1. The blood virome of 10,585 individuals from the ChinaMAP.
- Author
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Guo, Jia, Huang, Xuanlin, Zhang, Chenxi, Huang, Peide, Li, Yinhu, Wen, Fang, Wang, Xiaoji, Yang, Nanshan, Xu, Min, Bi, Yufang, Ning, Guang, Li, Lin, Wang, Weiqing, and Cao, Yanan
- Subjects
EPSTEIN-Barr virus ,MISSENSE mutation ,MEDICAL sciences ,ONCOGENIC viruses ,PROTEIN structure prediction - Abstract
We speculate that the I ACR i rs79314756 variant might enhance the activity of acrosin, thus facilitating the cleavage of C3 protein and promoting HHV6 virus transmission via the binding of membrane cofactor protein and oocyte receptors[13]. In addition, numerous common cancers are associated with oncogenic viruses, including Epstein-Barr virus (EBV), hepatitis B and C viruses (HBV and HCV), and human papillomavirus (HPV)[2]. These authors contributed equally: Jia Guo, Xuanlin Huang, Chenxi Zhang Dear Editor, Understanding the composition of human blood virome is essential for safe blood transfusions and infectious disease surveillance and control. Left: red bars represent the integration sites of HBV-B, and blue bars represent the integration sites of HBV-C. Right: the dark blue histogram represents the integration sites in HBV genome, and the light blue histogram represents the viral genome coverage. [Extracted from the article]
- Published
- 2022
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