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Objective: The aim of this study is to investigate the effect of intrauterine insemination (IUI) performed simultaneously with ultrasound detected follicular rupture during biological reproduction window on pregnancy rates in patients with unexplained infertility undergoing ovulation induction (OI) cycles with gonadotropins. Material and Methods: Three-hundred and twenty-five patients with unexplained infertility were included in this prospective cohort study, who received recombinant follicular stimulating hormone (75-150 IU/day) or Human Menopausal Gonadotropin starting from the 2nd to 3rd days of the cycle. IUI was carried out with ultrasonographic monitoring of the follicles. The presence of free fluid within the Douglas pouch, detection of corpus luteum, and/or loss of the dominant follicle was interpreted as follicular rupture. Pregnancy rates with or without follicular rupture were compared after 14 days. Results: Among those with follicular rupture, the time between administration of recombinant hCG and IUI was significantly longer as compared to those without follicular rupture (p<0.001). ß hCG was positive at 14 days after IUI in 19.01% (31/163) and 13.92% (22/158) of the cases with or without follicular rupture, respectively. The difference in pregnancy rates was not significant (p=0.219). Conclusion: IUI simultaneously performed with ultrasound-detected follicular rupture in OI cycles with gonadotropins does not increase pregnancy rate. [ABSTRACT FROM AUTHOR]

Objective: We aim to investigate the relationship between the pro-inflammatory markers and sperm retrieval (SR) in microdissection testicular sperm extraction (micro-TESE) procedure in patients with non-obstructive azoospermia (NOA). Material and Methods: This retrospective study was conducted with 318 patients who applied to our in vitro fertilization Unit between April 2017 and December 2020 and underwent micro-TESE for NOA. Patients with (Group 1) and without (Group 2) sperm retrieved were compared in terms of age, infertility duration, body mass index (BMI), hormone profile, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-eosinophil ratio (MER), platelet-to-lymphocyte ratio (PLR), and a new marker of eosinophil-tolymphocyte ratio (ELR). Results: SR from the micro-TESE procedure was achieved in 183 (57.5%) of 318 patients. Testicular tissue biopsies were performed simultaneously in all cases. There was no statistically significant difference between the groups concerning BMI. When the groups were compared regarding the pro-inflammatory markers, while the NLR, MER, and PLR were found to be statistically higher in Group 2 cases; ELR was similar among groups. Conclusion: The MER, NLR, and PLR were determined to be associated with negative micro-TESE results. Particularly PLR seems to have a poor prognostic value in these patients. A prognostic value of the ELR which was a new biomarker was not determined in SR from the TESE procedure. [ABSTRACT FROM AUTHOR]

Copyright of Perinatal Journal / Perinatoloji Dergisi is the property of Deomed Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi Dergisi is the property of Istanbul Tip Fakultesi Dergisi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Turkish Society of Obstetrics & Gynecology / Türk Jinekoloji ve Obstetrik Derneği Dergisi is the property of Turkish Society of Obstetrics & Gynecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To determine whether the measurement of beta-human chorionic gonadotropin (Ã-hCG) levels in vaginal fluid is useful for the diagnosis of premature rupture of membranes (PROM). Material and Methods: A total of 92 pregnant women between 24 and 40 weeks gestation participated in this study. The patients with fluid leaking from the vagina were designated Group 1, the patients with no fluid leaking from the vagina were Group 2, and those with a suspicion of fluid leaking from the vagina were classified as Group 3. Irrigating the posterior vaginal fornix with 5 mL sterile saline was used to measure Ã-hCG levels of the patients. Receiver operator curve (ROC) analysis was used to determine the cut-off value for a positive diagnosis. Results: The Ã-hCG levels of vaginal fluid were measured as 20.5±25.0 mlU/mL, 254.6±346.8 mlU/mL, and 74.3+100.8 mlU/mL in Group 1, Group 2, and Group 3, respectively. Vaginal Ã-hCG level was higher statistically significantly in Group 2 than Group 1 and 3 (p<0.001). 100 mlU/mL was accepted as a cut-off value by using the receiver operating characteristic curve. According to 100 mlU/mL, sensitivity, specificity, positive predictive and negative predictive values were calculated as 71.2, 100, 100, and 65.1%, respectively. Conclusion: The study showed that the measurement of Ã-hCG level in vaginal washing fluid is an efficient and easy diagnostic test for predicting the amount of fluid leaking from the vagina. However, due to the low negative predictive value of the test, it would not be convenient in daily practice. [ABSTRACT FROM AUTHOR]

Copyright of Journal of the Turkish-German Gynecological Association is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To compare power Doppler flow mapping characteristics of endometrial polyps and submucosal fibroids and analyze whether different power Doppler characteristics can help to differentiate these focal endometrial lesions. Methods: Fifty-eight women (median age, 37 years; range, 25-51 years) presenting with abnormal uterine bleeding and infertility on transvaginal ultrasund suggested focal endometrial lesions underwent sonohysterography were included in this prospective study. Three different vascular patterns were defined: Pattern A: single-vessel pattern, Pattern B: rim-like vessel pattern C: multiple vessel pattern. These were compared with the final histopathological diagnosis. Results: Histological diagnoses were as follows: Endometrial polyp 40 (69%), submucousal myoma 18 (31%). Power Doppler signals were observed in 53 of these; they were not observed in five patients with endometrial polyps. We find out 75% pattern A, 2.5% pattern B and 7.5% pattern C in vascularized polyps, and also submucous myomas we find out 5.6% pattern A, 66.7% pattern B and 27.8% pattern C. The sensitivity, specificity and positive and negative predictive values for single vessel pattern in diagnosing endometrial polyps were 80, 100, 100, and 69.23%; for multiple vessels pattern in diagnosing submucousal myomas were 27.78, 92.5, 62.5 and 74%; for rim-like vessel pattern in diagnosing submucosal fibroids, they were 72.22, 100, 100 and 88.9%, respectively. Conclusion: Power Doppler blood flow mapping is reasonable in the diagnosis of intrauterine focal lesions and is practical in distinguishing endometrial polyps and submucosal fibroids. [ABSTRACT FROM AUTHOR]