1. Severe polymyositis due to Toxoplasma gondii in an adult immunocompetent patient: a case report and review of the literature.
- Author
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Cuomo, G., D'Abrosca, V., Rizzo, V., Nardiello, S., Montagna, G., Gaeta, G., and Valentini, G.
- Subjects
TOXOPLASMOSIS diagnosis ,ANTIMALARIALS ,SULFADIAZINE ,HEALTH outcome assessment ,POLYMYOSITIS ,TOXOPLASMOSIS ,TREATMENT effectiveness ,DISEASE complications ,THERAPEUTICS - Abstract
Toxoplasmosis, a worldwide zoonosis caused by a coccidian parasite Toxoplasma gondii, is more often asymptomatic in immunocompetent patients. We report the case of a 38-year-old immunocompetent male with a polymyositis as the presenting manifestation of T. gondii infection. The patient was hospitalized for a 30-day history of fever (T max 39.5°C), muscle pain, and progressive weakness of the muscles. A diagnosis of polymyositis was made, and he was started on corticosteroid treatment, which caused no reduction of symptoms. After finding a positive polymerase chain reaction (PCR) assay for T. gondii, together with additional clinical findings, a diagnosis of acute toxoplasmosis was made. Specific treatment with pyrimethamine and sulfadiazine was started, with a progressive reduction of symptoms and normalization of laboratory tests. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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