1. A 3,5-dinitropyridin-2yl Substituted Flavonol-based Fluorescent Probe for Rapid Detection of H2S in Water, Foodstuff Samples and Living Cells.
- Author
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Hong, Lai-Xin, Zhang, Rong-Lan, and Zhao, Jian-She
- Subjects
FLUORESCENT probes ,FOOD spoilage ,STOKES shift ,ELECTRIC potential ,WATER sampling - Abstract
A novel flavonol-based fluorescent probe, Fla-DNT, has been synthesized for the rapid and specific detection of H
2 S. Fla-DNT exhibits excellent selectivity and anti-interference properties, a short response time (4 min), large Stokes shift (138 nm), and low detection limit (1.357 µM). Upon exposure to H2 S, Fla-DNT displays a remarkable increase in fluorescence intensity at 542 nm. Meanwhile, the recognizing site of H2 S was predicted through Electrostatic potential and ADCH charges calculations, while the sensing mechanism of H2 S was determined via HRMS analysis and DFT calculation. More importantly, the probe owes multiple applications, such as a recovery rate ranging from 92.00 to 102.10% for detecting H2 S in water samples, and it can be fabricated into fluorescent strips to track H2 S production during food spoilage by tracking color changes, thereby enabling real-time monitoring of food freshness. The bioimaging experiments demonstrate the capability of Fla-DNT to detect both endogenous and exogenous H2 S in living cells. These results provide a reliable method and idea for H2 S detection in complex environments. [ABSTRACT FROM AUTHOR]- Published
- 2024
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