1-min intervals was calculated for up to 6 min of treatment time. The Kolmogorov-Smirnov method was used to evaluate the intrafraction prostate motion pattern between both groups. Results: Large 3D motion (up to 1 cm or more) was only observed in the non-ERB group. The motion increased as a function of elapsed time for displacements >2–8 mm for the non-ERB group and >2–4 mm for the ERB group (p < 0.05). The percentage time distributions between the two groups were significantly different for motion >5 mm (p < 0.05). The 3D symmetrical internal margin (IM) can be reduced from 5 to 3 mm (40% reduction), whereas the asymmetrical IM can be reduced from 3 to 2 mm (33% reduction) in cranial, caudal, anterior, and posterior for 6 min of treatment, when ERB is used. Beyond 6 min, the symmetrical 3D and asymmetrical cranial, caudal, anterior, and posterior IMs can be reduced from 9, 4, 7, 7, and 8 to 5, 2, 5, 3, and 4 mm, respectively (up to 57% reduction). Conclusion: The percentage of time that the prostate was displaced in any direction was less in the ERB group for almost all magnitudes of motion considered. The directional analysis shows that the ERB reduced IMs in almost all directions, especially the anterior-posterior direction. [ABSTRACT FROM AUTHOR]
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- 2012
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26. Comparative Toxicity and Dosimetric Profile of Whole-Pelvis Versus Prostate Bed-Only Intensity-Modulated Radiation Therapy After Prostatectomy
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Deville, Curtiland, Vapiwala, Neha, Hwang, Wei-Ting, Lin, Haibo, Bar Ad, Voichita, Tochner, Zelig, and Both, Stefan
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PELVIS cancer treatment , *CANCER radiotherapy , *TOXICITY testing , *RADIATION dosimetry , *PROSTATE-specific antigen , *REGRESSION analysis , *COMPARATIVE studies , *THERAPEUTICS ,PROSTATECTOMY complications - Abstract
Purpose: To assess whether whole-pelvis (WP) intensity modulated radiation therapy (IMRT) for prostate cancer (PCa) after prostatectomy is associated with increased toxicity compared to prostate-bed only (PB) IMRT. Methods and Materials: All patients (n = 67) undergoing postprostatectomy IMRT to 70.2 Gy at our institution from January 2006 to January 2009 with minimum 12-month follow-up were divided into WP (n = 36) and PB (n = 31) comparison groups. WP patients received initial pelvic nodal IMRT to 45 Gy. Pretreatment demographics, bladder and rectal dose-volume histograms, and maximum genitourinary (GU) and gastrointestinal (GI) toxicities were compared. Logistic regression models evaluated uni- and multivariate associations between pretreatment demographics and toxicities. Results: Pretreatment demographics including age and comorbidities were similar between groups. WP patients had higher Gleason scores, T stages, and preoperative prostate-specific antigen (PSA) levels, and more WP patients underwent androgen deprivation therapy (ADT). WP minimum (Dmin) and mean bladder doses, bladder volumes receiving more than 5 Gy (V5) and V20, rectal Dmin, and PB bladder and rectal V65 were significantly increased. Maximum acute GI toxicity was Grade 2 and was increased for WP (61%) vs. PB (29%) patients (p = 0.001); there was no significant difference in acute Grade ≥2 GU toxicity (22% WP vs. 10% PB; p = 0.193), late Grade ≥2 GI toxicity (3% WP vs. 0% PB; p = 0.678), or late Grade ≥2 GU toxicity (28% WP vs. 19% PB; p = 0.274) with 25-month median follow-up (range, 12–44 months). On multivariate analysis, long-term ADT use was associated with Grade ≥2 late GU toxicity (p = 0.02). Conclusion: Despite dosimetric differences in irradiated bowel, bladder, and rectum, WP IMRT resulted only in clinically significant increased acute GI toxicity in comparison to that with PB IMRT, with no differences in GU or late GI toxicity. [Copyright &y& Elsevier]
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- 2012
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27. Outcomes After Breast Conservation Treatment with Radiation in Women with Ductal Carcinoma In Situ and Prior Nonbreast Malignancy.
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Shah, Deepika N., Vapiwala, Neha, and Solin, Lawrence J.
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BREAST cancer treatment , *DUCTAL carcinoma , *CARCINOMA in situ , *CANCER-related mortality , *HEALTH outcome assessment , *CANCER radiotherapy - Abstract
Management of ductal carcinoma in situ (DCIS) of the breast is controversial, as not all patients progress to invasive carcinoma. This report analyzes the outcomes after breast conservation treatment (BCT) with radiation in patients with DCIS following prior malignancy at another anatomic site. The study cohort was comprised of 14 women with DCIS who were treated between 1978 and 2003. The median age at diagnosis of DCIS was 54 years (mean 56; range 37–78) and for the prior nonbreast malignancy was 44 years (mean 47; range 27–76). All patients underwent breast conservation surgery followed by whole breast radiation and tumor bed boost. The median and mean follow-up times after treatment of DCIS were 8.0 and 9.1 years, respectively (range 2–18). The median and mean interval period between the prior malignancy and DCIS was 6.0 and 8.2 years, respectively (range 1–30). There was one (7%) local failure, two (14%) contralateral breast cancers, and one (7%) death from breast cancer that occurred 7 years after BCT following contralateral invasive breast cancer. In this cohort of 14 patients treated for DCIS of the breast after a prior nonbreast malignancy, treatment for DCIS resulted in a high rate of local control and should be considered for curative intent. [ABSTRACT FROM AUTHOR]
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- 2009
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28. Regional Nodal Recurrence After Breast Conservation Treatment With Radiotherapy for Women With Early-Stage Breast Carcinoma
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Lukens, J. Nicholas, Vapiwala, Neha, Hwang, Wei-Ting, and Solin, Lawrence J.
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LYMPHATIC metastasis , *CANCER relapse , *BREAST cancer treatment , *CANCER radiotherapy , *WOMEN'S health , *PROGNOSIS - Abstract
Purpose: To report the long-term outcomes for women presenting with regional lymph node recurrence after breast conservation treatment with radiotherapy for Stage I and II invasive breast carcinoma. Methods and Materials: Of the women with pathologic Stage I and II invasive breast carcinoma treated with breast conservation treatment at the University of Pennsylvania, 29 developed regional nodal recurrence as their first site of failure. An analysis of the patterns of regional nodal recurrence and their prognosis after recurrence was undertaken. The median follow-up from regional nodal recurrence was 5.4 years. Results: The pattern of regional nodal recurrence was as follows: 14 (48%) with simultaneous local and axillary recurrence, 7 (24%) with recurrence in the axilla only, 5 (17%) with recurrence in the supraclavicular region only, and 3 (10%) with multiple nodal sites of recurrence. For the entire study group, the 5-, 10-, and 15-year overall survival rate was 70%, 37%, and 28%, respectively. The 10-year overall survival rate for patients with locoregional recurrence was 32% compared with 45% for patients with regional-only recurrence (p = 0.50). The 10-year overall survival rate for patients with axillary recurrence discovered on pathologic examination of the mastectomy specimen was 31% compared with 42% for patients with palpable regional lymphadenopathy (p = 0.83). Conclusion: Patients with regional nodal recurrence after breast conservation treatment with radiotherapy for early-stage breast carcinoma are potentially salvageable. The prognosis after regional nodal recurrence was not significantly different when stratified by the presence or absence of simultaneous in-breast recurrence or the method of detection. [Copyright &y& Elsevier]
- Published
- 2009
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29. Outcomes After Breast Conservation Treatment With Radiation in Women With Prior Nonbreast Malignancy and Subsequent Invasive Breast Carcinoma
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Nemani, Deepika, Vapiwala, Neha, Hwang, Wei-Ting, and Solin, Lawrence J.
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HEALTH outcome assessment , *BREAST cancer treatment , *CANCER radiotherapy , *BREAST cancer surgery , *CANCER invasiveness , *BREAST cancer patients , *COHORT analysis - Abstract
Purpose: Little information has been reported regarding outcomes after treatment for patients with early-stage invasive breast cancer and a prior nonbreast malignancy. This report analyzes the outcomes in patients with Stage I and II breast cancer after breast conservation treatment (BCT) with a prior nonbreast malignancy. Methods and Materials: The study cohort comprised 66 women with invasive breast cancer and a prior nonbreast malignancy. All patients were treated with breast conservation surgery followed by definitive breast irradiation between 1978 and 2003. Median ages at diagnosis of invasive breast cancer and prior malignancy were 57 and 50 years, respectively. The median interval between the prior malignancy and breast cancer was 7.0 years. Median and mean follow-up times after BCT were 5.3 and 7.0 years. Results: The 5-year and 10-year overall survival rates were 94% (95% confidence interval [CI], 82–98%) and 78% (95% CI, 59–89%), respectively. There were 4 patients (6%) with local failure and 10 patients (15%) with distant metastases. The 10-year rate of local failure rate was 5% (95% CI, 2–16%) and freedom from distant metastases was 78% (95% CI, 61–88%). No obvious differences in survival or local control were noted compared with the reported results in the literature for patients with invasive breast cancer alone. Conclusions: Both overall survival and local control at 5 and 10 years were comparable to rates observed in early-stage breast cancer patients without a prior malignancy. Prior nonbreast malignancy is not a contraindication to BCT, if the primary cancer is effectively controlled. [Copyright &y& Elsevier]
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- 2009
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30. Internet-Based Survey Evaluating Use of Pain Medications and Attitudes of Radiation Oncology Patients Toward Pain Intervention
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Simone, Charles B., Vapiwala, Neha, Hampshire, Margaret K., and Metz, James M.
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CANCER patients , *PAIN management , *ONCOLOGY , *PAIN medicine - Abstract
Purpose: Pain is a common symptom among cancer patients, yet many patients do not receive adequate pain management. Few data exist quantifying analgesic use by radiation oncology patients. This study evaluated the causes of pain in cancer patients and investigated the reasons patients fail to receive optimal analgesic therapy. Methods and Materials: An institutional review board-approved, Internet-based questionnaire assessing analgesic use and pain control was posted on the OncoLink (available at www.oncolink.org) Website. Between November 2005 and April 2006, 243 patients responded. They were predominantly women (73%), white (71%), and educated beyond high school (67%) and had breast (38%), lung (6%), or ovarian (6%) cancer. This analysis evaluated the 106 patients (44%) who underwent radiotherapy. Results: Of the 106 patients, 58% reported pain from their cancer treatment, and 46% reported pain directly from their cancer. The pain was chronic in 51% and intermittent in 33%. Most (80%) did not use medication to manage their pain. Analgesic use was significantly less in patients with greater education levels (11% vs. 36%, p = 0.002), with a trend toward lower use by whites (16% vs. 32%, p = 0.082) and women (17% vs. 29%, p = 0.178). The reasons for not taking analgesics included healthcare provider not recommending medication (87%), fear of addiction or dependence (79%), and inability to pay (79%). Participants experiencing pain, but not taking analgesics, pursued alternative therapies for relief. Conclusions: Many radiation oncology patients experience pain from their disease and cancer treatment. Most study participants did not use analgesics because of concerns of addiction, cost, or failure of the radiation oncologist to recommend medication. Healthcare providers should have open discussions with their patients regarding pain symptoms and treatment. [Copyright &y& Elsevier]
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- 2008
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31. Biopsy Findings After Breast Conservation Therapy for Early-Stage Invasive Breast Cancer
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Vapiwala, Neha, Starzyk, Jill, Harris, Eleanor E., Tchou, Julia C., Boraas, Marcia C., Czerniecki, Brian J., Rosato, Ernest F., Orel, Susan G., and Solin, Lawrence J.
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BIOPSY , *BREAST cancer , *CANCER in women , *CLINICAL pathology - Abstract
Purpose: To determine the patterns and factors predictive of positive ipsilateral breast biopsy after conservation therapy for early-stage breast cancer. Methods and Materials: We performed a retrospective review of Stage I-II breast cancer patients initially treated with lumpectomy and radiotherapy between 1977 and 1996, who later underwent post-treatment ipsilateral breast biopsies. Results: A total of 223 biopsies were performed in 193 treated breasts: 171 single and 22 multiple biopsies. Of the 223 biopsies, 56% were positive and 44% were negative for recurrence. The positive biopsy rate (PBR) was 59% for the first and 32% for subsequent biopsies. The median time to the first post-treatment biopsy was 49 months. Of the patients with negative initial biopsy findings, 11% later developed local recurrence. The PBR was 40% among patients with physical examination findings only, 65% with mammographic abnormalities only, and 79% with both findings (p = 0.001). Analysis of the procedure type revealed a PBR of 86% for core and 58% for excisional biopsies compared with 28% for aspiration cytology alone (p = 0.025). The PBR varied inversely with age at the original diagnosis: 49% if ≥51 years, 57% if 36–50 years, and 83% if ≤35 years (p = 0.05). The PBR correlated directly with the interval after radiotherapy: 49% if ≤60 months, 59% if 60.1–120 months, 77% if 120.1–180 months, and 100% if >180 months after completing postlumpectomy radiotherapy (p = 0.01). The PBR was not linked with recurrence location, initial pathologic T or N stage, estrogen receptor/progesterone receptor status, or final pathologic margins (all p ≥ 0.15). Conclusion: After definitive radiotherapy for early-stage breast cancer, a greater PBR was associated with the presence of both mammographic and clinical abnormalities, excisional or core biopsies, younger age at the initial diagnosis, and longer intervals after radiotherapy completion. [Copyright &y& Elsevier]
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- 2007
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32. Recent Trends in "Manels" and Gender Representation Among Panelists at North American Annual Radiation Oncology Meetings.
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Burgess, Laura, Ghosh, Anushka, Yeap, Beow Y., Rasheed, Nabeel, Ragala, Siri, Nwiloh, Anita, Willers, Henning, Zietman, Anthony, Vapiwala, Neha, and Kamran, Sophia C.
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MEDICAL school graduates , *GENDER inequality , *ONLINE education , *UNIVERSITY faculty , *ACADEMIC conferences - Abstract
Achieving gender equity in radiation oncology is an important goal, as a smaller proportion of women enter radiation oncology residency compared with those graduating from medical school. As invited speaking opportunities at academic medical conferences are vital for promotion/tenure, we investigated the prevalence of all-men panels ("manels") at American Society for Radiation Oncology (ASTRO) and Canadian Society of Radiation Oncology (CARO) annual meetings. Using ASTRO and CARO online meeting programs, 2018 to 2021 faculty information was obtained, including gender, panel role (chair vs nonchair), type of session, and topic. Primary outcomes included percentage of manels and proportion of female panelists over time. Representation of women among chairs was also evaluated. Over the 4-year study period across both conferences, a total of 765 panel sessions were held with 2973 faculty members, of whom 1287 (43.3%) were women. Of these sessions, 127 of 765 (16.6%) were manels. ASTRO meetings had 1169 of 2742 (42.6%) female faculty members and held 107 of 680 (15.7%) manels, whereas CARO meetings had 118 of 231 (51.1%) female faculty and held 20 of 85 manels (23.5%). From 2018 to 2021, the proportion of manels decreased at ASTRO and CARO meetings from 25.6% to 8.2% (P <.001) and from 29.6% to 15.0% (P =.130), respectively. The role of chair was majority male in every year from 2018 to 2021 at ASTRO meetings (58.6% overall), but more balanced at CARO meetings (48.0% overall). Among session types, the highest proportion of manels was observed for scientific sessions (19.1%, P =.011) at ASTRO meetings and leadership sessions (29.4%, P =.533) at CARO meetings. The lowest proportion of female panelists was on genitourinary cancer topics at ASTRO meetings (31.9%, P =.018) and physics topics at CARO meetings (40.4%, P =.085). During the study period, the proportion of female panelists increased with a corresponding decrease in manels. ASTRO and CARO should strive for further involvement of women and the elimination of manels whenever possible. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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33. Fighting prostate cancer with radium-223--not your Madame's isotope.
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Vapiwala, Neha and Glatstein, Eli
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RADIUMTHERAPY , *BONE tumors , *PROSTATE tumors - Published
- 2013
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34. Fighting Prostate Cancer with Radium-223 -- Not Your Madame's Isotope.
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Vapiwala, Neha and Glatstein, Eli
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RADIUMTHERAPY , *PROSTATE cancer , *PROSTATE cancer treatment , *DRUG efficacy , *DRUG approval , *PATIENT safety - Abstract
The authors reflect on the study by Parker and colleagues examining the efficacy of radium-223 dichloride (radium-223) in prostate cancer treatment. They mention that radium-2223 is considered to be the first emitter which undergo phase three testing and receive approval for clinical use. They state that the study of Parker and colleagues has remarkable tolerability of radium-23 in terms of patient's safety.
- Published
- 2013
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35. In Reply to Jenelle and Chang.
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Vapiwala, Neha
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CANCER radiotherapy , *PHYSIOLOGICAL effects of radiation , *MEDICAL radiology , *HEALTH programs , *MEDICAL communication - Published
- 2017
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36. Residency Match Interviews: Walking the Line Requires Knowing the Line.
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Vapiwala, Neha
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RESIDENTS (Medicine) , *INTERVIEWING , *MEDICAL care , *EMPLOYEE selection , *INTERNSHIP programs , *ONCOLOGY , *RADIOTHERAPY - Published
- 2017
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37. Declining Medical Student Interest in Radiation Oncology: Wake-Up Call With a Silver Lining?
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Brower, Jeffrey V., Blitzer, Grace C., Vapiwala, Neha, and Harari, Paul M.
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STUDENT interests , *ONCOLOGY , *RADIATION - Published
- 2021
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38. In Reply to Mell.
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Vapiwala, Neha, Moghanaki, Drew, and Movsas, Benjamin
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CANCER radiotherapy , *CANCER research , *CANCER hospitals , *MEDICAL physics - Published
- 2015
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39. The American Society for Radiation Oncology 2017 Radiation Oncologist Workforce Study.
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Fung, Claire Y., Chen, Erli, Vapiwala, Neha, Pohar, Surjeet, Trifiletti, Daniel, Truong, Minh-Tam, Uschold, George, Schuster, Jessica, Patel, Akshar, Jani, Ashesh, Mohindra, Pranshu, Sanders, Tim, Gardner, Liz, Arnone, Anna, and Royce, Trevor
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MANAGEMENT of electronic health records , *JOB vacancies , *RADIOTHERAPY , *ELECTRONIC health records , *CONE beam computed tomography - Abstract
Purpose: The aim of this study is to report the American Society for Radiation Oncology 2017 radiation oncologist (RO) workforce survey results; identify demographic, technology utilization, and employment trends; and assess the profession's ability to meet patients' needs, offer job satisfaction, and attract high-caliber trainees.Methods: In spring 2017, the American Society for Radiation Oncology distributed an online survey to 3856 US RO members. The questionnaire was patterned after the 2012 workforce survey for trend analysis. The 31% response rate yielded 1174 individual responses (726 practices) for analysis.Results: ROs' mean age was 50.9 years. Compared to 2012, female representation (28.9%) increased and white representation (69.8%) dropped. The proportion in rural practice (12.6%) decreased, whereas the number of suburban ROs (40.6%) increased and urban ROs (46.8%) remained high. Most ROs worked full-time, averaging 51.4 h/wk. Stereotactic body radiation therapy, cone beam computed tomography, and magnetic resonance/positron emission tomography-computed tomography fusion utilization increased, whereas low-dose-rate brachytherapy decreased by >15 percentage points. Hypofractionation utilization was 95.3% and was highest in academic/university systems and lowest in private solo practices (P < .001). More respondents were concerned about an RO oversupply rather than shortage. ROs reported 250 consults (median) and 20 on-treatment patients (median) in 2016 and greater time allocation to electronic health record management compared with 3 years earlier. Approximately 15% of ROs reported job vacancies, which were more prevalent in urban practices and academic/university systems. ROs were employed by academic/university systems, private practices, and nonacademic hospitals in a respective ratio of 2:2:1. Comparison with 2012 survey findings showed a shift from private practice toward academic/university systems and nonacademic hospitals. Compensation was predominantly productivity-based at private practices and a fixed salary or a base salary at academic/university systems and nonacademic hospitals. Practice merger/buyout was the lead reason for ROs to change employers.Conclusions: Since 2012, race and gender gaps narrowed, but geographic disparities persisted, with ROs gravitating toward resource-rich suburban and urban locations over rural practices. The workforce has shifted from predominantly private practice to more equal balance with academic/university systems. These findings reflect the current US RO landscape and serve to underscore the need for collective action to ensure equitable RO care for all patients. [ABSTRACT FROM AUTHOR]- Published
- 2019
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40. An Environmental Scan of Advanced Practice Radiation Therapy in the United States: A PESTEL Analysis.
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McDonagh, Danielle, Tonning, Kristi Linnea, Freeman, Brian, Birring, Eva J., Dimopoulos, Maria, Harnett, Nicole, Skubish, Samantha, Starrs, Clodagh, Mei, Sharon Wong Mei, Vapiwala, Neha, and Matthews, Kristie
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PEST analysis , *NURSE practitioners , *RADIOTHERAPY , *PHYSICIANS' assistants , *MEDICAL practice , *NURSES' aides , *MEDICAL care - Abstract
In 2021, the Advanced Practice Radiation Therapy Working Group (APRTWG) was established in the United States as a grassroots alliance of multidisciplinary radiation oncology professionals—radiation therapists, physicians, dosimetrists, and administrators—located across the country, interested in studying and establishing the Advanced Practice Radiation Therapist (APRT) level of practice in the United States. The APRT model has shown success in the United Kingdom, Canada, Australia, Singapore, and other countries, documenting the value of the APRT to the quality and advancement of clinical care. In the United States, the APRTWG seeks to coordinate activities, align resources, and drive the national agenda to collectively develop and define novel models of care using APRT in line with the evolving needs of patients and the radiation therapy profession. This environmental scan aims to examine the context of radiation oncology medical practice in the United States to inform pathways ahead for a proposed APRT model through a Political, Economic, Social, Technological, Environmental, and Legal (PESTEL) analysis. A literature search was conducted to understand the chronological timeline of the development of APRT during the past 25 years. Items that included the activities, scope of practice, and implementation of APRT nationally and internationally were identified. Papers describing advanced practitioner roles that are commonly found in the multidisciplinary team in radiation oncology both in the United States and internationally, such as physician assistants and nurse practitioners, were excluded. Despite the environmental scan outcome, it is acknowledged that data collation and analysis was not as robust as that anticipated by undertaking a systematic review. Papers were identified by the lead author that aligned with each of the PESTEL factors. Defined broadly, a new care model can adjust how health services are delivered by incorporating best practices in patient care for a specific population, person, or patient cohort. As patients enter different stages of their disease, the purpose of a new model is to provide individuals with the right care, at the right time, by the right team, in the right place. It is clear that the opportunity for positive change and impact on the current state of practice in radiation oncology exists. The environmental scan findings demonstrate the complexities associated with implementing APRT in the United States, with multifactorial political, environmental, societal, technological, economic, and legal aspects to consider. The APRTWG will continue to lead and participate in such activities to demonstrate and identify APRT role opportunities in the United States and drive the nationwide implementation of the APRT level of practice in this country. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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41. No Talent Left Behind: A Silver Lining for Diversity in Radiation Oncology in the Post-Coronavirus Disease 2019 (COVID-19) Era.
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Kamran, Sophia C, Yerramilli, Divya, and Vapiwala, Neha
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- 2020
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42. Caveat Emptor: Fellowship Training in Radiation Oncology; What, But More Importantly, Why?
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Wallner, Paul E., Rosenzweig, Kenneth E., and Vapiwala, Neha
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ONCOLOGISTS , *SCHOLARSHIPS , *RADIATION , *ONCOLOGY , *POSTDOCTORAL programs , *RADIOTHERAPY - Published
- 2020
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43. The state of survivorship care in radiation oncology: Results from a nationally distributed survey.
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Frick, Melissa A., Rosenthal, Seth A., Vapiwala, Neha, Monzon, Brian T., and Berman, Abigail T.
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CANCER patients , *ONCOLOGY , *CANCER relapse , *SURVIVAL analysis (Biometry) , *MEDICAL care - Abstract
Background: Survivorship care has become an increasingly critical component of oncologic care as well as a quality practice and reimbursement metric. To the authors' knowledge, the current climate of survivorship medicine in radiation oncology has not been investigated fully.Methods: An institutional review board-approved, Internet-based survey examining practices and preparedness in survivorship care was distributed to radiation oncology practices participating in the American College of Radiology Radiation Oncology Practice Accreditation program between November 2016 and January 2017. A total of 78 surveys were completed. Among these, 2 were nonphysicians, resulting in 76 evaluable responses.Results: Radiation oncologists (ROs) frequently reported that they are the primary provider in the evaluation of late toxicities and the recurrence of primary cancer. Although approximately 68% of ROs frequently discuss plans for future care with survivors, few provide a written survivorship care plan to their patients (18%) or the patients' primary care providers (24%). Patient prognosis, disease site, and reimbursement factors often influence the provision of survivorship care. Although ROs report that several platforms offer training in survivorship medicine, the quality of these resources is variable and extensive instruction is rare. Fewer than one-half of ROs believe they are expertly trained in survivorship care.Conclusions: ROs play an active role within the multidisciplinary team in the cancer-related follow-up care of survivors. Investigation of barriers to the provision of survivorship care and optimization of service delivery should be pursued further. The development of high-quality, easily accessible educational programming is needed so that ROs can participate more effectively in the care of cancer survivors. Cancer 2018;124:2653-60. © 2018 American Cancer Society. [ABSTRACT FROM AUTHOR]- Published
- 2018
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44. The American Society for Radiation Oncology Workforce Taskforce Review of the United States Radiation Oncology Workforce Analysis.
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Shah, Chirag, Mohindra, Pranshu, Arnone, Anna, Bates, James Edward, Mattes, Malcolm D., Campbell, Shauna, Fontanilla, Hiral P., Sim, Austin J., Sharp, Hadley J., Kelly, Patrick, Mantz, Constantine, Eichler, Thomas, Sandler, Howard, Fields, Emma, Pinnix, Chelsea C., Vapiwala, Neha, and Haffty, Bruce
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STEREOTACTIC radiotherapy , *LABOR supply , *SUPPLY & demand , *RADIATION - Abstract
Over the past decade, concerns have arisen in radiation oncology regarding potential workforce supply and demand imbalance. The American Society for Radiation Oncology commissioned an independent analysis in 2022, looking at supply and demand in the United States radiation oncology workforce and projecting future trends for 2025 and 2030. The final report, titled Projected Supply and Demand for Radiation Oncologists in the U.S. in 2025 and 2030, is now available. The analysis included evaluating radiation oncologist (RO) supply (new graduates, exits from the specialty), potential changes in demand (growth of Medicare beneficiaries, hypofractionation, loss of indications, new indications) as well as RO productivity (growth of work relative value units [wRVUs] produced), and demand per beneficiary. The results demonstrated a relative balance between radiation oncology supply and demand for radiation services; the growth in ROs was balanced by the rapid growth of Medicare beneficiaries over the same period. The primary factors driving the model were found to be growth of Medicare beneficiaries and change in wRVU productivity, with hypofractionation and loss of indication having only a moderate effect; although the most likely scenario was a balance of workforce supply and demand, scenarios did demonstrate the possibility of over- and undersupply. Oversupply may become a concern if RO wRVU productivity reaches the highest region; beyond 2030, this is also possible if growth in RO supply does not parallel Medicare beneficiary growth, which is projected to decline and will require corresponding supply adjustment. Limitations of the analysis included uncertainty regarding the true number of ROs, the lack of inclusion of most technical reimbursement and its effect as well as failing to account for stereotactic body radiation therapy. A modeling tool is available to allow individuals to evaluate different scenarios. Moving forward, continued study will be needed to evaluate trends (particularly wRVU productivity and Medicare beneficiary growth) to allow for continued assessment of workforce supply and demand in radiation oncology. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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45. Radiation Oncology Residency Training Program Integration of Diversity, Equity, and Inclusion: An Association of Residents in Radiation Oncology Equity and Inclusion Subcommittee Inaugural Program Director Survey.
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Williams, Vonetta M., Franco, Idalid, Tye, Karen E., Jagsi, Reshma, Sim, Austin J., Oladeru, Oluwadamilola T., Rivera, Amanda, Toumbou, Kadiata, Suneja, Gita, Deville, Curtiland, Siker, Malika L., Halasz, Lia M., Balogun, Onyinye D., Vapiwala, Neha, and Elmore, Shekinah N.C.
- Subjects
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CULTURAL pluralism , *CORPORATE culture , *RACE discrimination , *RACE , *MEDICAL incident reports - Abstract
The aim of this study was to investigate United States (US) radiation oncology (RO) program directors' (PDs) attitudes and practices regarding racial/ethnic diversity, equity, and inclusion (DEI) to better understand potential effects on underrepresented in medicine (UIM) residents in RO. A 28-item survey was developed using the validated Ethnic Harassment Experiences Scale and the Daily Life Experiences subscale, as well as input from DEI leaders in RO. The survey was institutional review board–approved and administered to RO PDs. PDs were provided with the American Association of Medical Colleges definition of UIM, that is, "Underrepresented in medicine means those racial and ethnic populations that are underrepresented in the medical profession relative to their numbers in the general population." Descriptive statistics were used in analysis. The response rate was 71% (64/90). Institutional Culture and Beliefs: 42% responded that they had a department DEI director. A minority (17%, n = 11) agreed "I believe that people from UIM backgrounds have equal access to quality tertiary education in the US." The majority (97%, n = 62) agreed "My program values residents from UIM backgrounds." Support and Resources: The majority (78%, n = 50) agreed "My program has resources in place to assist/provide support for resident physicians from UIM backgrounds." Interview and Recruitment: Most PDs (53%) had not taken part in activities aimed at recruiting UIM residents and 17% had interviewed no UIM applicants in the past 5 years for residency. Resident Experiences of Racism: 17% (n = 11) agreed "UIM residents in my program have reported incidents of racism to me," and 28% (n = 18) agreed "I believe that UIM residents in my program have been treated differently because of their race/ethnicity by faculty, staff, coresidents or patients." Most PDs reported that they did not believe that UIM residents were treated differently in their department because of their race/ethnicity, and only a minority had received reports of racial discrimination experienced by residents. These data contrast resident experiences and suggest a disconnect between DEI perceptions and resident experiences among US RO PDs that should be addressed through increased programmatic action and evaluation. [ABSTRACT FROM AUTHOR]
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- 2023
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46. Using Holistic Residency Applicant Review and Selection in Radiation Oncology to Enhance Diversity and Inclusion—An ASTRO SCAROP-ADROP-ARRO Collaboration.
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Jimenez, Rachel B., Pinnix, Chelsea C., Juang, Titania, Franco, Idalid, Sim, Austin J., Siker, Malika, Vapiwala, Neha, Chino, Fumiko, Shinohara, Eric T., Metz, James, Winkfield, Karen M., Suneja, Gita, Deville, Curtiland, and Gibbs, Iris C.
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RESIDENTS (Medicine) , *CULTURAL pluralism , *GRADUATE medical education , *ONCOLOGY , *RADIATION - Abstract
Disproportionate sex, racial, and ethnic diversity remains in the radiation oncology physician workforce despite widespread awareness and longitudinal efforts to improve representation. In this collaborative review, we define the rationale and components of holistic review and how it can be best used to provide a comprehensive evaluation of applicants to residency programs in radiation oncology. We initially discuss the current state of diversity in the field of radiation oncology and highlight the components of the residency selection process that may serve to perpetuate existing biases. Subsequently, the Accreditation Council for Graduate Medical Education and Association of American Medical Colleges holistic review framework is reviewed in detail to demonstrate the balanced assessment of potential applicants. The implementation of holistic review in medical school and residency selection to date is examined to underscore the potential value of holistic review in the radiation oncology residency selection process. Finally, recommendations for the practical implementation of holistic review in radiation oncology trainee selection are outlined. [ABSTRACT FROM AUTHOR]
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- 2023
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- View/download PDF
47. Radiation Oncology Resident Perspectives on Diversity, Equity, and Inclusion: An Association of Residents in Radiation Oncology Equity and Inclusion Subcommittee Inaugural Resident Survey.
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Williams, Vonetta M., Franco, Idalid, Tye, Karen E., Jagsi, Reshma, Sim, Austin J., Oladeru, Oluwadamilola T., Rivera, Amanda, Toumbou, Kadiata, Suneja, Gita, Deville, Curtiland, Siker, Malika L., Halasz, Lia M., Balogun, Onyinye D., Vapiwala, Neha, and Elmore, Shekinah N.C.
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FACULTY advisors , *CORPORATE culture , *BLACK people , *RACE , *ONCOLOGY - Abstract
In this study, radiation oncology residents were surveyed on perceptions of diversity, equity, inclusion, and belonging in their residency training programs. A 23-item survey was developed by the Association of Residents in Radiation Oncology Equity and Inclusion Subcommittee resident members and faculty advisors. The survey was divided into 4 sections: institutional culture, support and resources, interview and recruitment, and experiences of bias. The survey was sent individually to residents from all Accreditation Council for Graduate Medical Education–accredited radiation oncology programs. The survey was issued to 757 residents. A total of 319 residents completed the survey, for a response rate of 42%. All postgraduate years and geographic regions were represented. Significant racial, ethnic, and gender differences were present in survey response patterns. White residents (94%, 164 of 174) and male residents (96%, 186 of 194) were more likely to strongly agree/agree that they were treated with respect by their colleagues and their coworkers than other racial groups (P <.005) or gender groups (P <.008). Only 3% (5 of 174) of White residents strongly agreed/agreed that they were treated unfairly because of their race/ethnicity, while 31% (5 of 16) of Black residents and 10% (9 of 94) of Asian residents strongly agreed/agreed (P <.0001). Similarly, Hispanic residents were more likely to strongly agree/agree (24%, 5 of 21) than non-Hispanic residents (7%, 20 of 298) (P =.003). Regarding mentorship, there were no differences by gender or ethnicity. There were differences by race in residents reporting that they had a supportive mentor (P =.022), with 89% (154 of 174) of White residents who strongly agreed/agreed, 88% (14 of 16) of Black residents, and 91% of Asian residents (86 of 94). This survey reveals that experiences of support, mentorship, inclusion, and bias vary significantly among radiation oncology residents based on race, ethnicity, and gender. Radiation oncology has opportunity for growth to ensure an equitable experience for all residents. [ABSTRACT FROM AUTHOR]
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- 2023
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48. Radium-223 in prostate cancer.
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Vapiwala, Neha and Glatstein, Eli
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- 2013
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49. Applying lessons from social psychology to transform the culture of error disclosure.
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Han, Jason, LaMarra, Denise, and Vapiwala, Neha
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MEDICAL errors , *ORGANIZATIONAL learning , *SOCIAL psychology , *DISCLOSURE , *PATIENT satisfaction , *PHYSICIANS' attitudes , *CULTURE - Abstract
Context The ability to carry out prompt and effective error disclosure has been described in the literature as an essential skill among physicians that can lead to improved patient satisfaction, staff well-being and hospital outcomes. However, few studies have addressed the social psychology principles that may influence physician behaviour. Methods The authors provide an overview of recent administrative measures designed to encourage physicians to disclose error, but note that deliberate practice, buttressed with lessons from social psychology, is needed to implement further productive behavioural changes. Results Two main cognitive biases that may hinder error disclosure are identified, namely: fundamental attribution error, and forecasting error. Strategies to overcome these maladaptive cognitive patterns are discussed. The authors note that interactions with standardised patients (SPs) can be used to simulate hospital encounters and help teach important behavioural considerations. Virtual reality is introduced as an immersive, realistic and easily scalable technology that can supplement traditional curricula. Lastly, the authors highlight the importance of establishing a professional standard of competence, potentially by incorporating difficult patient encounters, including disclosure of error, into medical licensing examinations that assess clinical skills. Conclusions Existing curricula that cover physician error disclosure may benefit from reviewing the social psychology literature. These lessons, incorporated into SP programmes and emerging technological platforms, may improve training and evaluative methods for all medical trainees. [ABSTRACT FROM AUTHOR]
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- 2017
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50. Development of a United States Radiation Oncology Curricular Framework: A Stakeholder Delphi Consensus.
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Jeans, Elizabeth B., Brower, Jeffrey V., Burmeister, Jay W., Deville, Curtiland, Fields, Emma, Kavanagh, Brian D., Suh, John H., Tekian, Ara, Vapiwala, Neha, Zeman, Elaine M., and Golden, Daniel W.
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DELPHI method , *TRAINING of medical residents , *MEDICAL education examinations , *GRADUATE medical education , *REQUIRED courses (Education) , *ONCOLOGY - Abstract
A United States (US) radiation oncology curriculum, developed using best practices for curriculum inquiry, is needed to guide residency education and qualifying examinations. Competency-based training, including entrustable professional activities (EPAs), provides an outcomes-based approach to modern graduate medical education. This study aimed to define US radiation oncology EPAs and curricular content domains using a deliberative process with input from multiple stakeholder groups. The Radiation Oncology Education Collaborative Study Group Core Curriculum Project Leadership Committee developed initial content domains and EPAs. Following recruitment of stakeholders, a Delphi process was used to achieve consensus. In the first round, content domains and EPAs were reviewed for inclusion and exclusion, clarity, time allocation (content domains), and level of training (EPAs). Participants submitted additional content domains and EPAs for consideration. Any content domains or EPAs 1 standard deviation below the median for inclusion and exclusion underwent Leadership Committee review. All participants completing the first Delphi round were invited to the second round. Percent curriculum time allocated for content domains and a single subdomain were finalized. New EPAs or EPAs undergoing major revisions were reviewed. A total of 186 participants representing diverse stakeholder groups participated. One hundred fourteen completed the first Delphi round (61.3%). Of 114 invited, 77 participants completed the second round of the Delphi process (67.5%). Overall, 6 of 9 content domains met consensus, 1 content domain was removed, and 2 content domains were combined. Four subdomains of a single content domain were reviewed and met consensus. Consensus on percent time allocated per content domain and subdomain was reached. Of 55 initial EPAs, 52 final EPAs met consensus. Deliberative curriculum inquiry was successfully used to develop a consensus on US radiation oncology content domains and EPAs. These data can guide the allocation of educational time in training programs, help inform weighting for qualifying examinations, and help guide clinical training and resident assessment. [ABSTRACT FROM AUTHOR]
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- 2023
- Full Text
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