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Background: The aim of the study was to conduct a comprehensive performance evaluation of the Mindray CX-9000 fully automated coagulation analyzer for the detection of the seven coagulation items. Methods: The performance of activated partial thromboplastin time (APTT), prothrombin time (PT), fibrinogen (FIB), thrombin time (TT), D-dimer (D-D), fibrinogen degradation product (FDP), and antithrombin? (AT) was validated for precision, linear range, carryover contamination rate, reference interval validation, inter-method agreement, and anti-interference ability. Results: The intra-and inter-precision (coefficient of variation, CV%) of all seven items was less than the target CV%; the carryover contamination rates for different concentrations and between items were < 10%. The slope of the linear regression equation for the theoretical and measured values of the linear range was within 1 ± 0.05 and R = 0.975. The reference interval quoted from the manufacturer's reference interval passed = 95%. The CX- 9000 was compared with the results of the reference instrument STAGO R MAX (STA-R MAX) and the p-values for all items ranged from 0.822 to 0.987. Within the concentration range claimed by the manufacturer, the interference errors produced by all items met the manufacturer's claimed criteria, except for triglycerides which produced interference errors > 10% for the FIB, D-D, FDP, and bilirubin which produced interference errors for the FIB and D-D assays. Conclusions: The CX-9000 automatic coagulation analyzer has good stability and repeatability, a wide linear range of detection, low carryover contamination rate, and high resistance to interference, making it suitable for the testing of clinical specimens. [ABSTRACT FROM AUTHOR]

A 5-year-old Mongolian mare (Equus caballus Linnaeus, 1758) was observed to have corneal opacity and excessive ocular discharge. An ophthalmic examination revealed a moving thread-like cylindrical worm in the anterior chamber of the right eye. The parasite was successfully removed surgically. The worm was observed under light microscopy and confirmed as Setaria digitata by 12S rRNA gene amplification and sequencing. Phylogenetic analysis demonstrated similarity with Setaria digitata in the National Center for Biotechnology Information (NCBI) GenBank database isolated from other Asian countries. This report is the first confirmed case of equine ocular setariasis by molecular diagnosis in China, which may indicate its presence in livestock and promote research on its epidemiology. [ABSTRACT FROM AUTHOR]

Objective: Although several studies report a relationship between breakfast consumption and physical fitness, results are inconsistent and lack evidence in young adults. The objective of this study was to investigate the relationship between frequency of breakfast consumption and physical fitness among college students. Methods: This cross-sectional study investigated 10,125 Chinese college students (6251 male, 3874 female participants) who underwent physical examinations in 2015. Breakfast consumption was assessed using a self-reported questionnaire. Physical fitness was evaluated by grip strength and 50-meter sprint. Results: After adjusting for confounding factors, a significantly positive association was observed between frequency of breakfast consumption and grip strength (p < .001 for both sexes). Frequent breakfast consumption also was associated with faster sprint times in male and female participants (p < .001, and .002 respectively). Conclusions: We found that frequent breakfast consumption is significantly associated with higher grip strength and faster sprint times in Chinese college students. [ABSTRACT FROM AUTHOR]