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The pathogenic role of invasive fungal infections (IFIs) has increased during the past two decades in Latin America and worldwide, and the number of patients at risk has risen dramatically. Working habits and leisure activities have also been a focus of attention by public health officials, as endemic mycoses have provoked a number of outbreaks. An extensive search of medical literature from Latin America suggests that the incidence of IFIs from both endemic and opportunistic fungi has increased. The increase in endemic mycoses is probably related to population changes (migration, tourism, and increased population growth), whereas the increase in opportunistic mycoses may be associated with the greater number of people at risk. In both cases, the early and appropriate use of diagnostic procedures has improved diagnosis and outcome. [ABSTRACT FROM AUTHOR]

Objective. The purpose of the present study was to determine the associations of cold pressor test (CPT) cardiovascular reactivity with gestational age at birth and neonatal size in normotensive pregnant women. Methods. Seventy (70) healthy pregnant women were enrolled. The CPT consisted of introducing the patients' hands in cold water (4°C) for 3 min. An automatic oscillometric device was used to record blood pressure (BP) every minute for the following 5 min. Perinatal results were correlated with CPT findings. Results. Vascular reactivity assessed by CPT was higher in pregnant hypertensive women and in women with a hypertensive family history. Mean BP increases caused by CPT showed a significant negative correlation for gestational age (r = -0.58, p < 0.001) and cephalic perimeter (r = -0.57, p = 0.03). Diastolic BP increases caused by CPT were negatively correlated with newborn weight (r = -0.78, p < 0.001). Predictable newborn weight, gestational age, and cephalic perimeter were 4046 (47 x diastolic BP increase), 40.2 (0.07 x mean BP increase), and 35.8 (0.09 x mean BP increase), respectively. Conclusions. Results show that every mm Hg diastolic BP increase in response to CPT was correlated with a 47-g decrease in the newborn normal weight. Furthermore, every mean mm Hg BP increase in response to CPT was associated with a 0.07-week decrease in the newborn normal gestational age and a 0.09-cm decrease in the normal cephalic perimeter at birth. [ABSTRACT FROM AUTHOR]