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Abstract: Cutting force information may be used for several tasks, such as tool design and trajectory optimization, tool condition monitoring, machinability testing and many others. Accordingly, cutting force measuring has become a crucial activity aimed at enhancing process performance. In this work, the development of an innovative rotating dynamometer for cutting force measurement in milling is illustrated. The device is capable of providing independent triaxial cutting force information from each cutting edge with a good dynamic response. Static and dynamic behavior of a simplified single-edge device was first investigated through the static calibration procedure, pulse tests and preliminary cutting tests. Afterwards, the dynamic properties of the final prototype clamped on the spindle of a high speed milling machine were assessed by means of standard and rotating pulse tests – i.e. pulse tests performed during spindle rotation. Eventually, cutting tests were performed on a benchmark workpiece. The experimental tests highlighted the superior features of the new device. [Copyright &y& Elsevier]

The key feature of Ganser's syndrome includes approximate answers to simple questions. The cause of this rare syndrome remains uncertain. Current classification systems categorise it as a dissociative disorder, the symptoms of which are judged as psychogenic in origin. Our review of the literature (n=151) demonstrates however that Ganser's syndrome is frequently associated with brain injury, although detailed imaging, neuropsychological, and neurological data of this for the most part do not exist. We describe a right-handed patient with Ganser's syndrome after a large left-hemispheric middle cerebral artery infarction. Detailed neuropsychological examination showed atypical lateralisation of cognitive functions with so-called crossed nonaphasia and pronounced frontal-executive dysfunctions. Regarding both psychiatric and neuropsychological aspects, we discuss how the key feature of approximate answers may be associated with frontal-executive cerebral dysfunctions. [ABSTRACT FROM AUTHOR]

Abstract: Context-awareness plays an important role in mobile distributed systems since it enables the adaptation of mobile devices to the users. However, one of the major challenges is the preservation of the users’ privacy. Many different approaches of modeling the context of the user exist, but the incorporation of privacy restrictions into context models, which makes the protection of privacy apparent, is missing. This paper presents the Context Modeling Profile (CMP), a lightweight UML (Unified Modeling Language) extension, as a visual language for context models in mobile distributed systems. The resulting models embody metainformation of the context, i.e. source and validity of context information, and reflect privacy restrictions. The profile provides several well-formedness rules for context models and supports the development of context-aware mobile applications through an adequate visual modeling language. A case study is used to illustrate the approach. [Copyright &y& Elsevier]

When sensitized erythrocytes (EA) possessing the 1st (C′1), 4th (C′4) and 2nd (C′2) components of haemolytic complement were treated with 1,4-butanediamine, C′1 but not C′4 or C′2 was removed from the cell. All the straight chain diamines of 3 to 8 carbons, with the amino groups on either end, removed C′1 with about equal facility; the diamines were considerably more active than the corresponding monoamines. C′1 could be recovered in solution following its removal from the red cell by the diamine. The rate of detachment of C′1 was quite high for the first 10 minutes, after which it was slower and followed first order kinetics. It appears that C′1 and the diamine compete for the same site on the sensitized erythrocyte. The following observations suggest that Ca++ has a role in the EAC′1 bond: (a) An increased Ca++ concentration diminishes the effect of the diamine. (b) The EAC′1 bond dissociates at low bivalent cation concentration. (c) A number of bivalent cations will preserve the EAC'1 bond, Ca++ being the most effective. [ABSTRACT FROM AUTHOR]

Abstract: Cytomegalovirus infection is generally asymptomatic in immunocompetent patients but can also provide a wide spectrum of clinical and biological signs. We report the case of a cytomegalovirus infection in an immunocompetent adult mimicking giant cell arteritis associated with polymyalgia rheumatica and complicated with pulmonary embolism. We review and discuss the venous prothrombic properties of CMV in immunocompetent patients. [Copyright &y& Elsevier]

The effects of mental diseases on the employment and working situation can be substantial. They are one of the main reasons for inability to work and reduced earning capacity. Against this background the question arises about suitable occupational reintegration measures for people with severe mental illnesses. In recent years, the principle of supported employment has been internationally shown to be increasingly more successful. In this context mentally ill people are primarily placed at a position of the first employment market and supported on-site by a job coach. This concept is inclusive, individual and evidence based. Despite proven effectiveness, it has so far been insufficiently implemented in German-speaking regions. In the future it will be a matter of considering the individual needs for assistance of mentally ill people more intensively than previously and to respond with functional and in a best-case scenario, multiprofessional and flexible offers. [ABSTRACT FROM AUTHOR]

Par sa soudaineté, la pandémie liée au virus SARS-COV-2 a été responsable d'une désorganisation majeure et globale de nos sociétés. Santé Publique France estimait au 3 juin 2020 que 102 133 personnes ont été hospitalisées en France pour COVID sévère et 29 021 personnes sont décédées. Si les conséquences médicales à court terme de cette infection sont de mieux en mieux connues, l'impact à moyen terme tant sur le plan médical, psychologique que social d'une hospitalisation pour COVID reste encore méconnu. L'étude « Post-COVID-Health » est une étude observationnelle multicentrique et ambispective ayant pour objectif d'évaluer le retentissement médico-psychosocial à 3 mois et 6 mois d'une hospitalisation pour COVID. Les données caractérisant l'état médical en phase aiguë sont en cours de recueil à partir des compte-rendu d'hospitalisation, et des questionnaires permettant de documenter les caractéristiques sociodémographiques des patients et de préciser leur état de santé médical, psychologique et social sont renseignés, via le système Voozanoo, à M3 et M6. L'évaluation psychosociale repose sur l'échelle Hospital Anxiety and Depression scale (HAD) associée à des items documentant le recours à des soins psychothérapeutiques, à la consommation de psychotropes et de substances psychoactives et le retentissement relationnel, professionnel, économique et administratif. Une évaluation cardiopulmonaire incluant scanner thoracique, EFR, test de marche et échographie cardiaque sont également réalisés, à la discrétion des médecins dans les 3 à 6 mois du début des symptômes. Plus de mille patients adultes, acceptant de participer et préalablement hospitalisés dans un des 7 centres hospitaliers inclueurs pendant la période allant du 1er mars au 30 avril, sont en cours de recrutement. Les données à 3 mois sont en cours de collection et les premiers résultats concernant l'état de santé global et notamment psychologique à 3 mois seront disponibles en août. Pourront alors être précisés le nombre de patients présentant des anomalies persistantes au niveau somatique et psychologique, la part de ceux-là nécessitant un traitement ou un suivi spécialisé et les facteurs associés à la persistance de troubles. L'étude Post-COVID-Health, permettant d'accroître nos connaissances du retentissement médico-psychosocial à moyen terme d'une hospitalisation pour COVID-19, pourra permettre de proposer une prise en charge adaptée et de mieux anticiper la prise en charge des patients en cas de nouvelle épidémie. [ABSTRACT FROM AUTHOR]