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In this paper, we investigate the generalized Radhakrishnan–Kundu–Lakshmanan equation with polynomial law using the method of dynamical systems. By using traveling-wave transformation, the model can be converted into a singular integrable traveling-wave system. Then, we discuss the dynamical behavior of the associated regular system and we obtain bifurcations of the phase portraits of the traveling-wave system under different parameter conditions. Finally, under different parameter conditions, we obtain the exact periodic solutions, and the peakon, homoclinic and heteroclinic solutions. [ABSTRACT FROM AUTHOR]

Negative body image is prevalent among women and may lead to physical and mental health problems. Social media—including China's most popular platform, WeChat Moments—aggregates multiple aspects of appearance‐related pressure and therefore is an important risk factor for negative body image. The current study examines the relationship between WeChat Moments usage and body image among female college students and the mediating mechanism of body surveillance. A sample of 151 female college students completed a 7‐day ecological momentary assessment (EMA), responded to three surveys per day, and provided a total of 2949 EMA responses. We used multilevel structural equation modeling (MSEM) to examine the hypothesized models at both the between‐ and within‐individual levels. The results showed that both overall WeChat Moments usage and appearance‐related exposure on WeChat Moments were inversely and indirectly related to body image through the mediating role of body surveillance at the between‐individual level. However, both overall WeChat Moments usage and appearance‐related exposure on WeChat Moments were positively and indirectly related to body image through body surveillance at the within‐individual level. Our findings indicate that WeChat Moments usage is associated with college women's body image differently at the between‐ and within‐individual level, and body surveillance serves as a crucial underlying mechanism. [ABSTRACT FROM AUTHOR]

In the prevention and control of influenza, it is important for healthcare workers (HCWs) to be vaccinated and recommend influenza vaccines to their patients. However, there is limited evidence on the factors influencing uptake and promotion of influenza vaccination to patients among HCWs in China. We conducted in-depth interviews among HCWs in community health centers, including general practitioners (GPs) and preventive health workers (PHWs), during January to February 2017. A total of 21 individuals, purposively selected from six community health centers covering central districts and remote suburbs in Beijing, were interviewed using semi-structured topic guides. Thematic analysis was used to analyze the interviews and coding framework was developed both inductively and deductively. Identified factors influencing influenza vaccine uptake included knowledge, perception and recognition, and prior experience of vaccine uptake. All PHWs conservatively recommended influenza vaccine because of concerns about potential patient–doctor disputes. GPs rarely recommended vaccination under their own initiative because vaccine promotion was not their duties. Notably, we found that the division of work was an underlying reason for the different behaviors regarding vaccine uptake and promotion between GPs and PHWs. Our findings highlighted a combination of misconceptions and cognitive biases limiting influenza vaccine uptake among HCWs in China. Our findings indicate that promotion of health education regarding influenza vaccination should be implemented among HCWs. Importantly, the division of work greatly affects the behaviors of HCWs. GPs, who are at the front line in the doctor–patient relationship, have a critical role in influenza vaccination programs. [ABSTRACT FROM AUTHOR]

Flexible electrochemical biosensors used for sweat analysis have aroused great interests in the field of intelligent instruments. Due to the complexity of body fluids, development of ultrasensitive and miniaturized sensors for analysis of sweat is always challengeable. In this research, we fabricate a sensitive and flexible sensor for real-time monitoring of glucose and lactate in sweat at micromolar level and millimolar level by using gold nanopine needles (AuNNs) as the signal amplification strategy. A flexible chip with gold electrode arrays was fabricated in a standard semi-conductor laboratory. AuNNs were deposited on the working electrode by electrochemical deposition method. Enzyme immobilization was carried out on the electrode surface via a cross-linker poly(ethylene glycol) diglycidylether (PEGDE), which is an important component of redox hydrogels capable of retaining the activity of the enzyme to a greater extent than other linkers like glutaraldehyde. The catalytic behavior of AuNNs under different conditions was investigated. The as-fabricated electrochemical sweat biosensor was found to achieve low detection limit down to 7 μmol L−1 for glucose, 54 μmol L−1 for lactate, respectively. The sensor also exhibited great selectivity, reproducibility and stability. In addition, human sweat samples were analyzed by the sensor, indicating its potential applications in determination of glucose and lactate as a wearable skin sensor. • A flexible electrochemical sensor is fabricated. • Au nanostructure is utilized for signal amplification. • Both glucose and lactate in sweat are detected. • High sensitivity is achieved due to Au nanostructure. • The developed sensor shows satisfactory selectivity. [ABSTRACT FROM AUTHOR]

In this paper, we consider the exact solutions of the complex cubic-quintic Ginzburg–Landau equation. By investigating the dynamical behavior of solutions of the corresponding traveling wave system of this PDE, we derive exact explicit parametric representations of the periodic wave solutions under given parameter conditions. [ABSTRACT FROM AUTHOR]

Shyness has been shown to be linked to aggression. However, whether this relationship occurs in cyberspace and the mechanisms that might affect it are largely unexplored. Based on the social fitness model, the current study examined the relationship between shyness and cyber aggression, as well as the mediating roles of passive use and relative deprivation. Moreover, according to the integration of the social information processing model and moral domain theory, moral sensitivity serves as a moderator in the direct and indirect links between shyness and cyber aggression. A total of 700 Chinese college students (M age = 18.68, 53.57% women) participated in the current study and completed multiple questionnaires, namely, the Shyness Scale, Cyber-Aggression Scale, Passive Use of Social Network Site Scale, Relative Deprivation Scale, and Ethical Sensitivity Scale. The results showed that shyness was positively associated with cyber aggression through the multiple mediating effects of passive use and relative deprivation. Additionally, moderated mediation analysis indicated that moral sensitivity moderated the direct and indirect relationship between shyness and cyber aggression. A high level of moral sensitivity weakened the association of shyness with cyber aggression and the association of relative deprivation with cyber aggression, supporting the moderated mediation model. This study implicates the underlying mechanisms of the relationship between shyness and cyber aggression and preventative interventions to reduce the risk of cyber aggression. [ABSTRACT FROM AUTHOR]

Numerous studies have emphasized the importance of examining psychological distress during the COVID-19 pandemic. It is important to identify the factors that affect the influence of COVID-19 on people's mental health. The present research was a three-wave longitudinal study (N = 1495) examining the concurrent and prospective relations of good personality with subjective well-being during the COVID-19 pandemic. Results showed that good personality positively predicted the subsequent well-being after controlling for the respective autoregressive effects and Big Five personality traits. Specifically, individuals who scored higher on measures of good personality tended to maintain higher well-being in the face of COVID-19. However, subjective well-being could positively predict subsequent personality only at the first time point. In addition, the prospective effect of good personality on subjective well-being was greater than the reverse effect. These findings support the opinion that as a positive value orientation in personality, good personality has a significant positive impact on the response to the pandemic situation. [ABSTRACT FROM AUTHOR]

Background: Influenza vaccination has been suggested to protect against death and recurrent events among patients with cardiovascular disease or chronic obstructive respiratory disease, but there is limited evidence in older adults, who have higher risks of influenza-associated hospitalization and mortality.Methods: Patients aged ≥60 years hospitalized for cardiovascular or respiratory diseases from the Beijing Urban Employee Basic Medical Insurance database during 3 influenza seasons (2013-2014 through 2015-2016) were pooled to estimate the effects of influenza vaccination on hospitalization outcomes. Vaccination status was ascertained through cross-referencing the Beijing Elderly Influenza Vaccination database. The summer months (June-August) were used as a reference period to adjust for unmeasured confounders during influenza seasons.Results: After adjustment for both measured and unmeasured confounders, influenza vaccination was associated with lower risks of in-hospital deaths among patients hospitalized for cardiovascular (odds ratio [95% confidence interval], 0.85 [.68-1.06]) or respiratory diseases (0.66 [.54-.82]). Influenza vaccination was associated with a lower risk of readmission among patients with cardiovascular (odds ratio [95% confidence interval], 0.81 [.69-.95]) but not respiratory diseases (1.12 [.92-1.35]). Influenza vaccination was also associated with lower direct medical costs, but not with length of stay.Conclusions: Influenza vaccination protected against hospitalization outcomes among older adults with cardiovascular or respiratory diseases. [ABSTRACT FROM AUTHOR]

Lindane is a highly toxic organochlorine pesticide and widely exist in water with harmful effects on fish. Although some genes have been found to be regulated by lindane in fish, the transcriptional response of fish exposed to lindane is still unknown. In this research, the transcriptional changes of zebrafish larvae exposed to 0.2 mg/L lindane from 96 to 120 hpf were studied by RNA sequencing. Our transcriptome identified 554 up-regulated and 118 down-regulated genes and the differentially expressed genes were closely related to the neuromast development, RNA silencing genes, ion transport, and response to estrogen. In addition, we characterized two sensitive and novel lindane-induced ABCG (ATP binding cassette G subfamily) transporter genes- abcg5 and abcg8. Abcg5 and abcg8 genes are located on chromosome 13 of zebrafish and contain 1956/2024 bp open reading frame. The polypeptide deduced by CDS amplification contains 652/676 amino acids and has most of the functional domains and key residues defined in human and mouse ABCG5/Abcg5 or ABCG8/Abcg8. Only when the co-expression of Abcg5 and Abcg8 enable them to transport to the cell membrane surface in 293T cells. In addition, lindane can induce the transcriptional expression of abcg5 and abcg8 genes, and overexpression of Abcg5 and Abcg8 significantly reduced the toxicity of lindane to zebrafish larvae, which means that zebrafish Abcg5 and Abcg8 are potential efflux transporters of lindane. Therefore, these findings provide useful insights for further understanding the zebrafish larvae's transcriptional response and detoxification ability after acute exposure to lindane. Unlabelled Image • Toxicity of lindane on zebrafish larvae was determined. • Transcriptomic events regulated by acute lindane exposure were characterized in zebrafish larvae. • Cloning, expression and subcellular localization of zebrafish Abcg5 and Abcg8 were investigated. • Transcriptional response and function of zebrafish Abcg5 and Abcg8 in detoxification of lindane were studied. [ABSTRACT FROM AUTHOR]