12 results on '"Huang, Yitian"'
Search Results
2. Two-phase dual-signal-readout immunosensing platform based on multifunctional carbon nano-onions for ovarian cancer biomarker detection.
- Author
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Huang, Yitian, Zhang, Shupei, Chen, Yanjie, Gao, Lihong, Dai, Hong, and Lin, Yanyu
- Abstract
In order to detect early tumor markers and gain valuable time for treatment, there is an urgent need to develop a fast, cheap, and ultrasensitive multi-reading sensing platform. Herein, a solid/liquid two-phase dual-output biosensor was explored based on a sensitized sonochemiluminescence (SCL) strategy and a multifunctional carbon nano-onion (CNO) probe. It is clear that ultrasonic radiation caused the formation of hydroxyl radicals (˙OH), triggering the SCL signal of the emitter lucigenin (Luc
2+ ). Meanwhile, titanium carbide nanodots and ethanol were used to enhance the SCL signal, and an astonishingly linear enhancement of the SCL intensity was produced with increasing ethanol concentration. More importantly, the CNOs, with their excellent photothermal properties and adsorption capacity, can output both the temperature signal and an enhanced SCL strength from the solid–liquid phase. Through inter-calibration of the signals from the two-phases, this biosensor shows excellent analytical performance for the detection of the ovarian cancer biomarker, human epididymis-specific protein 4, from 10−5 to 10 ng mL−1 with a low detection limit of 3.3 fg mL−1 . This work not only provides a novel two-phase signal-output mode that broadens the scope of multiperformance joint applications of CNOs, but also enriches the quantitative detection of point-of-care testing. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
3. Photothermal enhanced fluorescence quenching of Tb-norfloxacin for ultrasensitive human epididymal 4 detection.
- Author
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Du, Lizhen, Chen, Yanjie, Huang, Yitian, Yan, Shanshan, Zhang, Shupei, and Dai, Hong
- Subjects
FLUORESCENCE quenching ,PHOTOTHERMAL effect ,CARBOXYMETHYLCELLULOSE ,COORDINATION polymers ,NORFLOXACIN ,BIOMOLECULES ,PHOTOTHERMAL conversion ,INTRAMOLECULAR proton transfer reactions ,CHEMORECEPTORS - Abstract
A fluorescence quenching enhanced immunoassay has been developed to achieve ultrasensitive recognition of human epididymal 4 (HE4) modifying the fluorescence quencher. The carboxymethyl cellulose sodium-functionalized Nb
2 C MXene nanocomposite (CMC@MXene) was firstly introduced to quench the fluorescence signal of the luminophore Tb-Norfloxacin coordination polymer nanoparticles (Tb-NFX CPNPs). The Nb2 C MXene nanocomposite as fluorescent nanoquencher inhibits the electron transfer between Tb and NFX to quench the fluorescent signal by coordinating the strongly electronegative carboxyl group on CMC with Tb (III) of Tb-NFX complex. Simultaneously, due to the superior photothermal conversion capability of CMC@MXene, the fluorescence signal has been further weakened by the photothermal effect driven non-radiative decay of the excited state under near-infrared laser irradiation. The constructed fluorescent biosensor based on CMC@MXene probe finally realized the enhanced fluorescence quenching effect, and achieved ultra-high sensitivity and selective detection of HE4, exhibiting a wide linear relationship with HE4 concentration on the logarithmic axis in the range of 10−5 to 10 ng/mL and a low detection limit of 3.3 fg/mL (S/N = 3). This work not only provides an enhanced fluorescent signal quenching method for the detection of HE4, but also provides novel insights for the design of fluorescent sensor toward different biomolecules. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
4. Dual-readout immunosensor based on multifunctional MXene probe triggers the signal amplification for detection of autoimmune hepatitis marker.
- Author
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Liu, Sha, Li, Xiaofeng, Chen, Yanjie, Huang, Yitian, Zhang, Shupei, and Dai, Hong
- Subjects
AUTOIMMUNE hepatitis ,SIGNAL detection ,PHOTOTHERMAL conversion ,THERMORESPONSIVE polymers ,STERIC hindrance ,ACRYLAMIDE - Abstract
A dual-readout immunosensor coupled with electrochemical impedance and temperature signal was successfully proposed to detect autoimmune hepatitis markers (ASGPR). Nb
2 C MXene with excellent conductivity, abundant surface functional groups, and extraordinary photothermal conversion efficiency, was designed to be a multifunctional biological probe, whose specific binding with antigen enhanced steric hindrance to generate electrochemical impedance signal, and at the same time, it had a strong optical response in the near-infrared band to achieve temperature output. In addition, poly(N-isopropyl acrylamide) (PNIPAM) was a temperature-sensitive polymer, which was adopted as the sensing matrix. When the multifunctional probe was specifically bound to the antigen, under 808-nm laser irradiation, the captured Nb2 C MXene achieved photothermal conversion to increase the electrode surface temperature, and the conformation of PNIPAM changed from a free spiral to a spherical shape, further realizing double amplification of the EIS signal. Under the optimized experimental conditions, the impedance values and the temperature changes increased proportionally with the increase of the ASGPR concentration from 10−5 to 1 ng/mL, and the detection limit of the immunosensor was 3.3 × 10−6 ng/mL. The established dual-readout immunosensor exhibited good selectivity and acceptable stability and provided an effective detection method for autoimmune hepatitis marker detection. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
5. Chinese ENGOs and the Heavy-Metal Pollution of the Consumer-Electronics Industry: Exploring the Constraining Factors.
- Author
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Huang, Yitian
- Subjects
INDUSTRIAL pollution ,LOCAL government ,HUMAN resources departments ,CONFLICT of interests ,MASS media ,PARTICIPATION - Abstract
The heavy-metal pollution of the consumer-electronics industry has been a serious environmental problem in China. Since 2010, Chinese ENGOs have taken a few measures to address this challenge. Under the influence of other stakeholders, Chinese ENGOs have only played a limited role. To further explore the potential of domestic ENGOs, it would be necessary to understand how they have approached the heavy-metal challenge and why their contribution has been moderate. By using the method of "process tracing," this paper presents a preliminary attempt to trace and generate localized knowledge of Chinese ENGOs' approach and the influence of other stakeholders. Specifically, this paper divides the actions of Chinese ENGOs into the following three phases: initial participation, progressive involvement of MNCs, and collaborative tracking and online disclosure. Then, it traces the participation of Chinese mass media, domestic suppliers, local governments, and communities. It argues that the following six constraining factors have contributed to shaping the limited role of those Chinese ENGOs: (1) the complexity of the consumer-electronics supplier network; (2) Chinese ENGOs' lack of leverage on MNCs; (3) Chinese ENGOs' shortage of financial and human resources under a broad agenda; (4) domestic mass media's lack of long-term interest; (5) reluctant participation of Chinese suppliers and local governments; and (6) conflicting interests within local communities. Three policy options for further exploring the potential of Chinese ENGOs are discussed, including financial and technical support, further engagement of international ENGOs, and supportive policy-making and interregional coordination by local governments. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
6. Dual-readout proximity hybridization-regulated and photothermally amplified protein analysis based on MXene nanosheets.
- Author
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Ren, Huizhu, Zhang, Shupei, Huang, Yitian, Chen, Yanjie, Lv, Liang, and Dai, Hong
- Subjects
PROTEIN analysis ,PHOTOTHERMAL effect - Abstract
Herein, an ingenious dual-readout sensing platform based on a proximity hybridization-regulated strategy is proposed for protein detection. For the first time, Ti
3 C2 MXene@thionine composites (MXene@Thi) with an excellent photothermal effect not only acted as an amplifier to enhance the electrochemical signal, but were also used as a converter to achieve the temperature readout. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
7. Multi-Level Governance: Explaining the "climate-focused" behavior of Chinese exporting companies.
- Author
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Huang, Yitian
- Subjects
MULTI-level governance (Theory) ,EXPORT trading companies ,BUSINESS planning ,ENVIRONMENTAL responsibility ,CLIMATE change mitigation - Abstract
While being increasingly aware of the importance of adopting climate-friendly business strategies, Chinese exporting companies have been active in taking "climate-related" actions but moderate in taking "climate-focused" actions. This article presents a preliminary attempt to apply Multi-Level Governance theories to explain the behavior of Chinese exporting companies toward climate change mitigation. It argues that the convergence of state-centered climate politics and market-oriented climate governance, which has a multi-level feature, has shaped the "climate-focused" behavior of Chinese exporting companies. Specifically, nation-states, multinational enterprises, and non-governmental organizations have contributed in the following ways: (1) at the global level, nation-states co-established and interpreted international norms, which generally justify the stance of the Chinese government, have been an indirect source of influence; (2) at the national level, the Chinese government has been the most influential actor, which has put emphasis on energy-saving when interpreting and operationalizing international norms; (3) at the industrial level, multinational enterprises and international non-governmental organizations have been influential contributors by playing a proactive role in launching and running low-carbon initiatives; and (4) transnational public–private partnerships launched in China and some developed countries have offered limited momentum. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
8. The Role of ENGOs in Greening Consumer Electronics Supply Chains in China: The Case of Heavy Metal Pollution.
- Author
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Huang, Yitian
- Published
- 2017
- Full Text
- View/download PDF
9. The prospect of engaging China in the ICAO global MBM scheme.
- Author
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Huang, Yitian
- Subjects
AIRLINE industry ,AIRLINE industry & the environment ,ENERGY consumption ,EMISSIONS (Air pollution) ,EMISSION exposure - Published
- 2017
- Full Text
- View/download PDF
10. Foreign policy ‘trilemmas’: understanding China's stance on international cap-and-trade.
- Author
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Huang, Yitian and Bailis, Rob
- Subjects
INTERNATIONAL relations ,COMMERCIAL aeronautics ,PRIVATE flying ,FLEXIBILITY (Mechanics) ,FOREIGN exchange - Abstract
This article uses a policy analogy approach to explore China's attitude toward the possibility of global carbon market integration, including the development of a common cap-and-trade market for the global civil aviation industry. Like in other foreign policy domains, in international cap-and-trade, China faces a ‘trilemma’ between carbon market integration, state sovereignty and policy flexibility. By referring to how China has approached a comparable trilemma in foreign exchange policy making, we analyse China's possible stance on international cap-and-trade. We argue that China will prefer to gradually establish and strengthen, to a limited extent, intergovernmental governance mechanisms, which allow nation-states to prioritize sovereignty and policy flexibility in carbon trading policy making. In the conclusion we use this argument to explain China's responses to the carbon-trading initiatives of Australia, the EU, the International Civil Aviation Organization (ICAO), and the World Bank. Policy relevance The international community has reached a consensus on the use of market mechanisms for mitigating climate change. While opposing the EU's plan to include Chinese airlines in the EU Emissions Trading Scheme, China has started to co-explore with Australia the possibility of linking their carbon markets, and has adopted a supportive attitude toward the carbon trading initiatives led by the ICAO and the World Bank. Considering China's status as the largest emitting country of GHGs and its interdependence with major developed and developing countries, China's substantial participation would be crucial to the success of the global market-based efforts to reduce GHG emissions. This article presents an initial attempt to develop a better understanding of China's stance on international cap-and-trade. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
11. Combustion Stability of Low Calorific Gas in Porous Media without Pre-Mixer.
- Author
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Li, Juntao, Wang, Guanqing, Huang, Hua, Xu, Bingjie, and Huang, Yitian
- Abstract
Preliminary experiments were done to investigate the combustion characteristics of low calorific gas in porous media without pre-mixer. Ignition start-up process was discussed at the certain operating parameters. Temperature profiles stability was analyzed in details between extreme low equivalence ratio (LER) and high equivalence ratio (HER), in addition the combustion emission. The results showed that stable ignition and combustion in porous media without pre-mixer can be obtained. The structure and arrangement style of foam ceramics have much influence on flame stabilization. Combustion flame stabilizes at upstream of combustor atφ0.45; Temperature profile is more stable at relative HER than that of LER; stable combustion wave is formed at LER. Stable emission can be obtained at certain operating conditions. [ABSTRACT FROM PUBLISHER]
- Published
- 2012
- Full Text
- View/download PDF
12. Policy Experimentation and the Emergence of Domestic Voluntary Carbon Trading in China.
- Author
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Huang, Yitian
- Subjects
CARBON offsetting ,CARBON dioxide mitigation ,EMISSION control ,EMISSIONS trading ,NON-state actors (International relations) ,CHINESE politics & government, 1949- ,SOCIAL conditions in China, 1949- - Abstract
As China has become the largest greenhouse gas (GHG) emitter in terms of total annual emissions, to promote GHG emissions reduction in China turns out to be crucial to the success of the global efforts to address climate change. This paper explores the development of the Chinese Domestic Voluntary Carbon Market (DVCM) in order to understand how carbon trading institutions have emerged and developed in China. To do this, it traces and analyzes the roles of the Chinese government and other key actors. Through process tracing and literature review, it argues that the pre-legislation and territorially fragmented development pattern of the Chinese DVCM has resulted from the activities of Chinese local governments and non-state actors under the policy experimentation approach adopted by the Chinese central government. It concludes with brief comments on the Chinese policy experimentation approach, and suggests that some measures can be taken to promote voluntary emissions reduction and policy learning. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
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