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This work improves the systematic approach proposed in previous papers, aimed at defining design criteria specific for powder metallurgy (PM) parts subject to wear in application. Dry rolling-sliding tests have been performed on PM steels obtained under different process conditions, and the results have been used as a knowledge base in the proposed design procedure to evaluate the effect of the material variables (porosity and microhardness) and geometrical parameters (contact length) on wear resistance. The failure criterion considered here to ensure the functionality provides to compare the wear thickness with a value deriving from the dimensional tolerances. If the failure criterion is not matched, then a change in the material variables and/or geometrical parameters is proposed. The occurrence of plastic deformation and/or brittle contact at the surface region is also considered. Examples of application show that the most significant improvement is obtained by modifying both material variables and geometrical parameters. [ABSTRACT FROM AUTHOR]

We report 1000-transistor-level monolithic circuit integration of sub-30-nm gate-recessed E/D GaN high-electron-mobility transistors with fT and fmax above 300 GHz. Simultaneous fT/fmax of 348/340 and 302/301 GHz for E- and D-mode devices, respectively, was measured, representing a 58% increase in fT compared with our previous report, due to improved management of RC parasitic delay. Three-terminal E- and D-mode breakdown voltage of 10.7 and 11.8 V, respectively, is limited by gate-drain breakdown. [ABSTRACT FROM AUTHOR]

The article talks about bullous pemphigoid (BP) is a major autoimmune blistering skin disorder. It is mentioned that in BP majority of the autoantibodies (autoAbs) target the juxtamembranous extracellular NC16A domain of hemidesmosomal collagen XVII (COL17). The article discusses the connection between between BP and diabetes mellitus (DM) and how Dipeptidyl peptidase (DPP)-IV inhibitors causes BP.

This article describes a case control study evaluating the relationship between cutaneous melanoma and the residential use of pesticides. A hospital-based study of melanoma was conducted on subjects aged more than 18 years who were admitted in a hospital of central south Italy, Rome, during the period of May 2001 to May 2003. A total of 304 patient, with new histologically confirmed diagnosis of primary malignant cutaneous melanoma, were studied. In a multivariate model, considering sun exposure, phenotypic traits, number of nevi and the use of pesticides, duration of pesticides use was associated with 4 times the risk for melanoma.