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1. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription.

Author

Chandel, N.S. and Maltepe, E.

Subjects
MITOCHONDRIA, REACTIVE oxygen species, HYPOXEMIA, ERYTHROPOIETIN
Abstract

Looks at a study which investigated the hypothesis that mitochondria which increased the generation of reactive oxygen species (ROS) during hypoxia, acted as O2 sensors. In-depth look at mammalian cells; Details on the transcriptional activation of erythropoietin and the vascular endothelial growth factor; Methodology used to conduct the study; Results of the study.

Published
1998
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