Search

This study characterized a fragment of the cytochrome b gene from Ascochyta rabiei isolates collected in North Dakota, USA, that varied in sensitivity to quinone-outside inhibitor (QoI) fungicides. The sequenced genomic DNA fragment contained a group I intron immediately after codon 131. The size of the cytochrome b gene was estimated to be over 4·6 kb. Multiple alignment analysis of cDNA and protein sequences revealed a mutation that changed the codon for amino acid 143 from GGT to GCT, introducing an amino acid substitution from glycine to alanine (G143A), which is frequently associated with QoI resistance. Based on this mutation, a diagnostic PCR assay was developed using an approach called mismatch amplification mutation assay. This method was successfully validated by testing a total of 70 A. rabiei isolates, of which 38 isolates were found to be QoI-resistant. This fast and accurate PCR assay provides a very useful and simple screening method for QoI resistance in A. rabiei isolates. [ABSTRACT FROM AUTHOR]

In this paper we describe a simply connected component of the complex manifold Stab(X) of stability conditions on a generic complex torus X. A generic complex torus is a complex torus X with Hp,p(X) ∩ H2p(X, ℤ) = 0 for all 0 < p < dim X. [ABSTRACT FROM AUTHOR]

The rapid development of geriatric psychiatry in Israel reflects the major changes in the fields of demography, sociology and epidemiology. Faced with increased number of elderly patients with specific psychopathological problems, psychiatrists in Israel have become more interested in psychogeriatrics. In 1991 the Ministry of Health set up a special commission for the study of the needs of the elderly population in the field of geriatric psychiatry. Israel's psychogeriatricians, proceeding from the concept of comprehensive psychogeriatric medicine, made great efforts to attract other professional workers to collaborate with them.

The article discusses the growth of geriatric psychiatry round the world. The world's governments, health care, social and voluntary agencies are tackling the growth problem of mental illness in elderly people in diverse ways. Although developed industrial nations have been the first to face the urgent need to develop appropriate services, developing countries with a rapidly changing age structure are now facing a growing demand.