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This study is intended to provide insight into geospatial practitioners' viewpoints toward the US Department of Labor, Employment and Training Administration (DOLETA) Geospatial Technology Competency Model (GTCM). These viewpoints are significant since business professionals use workplace competencies for job analysis, professional certification, and defining workforce requirements. The research sought to determine the views held toward a set of geospatial competencies and provide the field with an understanding of how practitioners perceive these competency statements. Sixty‐one participants sorted 42 cards (with geospatial competency statements) on a scale of −5 to 5 and completed two short surveys with demographic and open‐ended questions. The data were evaluated using factor analysis, descriptive statistics, and a combination of high, low, and distinguishing statements to provide meaning to the viewpoints. [ABSTRACT FROM AUTHOR]

We provide body measurements of snow leopards collected from 55 individuals sampled in five of the major mountain ranges within the species distribution range; the Altai, Hindu Kush, Himalayas, Pamirs and Tien Shan mountains. Snow leopards appear to be similarly sized across their distribution range with mean body masses of 36 kg and 42 kg for adult females and adult males, respectively. In contrast to other large felids, we found little variation in body size and body mass between the sexes; adult males were on average 5% longer and 15% heavier than adult females. [ABSTRACT FROM AUTHOR]

We report for the first time the occurrence of an Eutypella species on cotton in New South Wales (NSW), Australia. The putative Eutypella was isolated from dead cotton plants that exhibited atypical symptoms of either Fusarium or Verticillium wilt. Dead plants had symptoms resembling lightning strike damage with blackened outer bark around the fifth node zone. Internal vascular discoloration was reddish grey and often occurred in V-shaped sections. Sequences of the internal transcribed spacer (ITS) revealed a 93.7–94.1% similarity to Eutypella scoparia, indicating that the NSW cotton isolates represented a putatively novel species within the Eutypella genus. Pathogenicity of the isolated Eutypella was assessed on cotton stem cuts and living plants inoculated with culture agar plugs. Typical black necroses on outer bark and reddish vascular discoloration were reinduced in both Eutypella-inoculated stem cuts and living plants. Subsequently, the same Eutypella pathogen was successfully recovered, thus fulfilling Koch's postulates. The detection of Eutypella on NSW cotton is believed to be an independent event from a recently reported occurrence of Eutypella on Queensland cotton. The Queensland detection occurred in the same 2017/18 cropping season at approximately 730 km apart and was associated with distinct Eutypella isolates. [ABSTRACT FROM AUTHOR]

Understanding landscape connectivity and population genetic parameters is imperative for threatened species management. However, such information is lacking for the snow leopard (Panthera uncia). This study sought to explore hierarchical snow leopard gene flow patterns and drivers of genetic structure in Mongolia and China. A total of 97 individuals from across Mongolia and from the north-eastern edge of the Qinghai-Tibetan Plateau in Gansu Province to the middle of Qinghai Province in China were genotyped across 24 microsatellite loci. Distance-based frameworks were used to determine a landscape scenario best explaining observed genetic structure. Spatial and non-spatial methods were used to investigate fine-scale autocorrelation and similarity patterns as well as genetic structure and admixture. A genetic macro-division between populations in China and Mongolia was observed, suggesting that the Gobi Desert is a substantial barrier to gene flow. However, admixture and support for a resistance-based mode of isolation suggests connective routes that could facilitate movement. Populations in Mongolia had greater connectivity, indicative of more continuous habitat. Drivers of genetic structure in China were difficult to discern, and fine-scale sampling is needed. This study elucidates snow leopard landscape connectivity and helps to prioritize conservation areas. Although contact zones may have existed and occasional crossings can occur, establishing corridors to connect these areas should not be a priority. Focus should be placed on maintaining the relatively high connectivity for snow leopard populations within Mongolia and increasing research efforts in China. [ABSTRACT FROM AUTHOR]

Cotton (Gossypium hirsutum) is a billion-dollar crop in regional New South Wales (NSW) and Queensland, Australia. Fusarium wilt (FW) caused by Fusarium oxysporum f. sp. vasinfectum (Fov) is an economically important disease. Initial disease losses of up to 90% when the disease was first detected resulted in fields being taken out of cotton production. The disease is now well-managed due to the adoption of highly resistant varieties. However, annual disease surveys recently revealed that the disease dynamic has changed in the past few seasons. With relatively mild and wet weather conditions during the 2021/22 growing season, FW was detected in eight surveyed valleys in NSW and Queensland, with the disease incidence as high as 44.5% and 98.5% in individual fields in early and late seasons, respectively. Fov is genetically distinct and evolved from local Fusarium oxysporum strains. Additionally, the pathogen was reported to evolve rapidly under continuous cotton cropping pressure. However, our knowledge of the genetic composition of the prevailing population is limited. Sequences of the translation elongation factor alpha 1 (TEF1) revealed that 94% of Fusarium isolates recovered from FW-infected cotton were clustered together with known Australian Fov and relatively distant related to overseas Fov races. All these isolates, except for nine, were further confirmed positive with a specific marker based on the Secreted in Xylem 6 (SIX6) effector gene. Vegetative compatibility group (VCG) analyses of 166 arbitrarily selected isolates revealed a predominance of VCG01111. There was only one detection of VCG01112 in the Border Rivers valley where it was first described. In this study, the exotic Californian Fov race 4 strain was not detected using a specific marker based on the unique Tfo1 insertion in the phosphate (PHO) gene. This study indicated that the prevalence and abundance of Fov across NSW and Queensland in the past five seasons was probably independent of its genetic diversity. [ABSTRACT FROM AUTHOR]

Black root rot disease of cotton seedlings caused by Thielavioposis basicola was first reported in New South Wales (NSW), Australia in 1990. In 2018, T. basicola was reclassified into a new genus Berkeleyomyces, accommodating two closely related species: B. basicola and B. rouxiae. However, species status of cotton-T. basicola in NSW remains unsolved. Ninety-five isolates recovered from black root rot diseased cotton seedlings sampled across NSW in 2017/18 season was subjected to morphological, multigene sequencing (ITS, MCM7, RPB2), and pathogenicity assessments for their species identification. Berkeleyomyces rouxiae was accurately identified as the causal agent of black root rot of cotton. [ABSTRACT FROM AUTHOR]

This study was undertaken in spring, 2019 to assess the applicability of the double-observer survey method for estimating blue sheep Pseudois nayaur abundance in Nar-Phu valley of Manang District located in Annapurna Conservation Area of northern Nepal. Since counting large mammals in rugged mountain habitat poses a special challenge, we tested the efficacy of the double observer method for generating robust population estimates for this important protected area. The overall detection probability for observers (O1 and O2) was 0.94 and 0.91 for a total of 106 groups comprised of 2059 individual blue sheep. We estimated the area's blue sheep population at 2070 (SE ± 168.77; 95% CI 2059–2405) for the 246.2 km2 of sampled habitat. We determined blue sheep to be widely distributed within the study area with a mean density of 8.4 individuals per km2 based on a total study area of 246.2 km2. We discuss demographic population structure and identify limitations when applying the double observer approach, along with recommending viewshed mapping for ensuring more robust density estimates of mountain-dwelling ungulates like blue sheep or ibex that inhabit extremely heterogeneous terrain which strongly influences sighting distances and overall animal detection rates. [ABSTRACT FROM AUTHOR]

Application of next-generation sequencing (NGS) to DNA metabarcoding can greatly increase the understanding of predator–prey dynamics and the conflict between wildlife and humans, but remains underutilized for carnivores such as the threatened snow leopard (Panthera uncia). To date, this technique was hindered by the difficulty in discerning closely related caprines (Caprinae). We identified a segment of mitochondrial cytochrome c oxidase subunit 1 (MT-CO1) to differentiate these prey, and used this marker in tandem with a portion of mitochondrial 12S rRNA (MT-RNR1) to determine dietary items in 165 genetically confirmed snow leopard scats from four range countries. Identified prey species consisted of ten medium to large mammals, three small mammals, and two birds. The dominant prey consumed varied by country, with markhor (Capra falconeri) most prevalent in Pakistan, Siberian ibex (C. sibirica) in Mongolia and Kyrgyzstan, and blue sheep (Pseudois nayaur) in China. Livestock comprised 31% of diet occurrences from Pakistan and 15% from Mongolia. Domestic livestock included goat (C. aegagrus hircus), sheep (Ovis aries), bovids (Bos taurus, B. grunniens, and potentially hybrids), and horse (Equus caballus). Protection and management of regionally specific wild prey is crucial for sustaining snow leopard populations, although overall dietary breadth suggests that snow leopards may exploit other species if necessary, including livestock. Additional sampling efforts across seasons, years, regions, and areas with varying degrees of livestock depredation are needed. MT-CO1 in conjunction with MT-RNR1 can be applied to other carnivore diet studies, making it an important tool for conservation and research, particularly in ecosystems with pastoral communities. [ABSTRACT FROM AUTHOR]

Cotton is a billion-dollar crop in Australia, especially in the regional areas of New South Wales (NSW) and Queensland. Fusarium wilt caused by Fusarium oxysporum f. sp. vasinfectum (Fov) is of an important disease on cotton globally and in Australia. The Australian cotton industry is currently adopting highly resistant cultivars to Fov. Therefore, it is expected that Fusarium wilt pressure will be minimal on the cotton crop. However, we recovered a total of 186 putative Fusarium isolates from cotton seedlings exhibiting atypical symptoms of either Fusarium damping-off or Fusarium wilt sampled across NSW during the 2017/18 and 2018/19 seasons. On a basis of sequence analysis of the translation elongation factor 1-alpha (TEF1), eight Fusarium species were identified that being Fusarium oxysporum and F. equiseti species complex, F. falciforme, F. nygamai, F. brachygibbosum, F. acuminatum, F. chlamydosporum, and F. redolens. Of these, F. oxysporum species complex (FOSC) accounted for over 80% of the total number of isolates recovered. The predominant number of isolates (78.5%) were clustered with non-Australian Fov races 1–8. The remaining 21.5% of the FOSC isolates in our study was clustered with the Australian Fov biotypes, a unique phylogenetic group within the FOSC. Our study is the first TEF1-based assessment of Fusarium diversity associated with collar rot diseased cotton seedlings sampled across NSW, Australia. [ABSTRACT FROM AUTHOR]

The existence of a trans‐boundary population of the snow leopard (Panthera uncia) that inhabits the massifs of Tsagaanshuvuut (Mongolia) – Tsagan‐Shibetu (Russia) was determined through non‐invasive genetic analysis of scat samples and by studying the structure of territory use by a collared female individual. The genetic analysis included species identification of samples through sequencing of a fragment of the cytochrome b gene and individual identification using a panel of 8 microsatellites. The home range of a female snow leopard marked with a satellite Global Positioning System (GPS) collar was represented by the minimum convex polygon method (MCP) 100, the MCP 95 method and the fixed kernel 95 method. The results revealed insignificant genetic differentiation between snow leopards that inhabit both massifs (minimal fixation index [FST]), and the data testify to the unity of the cross‐border group. Moreover, 5 common individuals were identified from Mongolian and Russian territories. This finding clearly shows that their home range includes territories of both countries. In addition, regular movement of a collared snow leopard in Mongolia and Russia confirmed the existence of a cross‐border snow leopard group. These data support that trans‐boundary conservation is important for snow leopards in both countries. We conclude that it is crucial for Russia to study the northern range of snow leopards in Asia. [ABSTRACT FROM AUTHOR]

Objectives: Recent studies in acute coronary syndrome (ACS) have reported mixed results for trends in ACS subtypes. The All New Zealand Acute Coronary Syndrome Quality Improvement (ANZACS-QI) 31 study evaluated trends in ACS event rates, invasive management and mortality of ST-elevation myocardial infarction (STEMI), non-STEMI (NSTEMI) and unstable angina (UA) in New Zealand.Methods: All ACS hospitalisations between 2006 and 2016 were identified from routinely collected national data and categorised into STEMI, NSTEMI, UA and MI unspecified (MIU). Annual hospitalisation, coronary procedure, 28-day and 1-year mortality rates were calculated and trends tested using Poisson regression adjusting for age and sex.Results: Over the 11-year study period, there were 188 264 ACS admissions, of which 16.0% were STEMI, 54.5% NSTEMI, 25.7% UA and 3.8% MIU. Event rates of all ACS subtypes fell: STEMI by 3.4%/year, NSTEMI by 5.9%/year and UA by 8.5%/year, while the proportion of patients with ACS receiving angiography and revascularisation increased by 5.6% per year. Rates of percutaneous coronary intervention rose for STEMI, NSTEMI and UA, but coronary artery bypass grafting increased only for NSTEMI and UA. Mortality at 28 days and 1 year was higher for STEMI than NSTEMI and lowest for UA. There was a relative 1.6%/year decline in 1 year mortality for NSTEMI (p<0.001), but no significant change for STEMI and UA.Conclusions: We observed declines in the event rates of all ACS subtypes and increases in revascularisation rates. The finding that mortality declined in patients with NSTEMI, but not in patients with STEMI and UA, despite increases in invasive procedures, requires further investigation. [ABSTRACT FROM AUTHOR]

Background: Clinical practice guidelines have traditionally recommended blood pressure treatment based primarily on blood pressure thresholds. In contrast, using predicted cardiovascular risk has been advocated as a more effective strategy to guide treatment decisions for cardiovascular disease (CVD) prevention. We aimed to compare outcomes from a blood pressure-lowering treatment strategy based on predicted cardiovascular risk with one based on systolic blood pressure (SBP) level.Methods and Findings: We used individual participant data from the Blood Pressure Lowering Treatment Trialists' Collaboration (BPLTTC) from 1995 to 2013. Trials randomly assigned participants to either blood pressure-lowering drugs versus placebo or more intensive versus less intensive blood pressure-lowering regimens. We estimated 5-y risk of CVD events using a multivariable Weibull model previously developed in this dataset. We compared the two strategies at specific SBP thresholds and across the spectrum of risk and blood pressure levels studied in BPLTTC trials. The primary outcome was number of CVD events avoided per persons treated. We included data from 11 trials (47,872 participants). During a median of 4.0 y of follow-up, 3,566 participants (7.5%) experienced a major cardiovascular event. Areas under the curve comparing the two treatment strategies throughout the range of possible thresholds for CVD risk and SBP demonstrated that, on average, a greater number of CVD events would be avoided for a given number of persons treated with the CVD risk strategy compared with the SBP strategy (area under the curve 0.71 [95% confidence interval (CI) 0.70-0.72] for the CVD risk strategy versus 0.54 [95% CI 0.53-0.55] for the SBP strategy). Compared with treating everyone with SBP ≥ 150 mmHg, a CVD risk strategy would require treatment of 29% (95% CI 26%-31%) fewer persons to prevent the same number of events or would prevent 16% (95% CI 14%-18%) more events for the same number of persons treated. Compared with treating everyone with SBP ≥ 140 mmHg, a CVD risk strategy would require treatment of 3.8% (95% CI 12.5% fewer to 7.2% more) fewer persons to prevent the same number of events or would prevent 3.1% (95% CI 1.5%-5.0%) more events for the same number of persons treated, although the former estimate was not statistically significant. In subgroup analyses, the CVD risk strategy did not appear to be more beneficial than the SBP strategy in patients with diabetes mellitus or established CVD.Conclusions: A blood pressure-lowering treatment strategy based on predicted cardiovascular risk is more effective than one based on blood pressure levels alone across a range of thresholds. These results support using cardiovascular risk assessment to guide blood pressure treatment decision-making in moderate- to high-risk individuals, particularly for primary prevention. [ABSTRACT FROM AUTHOR]

Assessments of biodiversity status are needed to track trends, and the IUCN Red List has become the accepted global standard for documenting the extinction risk of species. Obtaining robust data on population size is an essential component of any assessment of a species’ status, including assessments for the IUCN Red List. Obtaining such estimates is complicated by methodological and logistical issues, which are more pronounced in the case of cryptic species, such as the snow leopard Panthera uncia. Estimates of the total population size of this species have, to date, been based on little more than guesstimates, but a comprehensive summary of recent field research indicates that the conservation status of the snow leopard may be less dire than previously thought. A revised categorization, from Endangered to Vulnerable, on the IUCN Red List was proposed but met some opposition, as did a recent, similar recategorization of the giant panda Ailuropoda melanoleuca. Possible factors motivating such attitudes are discussed. Downlisting on the IUCN Red List indicates that the species concerned is further from extinction, and is always to be welcomed, whether resulting from successful conservation intervention or improved knowledge of status and trends. Celebrating success is important to reinforce the message that conservation works, and to incentivize donors. [ABSTRACT FROM AUTHOR]

Over the past decade important advances have been made toward addressing human-wildlife conflict associated with the endangered snow leopard (Panthera uncia). Engaging and motivating stakeholders through more participatory protocols remains a vital ingredient toward the design, implementation, and of monitoring robust, long-lasting, and locally adapted solutions that stress the community's collective and positive visions for the change. Co-existence with this predator can be best achieved by empowering rural communities and helping them forge more harmonious and eco-centric relationships with their environment, one in which snow leopards are perceived as valued assets rather than pests to be eliminated. The Global Snow Leopard Environmental Plan endorsed in 2013 by all 12 snow leopard range countries offers a possible blueprint for this transformational process to take place. The major challenge rests with securing the necessary financing and the scaling up of remedial interventions to landscape levels across the range states. [ABSTRACT FROM AUTHOR]

Over the past decade important advances have been made toward addressing human-wildlife conflict associated with the endangered snow leopard (Panthera uncia). Engaging and motivating stakeholders through more participatory protocols remains a vital ingredient toward the design, implementation, and of monitoring robust, long-lasting, and locally adapted solutions that stress the community's collective and positive visions for the change. Co-existence with this predator can be best achieved by empowering rural communities and helping them forge more harmonious and eco-centric relationships with their environment, one in which snow leopards are perceived as valued assets rather than pests to be eliminated. The Global Snow Leopard Environmental Plan endorsed in 2013 by all 12 snow leopard range countries offers a possible blueprint for this transformational process to take place. The major challenge rests with securing the necessary financing and the scaling up of remedial interventions to landscape levels across the range states. [ABSTRACT FROM AUTHOR]

Molecular markers that can effectively identify noninvasively collected samples and provide genetic information are critical for understanding the distribution, status, and ecology of snow leopards ( Panthera uncia). However, the low DNA quantity and quality in many noninvasive samples such as scats makes PCR amplification and genotyping challenging. We therefore designed primers for 9 microsatellites loci previously isolated in the domestic cat ( Felis catus) specifically for snow leopard studies using noninvasive samples. The loci showed moderate levels of variation in two Mongolian snow leopard populations. Combined with seven other loci that we previously described, they have sufficient variation (H = 0.504, A = 3.6) for individual identification and population structure analysis. We designed a species-specific PCR assay using cytochrome b for identification of unknown snow leopard samples. These molecular markers facilitate in depth studies to assess distribution, abundance, population structure, and landscape connectivity of this endangered species. [ABSTRACT FROM AUTHOR]

We conducted a status-survey on Snow Leopard Panthera uncia and its main prey, the Blue Sheep Pseudois nayaur, in the Mustang District of Nepal's Annapurna Conservation Area, in 2010 and 2011. Sign transects, covering a total linear distance of 19.4km, revealed an average density of 5.8 signs per kilometer, which compares with those from other Snow Leopard range countries. This also roughly corresponded with the minimum number of three adult Snow Leopards we obtained from nine remote cameras, deployed to monitor areas of c. 75km2 in extent. We obtained 42 pictures of Snow Leopards during nine capture events. We conclude that Mustang harbors at least three adult Snow Leopards, and probably more, along with a healthy Blue Sheep population (a total of 528 individuals, along 37.6km of Snow Leopard transect lines). We suggest that people-wildlife conflicts exist but that the local people tolerate Snow Leopards based on their Buddhist socio-religious values. [ABSTRACT FROM AUTHOR]

While the world is becoming increasingly interconnected and interdependent, physically and culturally, the wildlife of remote mountain regions is being affected both positively and negatively by such interconnectedness. In the case of snow leopards, the conservation impact has been largely, and rather unexpectedly, positive: Species-focused conservation projects, such as Project Snow Leopard (PSL) in Gilgit-Baltistan, remain mainly externally driven initiatives. PSL, initiated as a small pilot project in 1998, has relied on an approach that includes the use of an insurance scheme, the deployment of mitigation measures, and the empowerment of local governance. This approach has been successful in reducing the conflict with snow leopards and has built greater tolerance toward them. PSL is managed by local communities and cofinanced by them. PSL communities throughout the region are bearing the burden of carnivore conservation, and they are unwittingly subsidizing their populations by ''feeding'' them their livestock even though they are an economic threat to them. In this article, we argue that external intervention in the form of efforts that help alleviate the consequences of conflict through local empowerment have had a positive impact on the local mountain societies. We also show that such interventions have resulted in tangible conservation results, with the number of snow leopards staying at least stable. Our experience also shows that while the incentive component is critical, it is also part of a larger approach--one that includes developing and supporting local governance structures, improving access to education, and offering a range of tools to reduce the conflict that can be implemented locally. Finally, we suggest that investing in this approach-- one that recognizes the species and local-context complexities surrounding the implementation of conservation incentives--can continue to inform international practices and guidelines for reducing human-wildlife conflicts worldwide. INSET: How the insurance scheme works. [ABSTRACT FROM AUTHOR]

The endangered snow leopard (Panthera uncia) is widely but sparsely distributed throughout the mountainous regions of central Asia. Detailed information on the status and abundance of the snow leopard is limited because of the logistical challenges faced when working in the rugged terrain it occupies, along with its secretive nature. Camera-trapping and noninvasive genetic techniques have been used successfully to survey this felid. We compared noninvasive genetic and camera-trapping snow leopard surveys in the Gobi Desert of Mongolia. We collected 180 putative snow leopard scats from 3 sites during an 8-day period along 37.74 km of transects. We then conducted a 65-day photographic survey at 1 of these sites, approximately 2 months after scat collection. In the site where both techniques were used noninvasive genetics detected 5 individuals in only 2 days of fieldwork compared to 7 individuals observed in the 65-day camera-trapping session. Estimates of population 2 size from noninvasive genetics ranged between 16 and 19 snow leopards in the 314.3-km² area surveyed, 2 yielding densities of 4.9-5.9 individuals/100 km². In comparison, the population estimate from the 65-day 2 photographic survey was 4 individuals (adults only) within the 264-km² area, for a density estimate of 1.5 snow 2 leopards/100 km². Higher density estimates from the noninvasive genetic survey were due partly to an inability to determine age and exclude subadults, reduced spatial distribution of sampling points as a consequence of collecting scats along linear transects, and deposition of scats by multiple snow leopards on common sites. Resulting differences could inflate abundance estimated from noninvasive genetic surveys and prevent direct comparison of densities derived from the 2 approaches unless appropriate adjustments are made to the study design. [ABSTRACT FROM AUTHOR]

Previous research has reported a protective association between alcohol drinking and acute coronary heart disease in the 24-hour period after drinking. This study investigated whether this apparent protective association resulted from confounding due to the effect of prodromal symptoms on drinking behavior. In 1992, the authors conducted a case-control study that measured recent alcohol consumption and reasons for recent abstention from alcohol among patients with acute coronary heart disease identified from a community-based disease register and a representative control sample from the same community (Auckland, New Zealand). Cases were significantly more likely than controls to report recent abstention from drinking because they felt unwell. In unadjusted analyses, a protective association was observed between recent alcohol consumption and acute coronary heart disease; however, this association was weakened considerably after adjustment for the effect of prodromal symptoms on drinking behavior. The previously reported protective association between recent alcohol consumption and acute coronary heart disease appears to be largely due to the confounding effect of prodromal symptoms on drinking. Am J Epidemiol 2000; 151: 1189-93. [ABSTRACT FROM PUBLISHER]

This population-based case-control study investigated associations between prostate cancer risk and dietary intake of the carotenoids β-carotene and lycopene and their major plant food sources, including carrots, green leafy vegetables, and tomato-based foods. The study was carried out in Auckland, New Zealand, during 1996–1997 and recruited 317 prostate cancer cases and 480 controls. The authors found that dietary intake of β-carotene and its main vegetable sources was largely unassociated with prostate cancer risk, whereas intake of lycopene and tomato-based foods was weakly associated with a reduced risk. These results suggest that in contrast to the findings regarding many types of cancers, vegetables rich in β-carotene are not protective against prostate cancer. However, lycopene from tomato-based foods was found to be associated with a small reduction in risk. Am J Epidemiol 2000; 151:119-23. [ABSTRACT FROM PUBLISHER]

Conservation and management of snow leopards (Uncia uncia) has largely relied on anecdotal evidence and presence-absence data due to their cryptic nature and the difficult terrain they inhabit. These methods generally lack the scientific rigor necessary to accurately estimate population size and monitor trends. We evaluated the use of photography in capture-mark-recapture (CMR) techniques for estimating snow leopard population abundance and density within Hemis National Park, Ladakh, India. We placed infrared camera traps along actively used travel paths, scent-sprayed rocks, and scrape sites within 16- to 30-km² sampling grids in successive winters during January and March 2003-2004. We used head-on, oblique, and side-view camera configurations to obtain snow leopard photographs at varying body orientations. We calculated snow leopard abundance estimates using the program CAPTURE. We obtained a total of 66 and 49 snow leopard captures resulting in 8.91 and 5.63 individuals per 100 trap-nights during 2003 and 2004, respectively. We identified snow leopards based on the distinct pelage patterns located primarily on the forelimbs, flanks, and dorsal surface of the tail. Capture probabilities ranged from 0.33 to 0.67. Density estimates ranged from 8.49 (SE = 0.22) individuals par 100 km² in 2003 to 4.45 (SE = 0.16) in 2004. We believe the density disparity between years is attributable to different trap density and placement rather than to an actual decline in population size. Our results suggest that photographic capture-mark-recapture sampling may be a useful tool for monitoring demographic patterns. However, we believe a larger sample size would be necessary for generating a statistically robust estimate of population density and abundance based on CMR models. [ABSTRACT FROM AUTHOR]

The Coastal Plain of the United States has not been recognized traditionally as a region experiencing significant soil erosion because of its low relief and permeable soils. Measurements of soil profile truncation in cemeteries were used to estimate rates of surface lowering and soil erosion in Sampson County, on the Coastal Plain of North Carolina. Measurements of the depth to the top of the argillic horizon (DTA) in relatively undisturbed profiles in small, perched cemeteries (ranging in age from 99–180 yr) were compared with adjacent cultivated fields. The mean truncation of soils from ten study sites was 25.8 cm, with the mean surface lowering of 2.0 cm. Correcting for compaction, this translates to a mean soil loss estimate of 24.4–27.4 Mg/ha/yr. [ABSTRACT FROM AUTHOR]

To assess the impact of habitat disturbance on birds in the Yuksom-Dzongri trekking corridor in western Sikkim, India, the relationships between bird community attributes-including migratory groups and feeding guilds—and vegetation variables were examined. Birds were observed in 19 100-m-long transects, 3 times per season per transect, for 2 seasons from 1997 to 1998 and 1998 to 1999, in an area where forests are subject to various degrees of pressure from human disturbances. Closed canopy forests with relatively Undisturbed habitat showed significant variation in habitat attributes, suggesting complexity of habitat structure. Bird species richness and diversity were significantly related to moderately disturbed habitats represented by Principal Component Analysis (PCA), where vegetation heterogeneity (vertical stratification and species corn position) was greater. Analysis by migratory groups did not show an interpretable relationship with the habitats, except for the seasonal movements of migratory groups when correlated with altitudinal gradient along the corridor. However, feeding guilds showed significant relationships when correlated with different habitat types. Guilds such as insectivores showed a significant positive relationship with relatively undisturbed habitat, whereas nectarivores and granivores were associated with disturbed habitat. Such relationships have the potential to help assess bird communities and their habitat preferences. Long-term monitoring at landscape level is necessary to understand the dynamics of habitat use patterns by bird communities in relation to spatial and temporal changes. [ABSTRACT FROM AUTHOR]

Livestock depredation by the endangered snow leopard (Panthera uncia) is an increasingly contentious issue in Himalayan villages, especially in or near protected areas. Mass attacks in which as many as 100 sheep and goats are killed in a single incident inevitably result in retaliation by local villagers. This article describes a community-based conservation initiative to address this problem in Hemis National Park, India. Human–wildlife conflict is alleviated by predator-proofing villagers’ nighttime livestock pens and by enhancing household incomes in environmentally sensitive and culturally compatible ways. The authors have found that the highly participatory strategy described here (Appreciative Participatory Planning and Action—APPA) leads to a sense of project ownership by local stakeholders, communal empowerment, self-reliance, and willingness to co-exist with snow leopards. The most significant conservation outcome of this process is the protection from retaliatory poaching of up to five snow leopards for every village’s livestock pens that are made predator-proof. [ABSTRACT FROM AUTHOR]

Most current clinical guidelines focus primarily on the management of individual cardiovascular risk factors, such as high blood pressure (BP), hypercholesterolemia, or diabetes. A more appropriate clinical approach to reducing cardiovascular disease risk would be based on a comprehensive evaluation of risk profile, and accurate stratification of global (absolute) risk in individual patients. We propose that global risk should be used as the main determinant of whom to treat, how to treat, and how much to treat.In this article we use a series of case studies to demonstrate the implications of replacing the traditional “single risk factor-based” approach to managing hypertension by one based on global risk assessment. In some situations patients with mildly elevated BP levels would not be recommended for antihypertensive drug treatment whereas others with lower BP would be treated, depending upon the entire risk profile.We propose to replace the single risk factor-based approach with the assessment of global cardiovascular risk, both in the clinical management of individual patients and in guidelines. [Copyright &y& Elsevier]

Cardiovascular disease prevention depends on reduction of risk factors, including hypertension. Guidelines designed to improve management of hypertension are widely available. Their purpose is to assemble the available data from basic biomedical science, epidemiology, and clinical science in an accessible form with which physicians and patients can make reasoned decisions for individual cases. However, guidelines have been neither widely accepted, nor effectively implemented. We recommend a strategy for guideline preparation designed to yield a product more user friendly, accessible, and effective. Guideline recommendations and the evidence used to make them should be based on an explicit grading system. Relevant clinical as well as nonclinical factors must be considered. Moreover, because the goal of antihypertensive therapy is to prevent cardiovascular events, and the likelihood of such events is determined by multifactor or absolute risk assessment, risk, rather than level of blood pressure (BP), should determine the need for therapy. Similarly, the benefit of therapy must be assessed by reduction in cardiovascular disease morbidity and mortality. [Copyright &y& Elsevier]

Objectives: To investigate (i) dietary patterns associated with consumption of vegetable oils rich in monounsaturated fatty acids (MUFA), and (ii) the risk of prostate cancer associated with consumption of these oils. Methods: A population-based case–control study was conducted in Auckland, New Zealand, involving 317 prostate cancer cases and 480 controls. A food-frequency questionnaire was used to collect data concerning consumption of MUFA-rich vegetable oils (including olive oil, canola or peanut oil) and other dietary variables. Biomarkers for fatty acids were measured in erythrocytes. Results: The group of participants who reported regular consumption of greater than 5.5 ml of MUFA-rich vegetable oils per day had a diet relatively high in monounsaturated fat, vegetables, lycopene, vitamin E, selenium, and n-3 fish oils. Increasing levels of MUFA-rich vegetable oil intake were associated with a progressive reduction in prostate cancer risk (multivariate relative risk = 0.5; 95% confidence interval 0.3–0.9; > 5.5 ml per day vs. non-consumption, p trend = 0.005), and similar trends were observed across all strata of socioeconomic status. Prostate cancer risk was not associated with intake of total MUFA or the major animal food sources of MUFA. Conclusion: This finding may be explained by the protective effect of an associated dietary pattern high in antioxidants and fish oils, an independent protective effect of MUFA-rich vegetable oils unrelated to the MUFA component, or a combination of these factors. [ABSTRACT FROM AUTHOR]

Presents a summary of the joint recommendations on prevention of coronary heart disease (CHD) in clinical practice in Great Britain. Lifestyle, risk factor and therapeutic targets for CHD preventions in patients with established CHD or other atherosclerotic disease and in healthy people at high risk of developing the disease; Coronary risk prediction charts for primary prevention.

Investigates the mortality rate from asthma, an epidemic in New Zealand. Trends in mortality of asthma in the international level during 1959-79; Examination of death related to respiratory condition in Auckland; Result and interpretation of data in asthma mortality rate from 1959-79.