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Sepsis is one of the most common causes of morbidity and mortality worldwide. Despite the remarkable advances in modern medicine throughout the last century, the mortality rates associated with sepsis have remained significantly elevated, both in high- and low-income countries. The main difficulty in the diagnosis and treatment of septic patients is the tremendous heterogeneity of this condition. The vast heterogeneity that characterizes sepsis ranges from the clinical presentation to the biological aspects of the disease. Evidence-based medicine approaches sepsis as a homogenous syndrome and does not consider the individual discrepancies between septic patients. This approach may contribute to the poor outcomes of septic patients. In recent years, personalized medicine has gained significant interest. This novel form of medicine underlines the importance of understanding the genetic, epigenetic, and molecular basis of a disease in order to provide a more tailored approach for the patient. The study of "omics", such as cytomics, genomics, epigenomics, transcriptomics, proteomics, and metabolomics, provides a deeper comprehension of the complex interactions between the host, the disease, and the environment. The aim of this review is to summarize the potential role of a personalized approach in sepsis management, considering the interactions between various "omics". [ABSTRACT FROM AUTHOR]

The role of social influence (SI) as a determining factor in accepting new technologies has been addressed in several studies using the initial or extended technology acceptance model (TAM). This research uses an adaptation of the extended technology acceptance model (TAM) to analyze the behavioral intention of Romanian consumers regarding the use of energy efficiency smart solutions (EESS) under the effect of social influence. Data were processed with the structural equation modeling technique (PLS-SEM). The sample consisted of 302 domestic electricity consumers in Romania. The study's findings show that the respondents' perceptions of the two social influence dimensions—network of friends, colleagues, or family (SI_FF); and public space (SI_PS)—and their effects on other conceptual model variables are significantly different. The main implications highlight that the proposed model addresses social influence on two levels (SI_FF and SI_PS), to highlight not only the differences in users' perceptions, but also the main directions in which efforts to promote these technologies should be focused more intensively, in the context of implementing European policies regarding the reduction of energy consumption at the level of household consumers. An important component of the proposed model is the analysis of the role of hedonic motivation constructs, expected performance, perceived usefulness, and perceived ease of use in mediating the relationship between social influence and behavioral intention to use. [ABSTRACT FROM AUTHOR]

The process audit is an analysis for the operation of an equipment, to establish its performance and to make proposals for measures to increase production, decrease consumption and improve product quality. The objective of the process audit is to establish the actual state of operation for the cement grinding plant (the degree of loading with grinding bodies, the air speed in the mill, the granulation of the material at the entrance and the exit, the wear of the shields, energy consumption) and is the basis for proposing measures for optimization. The audit from a grinding plant is carried out in the following situations: upon commissioning (to record the initial condition of the equipment) after modernization/modifications of the equipment in the composition of the grinding plant whenever there are deviations from the expected performance as a routine test, at least once a year, to appreciate the real condition of the equipment. The paper presents some determinations made at a cement mill from a Romanian cement factory, the sampling method to carry out analyses and recommendations for improving production. [ABSTRACT FROM AUTHOR]

The environmental changes are an important consequence of the negative impact of human activity. Companies are focusing more and more on developing sustainable practices, decreasing their waste and carbon emissions. Individuals have started to become more conscious about their consumption behaviors. In the last years, an increased level of spirituality is related with conscious behavior. Spiritual individuals have an enhanced level of empathy thus learning in their spiritual process to care more about the environment and other beings. Although the transformation regarding sustainability is visible, its rhythm is not fast enough to avoid significant damages on the planet. The main cause to this issue might be that consumers are not constant in their responsible behavior. We want to identify if individuals' behavior is due to the fear of judgement or out of consciousness about the beneficial impact on society. Therefore, we have created a questionnaire and distributed it randomly online on social media groups to discover what motivates individuals towards a sustainable conduct. The purpose of the article is to find out if individuals that pursue spiritual teachings or spirituality have a more sustainable behavior than individuals who do not. Is social media a beneficial source of information with regards to sustainability? This paper is helpful for people and companies who activate in the sustainability field and other related domains. [ABSTRACT FROM AUTHOR]

Team coordinators are prepared to manage multiple situations such as misunderstanding, conflicts, different levels of engagement and they are usually willing to take risks while accepting a leading position. Yet, not all of them are prepared for crisis such as COVID-19 pandemic. The way they communicate with their teams in this type of periods is essential to ensure continuity and establish organizational trust (Guzzo et al, 2021). In this context, many corporations had to face a new challenge: working mostly or even entirely from home. Employees as well as managers switched to virtual meetings, the concept of a team has suffered modifications and virtual meetings replaced all face-to-face interactions. Leaders had to adapt and learn how to improve their skills to engage with their teams and to ensure performance. The purpose of our study is to see what specific activities were implemented within teams while working from home, what is the perception leaders have about team performance and to find out if this context has diminished their level of control. Data for this paper are gathered using in-depth interviews with team leaders/coordinators/managers from different corporations installed in Bucharest, Romania. The results show that the performance has increased, the teams and coordinators showed a great adaptability, and their level of trust has improved. Recommendations are put forward for teams to consider creating a better balance between their personal and professional lives and to find new ways of socializing at work from time to time on other topics that the business-related ones. [ABSTRACT FROM AUTHOR]

Copyright of Transformations in Business & Economics is the property of Vilnius University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A great interest has developed over the last several years in research on interstitial Cajal-like cells (ICLCs), later renamed to telocytes (TCs). Such studies are restricted by diverse limitations. We aimed to critically review (sub)epicardial ICLCs/TCs and to bring forward supplemental immunohistochemical evidence on (sub)epicardial stromal niche inhabitants. We tested the epicardial expressions of CD117/c-kit, CD34, Cytokeratin 7 (CK7), Ki67, Platelet-Derived Growth Factor Receptor (PDGFR)-α and D2-40 in adult human cardiac samples. The mesothelial epicardial cells expressed D2-40, CK7, CD117/c-kit and PDGFR-α. Subepicardial D2-40-positive lymphatic vessels and isolated D2-40-positive and CK7-positive subepicardial cells were also found. Immediate submesothelial spindle-shaped cells expressed Ki-67. Submesothelial stromal cells and endothelial tubes were PDGFR-α-positive and CD34-positive. The expression of CD34 was pan-stromal, so a particular stromal cell type could not be distinguished. The stromal expression of CD117/c-kit was also noted. It seems that epicardial TCs could not be regarded as belonging to a unique cell type until (pre)lymphatic endothelial cells are inadequately excluded. Markers such as CD117/c-kit or CD34 seem to be improper for identifying TCs as a distinctive cell type. Care should be taken when using the immunohistochemical method and histological interpretations, as they may not produce accurate results. [ABSTRACT FROM AUTHOR]

Surrogacy, nowadays considered a form of assisted reproductive technology (ART), has historical roots that can be traced to ancient times. Although surrogacy is still the exception rather than the rule when it comes to ARTs, its rising popularity has attracted the curiosity and concerns of the media and society, who were unfamiliar with it beforehand. The advent of the first baby born after in vitro fertilization conception in 1978 offered many opportunities for infertile couples wanting a child of their own, one of which was the possibility of resorting to a gestational or traditional surrogate mother, instead of relying solely on adoption. The purpose of this article is to analyze the morality of surrogate motherhood through three apparently contrasting ethical theories: kantian deontology, utilitarianism, the rawlsian theory of justice. We will try to apply these concepts to three famous surrogacy cases and analyze their strong and weak points. [ABSTRACT FROM AUTHOR]

Nowadays, the use of smartphones has become essential for daily activities that have either a personal or professional purpose. A large number of resources is necessary for both the production and the use of these devices, which means that solutions in terms of sustainability are needed. The purpose of this research is to highlight the concept of sustainability when talking about smartphones, as well to underline the possibilities that exist for the consumers. This study examines the habits of young consumers in Romania, the reasons behind a mobile phone replacement, and the factors that influence the purchase decision. The methodology section follows quantitative and qualitative market research. An analysis was performed in order to have a deep understanding of trends in terms of mobile phone ownership and preferred brands. This study also provides a general view on the neglectfulness of the young population of Romania regarding the dangers to which the environment is exposed because of the purchasing habits that go against sustainability. For accomplishing this purpose, important results have been discovered through the analysis of the data obtained from self-administered questionnaires and interviews. The results show that people are usually using only one mobile phone at a time and they change it once every two years for sustainability and financial reasons. The same applies when it comes to choosing a certain brand. The reasons behind the purchase of a new phone and the decisions regarding an old one are based on healthy principles of the circular economy and sustainability. The preferences in terms of technology and design, and the decision process are correlated with incomes. [ABSTRACT FROM AUTHOR]

Copyright of Romanian Journal of Forensic Science is the property of Romanian Forensic Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)