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Your search keyword '"Kong, Renjiang"' showing total 2 results
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2 results on '"Kong, Renjiang"'

1. Carrier-free nanomedicine for enhanced photodynamic tumor therapy through glutathione S-transferase inhibition.

Author

Li, Xinyu, Kong, Renjiang, Li, Yanmei, Huang, Jiaqi, Zhou, Xiang, Li, Shiying, and Cheng, Hong

Subjects
PHOTODYNAMIC therapy, NANOMEDICINE, GLUTATHIONE transferase, GLUTATHIONE, OXIDATIVE stress, CHLORIDE channels
Abstract

Antioxidant-defense systems of tumor cells protect them from oxidative damage. Herein, a carrier-free nanomedicine is developed based on chlorine e6 (Ce6) and coniferyl ferulate (Con), which inhibits glutathione S-transferase (GST) activity to hamper antioxidant systems and amplify intracellular oxidative stress for enhanced photodynamic therapy. [ABSTRACT FROM AUTHOR]

Published
2022
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2. Self-delivery nanomedicine for chemotherapy sensitized photodynamic therapy.

Author

Liu, Lingshan, Zhou, Xiang, Zheng, Rongrong, Huang, Jiaqi, Kong, Renjiang, Li, Yanmei, Wang, Chang, Chen, Ali, Li, Shiying, and Cheng, Hong

Subjects
PHOTODYNAMIC therapy, CANCER chemotherapy, TUMOR microenvironment, CURCUMIN, NANOMEDICINE, CHLORINE
Abstract

A chlorine e6 (Ce6) and curcumin (Cur) based self-delivery nanomedicine (CeCu) is prepared for chemotherapy sensitized photodynamic therapy (PDT). The chemotherapeutic agent of Cur could inhibit the TrxR activity to destroy the cellular ROS-defence system for enhanced PDT, which provides synergistic effects for tumor precision therapy in consideration of the unfavorable tumor microenvironments. [ABSTRACT FROM AUTHOR]

Published
2021
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