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Current signal systems for managing road traffic in many urban areas around the world lack a coordinated approach to detecting the spatial and temporal evolution of congestion across control regions within city networks. This severely inhibits these systems’ ability to detect reliably, on a strategic level, the onset of congestion and implement effective preventative action. As traffic is a time-dependent and non-linear system, Chaos Theory is a prime candidate for application to Urban Traffic Control (UTC) to improve congestion and pollution management. Previous applications have been restricted to relatively uncomplicated motorway and inter-urban networks, arguably where the associated problems of congestion and vehicle emissions are less severe, due to a general unavailability of high-resolution temporal and spatial data that preserve the variability in short-term traffic patterns required for Chaos Theory to work to its full potential. This paper argues that this restriction can now be overcome due to the emergence of new sources of high-resolution data and large data storage capabilities. Consequently, this opens up the real possibility for a new generation of UTC systems that are better able to detect the dynamic states of traffic and therefore more effectively prevent the onset of traffic congestion in urban areas worldwide. [ABSTRACT FROM AUTHOR]

Heavy Goods Vehicles, HGV, and Light Goods Vehicles, LGV, are a significant contributor to air pollution problems in urban areas. This paper quantifies the contribution to the environment of the deliveries to a single, large city employer addressing a research gap in the literature. Analysis of data from comprehensive surveys carried out over two years demonstrated that freight delivery traffic generated by an urban establishment with multiple properties in a compact urban setting, is characterised by a high proportion of LGV consistent with recent national and international trends. Also, despite freight traffic is only 10% of local traffic, more than 50% serves the single establishment, suggesting a different approach to policy making driven by the employer should be explored. The modelling results showed, relatively, the largest contribution to total emissions comes from HGVs in the AM peak, 13.8%, 43.7%, 9.2% for CO2, NOx and PM respectively. LGV contribute less, with 5.5%, 3.8%, 6% for CO2, NOx and PM respectively but more responsible for local congestion due to their numbers. This research is the first known study of its type and with the unique combination of measurement and traffic microsimulation allowed consideration of more effective traffic management strategies as well as providing evidence to support a consolidation centre for deliveries outside the city with fewer electric or low emissions last mile vehicles reducing substantially the environmental impact. The research outputs are relevant to many other similar cases in UK and Europe. The paper contributes to the ongoing development of research and policy looking to achieve sustainable urban logistics through receiver and purchasing led initiatives. [ABSTRACT FROM AUTHOR]

Background The timely publication of findings in peer-reviewed journals is a primary goal of clinical research. In clinical trials, the processes leading to publication can be complex from choice and prioritization of analytic topics through to journal submission and revisions. As little literature exists on the publication process for multicenter trials, we describe the development, implementation, and effectiveness of such a process in a multicenter trial. Methods The Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) trial included a data coordinating center (DCC) and clinical centers that recruited and followed more than 1,000 patients. Publication guidelines were approved by the steering committee, and the publications committee monitored the publication process from selection of topics to publication. Results A total of 73 manuscripts were published in 23 peer-reviewed journals. When manuscripts were closely tracked, the median time for analyses and drafting of manuscripts was 8 months. The median time for data analyses was 5 months and the median time for manuscript drafting was 3 months. The median time for publications committee review, submission, and journal acceptance was 7 months, and the median time from analytic start to journal acceptance was 18 months. Conclusions Effective publication guidelines must be comprehensive, implemented early in a trial, and require active management by study investigators. Successful collaboration, such as in the HALT-C trial, can serve as a model for others involved in multidisciplinary and multicenter research programs. [ABSTRACT FROM AUTHOR]

This paper provides an assessment of the tools required to fulfil the air quality management role now expected of local authorities within the UK. The use of a range of pollution monitoring tools in assessing air quality is discussed and illustrated with evidence from a number of previous studies of urban background and roadside pollution monitoring in Leicester. A number of approaches to pollution modelling currently available for deployment are examined. Subsequently, the modelling and monitoring tools are assessed against the requirements of local authorities establishing air quality management areas. Whilst the paper examines UK-based policy, the study is of wider international interest. [ABSTRACT FROM AUTHOR]

Background: The timely publication of findings in peer-reviewed journals is a primary goal of clinical research. In clinical trials, the processes leading to publication can be complex from choice and prioritization of analytic topics through to journal submission and revisions. As little literature exists on the publication process for multicenter trials, we describe the development, implementation, and effectiveness of such a process in a multicenter trial.Methods: The Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) trial included a data coordinating center (DCC) and clinical centers that recruited and followed more than 1,000 patients. Publication guidelines were approved by the steering committee, and the publications committee monitored the publication process from selection of topics to publication.Results: A total of 73 manuscripts were published in 23 peer-reviewed journals. When manuscripts were closely tracked, the median time for analyses and drafting of manuscripts was 8 months. The median time for data analyses was 5 months and the median time for manuscript drafting was 3 months. The median time for publications committee review, submission, and journal acceptance was 7 months, and the median time from analytic start to journal acceptance was 18 months.Conclusions: Effective publication guidelines must be comprehensive, implemented early in a trial, and require active management by study investigators. Successful collaboration, such as in the HALT-C trial, can serve as a model for others involved in multidisciplinary and multicenter research programs.Trial Registration: The HALT-C Trial was registered with clinicaltrials.gov (NCT00006164). [ABSTRACT FROM AUTHOR]