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Cobalt was commonly used as a colourant in the Egyptian glass industries of the 18th dynasty, dark blue glass being a regular find at palatial and settlement sites, including Amarna and Malqata. The main source of cobalt ore used during this period has been identified in the Egyptian western desert, around the oases of Kharga and Dakhla. In order to better understand the chaîne opératoire of Late Bronze Age glass production and -working, in particular with regard to cobalt ore, at Amarna, chemical analysis by portable X-Ray fluorescence was carried out in the field. This was done on contextualised archaeological material excavated at the site of Amarna, which cannot be exported from Egypt for analysis. The results of this study demonstrate how cobalt ore was used in the various known workshop sites at Amarna, resulting in a deeper understanding of raw materials use and exchange across this settlement. [ABSTRACT FROM AUTHOR]

Cobalt was commonly used as a colourant in the Egyptian glass industries of the 18th dynasty, dark blue glass being a regular find at palatial and settlement sites, including Amarna and Malqata. The main source of cobalt ore used during this period has been identified in the Egyptian western desert, around the oases of Kharga and Dakhla. In order to better understand the chaîne opératoire of Late Bronze Age glass production and -working, in particular with regard to cobalt ore, at Amarna, chemical analysis by portable X-Ray fluorescence was carried out in the field. This was done on contextualised archaeological material excavated at the site of Amarna, which cannot be exported from Egypt for analysis. The results of this study demonstrate how cobalt ore was used in the various known workshop sites at Amarna, resulting in a deeper understanding of raw materials use and exchange across this settlement. [ABSTRACT FROM AUTHOR]

The article discusses the archaeological excavation of a building complex in Tell e-Amarna, Egypt which used to house a glass and faience workshop. Topics discussed include the survey of the excavation area using magnetometry, glassworking-related objects found at the site, and the possible manufacture of glass and faience amulets and beads at the site as suggested by archaeological evidence.

Synaptic transmission depends on the regulated surface expression of neurotransmitter receptors, but many of the cellular processes required to achieve this remain poorly understood. To better define specific mechanisms for the GABAB receptor (GABABR) trafficking, we screened for proteins that bind to the carboxy-terminus of the GABAB1 subunit. We report the identification and characterization of a novel 130-kDa protein, GPCR interacting scaffolding protein (GISP), that interacts directly with the GABAB1 subunit via a coiled-coil domain. GISP co-fractionates with GABABR and with the postsynaptic density and co-immunoprecipitates with GABAB1 and GABAB2 from rat brain. In cultured hippocampal neurons, GISP displays a punctate dendritic distribution and has an overlapping localization with GABABRs. When co-expressed with GABABRs in human embryonic kidney cells, GISP promotes GABABR surface expression and enhances both baclofen-evoked extracellular signal-regulated kinase (ERK) phosphorylation and G-protein inwardly rectifying potassium channel (GIRK) currents. These results suggest that GISP is involved in the forward trafficking and stabilization of functional GABABRs. [ABSTRACT FROM AUTHOR]