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1. Tandem versus single autologous peripheral blood stem cell transplantation as post-remission therapy in adult acute myeloid leukemia patients under 60 in first complete remission: results of the multicenter prospective phase III GOELAMS LAM-2001 trial.

Author

Chevallier, P., Fornecker, L., Lioure, B., Béné, M. C., Pigneux, A., Recher, C., Witz, B., Fegueux, N., Bulabois, C.-E., Daliphard, S., Bouscary, D., Vey, N., Delain, M., Bay, J.-O., Turlure, P., Bernard, M., Himberlin, C., Luquet, I., Ifrah, N., and Harousseau, J.-L.

Subjects
*STEM cells, *ACUTE myeloid leukemia, *THERAPEUTICS, *AUTOTRANSFUSION of blood, *TRANSPLANTATION of organs, tissues, etc.
Abstract

The article focuses on the transplantation of blood stem cell as post remission therapy in adult patients with acute myeloid leukemia. It observes the absence of potential benefit of adding high-dose melphalan supported by a second auto-HSCT compared with a conventional auto-HSCT conditioned on youth patients with acute myeloid leukemia. It states that alternative antileukemic drugs should be preferred in the case of relapse or conditioning regimen for a second auto-HSCT.

Published
2010
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