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Background: The aim of this study was to compare local control and maximum mouth opening in excision the buccinator muscle with the skin versus excision the buccinator muscle without the skin. Methodology: This study was conducted on 40 patients with buccal squamous cell carcinoma (BSCC) without previous treatment, also T1 to T3 and N0 to N2 squamous cell carcinoma was involved in this study. The patients were divided randomly in 2 groups, 20 patients for each group. All patients were assessed for local recurrence for 1 year. Maximum mouth opening was measured preoperative and compared by postoperative measuring. Results: The local control was (100%) in the study group and (95%) in the control group, but There were no statistically significant differences between the two interventions (P value 1). The maximum mouth opening was decreased postoperatively than preoperatively and in study group than the control one,but there was no statistically significance difference (P- value 0.22). Conclusions: Excision the buccinator muscle with its associated skin seems to decrease the local recurrence and seems to decrease the maximum mouth opening, but with no statistically significant differences between the two interventions. Indicating the needs for further studies. [ABSTRACT FROM AUTHOR]

Background and objective Supramandibular facial lymph nodes (SFLNs) are one of the unusual sites of lymph nodes metastases. This prospective study investigated the possible involvement of SFLNs in cases of head and neck carcinoma. Patients and methods SFLNS were identified and dissected from 30 neck dissections obtained from 30 patients (22 male individuals and eight female individuals) with squamous cell carcinoma (SCC) of the oral cavity without locoregional recurrence or distant metastases. Result Histopathological examination of the removed SFLN nodes proved positive for metastases in nine neck dissections, five cases of buccal mucosa SCC (41.7% of the cases) and four cases of alveolar margin SCC (44.4% of the cases). Conclusion SFLNs are a probable site of lymph node metastases in SCC of the alveolar margin and buccal mucosa. Careful dissection above the lower margin of the mandible can safely remove these nodes without significant injury to the marginal mandibular branch of the facial nerve. [ABSTRACT FROM AUTHOR]

Introduction Conservative surgery has become a well-established alternative to mastectomy in the treatment of breast cancer. However, in case of larger lesions or small-sized breasts, the removal of adequate volumes of breast tissue to achieve tumor-free margins and reducing the risk of local relapse may compromise the cosmetic outcome, causing unpleasant results. To address this issue, surgical techniques, the so-called oncoplastic techniques, have been introduced in recent years to optimize the efficacy of conservative surgery in terms of both local control and cosmetic results. Patients and methods A Clinical Interventional descriptive single arm randomized prospective study, conducted on twenty female patients presenting with operable breast cancer stages 1 and 2 located at the Upper or Central breast. Ages ranging 25 to 75 years to be treated using the “round block” technique. Results Cosmetic results were found to be excellent in three cases, good in eight cases, fair in five cases, and poor in two cases. In this study, the cosmetic results were unacceptable (fair and poor) in patients who underwent 25% resection or in whom the resected area was part of the lower portion of the breast. Conclusion These techniques are useful for performing breast-conserving surgery in the upper portion of the breast. However, if the excision volume is greater than 20% or excision of part of the lower portion of the breast is required, other procedures should be considered. This article discusses the indications, advantages, and limitations of the round block breast-conserving oncoplastic techniques and its results in terms of feasibility, maintaining breast esthetics, limitations, and early complications. [ABSTRACT FROM AUTHOR]

Human bocavirus (HBoV) is a prevalent virus worldwide and is mainly associated with respiratory disorders. Recently, it was detected in several disease conditions, including cancers. Colorectal cancer (CRC) is the third main cause of cancers worldwide. Risk factors that initiate cell transformation include nutritional, hereditary and infectious causes. The aim of the current study was to screen for the presence of HBoV in solid tumors of colorectal cancer and to determine the genotypes of the detected strains. Surgically excised and paraffin-embedded colorectal cancer tissue specimens from 101 male and female patients with and without metastasis were collected over the last four years. Pathological analysis and tumor stages were determined. The presence of HBoV was screened by polymerase chain reaction, and the genotype of the detected HBoV was determined by direct gene sequencing. Most of the examined specimens were adenocarcinoma with mucinous activity in many of them. Twenty-four out of 101 (23.8 %) CRC tissue specimens were found to contain HBoV-1. Low sequence diversity was recorded in the detected strains. The virus was detected in both male and female patients with an age range of 30-75 years. It is proposed that HBoV-1 could play a potential role in the induction of CRC. [ABSTRACT FROM AUTHOR]

Purpose The aim of the study was to determine the feasibility and accuracy of sentinel lymph node biopsy (SLNB) in patients with advanced breast cancer after preoperative chemotherapy. Patients and methods A prospective study was conducted on 73 patients with advanced operable breast carcinoma previously treated with preoperative chemotherapy. Sentinel lymph node (SLN) mapping was performed at the time of surgery. Following surgery all patients received comprehensive postoperative radiotherapy at 50 Gy/5 weeks. Results Seventy-three patients with a median age of 52 years who had been previously treated with preoperative chemotherapy at Menofia University Hospital and National Cancer Institute (NCI) between May 2006 and May 2013 were selected for this study. The SLN detection rate was 79.5%. Thirty-three of 58 patients (56.9%) had successfully mapped positive SLNs. The false-negative rate was 22.4%. Conclusion This study confirms the feasibility of SLNB after preoperative chemotherapy in the case of advanced operable breast cancer. According to the detection rate and false-negative rate SLNB may predict metastatic disease in the axilla of patients with tumor response following preoperative chemotherapy. [ABSTRACT FROM AUTHOR]