Search

In this study, some life history characteristics (27 adult and 7 subadult specimens) of a highland population (Sütçüler) of the Lacerta pamphylica species in Isparta province of Türkiye were investigated by applying the skeletochronology method. The mean age and SVL values were 5.67 ± 0.50 years and 106.28 ± 2.25 mm in adult males and 5.33 ± 0.46 years and 102.65 ± 2.65 mm in adult females in the population. The age range varies between 3–10 years in males and 3–8 years in females. The age of subadult males and subadult females was 2 years. The presented study provides information on the age of the species Lacerta pamphylica for the first time. [ABSTRACT FROM AUTHOR]

Simple Summary: The main objective of this study was to provide the first information on the age structure of the critically endangered and endemic frog species, Rana tavasensis, in Türkiye. Age data are important in evaluating the dynamics of populations and effective conservation strategies should be addressed according to age-related parameters (e.g., longevity, mean age, growth rate, and age at maturity). Skeletochronology is an effective method for estimating the ages of amphibians, and using this method, we determined the mean age, longevity, and relationship between age and body size in both males and females of a R. tavasensis population in Çakıroluk, the terra-typica, located in Denizli province, Türkiye. The results of our study provides insights for taking feature measures to protect these frogs, whose number has progressively declined each year due to habitat loss and degradation. This study used skeletochronology to assess the relationships between age and body length among individuals in a population of the Tavas Frog (Rana tavasensis), located in the Çakıroluk plateau, Tavas district, Denizli province. The age varied from 3 to 12 years in both adult males and females. The age was 2 years in two subadult males, while it was 1 year in one juvenile specimen. The mean SVL and age of the adult individuals of the Çakıroluk population were 62.75 mm and 6.70 years in male specimens and 58.04 mm and 6.12 years in female specimens. A positive correlation was found between body size (SVL) and age in adult female and male individuals of the species. Because the number of individuals of the species is rapidly decreasing, species protection measures, based on knowledge related to the age structure and breeding features of these frogs, must be put into action urgently. [ABSTRACT FROM AUTHOR]

Age and body size in a lowland population of Lissotriton schmidtleri in the İstanbul Province of Türkiye were examined by applying the skeletochronology method. The age range varies between 5 to 11 years in males and 4 to 8 years in females. The mean age and SVL values were 8.1 years and 36.28 mm in males and 6.4 years and 37.72 mm in females. The mean SVL and age values showed a significant difference between the sexes. The present study showed sexual dimorphism and different life expectancy between sexes. The estimated potential reproductive lifespan was higher in males than females. [ABSTRACT FROM AUTHOR]

Background: The aim of this study was to compare the cyclic fatigue resistance (CFR) of the newly developed pediatric nickel-titanium (NiTi) rotary file systems for root canal preparation of primary teeth. Methods: Eighty pediatric NiTi rotary file systems files were used in this study, including 20 EasyInSmile X-Baby (25/0.04), 20 Scope miniScope (25/0.04), 20 EndoArt Pedo Gold (25/0.04), and 20 EndoArt Pedo Blue (25/0.04) files. Static CFR tests; performed on a custom-made stainless steel block with an inner diameter of 1.5 mm, an angle of curvature of 60° and a curved artificial canal with a radius of curvature of 5 mm. The test system was filled with distilled water and the temperature was kept constant at 35 ± 1 °C. The files were rotated in the simulated canal until fracture occurred. The number of cycles to failure (NCF) data was recorded, and all the fracture surfaces of the files were evaluated using scanning electron microscopy (SEM). One-way ANOVA and Tukey tests were used for statistical analysis of the data, and the significance level was set at p < 0.05. Results: EndoArt Pedo Blue showed the highest NCF values (2668.10 ± 755.26), while the miniScope showed the lowest NCF values (453.65 ± 72.51), with a statistically significant difference between all the tested file systems (p < 0.05). There was no statistical difference in terms of fractured fragment lengths among all tested files (p > 0.05). Conclusion: The EndoArt Pedo Blue file system showed the best CFR performance among the four file systems specifically designed for primary teeth. [ABSTRACT FROM AUTHOR]

Background: Adverse non-motor outcomes are common after acute stroke and likely to substantially affect quality of life, yet few studies have comprehensively assessed their prevalence, patterns, and predictors across multiple health domains. Aims: We aimed to identify the prevalence, patterns, and the factors associated with non-motor outcomes 30 days after stroke. Methods: This prospective observational hospital cohort study—Stroke Investigation in North and Central London (SIGNAL)—identified patients with acute ischemic stroke or intracerebral hemorrhage (ICH) admitted to the Hyperacute Stroke Unit (HASU) at University College Hospital (UCH), London, between August 1, 2018 and August 31, 2019. We assessed non-motor outcomes (anxiety, depression, fatigue, sleep, participation in social roles and activities, pain, bowel function, and bladder function) at 30-day follow-up using the Patient-Reported Outcome Measurement Information System-Version 29 (PROMIS-29) scale and Barthel Index scale. Results: We obtained follow-up data for 605/719 (84.1%) eligible patients (mean age 72.0 years; 48.3% female; 521 with ischemic stroke, 84 with ICH). Anxiety (57.0%), fatigue (52.7%), bladder dysfunction (50.2%), reduced social participation (49.2%), and pain (47.9%) were the commonest adverse non-motor outcomes. The rates of adverse non-motor outcomes in ⩾ 1, ⩾ 2 and ⩾ 3 domains were 89%, 66.3%, and 45.8%, respectively; in adjusted analyses, stroke due to ICH (compared to ischemic stroke) and admission stroke severity were the strongest and most consistent predictors. There were significant correlations between bowel dysfunction and bladder dysfunction (κ = 0.908); reduced social participation and bladder dysfunction (κ = 0.844); and anxiety and fatigue (κ = 0.613). We did not identify correlations for other pairs of non-motor domains. Conclusion: Adverse non-motor outcomes were very common at 30 days after stroke, affecting nearly 90% of evaluated patients in at least one health domain, about two-thirds in two or more domains, and almost 50% in three or more domains. Stroke due to ICH and admission stroke severity were the strongest and most consistent predictors. Adverse outcomes occurred in pairs of domains, such as with anxiety and fatigue. Our findings emphasize the importance of a multi-domain approach to effectively identify adverse non-motor outcomes after stroke to inform the development of more holistic patient care pathways after stroke. [ABSTRACT FROM AUTHOR]

Background: Intracranial arterial dolichoectasia (IADE) is a common arterial finding of dilation, elongation, or both, affecting large intracranial vessels, and associated with vascular risk factors, including hypertension. Associations of IADE with neuroimaging cerebral small vessel disease (CSVD) may be relevant for diagnosis and prognosis in patients with stroke. The study aimed to conduct an updated systematic review and meta-analysis of observational studies to investigate the relationships of IADE with well-defined CSVD markers in patients with ischaemic stroke. Methods: We systematically searched PubMed, Embase, and Scopus for studies on IADE in ischaemic stroke patients with fulfilling predefined inclusion criteria. We pooled data to conduct a meta-analysis to compare the prevalence of SVD markers between patients with and without IADE groups using risk ratios (RRs) and 95% confidence intervals (CIs). Results: From 157 retrieved abstracts, we included six studies from seven publications comprising 6102 patients with ischaemic stroke. The mean age of patients was 52.8 years, and 3691 (60.5%) were male. IADE was diagnosed in 11.4% (95% CI 8.9–13.9) (761) of included patients; 51.8% (3160) had hypertension. Compared to patients without IADE, individuals diagnosed with IADE had a significantly increased prevalence of lacune (RR 1.67, 95% CI 1.36–2.06, P < 0.01, I2 = 0.00%), cerebral microbleeds (CMBs) (RR 2.56, 95% CI 1.53–4.28, P < 0.01, I2 = 84.95%) and white matter hyperintensities (WMHs) (RR 2.17, 95% CI 1.84–2.56, P < 0.01, I2 = 0.00%). Conclusions: In patients with ischaemic stroke, IADE is associated with a higher prevalence of CSVD markers, including lacunes, CMBs, and WMHs. Further studies are needed to clarify the mechanisms underlying these associations and their potential relevance for the understanding, diagnosis, and treatment of CSVD. [ABSTRACT FROM AUTHOR]

In order to observe the habitats of the Anatolian banded newt (Ommatotriton nesterovi), field studies were carried out in a total of 11 different localities in Samsun, Zonguldak, Bartın, and Karabük provinces, and 12 ones in Trabzon and Rize provinces for the Caucasian banded newt (Ommatotriton ophryticus). MaxEnt modeling was performed in order to test the compatibility of the information obtained in field studies with the results obtained as a result of modeling. The coordinate data from of a total of 95 separate localities belonging to the O. nesterovi that exist in the literature and were obtained in this study, and 43 ones belonging to the O. ophryticus were used. When the data obtained from field observations and modeling in this study are evaluated together, it is understood that the Anatolian banded newt endemic to Türkiye chooses places with lower altitude and areas with lower slopes and forest that do not receive much direct sunlight takes an important place in the habitat preference of this species compared to the Caucasian banded newt distributed in Türkiye, Georgia, Russia, and Armenia. [ABSTRACT FROM AUTHOR]

Background: Pulmonary embolism (PE) is a common complication of deep vein thrombosis that causes high mortality and morbidity. This study aimed to determine the relationship between clinical risk scoring for early mortality and fractional exhaled nitric oxide (FeNO) in PE patients. Methods: The study included a total of 98 subjects, 68 patients diagnosed with PE in the emergency department, and 30 healthy controls. Patients with PE were grouped according to clinical scoring of early mortality risk as low (n = 20), moderate-low (n = 24), and moderate-high (n = 24) risk. FeNO levels were measured after diagnosis. Results: FeNO levels were significantly higher in patients with moderate-high risk PE compared to the other three groups and in those with moderate-low risk PE compared to the control group (p < 0.001 for all). Moderate to strong positive correlations were observed between FeNO level and mean pulmonary artery pressure (r = 0.818, p = 0.01), troponin-I (r = 0.67, p = 0.01), pro-BNP (r = 0.762, p = 0.01), and D-dimer levels (r = 0.652, p = 0.01). A FeNO cutoff value of 7.5 ppb had 84% sensitivity and 78% specificity in differentiating moderate-high risk PE from moderate-low risk PE. Conclusions: FeNO may be as reliable, noninvasive, and easily accessible as cardiac biomarkers in clinical risk scoring for early mortality in PE patients. [ABSTRACT FROM AUTHOR]

Copyright of Necmettin Erbakan University Dental Journal (NEU Dent J) is the property of Necmettin Erbakan University Dental Journal (NEU Dent J) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Textiles & Engineers / Tekstil ve Mühendis is the property of Union of Chambers of Turkish Engineers & Architects, Chamber of Textile Engineers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Pulmonary embolism (PE) is an emergent pulmonary vascular pathology with high morbidity and mortality. This study investigated the relationship between serum lipocalin-2 and -10 levels and clinical score for early mortality risk in patients diagnosed with PE in the emergency department. Methods: The study included 100 patients with PE and 25 healthy controls. The patients with PE were classified as high-risk (Group 1; n = 25), high-intermediate-risk (Group 2; n = 25), low-intermediate-risk (Group 3; n = 25), and low-risk patients (Group 4; n = 25). Serum lipocalin 2 and 10 levels at admission were measured by enzyme-linked immunosorbent assay and compared between the five groups. Results: Serum lipocalin-2 concentration was significantly higher in Group 1 when compared with the other groups (p = 0.003, =0.001, <0.001, and <0.001, respectively). Serum lipocalin-10 level was also higher in Group 1 than in the other groups (p < 0.001 for all). In addition, lipocalin-10 level was higher in Group 2 than in Group 3, Group 4, and the control group (p = 0.05, <0.001, and <0.001, respectively). In the receiver operating characteristic (ROC) analysis of the utility of lipocalin-2 and lipocalin-10 in the differentiation of high-risk PE patients, for lipocalin-2, a cut-off value of 677.7 ng/L had 90% sensitivity and 79% specificity, while for lipocalin-10, a cut-off value of 506.4 ng/L had 90% sensitivity and 87% specificity. Conclusion: Clinical risk scoring for early mortality in PE is important for treatment planning. Serum lipocalin-2 and -10 levels may be useful in early diagnosis and treatment planning in PE. [ABSTRACT FROM AUTHOR]

Purpose: This study aimed to investigate the effect of surface treatment and type of composite resin material on the color stability and surface roughness of different denture characterizing composites. Materials and methods: Two nanohybrids [Gradia Plus Gum, (GP) and SR Nexco Paste Gingiva, (SR)] and one microhybrid gingiva‐colored composite resin [Amaris Gingiva, (AG)] were investigated. A total of 120 disk‐shaped samples were prepared, 40 of each material. Samples were divided into two groups (n = 20) for each material according to the surface treatment applied: conventional polishing (control) and coated with a sealant in addition to the surface polishing. All groups were thermocycled. The surface roughness (Ra) was measured using a profilometer after thermal cycling. The samples were then divided into 2 subgroups (n = 10) and stored for 7 days in distilled water or coffee solution. Color differences (ΔE00) were calculated with a spectrophotometer. Results were evaluated with Kruskal‐Wallis and Mann‐Whitney U statistical analysis. Results: The type of denture characterizing composite material and surface treatment method revealed statistically significant differences for the ΔE00 (after immersion both in coffee and distilled water) and the Ra values of denture characterizing composite (p < 0.001 for both). All sealed groups showed significantly higher Ra than the all polished groups. Both in the polished groups and the sealant applied groups, the GP had the highest mean Ra values (0.29 ±0.05 μm and 0.47 ±0.09 μm, respectively). It was followed by SR (0.23 ±0.06 μm and 0.41 ±0.10 μm, respectively), and AG groups (0.20 ±0.06 μm and 0.39 ±0.09 μm, respectively). According to the mean ΔE00 results, all composite groups showed significantly higher ΔE00 values immersed in coffee solutions compared to distilled water. In coffee solutions, the highest ΔE00 was observed in the polished GP (1.90 ±0.40), and the lowest ΔE00 was observed in the polished SR (0.97 ±0.36). The sealed groups showed higher ΔE00 than the polished groups, except for GP. Conclusions: The surface roughness value of sealant applied groups were significantly higher than those of the polished groups. The surface sealant application significantly increased the staining of all composite groups compared to conventional polishing, except for GP. [ABSTRACT FROM AUTHOR]

The present study provides the first records (Birlik neighbourhood and Devrek District in Zonguldak Province) of the Bulgarian bent-toed gecko Mediodactylus danilewskii from the western Black Sea coastal region of Turkey. Morphological data of specimens from Edirne (Vakıf Village of Enez District) located in the Thrace part of Turkey are compared to those of specimens from the coast of the western Black Sea. The pholidolial and morphometric characters and colour-pattern features of the Zonguldak and Edirne specimens were found to be similar to those of M. danilewskii reported in the literature. [ABSTRACT FROM AUTHOR]

Background: Cerebral amyloid angiopathy (CAA), a common cause of intracerebral hemorrhage (ICH), is diagnosed using the Boston criteria including magnetic resonance imaging (MRI) biomarkers (cerebral microbleeds (CMBs) and cortical superficial siderosis (cSS). The simplified Edinburgh criteria include computed tomography (CT) biomarkers (subarachnoid extension (SAE) and finger-like projections (FLPs)). The underlying mechanisms and diagnostic accuracy of CT compared to MRI biomarkers of CAA are unknown. Methods: We included 140 survivors of spontaneous lobar supratentorial ICH with both acute CT and MRI. We assessed associations between MRI and CT biomarkers and the diagnostic accuracy of CT- compared to MRI-based criteria. Results: FLPs were more common in patients with strictly lobar CMB (44.7% vs 23.5%; p = 0.014) and SAE was more common in patients with cSS (61.3% vs 31.2%; p = 0.002). The high probability of the CAA category of the simplified Edinburgh criteria showed 87.2% (95% confidence interval (CI): 78.3–93.4) specificity, 29.6% (95% CI: 18.0–43.6) sensitivity, 59.3% (95% CI: 38.8–77.6) positive predictive value, and 66.4% (95%: CI 56.9–75.0) negative predictive value, 2.3 (95% CI: 1.2–4.6) positive likelihood ratio and 0.8 (95% CI 0.7–1.0) negative likelihood ratio for probable CAA (vs non-probable CAA), defined by the modified Boston criteria; the area under the receiver operating characteristic curve (AUROC) was 0.62 (95% CI: 0.54–0.71). Conclusion: In lobar ICH survivors, we found associations between putative biomarkers of parenchymal CAA (FLP and strictly lobar CMBs) and putative biomarkers of leptomeningeal CAA (SAE and cSS). In a hospital population, CT biomarkers might help rule-in probable CAA (diagnosed using the Boston criteria), but their absence is probably not as useful to rule it out, suggesting an important continued role for MRI in ICH survivors with suspected CAA. [ABSTRACT FROM AUTHOR]

Copyright of Acta Odontologica Turcica is the property of Acta Odontologica Turcica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Some life-history traits (e.g. body size, SSD and age) of the Danford's lizard Anatololacerta danfordi were studied applying skeletochronology techniques to the phalangeal bones (n = 33). The mean of the snout-vent-length (SVL) was 59.02 ± 1.07 mm in females and 62.17 ± 1.38 mm in males. The mean SVL was not significantly different between sexes. Sexual size dimorphism was weakly expressed in the slightly bigger SVL of the males (SDI = -0.053). Sexual maturity was attained between the second and the fourth year of life in both sexes. The age ranged from 2 to 6 years in females and from 3 to 8 years in males. The means of age were 4.29 ± 0.31 LAGs in female specimens and 4.63 ± 0.37 LAGs in male specimens. The mean age was not significantly different between the sexes. [ABSTRACT FROM AUTHOR]

Background and purpose: The COVID-19 pandemic and related social isolation measures are likely to have adverse consequences on community healthcare provision and outcome after acute illnesses treated in hospital, including stroke. We aimed to evaluate the impact of the COVID-19 pandemic on patient-reported health outcomes after hospital admission for acute stroke. Methods: This retrospective study included adults with acute stroke admitted to the University College Hospital NHS Foundation Trust Hyperacute Stroke Unit. We included two separate cohorts of consecutively enrolled patients from the same geographical population at two time points: 16th March–16th May 2018 (pre-COVID-19 pandemic); and 16th March–16th May 2020 (during the COVID-19 pandemic). Patients in both cohorts completed the validated Patient Reported Outcomes Measurement Information System–29 (PROMIS-29 version 2.0) at 30 days after stroke. Results: We included 205 patients who were alive at 30 days (106 admitted before and 99 admitted during the COVID-19 pandemic), of whom 201/205 (98%) provided patient-reported health outcomes. After adjustment for confounding factors, admission with acute stroke during the COVID-19 pandemic was independently associated with increased anxiety (β = 28.0, p < 0.001), fatigue (β = 9.3, p < 0.001), depression (β = 4.5, p = 0.002), sleep disturbance (β = 2.3, p = 0.018), pain interference (β = 10.8, p < 0.001); and reduced physical function (β = 5.2, p < 0.001) and participation in social roles and activities (β = 6.9, p < 0.001). Conclusion: Compared with the pre-pandemic cohort, patients admitted with acute stroke during the first wave of the COVID-19 pandemic reported poorer health outcomes at 30 day follow-up in all domains. Stroke service planning for any future pandemic should include measures to mitigate this major adverse impact on patient health. [ABSTRACT FROM AUTHOR]

Life-history traits (e.g. body size, sexual size dimorphism and age) of a Turkish population of the Lebanon lizard Phoenicolacerta laevis were studied using skeletochronology techniques. We measured phalangeal bones (n = 30). The mean snout-vent length (SVL) was slightly different between the sexes. We recorded weakly expressed sexual size dimorphism: the snout-vent-length of the males was slightly bigger (SDI = -0.01). Sexual maturity was attained between the second and the fourth year of life in both sexes. The age ranged from 3 to 11 years in females and from 3 to 12 years in males. The mean SVL was 65.33 ± 3.06 mm in females and 66.59± 3.76 mm in males. The mean age was 6.67 ± 2.63 years in females and 6.47 ± 2.75 years in males. There was no statistically significant difference in mean age between the sexes. [ABSTRACT FROM AUTHOR]

Copyright of Journal of the Institute of Science & Technology / Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi is the property of Igdir University, Institute of Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Academic Studies of Turkish-Islamic Civilization / Türk Islam Medeniyeti Akademik Arastirmalar Dergisi (Timad) is the property of Necmettin Erbakan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: Breast cancer is one of the most common malignancies in the world that leads to women's death. Proteasomes are large protein molecules that remove damaged or redundant proteins from the body through an enzyme called proteolysis. The 26S proteasome complex participates in the destruction of various proteins, regulates cellular mechanisms, and abnormalities in the regulation are linked to the development of cancer. Proteasome inhibitors block the activity of proteasomes, which are responsible for breaking down proteins and regulating gene expression through various signaling pathways. Many proteasome inhibitors have been developed by targeting the 26S proteasome complex for antitumor effects. These proteasome inhibitors have shown anticancer action by activating apoptosis in different tumor types. This study aimed to investigate the anticancer activity of a unique molecule with proteasome inhibitory properties that contains a tetrazole and oxadiazole ring on breast cancer cells. Method: In this study, ER+ breast cancer cells (MCF-7) were used. Cell viability was analyzed by MTT assay, and the half-maximal inhibitory concentration (IC50) value with the most effective time was determined. The apoptosis was detected by flow cytometry using Annexin V/PI in addition to Acridine Orange/Ethidium Bromide (AO/EB) double staining. Results: Cell viability results revealed that a new designed proteasome inhibitor induced cytotoxicity in ER+ breast cancers best at 72 hrs. However, the results showed that inhibitor containing tetrazole and oxadiazole rings has a lower IC50 value (200 µM) compared to inhibitor with only tetrazole. Flow cytometry analysis and AO/EB staining results also supported the viability data. Conclusion: The results of this study showed that proteasome inhibitor containing a tetrazole ring has some anti-cancer effect, but the addition of an oxadiazole ring to the molecule increases cell death caused by the inhibitor. [ABSTRACT FROM AUTHOR]

We examine three key issues related to flexibility in planning: the first is to understand how flexibility in planning emerges and to define its content; the second relates to how flexibility is formed in planning practices; and the third is to examine the outcomes of flexibility in planning practices. While focusing on the production of large-scale housing projects in Turkey, we examine the emergence of flexibility in planning in Turkey, the extent of this flexibility, how flexibility in Turkey is defined in its planning practices and the outcomes of such planning practices. We base our examination on two projects in Istanbul, one in a newly developing area and the other in an urban renewal area. Some lessons from our research will be relevant to other developing countries that have similar dynamics. [ABSTRACT FROM AUTHOR]

In this paper we introduce the class of m-valent Janowski close to convex harmonic functions. Growth and distortion theorems are obtained for this class. Our study is based on the harmonic shear methods for harmonic functions. [ABSTRACT FROM AUTHOR]

Let f(z) = a1z + a1z2 + … , a1 ≠= 0, be regular in ιzι < 1 and have there no zeros except at the origin. Reade ([3]) and the Sakaguchi ([2]) showed that a necessary and sufficient condition for f(z) to be a member of the class C(k) is that f(z) has a representation of the form f(z) = s(z)(p(z))k where s(z) is a regular function starlike with respect to the origin for ιzι < 1, k is a positive constant, and p(z) is a regular function with positive real part in ιzι < 1. The class of close-to-star functions introduced by Reade ([4]) is equivalent to C(1). In this paper we define the class C(k, A,B) (-1 ≤ B < A ≤ 1, k is positive constant) which contains the functions of the form f(z) = s(z)(p(z))k where s(z) is a regular Janowski starlike function, and p(z) is a regular function with positive real part in ιzι < 1. The aim of this paper is to give some properties and distortion theorems for this class. [ABSTRACT FROM AUTHOR]