Background and gaps. The topic of indoor air quality (IAQ) in low-energy buildings has received increasing interest over the past few years. Often based on two measurement points and on passive measurements over one week, IAQ studies are struggling to allow the calculation of pollutants exposure. Objectives. We would like to improve the evaluation of the health impacts, through measurements able to estimate the exposure of the occupants. Methodology. This article presents detailed IAQ measurements taken in an energy-efficient occupied house in France. Two campaigns were conducted in winter and spring. Total volatile organic compounds (TVOC), formaldehyde, the particle numbers and PM2.5, carbon dioxide (CO2), relative humidity (RH), temperature (T), ventilation airflows, and weather conditions were dynamically measured in several points. Laboratory and low-cost devices were used, and an inter-comparison was carried out for them. A survey was conducted to record all the daily activities of the inhabitants. IAQ performance indicators based on the different pollutants were calculated. Results. PM2.5 cumulative exposure did not exceed the threshold available in the literature. Formaldehyde concentrations were high, in the kitchen, where the average concentrations exceeded the threshold. However, the formaldehyde cumulative exposure of the occupants did not exceed the threshold. TVOC concentrations were found to reach the threshold. With these measurements performed with high spatial and temporal discretization, we showed that such detailed data allow for a better-quality health impacts assessment and for a better understanding of the transport of pollutants between rooms. [ABSTRACT FROM AUTHOR]