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1. Two new polyketides from endophytic fungus Pestalotiopsis sp. HQD-6 isolated from the Chinese mangrove plant Rhizophora mucronata.

Author

Zhou, Jing, Zheng, Dong-Yao, and Xu, Jing

Subjects
*BIOLOGICAL products, *MEDICINAL plants, *HERBAL medicine, *FUNGI, *ANTI-infective agents, *ANTIOXIDANTS, *NUCLEAR magnetic resonance spectroscopy, *POLYKETIDES, *MASS spectrometry, *RESEARCH funding, *MOLECULAR structure, *CHROMATOGRAPHIC analysis, *COLLECTION & preservation of biological specimens, *BIOLOGICAL assay, *CHINESE medicine, *METABOLITES, *PHARMACODYNAMICS
Abstract

Mangrove endophytic fungi were proved to be a prolific resources for bioactive secondary metabolites. Two new polyketides, pestalotiopin B (1) and pestalotiopyrone N (2) were obtained from the ethyl acetate extracts of the rice solid cultures of the mangrove endophytic fungus Pestalotiopsis sp. HQD-6. The structures of 1 and 2 were determined by detailed interpretation of NMR spectroscopic analysis and HR-ESIMS. All of the isolates were evaluated for their antimicrobial, antioxidant and cytotoxic activities. [ABSTRACT FROM AUTHOR]

Published
2022
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