14 results on '"Oyemolade, Toyin A."'
Search Results
2. Intracranial lipoma associated with a subcutaneous lipoma. A rare entity.
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Oyemolade, Toyin Ayofe and Balogun, James Ayokunle
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INTRACRANIAL tumors ,LIPOMA ,AGENESIS of corpus callosum ,AUTOPSY ,HUMAN abnormalities - Abstract
Intracranial lipomas are rare, frequently asymptomatic, congenital malformations. They are most commonly located in the pericallosal region and are often detected incidentally during neuroimaging studies or postmortem examinations. While other associated brain malformations, most notably callosal agenesis, are frequently reported, association with a subcutaneous scalp lipoma is extremely rare. We present a case of pericallosal lipoma associated with callosal agenesis and subcutaneous lipoma over the anterior fontanelle in a 6-month-old female infant who had excision of only the extracranial mass and has remained asymptomatic from the intracranial mass for the 3 years of follow up. [ABSTRACT FROM AUTHOR]
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- 2023
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3. Paediatric Spinal Tumours: Profile and Treatment Outcome in a Nigerian Tertiary Institution.
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Badejo, Oluwakemi Aderonke, Oyemolade, Toyin Ayofe, Adeolu, Augustine Abiodun, and Shokunbi, Matthew Temitayo
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CENTRAL nervous system tumors ,CHILD patients ,TREATMENT effectiveness ,CENTRAL nervous system ,TUMORS ,PEDIATRICS - Abstract
Introduction: Paediatric spinal tumours are rare, accounting for 1–10% of all childhood central nervous system tumours. There is a paucity of information on spinal tumours in Sub-Saharan Africa. This is particularly so in the Nigerian paediatric population where neuro-oncologic data are limited. Indeed, there is no previously published work on paediatric spinal tumours in the Nigerian neurosurgical literature. The authors aim to document the profile of paediatric spinal tumours in a Nigerian tertiary institution and to contribute to the available data on paediatric central nervous system tumours in West Africa. Methods: We retrospectively evaluated data on paediatric patients who underwent surgery for spine tumours over a 20-year period at our institution. Results: A total of 12 patients were managed for paediatric spine tumours during the study period. These had a male:female ratio of 1:1.4, and their ages ranged between 3 and 18 years (mean: 12.83 ± 4.75 years). The highest incidence (6/12) was seen in the 15–18 years age group. The mean duration of symptoms was 10.2 months. More than half (7/12) of the patients presented with symptoms with duration of at least 6 months. Motor deficit was present in all patients at presentation. Two-thirds of the tumours were in the thoracic region, 1 was located in the cervical region, while the remaining 3 tumours were cervicothoracic. The tumour was extradural in location in 8 of our patients and intramedullary in the remaining 4. Astrocytoma, intramedullary in all cases, was the most predominant histological tumour type (3/12) in our series. Postoperative neurological improvement occurred in 7 of the patients while 5 remained the same. There was no permanent postoperative neurological deterioration or perioperative mortality. Conclusion: Paediatric spinal tumours mostly affected older children in our study group and were predominantly astrocytic in nature. The most common tumour location was extradural, involving mostly the thoracic spinal level. The preoperative neurological status correlates with the postoperative functional outcome. Therefore, the need for early diagnosis and treatment of these tumours cannot be overemphasized. [ABSTRACT FROM AUTHOR]
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- 2022
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4. Knowledge of the Glasgow Coma Scale among Physician Interns in a Nigerian Tertiary Health Facility.
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Oyemolade, Toyin Ayofe, Akinkunmi, Mojirade A., Ogunyileka, Oluwakemi Comfort, Arogundade, Folawemimo M., Ehinola, Busayo A., and Adeleye, Amos O.
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- 2022
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5. Burden of pediatric neurosurgical disease in a rural developing country: perspectives from southwest Nigeria.
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Oyemolade, Toyin A., Adeleye, Amos O., Olusola, Ayodele J., Ehinola, Busayo A., Aikhomu, Ebosetale P., and Iroko, Anita A.
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- 2022
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6. Mannitol Dosing Error during Pre-neurosurgical Care of Head Injury: A Neurosurgical In-Hospital Survey from Ibadan, Nigeria.
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Adeleye, Amos Olufemi, Oyemolade, Toyin Ayofe, Malomo, Toluyemi Adefolarin, and Okere, Oghenekevwe Efe
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MANNITOL ,HEAD injuries ,CAREGIVERS ,HEALTH facilities ,MEDICAL errors ,NEUROSURGEONS ,BOLUS radiotherapy - Abstract
Objectives Inappropriate use of mannitol is a medical error seen frequently in pre-neurosurgical head injury (HI) care that may result in serious adverse effects. This study explored this medical error amongst HI patients in a Nigerian neurosurgery unit. Methods We performed a cross-sectional analysis of a prospective cohort of HI patients who were administered mannitol by their initial non-neurosurgical health care givers before referral to our center over a 22-month period. Statistical Analysis A statistical software was used for the analysis with which an α value of <0.05 was deemed clinically significant. Results Seventy-one patients were recruited: 17 (23.9%) from private hospitals, 13 (18.3%) from primary health facilities (PHFs), 20 (28.2%) from secondary health facilities (SHFs), and 21 (29.6%) from tertiary health facilities (THFs). Thirteen patients (18.3%) had mild HI; 29 (40.8%) each had moderate and severe HI, respectively. Pupillary abnormalities were documented in five patients (7.04%) with severe HI and neurological deterioration in two with mild HI. Mannitol administration was deemed appropriate in only 43.7% (31/71). Data on mannitol dosing in 60.6% (43/71) of the patients showed 8/43 (18.6%) receiving continuous 10% mannitol infusion. The remaining 35/43 received mannitol as a 20% solution but also showing dosing error in 62.9% (22/35): overdosing in 7/35 (20%), and nonbolus administration in 15/35 (42.9%). The distribution of the dosing error among the referring health facilities (all the 13 [100%] patients from private hospitals, 66.7% from PHF, 60% from SHF, and 45.5% from THF) showed a trend of better performance (p = 0.002) by the THFs. Conclusion Mannitol use is apparently fraught with an understudied medical error in the pre-neurosurgical care of the head injured. [ABSTRACT FROM AUTHOR]
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- 2021
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7. Bedside single burr hole craniostomy drainage of chronic subdural hematoma in the emergency room: A useful option in resource challenged settings.
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Oyemolade, Toyin Ayofe and Adeolu, Augustine Abiodun
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SUBDURAL hematoma ,NEUROLOGICAL disorders ,HOSPITAL emergency services ,GLASGOW Coma Scale ,LOCAL anesthetics ,LOCAL anesthesia - Abstract
Background: In resource challenged environments, the standard treatment of chronic subdural hematoma (CSDH) in the theater may be delayed because of the endemic financial constraint and logistic problems with consequent negative impact on the outcome. An emergency bedside burr hole craniostomy with a local anesthetic at the accident and emergency ward may be lifesaving in patients presenting in extreme neurological conditions in these settings. Case Description: We presented three patients (one male and two females) with CSDH who presented at our service in poor neurological condition. The patients were between 49 and 70 years. The Glasgow Coma Score ranged from 3 to 6. The three patients had respiratory and pupillary abnormalities at presentation. They all had bedside single frontal burr hole craniostomy drainage of the hematoma under local anesthesia at the accident and emergency unit of the hospital. Surgery was done within 1 h of review by the neurosurgical team in all cases. The duration of hospital stay ranged from 8 to 24 days. The outcome was good in all cases. Conclusion: Bedside single burr hole craniostomy at the accident and emergency unit may be lifesaving in patients with CSDH who present in extreme neurological condition but in whom prompt standard surgical treatment in the theater is not feasible. [ABSTRACT FROM AUTHOR]
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- 2020
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8. Determinants of discharge against medical advice from a rural neurosurgical service in a developing country: A prospective observational study.
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Oyemolade, Toyin Ayofe, Adeleye, Amos Olufemi, Ogunyileka, Oluwakemi C., Arogundade, Folawemimo M., Olusola, Ayodele J., and Aribisala, Oluwadamilola O.
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DEVELOPING countries ,LONGITUDINAL method ,FALLOW deer ,HEALTH literacy ,SCIENTIFIC observation - Abstract
Background: In low-resource regions of the world, discharge against medical advice (DAMA) is one empiric contributory factor to poor in-hospital outcome that is not often mentioned. This study aims to investigate the determinants of DAMA from a rural neurosurgical service in a developing country. Methods: This was a prospective observational study of all patients who discharged against medical advice in our service between November 2018 and October 2019. Results: There were 88 patients, 67 (76.1%) males, in the study, (M:F = 3.2:1), representing 17.4% of our patient population in the study period. The peak incidence was in the 20-29 years age group which accounted for 37.5% of the cases. About 55% of the patients presented directly to our center; 31.8% were referred from other hospitals, while 3.4% came from traditional caregivers and 1.1% from religious homes. Head injury was the most common indication for presentation (76.1% of the cases). The duration of hospital stay ranged from 2 h to 14 days. Majority of the patients (87.5%) left the hospital within 8 h of presentation. The reason for DAMA was financial constraints in 50% of cases, inadequate health literacy in 20.5%, financial constraints and poor health literacy together in 12.5%, religious misgivings in 4.5%, and traditional belief in 2.3%. Neurotrauma was predictive of early DAMA (P = 0.001). Conclusion: The rate of DAMA was high in our study. Financial constraints with other socioeconomic limitations were the most common causes of DAMA in our environment. [ABSTRACT FROM AUTHOR]
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- 2020
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9. Intracranial infection in patients with myelomeningocele: profile and risk factors.
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Anegbe, Ambrose O., Shokunbi, M. Temitayo, Oyemolade, Toyin A, and Badejo, Oluwakemi A.
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MYELOMENINGOCELE ,DISEASE risk factors ,SPINA bifida ,LUMBOSACRAL region ,LOGISTIC regression analysis ,PITUITARY surgery ,CEREBROSPINAL fluid shunts ,CEREBROSPINAL fluid - Abstract
Purpose: To describe the profile and determine the risk factors for the development of intracranial infections (ICI) in paediatric patients with myelomeningocele (MMC). Methods: Retrospective analysis of data from the records of patients with MMC admitted into our hospital between January 2006 and December 2015. Results: We managed a total of 688 paediatric non-trauma neurosurgical patients in our facility during the study period. 29.4% of these patients had MMC. We found the records for 49% of the patients. The male: female ratio was 1.3:1. Most of the MMCs were located in the lumbosacral region (71.7%). The lesion was ruptured in 42.4%, unruptured in 53.5%, and indeterminate in 4.0% of the patients. 48.5% of the MMCs were infected at presentation. Surgical repair of the spinal dysraphism was performed in 74.7% of the patients. Postoperative complications observed in our series include wound dehiscence, cerebrospinal fluid leak, and pseudomeningocele which occurred in 13.5%, 12.2%, and 2.7% of the operated cases of MMC respectively. 28.3% of the patients with MMC developed ICI during the course of hospitalization. 71.4% of patients with MMC-associated ICI had septic neural placode at the initial clinical evaluation. 70% of the patients who had wound dehiscence post-operatively developed ICI. Loculations and abscesses occurred only in patients who had surgical repair. A multivariate logistic regression analysis revealed that septic neural placode, hydrocephalus, a supra-lumbar location of the MMCs and surgical intervention were predictive of ICI (p < 0.05). Conclusion: Infection of the neural placode, hydrocephalus, locations of the lesions above the lumbar region, and surgical repair were the statistically significant risk factors for ICI in our study population. The trending but statistically insignificant risk factors for ICI in our series may require further assessment with a larger sample size. [ABSTRACT FROM AUTHOR]
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- 2019
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10. Indiscriminate Use of Antibiotics in Neurotrauma Patients Referred for Expert Neurosurgical Care in a Developing Country.
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Oyemolade, Toyin A., Malomo, Toluyemi A., and Adeleye, Amos O.
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HEALTH facilities ,NEUROSURGEONS ,DEVELOPING countries ,NERVOUS system injuries ,ANTIBIOTICS ,ASPIRATION pneumonia - Abstract
Background In Nigeria, pre-neurosurgical care of most neurotrauma patients usually involves administration of many empirical agents including antibiotics with no apparent indications. This practice is fraught with two particular dangers: increase in health care costs and development of drug resistance. This study aimed to interrogate antibiotic stewardship in the pre-neurosurgical care of neurotrauma patients referred to our practice. Materials and Methods This 7-month prospective descriptive study was performed in one University Teaching Hospital of a developing country. Clinical data on all admitted neurotrauma patients with information on the pre-neurosurgical treatment received were captured and analyzed. Results There were 113 patients, 87(77.0%) males; 103(91.2%) had head injury, and 10(8.8%) spinal cord injury. Associated systemic injuries occurred in 47(41.6%): 40 involved skeletal and soft tissue systems, and 12(10.6%) presented with aspiration pneumonitis. These patients were referrals from public health facilities including primary health facilities (PHF), secondary (SHF), and tertiary (THF), as well as private clinics (PC). Antibiotics were given to 74 (65.5%) patients, with a probabilistic indication in only 17.6% (13/74) of these. The proportional distribution of this antibiotic administration according to the referral base was not statistically significant (χ
2 =6.87, p = 0.3): 70% (14/20) from PHF, 56% (14/25) from SHF, 71% (23/32) from THF, and 63% (23/36) from PC. The antimicrobial agent administered was specified in 40 cases: Ceftriaxone was the commonest antibiotic agent implicated. Conclusion There is apparent unnecessary exposure of patients to antibiotics in the pre-neurosurgical care of neurotrauma in this study. There is, therefore, need for education on antibiotic stewardship to the group of health workers involved. [ABSTRACT FROM AUTHOR]- Published
- 2019
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11. Determinants of timing of presentation of neurotrauma patients to a neurosurgical center in a developing country.
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Malomo, Toluyemi, Oyemolade, Toyin, and Adeleye, Amos
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NERVOUS system injuries ,NEUROSURGERY ,NEURONS ,HEAD injuries ,SPINAL cord injuries ,WOUNDS & injuries - Abstract
Background: A major goal in neurotrauma management is the prevention of secondary neuronal injuries. This goal is time bound as neurological deficits once established are usually irreversible. Late presentation is the norm in most neurotrauma patients in developing countries. Aims: The aim of the study was to review the timing of presentation of neurotrauma patients and the possible causes of their late presentation for neurosurgical care in our practice. Methods: A cross-sectional study of a 4-month prospective database of neurotrauma patients presenting to the University College Hospital, Ibadan, was done. The participants' biodata, injury characteristics, initial-care details before referral, and information on timing and causes of delay were analyzed. Results: The study subjects included 111 patients, 80.2% (89/111) were males, and 52.8% aged 21–40 years. Head injury (HI), spinal cord injury (SCI), and combined HI and SCI occurred, respectively, in 80.2%, 14.4%, and 5.4%. Road accidents followed by falls were seen in 73.9% and 14.4% (16), respectively. Just 46.8% (52/111) cases presented within 12 h of injury and only 37 (33.3%) within 4 h. Majority, 83.8% (93/111) were referrals from primary care. These referrals were delayed in 81.7% (76/93) of these. The referring health facilities were located intracity with our center in 54%. Other causes of delayed presentation of these study participants included long-distance travel to our center, lack of funds, or a combination of the above factors. Eighty-nine patients (80.2%) were brought in by family members and the remaining minority by passers-by and road safety personnel. Conclusions: Delayed referral from primary care features prominently in timing of presentation of neurotrauma patients in Nigeria. There is a need for collaboration as well as continuing medical education between the neurotrauma specialists and primary care physicians. [ABSTRACT FROM AUTHOR]
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- 2018
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12. Response.
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Oyemolade, Toyin A. and Adeleye, Amos O.
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- 2022
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13. Extensive vertebral scalloping in a thoracolumbar junction spinal schwannoma.
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Oyemolade, Toyin Ayofe and Adeolu, Augustine Abiodun
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SCALLOPS ,MAGNETIC resonance imaging ,SCHWANNOMAS ,COMPUTED tomography - Abstract
Severe vertebral scalloping in spinal schwannoma is very rare. When present, extensive scalloping of the vertebral bodies possesses significant treatment challenges in patients with spinal tumors. We present the computed tomography scan and magnetic resonance images of spinal schwannoma with marked vertebral scalloping in a 40-year-old Nigerian. [ABSTRACT FROM AUTHOR]
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- 2020
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14. Spinal extradural arachnoid cyst in a child—a case report.
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Oyemolade, Toyin A, Adeolu, Augustine A, and Idowu, Olusola K
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ARACHNOID cysts ,SPINAL nerve roots ,SPINAL cord compression ,SUBARACHNOID space ,DURA mater - Abstract
Extradural spinal arachnoid cysts are rare lesions. They frequently communicate with the subarachnoid space through a defect in the dura. Symptoms result from compression of the spinal cord or nerve roots. The treatment of choice is complete surgical excision. We report the case of a 12-year-old girl with extradural spinal arachnoid cyst who had complete surgical excision with good outcome. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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