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1. Folding induced supramolecular assembly into pH-responsive nanorods with a protein repellent shell.

Author

Otter, R., Klinker, K., Spitzer, D., Schinnerer, M., Barz, M., and Besenius, P.

Subjects
SUPRAMOLECULAR chemistry, PH effect, NANORODS
Abstract

We report the synthesis of ABA′ triblock peptide–polysarcosine–peptide conjugates featuring two complementary phenylalanine–histidine pentapeptide strands A/A′. These sequences encode for antiparallel β-sheet formation into folded conjugates, which promote the self-assembly into polysarcosine-shielded core–shell nanorods. These do not cause aggregation of serum proteins in human blood plasma underlining an enhanced stability. [ABSTRACT FROM AUTHOR]

Published
2018
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