1. Synthesis, Crystal Structure, and.
- Author
-
Ben Salah, Bochra, Chaari, Najla, Rekik, Awatef, Ben Hsouna, Anis, Trigui, Mohamed, and Kossentini, Mohamed
- Subjects
CHEMICAL synthesis ,CRYSTAL structure research ,ANTIBACTERIAL agents ,TRIAZOLES synthesis ,HYDRAZINE - Abstract
A straightforward method has been developed for the synthesis of 1,2,4-triazol-3-one 3 and 1,2,4-triazoles 6a, 6b, 6c, 6d starting from N
1 -substituted- N1 -tosylhydrazonates 2 and hydrazine monohydrate. This methodology affords a number of 1,2,4-triazol-3-one 3 and 1,2,4-triazoles 6a, 6b, 6c, 6d in reasonable yields. The structures of all new compounds were elucidated using infrared,1 H and13 C NMR, high-resolution , elemental analysis, and the X-ray crystallography (for compounds 3 and 6a). Some of the newly synthesized compounds were screened for their . [ABSTRACT FROM AUTHOR]- Published
- 2015
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