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Copyright of Türk Pediatri Arşivi is the property of Aves Yayincilik Ltd. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Our aim was to investigate whether Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte Ratio (PLR) and Mean Platelet Volume parameters (MPV) may be utilized as inflammatory markers of chronic rhinosinusitis with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP). Methods: This retrospective multicenter study was performed on 647 patients who were underwent endoscopic sinus surgery. Clinical and preoperative laboratory data of patients were screened retrospectively. The study and control groups were compared for the parameters NLR, PLR, MPV, neutrophils, lymphocytes, and platelets. Results: Of the 647 patients, 313 were in the CRSwNP group, 334 were in the CRSsNP group. There were 93 individuals in the control group. NLR and PLR levels were significantly higher in study groups compared to control group (p < 0.001). But no statistically significant differences were identified between CRSwNP group and CRSsNP group in terms of NLR, PLR, MPV levels. Conclusion: We speculate that high NLR and PLR values may be useful inflammatory indicator for CRSwNP and CRSsNP groups. We believe these parameters will have increasing clinical use in the future on treatment options and prognosis. [ABSTRACT FROM AUTHOR]

Copyright of ENT Updates is the property of Continuing Education & Scientific Research Association (CESRA) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical & Experimental Investigations is the property of Modestum Publications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: In this study, we aimed to evaluate the patients with obstructive sleep apnea syndrome (OSAS) for otorhinolaryngological manifestations. Methods: A total of 347 patients who were diagnosed to have OSAS by polysomnography between April 2010 - September 2015 were included in the study. Data of patients, which were collected from patient registry records on hospital computer automation system, were analyzed, retrospectively. Results: A total of 117 otorhinolaryngological manifestations diagnosed in all of the OSAS patients. According to the polysonographic findings, 26 of these patients had simple snoring while 30 had mild OSAS, 20 had moderate OSAS and 41 had severe OSAS. When the OSAS group (mild-moderate-severe) (n=91) was examined, 68 patients had nasal septum deviation, 28 had inferior concha hypertrophy, 23 had tongue base hypertrophy, 20 had tonsillar hypertrophy and 33 had elongated soft palate. When the simple snoring group was examined, 20 patients had nasal septum deviation, 8 had inferior concha hypertrophy, 5 had tongue base hypertrophy, 3 had tonsillar hypertrophy and 4 had elongated soft palate. When both groups were compared, it was seen that the only significant difference was that the OSAS group had higher values in terms of elongated soft palate (p< 0.05). When OSAS group was examined, nasal septum deviation and concha hypertrophy were the most commonly coexisting conditions among all otorhinolaryngologic diagnosis (12.09%). Similarly, in OSAS group, nasal septum deviation, tongue base hypertrophy and elongated soft palate were the most commonly coexisting diagnosis (8.79%).There was only 1 patient having all the otorhinolaryngologic diagnosis (1.1%). Conclusion: Obstructive sleep apnea syndrome cause severe morbidity and mortality. Otorhinolaryngological pathologies have an important role in the physiopathology of OSAS and early diagnosis has a great importance in reducing mortality and morbidity. [ABSTRACT FROM AUTHOR]

Background/aims: In this study, we aimed to evaluate the histopathological effects of thymoquinone treatment of the nasal mucosa in a rabbit model of allergic rhinitis, and we compared its effects with those of nasal mometasone furoate.Methods: A total of 24 male New Zealand rabbits were used. The animals were randomly assigned to one of four groups. Group 1 received no treatment, while group 2 underwent ovalbumin (OVA) sensitization only. Group 3 was the study group; after OVA sensitization, the rabbits were treated with intranasal thymoquinone. The group 4 rabbits received mometasone furoate for 7 days after OVA sensitization. Mucosal structures were stained with hematoxylin and eosin, while toluidine blue was used to stain mast cells. Apoptosis was evaluated using a TUNEL assay.Results: In the positive control groups, including the thymoquinone and intranasal mometasone furoate groups, intraepithelial and submucosal inflammation and goblet cell hypertrophy were significantly decreased compared to group 2 (p < 0.001). The cilial structure was normal, as was the chondrocyte structure in both treatment groups.Conclusion: This is the first study to evaluate the histopathological effects of thymoquinone in an allergic rhinitis model. Thymoquinone reduced allergic inflammation and may be valuable for treating allergic rhinitis. However, additional studies are needed. [ABSTRACT FROM AUTHOR]

Pilomatrixoma is a benign appendageal tumor derived from hair matrix cells which is also known as calcifying epithelioma of Malharbe. It usually appears as a solitary, asymptomatic, firm nodule. It is most common on the face and neck, but is occasionally found somewhere else on the body. A 18-year-old female was referred to dermatology clinic with a two year history of painless subcutaneous nodule in front of her right ear. The computed tomography imaging study demonstrated 8.5x12 mm subcutaneous mass lesion with calcification. Histopathological examination of the excised material showed the presence of basaloid cells associated with phantom cells, with areas of multinucleated giant cells, pigmented macrophages and widespread dystrophic calcification compatible with pilomatrixoma. In this case, we wished to present a patient who underwent excisional biopsy as a result of computed tomography imaging and whose pathological result was reported to be pilomatrixoma. Pilomatrixoma has long been supposed to be an infrequent tumor, but it may be more common than previously realized, so the clinicians must keep in mind the diagnosis of pilomatrixoma for subcutaneous nodules on the head and neck. [ABSTRACT FROM AUTHOR]