6 results on '"Chen, Boqian"'
Search Results
2. A Bioinspired Sweat‐Drainable Janus Electrophysiological Electrode for Scientific Sports Training.
- Author
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Li, Pengfei, Bao, Yuan, Chen, Boqian, Liu, Xi, Yang, Hui, Li, Quantong, Chen, Tongsheng, Fan, Jianlin, Hu, Chuan, and Ling, Yunzhi
- Subjects
PHYSICAL training & conditioning ,PERSPIRATION ,ELECTROPHYSIOLOGY ,ELECTRODES ,TECHNOLOGICAL innovations ,HUMAN-computer interaction ,NANOWIRES - Abstract
Recent technological innovations in wearable electronics offer possibilities to perform real‐time monitoring of electrophysiological parameters, such as ECG, EMG, and EEG. To achieve accurate and long‐term electrophysiological measurement, great signs of progress have been made in the skin–electrode interfacial problems; nevertheless, the challenges related to sweat have not been fully resolved. Excessive sweat between human skin and the electrode usually fails to achieve a conformal and intact contact, and the nonconductive barriers will lead to a high skin–electrode impedance. Inspired by the structure of liquid directional movement in nature, a Janus gold nanowires/nitrocellulose (AuNWs/NC) electrophysiological electrode with conical micropores is developed to solve interfacial problems caused by sweat. The Janus AuNWs/NC electrodes spontaneously wick sweat from the AuNW side to the NC side, thus keeping intimate skin–electrode contact and low interfacial impedance to ensure a high‐fidelity signal during the long‐term monitoring. By integrating Janus AuNWs/NC electrode with circuit modules and advanced algorithms, a real‐time visualization system is developed for muscle activity intensity. This system is applied to precisely evaluate the muscle controllability and assess the muscle balance ability, which presents great potentials for health monitoring, sports training, and the areas of human–computer interaction. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
3. Generation of a pdmH1N1 2018 Influenza A Reporter Virus Carrying a mCherry Fluorescent Protein in the PA Segment.
- Author
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Bu, Ling, Chen, Boqian, Xing, Lei, Cai, Xuejun, Liang, Shuhua, Zhang, Liying, Wang, Xinhua, and Song, Wenjun
- Subjects
FLUORESCENT proteins ,INFLUENZA A virus ,INFLUENZA viruses ,ANTIVIRAL agents ,VIRAL transmission - Abstract
Influenza A virus (IAV) is a major human pathogen associated with significant morbidity and mortality worldwide. Through serial passage in mice, we generated a recombinant pdmH1N1 2009 IAV, A/Guangdong/GLW/2018 (GLW/18-MA), which encodes an mCherry gene fused to the C-terminal of a polymerase acidic (PA) segment and demonstrated comparable growth kinetics to the wild-type. Nine mutations were identified in the GLW/18-MA genome: PA (I61M, E351G, and G631S), NP (E292G), HA1 (T164I), HA2 (N117S and P160S), NA (W61R), and NEP (K44R). The recombinant IAV reporter expresses mCherry, a red fluorescent protein, at a high level and maintains its genetic integrity after five generations of serial passages in Madin-Darby Canine Kidney cells (MDCK) cells. Moreover, the imaging is noninvasive and permits the monitoring of infection in living mice. Treatment with oseltamivir or baicalin followed by infection with the reporter IAV led to a decrease in fluorescent protein signal in living mice. This result demonstrates that the IAV reporter virus is a powerful tool to study viral pathogenicity and transmission and to develop and evaluate novel anti-viral drugs, inhibitors, and vaccines in the future. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
4. Color tunable Ca8ZnM(PO4)7 (M = Lu/Tb, Lu/Eu, Tb/Eu) phosphors: luminescence, energy transfer and thermal stability studies for n-UV white LEDs.
- Author
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Yan, Jing, Jiang, Chunyan, Xian, Yulun, Zhou, Jianbang, Li, Hong, Chen, Boqian, Xing, Jingchao, Chen, Zhitao, and Li, Junhao
- Subjects
TERBIUM ,PHOSPHORS ,HEAT transfer ,ENERGY transfer ,LIGHT emitting diodes ,THERMAL stability ,LUMINESCENCE - Abstract
A series of Tb
3+ - and Eu3+ -doped Ca8 ZnLu(PO4 )7 (CZLP:Tb3+ and CZLP:Eu3+ ) as well as Ca8 ZnTb(PO4 )7 :Eu3+ (CZTP:Eu3+ ) phosphors have been prepared via the traditional high-temperature solid-state reaction. X-ray powder diffraction (XRD) patterns of the as-prepared phosphors indicate that the introduction of Tb3+ or Eu3+ affects neither the phase impurity nor the crystal structure of the CZLP host lattice. The concentration dependent photoluminescence (PL) spectra reveal that even if Lu3+ was fully substituted by the dopants, Tb3+ or Eu3+ , the phenomenon of concentration quenching would not occur. Color tunable emissions from green to red can be realized by adjusting the type of doping ion (Tb3+ and Eu3+ ) and their relative concentration. Furthermore, the energy transfer from Tb3+ to Eu3+ was confirmed and the mechanism was determined to be the dipole–quadrupole interaction. In addition, the quantum efficiencies were found to be 0.61, 0.58 and 0.85 for CZTP, CZTP:0.2Eu3+ and CaZnEu(PO4 )7 (CZEP), respectively. As a result, a white light emitting diode (WLED) device was fabricated using the optimal CZTP:0.2Eu3+ yellow phosphor, the BaMgAl10 O17 :Eu2+ (BAM:Eu2+ ) blue phosphor and a 370 nm near-ultraviolet (n-UV) chip. The obtained device displays a suitable color rendering index (CRI, ∼81.3) and correlated color temperature (CCT, ∼2634 K) value, indicating its potential application in n-UV LEDs. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
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5. Role of pericyte‐derived SENP1 in neuronal injury after brain ischemia.
- Author
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Sun, Meiling, Chen, Xiang, Yin, Yi‐Xuan, Gao, Yinping, Zhang, Li, Chen, Boqian, Ji, Yin, Fukunaga, Kohji, Han, Feng, and Lu, Ying‐Mei
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CEREBRAL ischemia ,POST-translational modification ,BRAIN injuries ,PERICYTES ,LASER microscopy - Abstract
Aims: SUMOylation is a posttranslational modification related to multiple human diseases. SUMOylation can be reversed by classes of proteases known as the sentrin/SUMO‐specific proteases (SENPs). In the present study, we investigate the potential role of SENP1 in pericytes in the brain ischemia. Methods: Pericyte‐specific deletion of senp1 mice (Cspg4‐Cre; senp1f/f) were used for brain function and neuronal damage evaluation following brain ischemia. The cerebral blood vessels of diameter, velocity, and flux were performed in living mice by two‐photon laser scanning microscopy (TPLSM). Biochemical analysis and immunohistochemistry methods were used to address the role and mechanism of pericyte‐specific SENP1 in the pathological process of brain ischemia. A coculture model of HBVPs and HBMECs mimicked the BBB in vitro and was used to evaluate BBB integrity after glucose deprivation. Results: Our results showed that senp1‐specific deletion in pericytes did not affect the motor function and cognitive function of mice. However, the pericyte‐specific deletion of senp1 aggravated the infarct size and motor deficit following focal brain ischemia. Consistently, the TPLSM data demonstrated that SENP1 deletion in pericytes accelerated thrombosis formation in brain microvessels. We also found that pericyte‐specific deletion of senp1 exaggerated the neuronal damage significantly following brain ischemia in mice. Moreover, SENP1 knockdown in pericytes could activate the apoptosis signaling and disrupt the barrier integrity in vitro coculture model. Conclusions: Our findings revealed that targeting SENP1 in pericytes may represent a novel therapeutic strategy for neurovascular protection in stroke. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
6. Heat transfer enhancement by a focused ultrasound field.
- Author
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Wang, Xiaowu, Wan, Zhenping, Chen, Boqian, and Zhao, Yongling
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HEAT transfer ,HEAT transfer coefficient ,NATURAL heat convection ,ACOUSTIC streaming ,SPEED of sound ,ULTRASONIC effects - Abstract
A focused ultrasound field is set up in a heat transfer cavity with an elliptical cross section. A sound source and a heat source are designed at the two focus points where the sound intensity is reinforced based on the interference and standing wave criteria. The sound intensities and heat transfer coefficients of the cavity with a focused ultrasonic field and an ordinary cavity with a rectangular cross section are measured under the natural convection heat transfer regime. The distribution of the heat transfer coefficient matches the distribution of the sound intensity. The heat transfer performance is then enhanced in the cavity with a focused ultrasonic field. The cavitations and acoustic streaming characteristics in the cavity with a focused ultrasonic field and the ordinary cavity are also studied. The velocity of acoustic streaming is larger in the cavity with a focused ultrasonic field than in the ordinary cavity, and no cavitation is observed in the ordinary cavity. Although the cavitation cloud around the heat source is unfavorable for the heat transfer in the cavity with a focused ultrasonic field, the cavitations collapse and the resulting high temperature, higher pressure, and microjet effects still contribute substantially to heat transfer. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
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