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1. Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD.

Author

Tempel, Wolfram, Rabeh, Wael M., Bogan, Katrina L., Belenky, Peter, Wojcik, Marzena, Seidle, Heather F., Nedyalkova, Lyudmila, Tianle Yang, Sauve, Anthony A., Hee-Won Park, and Brenner, Charles

Subjects
EUKARYOTIC cells, NICOTINAMIDE, PHOSPHORYLATION, ENZYMES, CHEMICAL reactions
Abstract

Eukaryotic nicotinamide riboside kinase (Nrk) converts nicotinamide riboside to NAD+ by phosphorylation and adenylylation. The structures of this enzyme bound to several substrates lead to identification of new pathways to NAD+ [ABSTRACT FROM AUTHOR]

Published
2007
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