208 results on '"Silva, Manuela"'
Search Results
2. Coercion in psychiatry: psychometric validation of the Portuguese Staff Attitudes to Coercion Scale (SACS).
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Aluh, Deborah Oyine, Diaz-Milanes, Diego, Pedrosa, Barbara, Silva, Manuela, Grigaitė, Ugnė, Almeida, Carolina Rocha, de Almeida Mousinho, Maria Ferreira, Vieira, Margarida, Cardoso, Graça, and Caldas-de-Almeida, José Miguel
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EMPLOYEE attitudes ,MENTAL health services ,PSYCHOMETRICS ,RURAL health services ,PROFESSIONALISM - Abstract
Background: There is a growing recognition that staff attitudes toward coercion in mental health care may influence its application. This study presents the psychometric properties of the Portuguese version of the Staff Attitudes towards Coercion Scale (SACS) and describes mental health professionals' attitudes towards coercion in Portugal. Methods: Mental health professionals working in five Portuguese mental health services in urban and rural regions of Portugal were invited to complete a questionnaire comprising the SACS and a socio-demographic form. Psychometric analyses including construct validity and internal consistency were carried out using R software. Results: A total of 91 out of 119 questionnaires completed were valid for analysis. Fifty-seven (62.64%) respondents were female, with an age range of 24 to 69 years (M = 39.33; SD = 11.09). More than half of them were nurses (52.75%, n = 48), and a third were psychiatrists (36.26%, n = 33). A three-factor structure was confirmed and showed the best fit compared to previously proposed models with a cumulative explained variance of 59%. The Portuguese SACS exhibited adequate internal consistency for both the full-scale and subscales. The highest mean score was in the pragmatic attitude domain (20.60; SD = 3.37). A negative correlation was observed between the critical attitude domain and both age and years of experience (p < 0.05). Conclusion: A three-factor structure was confirmed and showed the best fit compared to previously proposed models. The Portuguese SACS showed excellent psychometric properties and is acceptable for assessing staff attitudes towards coercion. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Responding to the needs of survivors of intimate partner violence in Lithuania: perceptions of mental health and social care professionals.
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Grigaitė, Ugnė, Klidziūtė, Greta, Aluh, Deborah Oyine, Pedrosa, Bárbara, Santos-Dias, Margarida, Silva, Manuela, Cardoso, Graça, and Caldas-de-Almeida, José Miguel
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INTELLECT ,INTIMATE partner violence ,MENTAL health ,SOCIAL workers ,RESEARCH funding ,FOCUS groups ,MENTAL health services ,PRESUMPTIONS (Law) ,HELP-seeking behavior ,SOUND recordings ,THEMATIC analysis ,HEALTH planning ,ATTITUDES of medical personnel ,WOMEN'S health services ,SOCIAL support ,MEDICAL needs assessment ,DATA analysis software ,GENDER-based violence - Abstract
Around eight-out-of-ten survivors of domestic violence in Lithuania are women, and of those, eight-out-of-ten suffer violence specifically from their intimate partners (IPV). Women who experience IPV are at higher risk of having mental health conditions. This study aims to explore the perspectives of mental health and social care professionals regarding the provision of mental health support to IPV survivors in Lithuania. Four focus groups were conducted among 29 service providers from across the country. Audio-recordings were transcribed verbatim and analyzed thematically using MAXQDA software. The five main themes derived from the analysis reveal: 1) low levels of IPV awareness among IPV survivors who seek support with their mental health; 2) a lack of specialized training among professionals as a barrier to effective support; 3) a low prioritization on the national level; 4) little inter-sectoral collaboration which undermines the complexity of needed responses; 5) broader systemic problems. The provision of mental health support to IPV survivors lacks the recognition that IPV is gender-based violence and a major public (mental) health problem. The complexity of needed services is absent. Further research needs to explore the utilization of mental health services by IPV survivors and their perceptions concerning it. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Avoiding pits on the energy landscape – alternative strategies for stabilizing nateglinide co-amorphous systems.
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Silva, Joana F. C., Jasiurkowska-Delaporte, Małgorzata, Pereira Silva, Pedro S., Silva, Manuela Ramos, Eusébio, M. Ermelinda S., and Rosado, Mário T. S.
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BROADBAND dielectric spectroscopy ,TRYPTOPHAN ,GLASS transition temperature ,AMORPHOUS substances ,POLYMORPHISM (Crystallography) ,POTENTIAL energy - Abstract
Amorphous solid phases can be represented by shallow basins in the potential energy hypersurface. Glasses formed by substances with prolific crystal polymorphism, such as nateglinide, an anti-diabetes drug, are susceptible to greater kinetical instability. Their energy landscape is characterized by deep pits in an accessible range, into which the supramolecular configuration can fall, when the amorphous solid relaxes to some crystalline polymorph. Alternative co-amorphization strategies are explored in this work to overcome the crystallization of nateglinide amorphous phases, namely by comparing two synthetic approaches, cryo-milling and quench-cooling, for a dual-drug system in combination with ranolazine. An alternative co-former, the essential amino-acid tryptophan, was also used for the synthesis of a cryo-milled nateglinide co-amorphous system. Enhanced kinetical stability for up to 8 months is achieved with both multicomponent systems. Their physico-chemical characterization in 3 molar ratios is accompanied by the study of their relaxation processes by broadband dielectric spectroscopy. Despite the higher glass transition temperatures obtained for the cryo-milled co-amorphous system with tryptophan, the co-amorphous salt system with ranolazine was found to have higher kinetical stability upon heating or ageing. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Challenges of the new Fiocruz Biodiversity and Health Biobank for preparedness and response to emerging and re-emerging infectious diseases.
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da Silva, Manuela, Stefanoff, Claudio Gustavo, Rezende Eneas, Paula Cristina, de Carvalho Villas Boas, Paulo, and Sobrinho do Nascimento, Carlos Roberto
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- 2024
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6. Prevalence and acceptability of psychological and/or economic intimate partner violence, and utilization of mental health services by its survivors in Lithuania.
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Grigaitė, Ugnė, Azeredo-Lopes, Sofia, Žeimė, Eglė, Slotkus, Paulius Yamin, Heitmayer, Maxi, Aluh, Deborah Oyine, Pedrosa, Bárbara, Silva, Manuela, Santos-Dias, Margarida, Cardoso, Graça, and Caldas-de-Almeida, José Miguel
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MEDICAL care use ,CROSS-sectional method ,INTIMATE partner violence ,MENTAL health services ,RESEARCH funding ,SOCIOECONOMIC factors ,LOGISTIC regression analysis ,FISHER exact test ,DESCRIPTIVE statistics ,ODDS ratio ,DIVORCE ,CONFIDENCE intervals ,DATA analysis software - Abstract
Background Lithuania has one of the highest averages in the European Union when it comes to psychological and/or economic intimate partner violence (PE-IPV). IPV survivors are several times more likely to have mental health conditions than those without IPV experiences. The aim of this article is to study the prevalence, characteristics and attitudes of PE-IPV survivors in Lithuania, and the predictors of them accessing mental health services. Methods A cross-sectional study based on a national survey representative of the adult population. The survey was implemented by a third-party independent market research company employing an online survey panel. Logistic regression models were used in the analysis. Results Almost 50% of women in Lithuania experience PE-IPV. Females are significantly more likely to experience it than males. The vast majority of women find PE-IPV unacceptable; however, only one-third of survivors seek any type of help. Only one-tenth approach mental health services, with divorcees being at higher odds of doing so. Conclusions Further research is needed to explore predictors and contextual factors of why IPV survivors seek mental healthcare, or not. Policy implications include the need to eliminate IPV and mental health stigma; develop accessible mental health services and effective treatment approaches. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Myrtucommulones and Related Acylphloroglucinols from Myrtaceae as a Promising Source of Multitarget SARS-CoV-2 Cycle Inhibitors.
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Mendonça, Simony Carvalho, Gomes, Brendo Araujo, Campos, Mariana Freire, da Fonseca, Thamirys Silva, Esteves, Maria Eduarda Alves, Andriolo, Bruce Veiga, Cheohen, Caio Felipe de Araujo Ribas, Constant, Larissa Esteves Carvalho, da Silva Costa, Stephany, Calil, Pedro Telles, Tucci, Amanda Resende, Oliveira, Thamara Kelcya Fonseca de, Rosa, Alice dos Santos, Ferreira, Vivian Neuza dos Santos, Lima, Julia Nilo Henrique, Miranda, Milene Dias, da Costa, Luciana Jesus, da Silva, Manuela Leal, Scotti, Marcus Tullius, and Allonso, Diego
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MYRTACEAE ,SARS-CoV-2 ,PLANT extracts ,VIRAL replication ,PARTIAL least squares regression - Abstract
The LABEXTRACT plant extract bank, featuring diverse members of the Myrtaceae family from Brazilian hot spot regions, provides a promising avenue for bioprospection. Given the pivotal roles of the Spike protein and 3CL
pro and PLpro proteases in SARS-CoV-2 infection, this study delves into the correlations between the Myrtaceae species from the Atlantic Forest and these targets, as well as an antiviral activity through both in vitro and in silico analyses. The results uncovered notable inhibitory effects, with Eugenia prasina and E. mosenii standing out, while E. mosenii proved to be multitarget, presenting inhibition values above 72% in the three targets analyzed. All extracts inhibited viral replication in Calu-3 cells (EC50 was lower than 8.3 µg·mL−1 ). Chemometric analyses, through LC-MS/MS, encompassing prediction models and molecular networking, identified potential active compounds, such as myrtucommulones, described in the literature for their antiviral activity. Docking analyses showed that one undescribed myrtucommulone (m/z 841 [M − H]− ) had a higher fitness score when interacting with the targets of this study, including ACE2, Spike, PLpro and 3CLpro of SARS-CoV-2. Also, the study concludes that Myrtaceae extracts, particularly from E. mosenii and E. prasina, exhibit promising inhibitory effects against crucial stages in SARS-CoV-2 infection. Compounds like myrtucommulones emerge as potential anti-SARS-CoV-2 agents, warranting further exploration. [ABSTRACT FROM AUTHOR]- Published
- 2024
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8. General Knowledge and Attitudes about Safety and Emergency Evacuation: The Case of a Higher Education Institution.
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Carvalhais, Carlos, Dias, Ricardo, Costa, Carla, and Silva, Manuela V.
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CIVILIAN evacuation ,UNIVERSITIES & colleges ,CULTURAL awareness ,TWO-dimensional bar codes ,ATTITUDE (Psychology) ,HYPERTENSIVE crisis - Abstract
The implementation of a safety culture and awareness of emergency issues in buildings has been growing in more developed societies. It is essential that all occupants know how to act in an emergency situation, particularly during an emergency evacuation. In higher education institutions (HEIs), which annually host not only their many employees, but also national and international students, it is essential to know and understand the knowledge, attitudes, and behaviors that the academic community demonstrates in this matter. This study aimed to characterize the perception of occupants regarding safety, specifically in the emergency evacuation phase, within the academic community of an HEI. In this observational cross-sectional study, data on general knowledge and attitudes regarding safety and actions during emergency situations were collected through an anonymous questionnaire targeting students, faculty, and non-teaching staff, which was sent via institutional email. Valid responses were received from 392 participants and then scored and assessed on different domains. The results obtained showed that, despite a reasonable average regarding the general level of knowledge, attitudes, and behaviors of the occupants on the subject, the community falls somewhat short in terms of training. It is noteworthy that approximately 64% of the sample has never received awareness or training related to emergency evacuation, and around 68% are unaware of the location of their institution's meeting/gathering point. Finally, by identifying the most common gaps, namely the training dimension, some simple measures could be improved, such as the dissemination of safety instructions accessible through QR codes placed in strategic locations or even conducting small drills during class sessions, as well as learning with simulation concerning different scenarios of emergency. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Engaging Young People in the Development of Innovative Nature-Inspired Technologies for Carbon Sequestration in Cities: Case Studies from Portugal.
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Moreira da Silva, Manuela, Ferreira, Lurdes, Sarmento, Teresa, and Selada, Catarina
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- 2024
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10. Microbiological Collections in Brazil: Current Status and Perspectives.
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Glienke, Chirlei, Petters-Vandresen, Desirrê Alexia Lourenço, Souto, Aline da Silva Soares, Marinoni, Luciane, and da Silva, Manuela
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BIOTECHNOLOGICAL microorganisms ,MICROBIAL diversity ,BIODIVERSITY conservation ,COLLECTIONS ,ENVIRONMENTAL protection ,ECOSYSTEMS - Abstract
As part of a Ministry of Science, Technology, and Innovation initiative, the Brazilian Societies of Botany, Microbiology, Virology, and Zoology conducted a comprehensive evaluation of biological collections in Brazil. This assessment aimed to gather insights into the current state of these collections, with the goal of providing support for future public policies, including financial subsidies and prioritization policies. In this context, we present the findings related to microbiological collections, essential to ex situ biodiversity conservation and crucial in supporting research, development, and innovation. A survey was distributed to public and private institutions across Brazil, yielding responses from 168 microbiological collections representing 79 different entities. Notably, 73 of these collections are affiliated with public research institutions and universities, underscoring the State's pivotal role in preserving and safeguarding Brazilian microbial diversity. The primary taxonomic groups encompass bacteria (found in 70.24% of collections) and fungi (comprising 52.98% of collections), sourced from diverse Brazilian ecosystems and biomes, including those that contain several type strains. Furthermore, the collections preserve microorganisms harboring biotechnological potential applicable to environmental protection, public health, industry, and agribusiness. Despite these promising economic and biotechnological prospects, our meticulous data analysis has revealed significant limitations and vulnerabilities, especially regarding physical infrastructure and human resources, emphasizing the urgent need for interventions to guarantee their sustainability. [ABSTRACT FROM AUTHOR]
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- 2024
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11. Use of coercion in mental healthcare services in Nigeria: Service providers' perspective.
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Aluh, Deborah Oyine, Ayilara, Olaniyi, Onu, Justus Uchenna, Pedrosa, Barbara, Silva, Manuela, Grigaitė, Ugnė, Santos-Dias, Margarida, Cardoso, Graça, and Caldas-de-Almeida, José Miguel
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ATTITUDES of medical personnel ,RESEARCH methodology ,INTERVIEWING ,LABOR demand ,MENTAL health ,QUALITATIVE research ,BEHAVIOR disorders ,RESEARCH funding ,SOUND recordings ,NURSES ,RESTRAINT of patients ,PATIENT-professional relations ,THEMATIC analysis ,DATA analysis software ,PHYSICIANS ,DEVELOPING countries ,MENTAL health services ,CONTROL (Psychology) ,PSYCHIATRIC hospitals ,PATIENT safety - Abstract
There is increasing advocacy to reduce coercive practices in mental healthcare. Little research has been done on the topic in developing countries. To explore what mental health professionals in Nigeria think about coercion, why it is used, and what contextual factors influence its use in mental healthcare services. Semi-structured interviews were carried out with 16 doctors and 14 nurses from two psychiatric hospitals in two regions of Nigeria. The audio-recorded interviews were analyzed thematically with the aid of MAXQDA software. Three broad categories relating to the perception of, reasons for, and barriers/facilitators to the use of coercion were derived. Coercion was viewed as being for the best interests of patients, a means to an end, and effective for achieving desired outcomes. Safety was both a reason to use a coercive measure and a deterrent to using specific coercive measures thought to be unsafe. The socio-cultural context, obsolete mental health legislation, staff shortages, and attitudes were factors influencing the use of coercion in mental healthcare. Coercion was perceived to be ultimately beneficial in mental health practice. There is need for a new mental health legislation and more resources for mental health care in Nigeria to address the problem of coercion. [ABSTRACT FROM AUTHOR]
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- 2024
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12. Challenges and Solutions for Sustainable Food Systems: The Potential of Home Hydroponics.
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Sousa, Rui de, Bragança, Luís, da Silva, Manuela V., and Oliveira, Rui S.
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The global food system is currently facing significant challenges that make it unsustainable and environmentally harmful. These challenges not only threaten food security but also have severe negative impacts on the environment. Efforts have been made to reform agrifood systems and align them with the built environment, but emerging obstacles have revealed the weaknesses in these systems, particularly in less self-sufficient countries. This review outlines the primary environmental problems associated with global agrifood systems and the challenges in promoting food security. It emphasizes that the increasing global population and urbanization need rational and equitable changes in food systems, including production, distribution, storage, and consumption. These changes should aim to minimize environmental impacts by protecting and efficiently utilizing natural resources such as air, water, soil, and biodiversity, reducing food loss and waste, and mitigating pollution that contributes to ecosystem degradation and climate change. In this context, hydroponics emerges as a sustainable, plant-based food production technique that can be employed as a solution in urban areas. It can be implemented in domestic microproduction systems, serving as a complementary alternative to conventional food production methods. This study also provides insights into the challenges that need to be addressed in order to enhance home hydroponic systems. The integration of hydroponics into urban food production offers the potential to tackle both food security and environmental sustainability issues, providing a path toward more resilient and efficient food systems. [ABSTRACT FROM AUTHOR]
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- 2024
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13. Tension On and Off in Atwood's Machine: The Advantage of Video Analysis.
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Campos, Nuno M., Domingos, Sérgio R., Silva, Pedro, and Silva, Manuela Ramos
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MECHANICS (Physics) ,PHYSICS education ,MACHINERY ,ELECTRONIC spreadsheets ,EQUATIONS of motion ,CORIOLIS force - Published
- 2024
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14. A qualitative integrative analysis of service users' and service providers' perspectives on ways to reduce coercion in mental health care.
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Aluh, Deborah Oyine, Onu, Justus Uchenna, Ayilara, Olaniyi, Pedrosa, Barbara, Silva, Manuela, Grigaitė, Ugnė, Dias, Margarida, Cardoso, Graça, and Caldas-de-Almeida, José Miguel
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MENTAL health services ,MENTAL health personnel ,HEALTH literacy ,MENTAL health facilities ,HEALTH care reform ,MENTAL health ,PSYCHIATRIC hospitals ,PUBLIC spaces - Abstract
Purpose: The movement to develop and implement non-coercive alternatives in the provision of mental health care is gaining momentum globally. To strengthen the basis of potential interventions that will be contextually relevant, and to complement the body of literature which is largely from high-income settings, the current study sought to explore the suggestions of service users and providers in Nigeria on how to reduce the use of coercive measures in mental health settings. Methods: Semi-structured interviews with 30 mental health professionals and four focus group discussions among 30 service users from two psychiatric hospitals in Nigeria were conducted. The data were analyzed thematically with the aid of MAXQDA. Results: The suggestions proposed by service users and mental health professionals were within the broad themes of communication, policies and legislation, and increased resources. Service users felt that improved communication, home consultations, non-legal advocates and clear rules and legislation would reduce the use of coercion, while service providers suggested increased public mental health literacy, better interpersonal relationships with patients, increased resources for mental health care, more research on the topic and regulation of coercive measures. Conclusion: Many of the suggestions from this study reinforce strategies already in place to decrease coercion in other settings. However, additional recommendations that are relevant to the study setting, such as enhancing public mental health literacy, mental health legislation reform and increasing access to mental health services, deserve further consideration. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Pesticide Application as a Risk Factor/Behaviour for Workers' Health: A Systematic Review.
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Moreira, Andreia and da Silva, Manuela Vieira
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PESTICIDES ,PACKAGING waste ,DISEASE risk factors ,PERSONAL protective equipment ,SCIENCE databases ,AGRICULTURAL laborers - Abstract
The main objective of this review was to determine the main risks that agricultural workers are exposed to during pesticide application, which may have a harmful effect on their health and on public health. This systematic review was based on the PRISMA guidelines. A search for articles was conducted in the Medline/PubMed, ScienceDirect, and Web of Science databases. Fifteen articles were selected considering their assessment of agricultural workers' knowledge, perceptions, attitudes, practices, and behaviours, identifying the main risks and risk factors for disease associated with the unsafe handling of pesticides. The main risk factors identified were age, education, pesticide safety training, farming experience, and contact with other farmers/intermediaries resulting in pesticide access. The most frequent risk behaviour was an application of pesticides without personal protective equipment (PPE), incorrect disposal of empty packaging and waste, and undervaluation of label information, as well as other unsafe practices. Multidisciplinary and more effective training must be delivered to enhance pesticide-safe usage. This will empower workers to adopt more conscious and safer behaviours while using pesticides. [ABSTRACT FROM AUTHOR]
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- 2023
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16. Beyond Patient Characteristics: A Narrative Review of Contextual Factors Influencing Involuntary Admissions in Mental Health Care.
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Aluh, Deborah Oyine, Aigbogun, Osaro, Ukoha-Kalu, Blessing Onyinye, Silva, Manuela, Grigaitė, Ugnė, Pedrosa, Barbara, Santos-Dias, Margarida, Cardoso, Graça, and Caldas-de-Almeida, José Miguel
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ONLINE information services ,PSYCHOLOGY information storage & retrieval systems ,VIOLENCE in the workplace ,RISK-taking behavior ,MEDICAL information storage & retrieval systems ,ATTITUDES of medical personnel ,SYSTEMATIC reviews ,PATIENTS ,HOSPITAL admission & discharge ,WAGES ,MEDLINE ,MENTAL health services - Abstract
Variations in the rates of involuntary admission (IA) reflect the influence of unexplained contextual variables that are typically too heterogeneous to be included in systematic reviews. This paper attempts to gather and analyze factors unrelated to the patients that have been linked to IA. The articles included in this review were selected by iteratively searching four electronic databases (PubMed, PsychINFO, EMBASE, and Web of Science). A total of 54 studies from 19 different countries and regions, including 14 European countries, the United States, Canada, China, Vietnam, and Taiwan, were selected. The factors were categorized as service-related factors, impactful events, seasonal and temporal factors, mental health legislation, staff factors, and public attitudes. The factors rarely act in isolation but rather interact and reinforce each other, causing a greater influence on IA. This paper explains how these factors present opportunities for robust and sustainable interventions to reduce IAs. The paper also identifies future directions for research, such as examining the effects of economic recessions. Enhancing global reporting standards is essential to validate future research and support further in-depth studies. The complexity of the factors influencing IA and the implicit role of society suggest that resolving it will require social change. [ABSTRACT FROM AUTHOR]
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- 2023
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17. Immunoglobulin A as a Key Immunological Molecular Signature of Post-COVID-19 Conditions.
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Sousa, Graziele F., Carpes, Raphael M., Silva, Carina A. O., Pereira, Marcela E. P., Silva, Amanda C. V. F., Coelho, Viktoria A. G. S., Costa, Evenilton P., Mury, Flávia B., Gestinari, Raquel S., Souza-Menezes, Jackson, Leal-da-Silva, Manuela, Nepomuceno-Silva, José L., Tanuri, Amilcar, Ferreira-Júnior, Orlando C., and Monteiro-de-Barros, Cintia
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IMMUNOGLOBULIN A ,COVID-19 pandemic ,COVID-19 ,IMMUNOGLOBULIN analysis ,SARS-CoV-2 - Abstract
COVID-19 has infected humans worldwide, causing millions of deaths or prolonged symptoms in survivors. The transient or persistent symptoms after SARS-CoV-2 infection have been defined as post-COVID-19 conditions (PCC). We conducted a study of 151 Brazilian PCC patients to analyze symptoms and immunoglobulin profiles, taking into account sex, vaccination, hospitalization, and age. Fatigue and myalgia were the most common symptoms, and lack of vaccination, hospitalization, and neuropsychiatric and metabolic comorbidities were relevant to the development of PCC. Analysis of serological immunoglobulins showed that IgA was higher in PCC patients, especially in the adult and elderly groups. Also, non-hospitalized and hospitalized PCC patients produced high and similar levels of IgA. Our results indicated that the detection of IgA antibodies against SARS-CoV-2 during the course of the disease could be associated with the development of PCC and may be an immunological signature to predict prolonged symptoms in COVID-19 patients. [ABSTRACT FROM AUTHOR]
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- 2023
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18. Experiences of care perceived by users of supported accommodations for people with serious mental disorders: Can they impact quality of life?
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Pedrosa, Bárbara, Cardoso, Graça, Azeredo-Lopes, Sofia, Aluh, Deborah, Grigaitė, Ugnė, Dias, Margarida, Silva, Manuela, and Caldas de Almeida, José
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MENTAL illness treatment ,PRIVACY ,PSYCHOTHERAPY patients ,CONFIDENCE intervals ,CLIENT relations ,CONVALESCENCE ,INTERVIEWING ,REGRESSION analysis ,PATIENT satisfaction ,PSYCHOSOCIAL factors ,QUALITY of life ,DESCRIPTIVE statistics ,MEDICAL ethics ,RESEARCH funding ,HOUSING ,STATISTICAL sampling ,SOCIODEMOGRAPHIC factors ,PSYCHIATRIC treatment ,PATIENT safety - Abstract
Background: To understand if supported accommodations (SA) are promoting the recovery of people with serious mental disorders, quality of life (QoL) is an important outcome. This study aimed to analyse the association between QoL and experiences of care in general and to identify specific experiences of care that are associated with QoL in users of SA. Methods: A random sample of users of 42 SA was interviewed to obtain standardized measures of QoL and personal experiences of care. The sample was also characterized according to sociodemographic and clinical aspects. Linear regressions models analysed the association between QoL and experiences of care, adjusting for potential confounders. Results include estimated regression coefficients, corresponding 95% confidence intervals and p-values. Results: The number of users interviewed was 272. The median QoL was 4.9 (2.3–6.8) out of 7. Although 84.9% of users were satisfied with the care received, only 16.2% felt involved in their treatment. Feeling safe (β =.73; 95% CI [0.22–1.24], p =.006) and having privacy (β =.42; 95% CI [0.09–0.75], p =.014) influenced QoL. Involvement in care (β =.44; 95% CI [0.13–0.74], p =.006), safety and privacy (β =.72; 95% CI [0.44–0.99], p = 8.38e-07) and user-professional relationship (β =.42; 95% CI [0.14–0.69], p =.003) were also associated with QoL. Conclusions: Feeling safe, having privacy, feeling involved in care and having good user-professional relationships influence the QoL of users. These findings have implications from the political and economic level to the organizational and individual levels. [ABSTRACT FROM AUTHOR]
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- 2023
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19. A atuação dos ocupantes dos cargos de secretário executivo nas IES: um estudo na Universidade Federal de Sergipe.
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dos Santos Souza, Elisangela Andrade, Ramos da Silva, Manuela, and Magno do Ouro Filho, Abimael
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CORPORATION secretaries ,FILING systems (Documents) ,ORGANIZATIONAL structure ,DESCRIPTIVE statistics ,PRACTICE of law - Abstract
Copyright of Revista Expectativa is the property of Revista Expectativa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2023
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20. Establishment of Cryptococcus neoformans and C. gattii as certified reference materials according to the requirements of ISO 17034:2016.
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Souto, Aline da Silva Soares, do Nascimento, Carlos Roberto Sobrinho, Rosas, Carla de Oliveira, Nishikawa, Marilia Martins, Villas Bôas, Maria Helena Simões, and da Silva, Manuela
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The use of certified reference materials (CRMs) is essential for laboratories that want to achieve reliable results because these materials have well-defined property values that enable the traceability of certain parameters in several areas. The production of CRMs for microbiological tests is complex, as there is a natural instability of microorganisms. The objective of this study was to establish Cryptococcus neoformans and Cryptococcus gattii as CRM, according to the requirements of ISO 17034. The availability of these materials will assist in the cryptococcosis diagnosis and support the academic community, since cryptococcosis is among the most lethal mycoses and affects more than one million people worldwide each year. C. neoformans CFRVS CRM 40,323 and C. gattii CFRVS CRM 40,324 batches, in skim milk at 20 %, were homogeneous and stable for 1 year. The materials were also stable at 4 °C, 25 °C and 35 °C, temperatures that simulate transportation conditions, for 7 days. In addition to the quantitative characterization, qualitative characterization of materials was conducted by observing melanin production, l-Canavanine Glycine Bromothymol Blue (CGB) Agar test and by RFLP-URA5 analyses. Certified property values and their associated uncertainties were assigned for each CRM. For C. neoformans CFRVS CRM 40,323, expanded uncertainty (U
CRM ) was 13 CFU mL−1 for 33 CFU mL−1 property value. For C. gattii CFRVS CRM 40,324, UCRM was 9.2 CFU mL−1 for 15 CFU mL−1 property value. Our study contributes to the development of CRM production in the microbiological field, whose supply is still very limited worldwide. [ABSTRACT FROM AUTHOR]- Published
- 2023
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21. Crystal Engineering to Avoid Pairing Dipolar Moments: The Case of 5-Nitrouracil, a Highly Polarizable Molecule.
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Ramos Silva, Manuela and Pereira da Silva, Pedro
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ELECTRIC dipole moments ,CRYSTALS ,NONLINEAR optics ,PHYSICISTS ,OPTICAL measurements - Abstract
5-nitrouracil is a polarizable molecule with a permanent electric dipole moment. Its molecular properties caught the attention of physicists working on nonlinear optics or optoelectronics, but the translation of the molecular assets to the crystalline solid has not been straightforward. This review compares all the known crystal structures incorporating the neutral or ionic 5-nitrouracil, or the two species concomitantly, discussing the effect of the packing in the optimization of the crystalline optical properties. Two new centrosymmetric 5-nitrouracilate salts are also reported for the first time, showing extensive hydrogen bonding between anions and cations. This review also gathers data from nonlinear optical measurements of non-centrosymmetric crystals and thermal stabilities of known polymorphs, showing that a neutral 5-nitrouracil molecule in acentric crystalline environment allows efficient blue-light generation. [ABSTRACT FROM AUTHOR]
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- 2023
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22. Prevalence of allergic rhinitis symptoms and associated factors in six-year-old children in a municipality in southern Brazil.
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Silva e Silva, Manuela, Traebert, Jefferson, da Silva Filho, Daniel José, and Traebert, Eliane
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- 2023
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23. Constitutive Behaviour of a Clay Stabilised with Alkali-Activated Cement Based on Blast Furnace Slag.
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Corrêa-Silva, Manuela, Cristelo, Nuno, Rouainia, Mohamed, Araújo, Nuno, and Miranda, Tiago
- Abstract
Alkaline cements have been extensively tested for soil stabilisation in the last decade. However, only a few studies have focused on the assessment of such performance by establishing the constitutive behaviour of the cement. In this paper, we focus on the mechanical behaviour, using triaxial testing of a clay with high water content stabilised with an alkali-activated binder and the subsequent prediction of the experimental stress–strain response using a kinematic hardening constitutive model initially developed for natural clays. Monotonic consolidated undrained triaxial tests were conducted on reconstituted and stabilised clay specimens cured for 28 days to evaluate the effects of cementation on the overall shear behaviour. Alkali-activated binder was synthetised from blast furnace slag and sodium hydroxide. Scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) were performed to study the microstructure, whereas leachate analyses were performed after 28 and 90 days of curing to investigate the contamination potential. The main product formed was calcium aluminosilicate hydrate (C-A-S-H) with a low CaO/SiO
2 ratio, and no risk of soil contamination was found. The compressibility and undrained shear strength in the pre-yield state was found to be independent of the initial mean effective stress (p'0 ), unlike what was observed in the post-yield state, where the shear strength seemed to be affected by p'0 . The model provided reliable predictions of the experimental results and captured the main features of the artificially cemented clay for the tested p'0 range. Such studies are fundamental to establish adequate confidence in such alternative binders—an essential aspect if their use is to become widespread in the near future. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
24. SARS-CoV-2 Spatiotemporal Genomic and Molecular Analysis of the First Wave of the COVID-19 Pandemic in Macaé, the Brazilian Capital of Oil.
- Author
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da-Costa-Rodrigues, Bruno, Cheohen, Caio, Sciammarella, Felipe, Pierre-Bonetti-Pozzobon, Allan, Ribeiro, Lupis, Nepomuceno-Silva, José Luciano, Medeiros, Marcio, Mury, Flávia, Monteiro-de-Barros, Cintia, Lazoski, Cristiano, Leal-da-Silva, Manuela, Tanuri, Amilcar, and Nunes-da-Fonseca, Rodrigo
- Subjects
COVID-19 pandemic ,GENOMICS ,SARS-CoV-2 ,WAVE analysis ,VIRUS diseases - Abstract
The SARS-CoV-2 virus infection led to millions of deaths during the COVID-19 pandemic. Hundreds of workers from several other Brazilian cities, as well as from other countries, arrive daily in Macaé to work in the oil supply chain, making this city a putative hotspot for the introduction of new viral lineages. In this study, we performed a genomic survey of SARS-CoV-2 samples from Macaé during the first outbreak of COVID-19, combined with clinical data and a molecular integrative analysis. First, phylogenomic analyses showed a high occurrence of viral introduction events and the establishment of local transmissions in Macaé, including the ingression and spread of the B.1.1.28 lineage in the municipality from June to August 2020. Second, SARS-CoV-2 mutations were identified in patients with distinct levels of COVID-19 severity. Third, molecular interactions of the mutated spike protein from three B.1.1.33 local samples and human ACE2 showed higher interactions than that of the wild-type spike protein from the ancestral virus. Altogether, these results elucidate the SARS-CoV-2 genomic profile in a strategic Brazilian city and further explore the functional aspects of SARS-CoV-2 with a characterization of emerging viral mutations associated with clinical data and the potential targets for drug development against SARS-CoV-2. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
25. Urban Wastewater Reuse for Citrus Irrigation in Algarve, Portugal—Environmental Benefits and Carbon Fluxes.
- Author
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Moreira da Silva, Manuela, Resende, Flávia C., Freitas, Bárbara, Aníbal, Jaime, Martins, António, and Duarte, Amílcar
- Abstract
Water scarcity is increasing in the Mediterranean and alternative sources of water are needed to meet food production needs, protect the environment and reduce the effects of climate change. Currently, many urban wastewater treatment plants (WWTP) produce high volumes of treated effluents which can be an alternative source of water for agriculture irrigation, since they fulfill the quality requirements for crops and the environment. This work analyzed the quantity and quality of a treated effluent produced by an urban WWTP in Algarve, and the environmental benefits of its use on the irrigation of a citrus orchard, as an alternative to groundwater. Carbon dioxide emissions related to orange production were quantified and the orchard's potential to sequester CO
2 was estimated. The reuse of this urban wastewater is revealed to be technologically feasible and environmentally advantageous, avoiding the overexploitation of the local aquifer and preventing the eutrophication of aquatic ecosystems, contributing to the improvement of soil characteristics and decreasing the carbon emissions in orange production. Furthermore, it was found that during the five-month experimental period, the citrus orchard sequestered 87.5% of the CO2 e emitted by WWTP in the effluent treatment, converting 72,623 kg of sequestered CO2 into orange biomass. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
26. ANÁLISES ARQUITETÔNICAS AO SUL DA AMÉRICA DO SUL: Experiência com alunos de Arquitetura e Urbanismo.
- Author
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Pedreira Del Fiol, Paula, Rocha, Eduardo, Martins Nogueira, Amanda, Silveira Wurch, Ana Laura, Melo Molina, Brunno, de Quadros Nicolao, Camila, Manta Vilela, Felipe, Lima Pinheiro, Fellipe, Peres Fernandes, Fernanda, Dutra da Silveira, Isadora Garcia, da Cruz Lopes, Julia, Moreira de Ávila, Júlia, Bittencourt Ramos, Laura, Mascarenhas Ferreira, Laura, Tiefensee Ribeiro, Luísa, de Souza Peglow, Luiza, Martinez da Silva, Manuela, Camargo da Cruz, Maria Laura, Gottems Vendrusculo, Paula, and Silvestre Silva, Vitória Maria
- Published
- 2022
- Full Text
- View/download PDF
27. O trabalho remoto emergencial em instituição federal de ensino superior na perspectiva dos ocupantes do cargo de secretário (a) executivo (a).
- Author
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da Silva Pereira, Sueli Maria, da Silva, Manuela Ramos, dos Santos, Maria Madalena Bispo, and da Silva, Hinara Beatriz Oliveira
- Abstract
Copyright of GeSec: Revista de Gestao e Secretariado is the property of Sindicato das Secretarias e Secretarios do Estado de Sao Paulo (SINSESP) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
28. Cystic fibrosis and jejunoileal atresia: A clinical case.
- Author
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Cunha, Sara Bernardes da, Rasteiro, Cátia, Silva, Manuela, Dias, Mariana, Araújo, Célia, and Ramalho, Carla
- Subjects
CYSTIC fibrosis ,HUMAN abnormalities ,PULMONARY atresia ,INTESTINES - Abstract
We present a case report of a fetal diagnosis of cystic fibrosis after ultrasound abnormalities. After delivery, a type 3A intestinal atresia was diagnosed. Segmental enterectomy with end‐to‐end anastomosis was performed. This case report highlights the diagnosis complexity of a fetal intestinal atresia associated with cystic fibrosis. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
29. Barriers to mental health services utilisation in Portugal – results from the National Mental Health Survey.
- Author
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Silva, Manuela, Antunes, Ana, Azeredo-Lopes, Sofia, Cardoso, Graça, Xavier, Miguel, Saraceno, Benedetto, and Caldas-de-Almeida, José Miguel
- Subjects
MENTAL illness treatment ,HEALTH policy ,HEALTH services accessibility ,CONFIDENCE intervals ,SUBSTANCE abuse ,ECONOMIC status ,FUNCTIONAL status ,HELP-seeking behavior ,MEDICAL care use ,QUESTIONNAIRES ,EMPLOYMENT ,HEALTH attitudes ,DESCRIPTIVE statistics ,SOCIODEMOGRAPHIC factors ,LOGISTIC regression analysis ,STATISTICAL models ,MARITAL status ,ODDS ratio ,ANXIETY ,MENTAL health services ,EDUCATIONAL attainment ,ADULTS - Abstract
The treatment gap for mental disorders remains a challenge worldwide. Identifying reasons for nontreatment may contribute to reducing this gap. To evaluate sociodemographic and clinical factors associated with use and barriers to treatment in Portugal. Data from the 2009 National Mental Health Survey were used. Participants reported 12-month treatment and reasons for nontreatment. Logistic regression models analysed the association between sociodemographic (education; employment; income; marital status) and clinical variables (mental disorder diagnosis; disability) with treatment and type of barriers (low perceived need; structural; attitudinal). The majority of participants with a mental disorder was not treated. Treatment was more common among participants with mood disorders (OR = 4.19; 95% CI: 2.72–6.46), and disability (OR = 2.43; 95% CI: 1.33–4.46), and less common among single participants (OR = 0.38; 95% CI: 0.20–0.70) and those with basic/secondary education (OR = 0.42; 95% CI: 0.24–0.73). Attitudinal barriers were more likely among participants with none/primary (OR = 2.90; 95% CI: 1.42–5.90) and basic/secondary education (OR = 1.70; 95% CI: 1.01–2.85), and less likely among those with substance use disorders (OR = 0.27; 95% CI: 0.10–0.70). Low perceived need was higher among single people (OR = 1.77; 95% CI: 1.01–3.08), and lower among those with anxiety (OR = 0.50; 95% CI: 0.28–0.90) and mood disorders (OR = 0.16; 95% CI: 0.09–0.30). Unemployed participants had higher odds of reporting structural barriers (OR = 3.76; 95% CI: 1.29–10.92). This study identifies factors associated with nontreatment, providing useful evidence to develop policies and effective interventions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
30. Trajetória da produção acadêmica da área de secretariado executivo em periódico científico no período 2010-2018.
- Author
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Machado, Taynara, Silva, Manuela, and do Ouro Filho, Abimael Magno
- Subjects
SCIENTIFIC knowledge ,LABOR market ,BACHELOR'S degree ,EMOTIONAL intelligence ,RESEARCH personnel - Abstract
Copyright of Revista Expectativa is the property of Revista Expectativa and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
31. Grain Transcriptome Dynamics Induced by Heat in Commercial and Traditional Bread Wheat Genotypes.
- Author
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Tomás, Diana, Viegas, Wanda, and Silva, Manuela
- Subjects
HEAT shock proteins ,GENOTYPES ,RNA synthesis ,TRANSCRIPTOMES ,GENETIC variation ,WHEAT ,IRON deficiency - Abstract
High temperature (HT) events have negative impact on wheat grains yield and quality. Transcriptome profiles of wheat developing grains of commercial genotypes (Antequera and Bancal) and landraces (Ardito and Magueija) submitted to heatwave-like treatments during grain filling were evaluated. Landraces showed significantly more differentially expressed genes (DEGs) and presented more similar responses than commercial genotypes. DEGs were more associated with transcription and RNA and protein synthesis in Antequera and with metabolism alterations in Bancal and landraces. Landraces upregulated genes encoding proteins already described as HT responsive, like heat shock proteins and cupins. Apart from the genes encoding HSP, two other genes were upregulated in all genotypes, one encoding for Adenylate kinase, essential for the cellular homeostasis, and the other for ferritin, recently related with increased tolerance to several abiotic stress in Arabidopsis. Moreover, a NAC transcription factor involved in plant development, known to be a negative regulator of starch synthesis and grain yield, was found to be upregulated in both commercial varieties and downregulated in Magueija landrace. The detected diversity of molecular processes involved in heat response of commercial and traditional genotypes contribute to understand the importance of genetic diversity and relevant pathways to cope with these extreme events. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
32. PRÁTICAS IMPLEMENTADAS PARA FORMAÇÃO EMPREENDEDORA NA EDUCAÇÃO BÁSICA.
- Author
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Cavalcante Carvalho, Agair Juliete and Ramos da Silva, Manuela
- Abstract
Copyright of Revista Pensamento Contemporâneo em Administração is the property of Universidade Federal Fluminense (Revista Pensamento Contemporaneo em Administracao) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
- Full Text
- View/download PDF
33. Capillarity and the rectangular hyperbola.
- Author
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Pinheiro, André O., Alvarinhas, José Pedro, and Silva, Manuela Ramos
- Subjects
CAPILLARITY ,HYPERBOLA ,CONIC sections ,MATHEMATICS education ,MATHEMATICS students - Abstract
It is generally agreed that making real-world connections in mathematics teaching increases students' motivation and interest and contributes to meaningful and permanent learning. In this paper we propose a simple and fast activity to find a rectangular hyperbola in real life and we show how to operate the data to retrieve a straight line. Since it deals with simple formulas, we believe that it can be useful in a high-school context, either in math or physics class. The activity consists of assembling a wedge with transparent plates (like glass photo frames), dipping it on a liquid and observing the rise of a hyperbola. Instructions are given on how to obtain the coordinates of the liquid/air interface and how to replot them as a straight line, using just a smartphone. For the physics class, an extension is proposed to measure the surface tension of the chosen liquid. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
34. Molecular testing and analysis of disease spreading during the emergence of COVID-19 in Macaé, the Brazilian National Capital of Oil.
- Author
-
Feitosa, Natália Martins, da Costa Rodrigues, Bruno, Petry, Ana Cristina, Nocchi, Keity Jaqueline Chagas Vilela, de Moraes Brindeiro, Rodrigo, Zilberberg, Carla, Monteiro-de-Barros, Cintia, Mury, Flavia Borges, de Souza-Menezes, Jackson, Nepomuceno-Silva, José Luciano, da Silva, Manuela Leal, de Medeiros, Marcio José, de Souza Gestinari, Raquel, da Silva de Alvarenga, Alessandra, Pozzobon, Allan Pierre Bonetti, Silva, Carina Azevedo Oliveira, das Graças dos Santos, Daniele, Silvestre, Diego Henrique, de Sousa, Graziele Fonseca, and de Almeida, Janimayri Forastieri
- Subjects
CAPITAL cities ,COVID-19 ,INFECTIOUS disease transmission ,COVID-19 pandemic ,UNIVERSITY & college administration - Abstract
The Brazilian strategy to overcome the spread of COVID-19 has been particularly criticized due to the lack of a national coordinating effort and an appropriate testing program. Here, a successful approach to control the spread of COVID-19 transmission is described by the engagement of public (university and governance) and private sectors (hospitals and oil companies) in Macaé, state of Rio de Janeiro, Brazil, a city known as the National Oil Capital. In 2020 between the 17th and 38th epidemiological week, over two percent of the 206,728 citizens were subjected to symptom analysis and RT-qPCR testing by the Federal University of Rio de Janeiro, with positive individuals being notified up to 48 h after swab collection. Geocodification and spatial cluster analysis were used to limit COVID-19 spreading in Macaé. Within the first semester after the outbreak of COVID-19 in Brazil, Macaé recorded 1.8% of fatalities associated with COVID-19 up to the 38th epidemiological week, which was at least five times lower than the state capital (10.6%). Overall, considering the successful experience of this joint effort of private and public engagement in Macaé, our data suggest that the development of a similar strategy countrywise could have contributed to a better control of the COVID-19 spread in Brazil. Quarantine decree by the local administration, comprehensive molecular testing coupled to scientific analysis of COVID-19 spreading, prevented the catastrophic consequences of the pandemic as seen in other populous cities within the state of Rio de Janeiro and elsewhere in Brazil. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
35. Relative motion made real.
- Author
-
Campos, Nuno M., Silva, Pedro, Domingos, Sérgio R., and Silva, Manuela Ramos
- Subjects
RELATIVE motion ,AIR resistance ,TABLET computers ,RELATIVE velocity ,PARTICLE acceleration - Abstract
The experiment consists of setting two carts in parallel motion and filming the movements, simultaneously with a fixed smartphone and with a moving smartphone riding along one of the carts (Fig. Smartphones have become widespread, and students carry them every day into the classroom. Sequence of frames extracted from one of the videos, depicting the overtaking of the object cart by the moving cart containing the smartphone. [Extracted from the article]
- Published
- 2023
- Full Text
- View/download PDF
36. The Impact of Structural Changes on Sound Pressure Levels in a Neonatal Intensive Care Unit.
- Author
-
CARVALHAIS, Carlos, RODRIGUES, Célia, XAVIER, Ana, SILVA, Manuela V., and SANTOS, Joana
- Subjects
SOUND pressure ,NEONATAL intensive care ,INTENSIVE care units ,TREATMENT effectiveness - Abstract
The design of neonatal intensive care units (NICU) influences both patient safety and clinical outcomes as well as the acoustic conditions. In NICU exposure to sound pressure levels above the recommended can affect both neonates and healthcare staff. This study aimed to evaluate the sound pressure levels and to assess noise perception of professionals in a NICU before and after structural modifications and layout redesign. The measurements were performed with a sound level meter. A questionnaire was given to staff before and after the intervention. The opinion of healthcare staff regarding noise in NICU was better after the intervention, when compared with the responses previously given. The results showed that noise levels were excessive in the NICU (before and after), exceeding the international recommendations, with the levels ranging between 46.6 dBA to 57.8 dBA before and 52.0 dBA to 54.0 dBA after intervention. Overall, there is a need for more research in order to verify the effectiveness of some actions and strategies to reduce the impact of noise in NICU. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
37. Effect of Diamond Bur Grit Size on Composite Repair.
- Author
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Valente, Lisia L., Silva, Manuela F., Fonseca, Andrea S., Münchow, Eliseu A., Isolan, Cristina P., and Moraes, Rafael R.
- Subjects
DENTAL resins ,DENTAL adhesive testing ,SCANNING electron microscopy ,ANALYSIS of variance ,DISSECTING microscopes ,SURFACE roughness measurement - Abstract
Purpose: This study investigated the effect of diamond bur grit size on the repair bond strength of fresh and aged resin composites. Materials and Methods: Blocks of microhybrid composite (Opallis, FGM) were stored in distilled water at 37°C for 24 h (fresh composite) or subjected to 5000 thermal cycles (aged composite). The surfaces were roughened using diamond-coated, flame-shaped carbide burs with medium grit (#3168), fine grit (#3168F), or extra-fine grit (#3168FF). The control group underwent no surface treatment. Surface roughness, water contact angle, and surface topography by scanning electron microscopy (SEM) were evaluated (n = 3). Samples were restored with resin composite and sectioned into beam-shaped specimens, which were subjected to microtensile bond testing. Failure modes were classified using a stereomicroscope. Data were statistically analyzed using the Student- Newman-Keuls test and two-way ANOVA, with significance set at p < 0.05. Results: Higher surface roughness was observed for groups treated with the medium- and fine-grit burs; aged composites were rougher than fresh composites. The water contact angle formed on the aged composite was lower than that on the fresh composite. The highest repair bond strength was observed for the fine-grit bur group, and the lowest was recorded for control. Interfacial failures were more predominant. SEM images showed that the surfaces treated with fine- and extra-fine-grit burs had a more irregular topography. Conclusion: Surface roughening of fresh or aged resin composites with diamond burs improved retention of the repair material. Fine-grit burs generally performed better than medium- and extra-fine-grit burs. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
38. Consumo colaborativo de moda: modelo de negócio guarda-roupa compartilhado para micro e pequenas empresas.
- Author
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Batista, Karen, Bezerra Lima, Lucas Gabriel, de Matos Martins, Ingrid, Moreira, Renan, and Ramos da Silva, Manuela
- Subjects
CORPORATE websites ,SMALL business ,COLLABORATIVE consumption ,BUSINESS models ,CONTENT analysis - Abstract
Copyright of Revista da Micro e Pequena Empresa is the property of Faculdade Campo Limpo Paulista and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
39. Factors associated with involuntary psychiatric hospitalization in Portugal.
- Author
-
Silva, Manuela, Antunes, Ana, Azeredo-Lopes, Sofia, Loureiro, Adriana, Saraceno, Benedetto, Caldas-de-Almeida, José Miguel, and Cardoso, Graça
- Subjects
INVOLUNTARY hospitalization ,PSYCHIATRIC hospital care ,MENTAL health services ,PSYCHIATRIC diagnosis ,WATERSHEDS - Abstract
Background: Identifying which factors contribute to involuntary psychiatric hospitalization may support initiatives to reduce its frequency. This study examines the sociodemographic, clinical, and contextual factors associated with involuntary hospitalization of patients from five Portuguese psychiatric departments in 2002, 2007 and 2012. Methods: Data from all admissions were extracted from clinical files. A Poisson generalized linear model estimated the association between the number of involuntary hospitalizations per patient in one year and sociodemographic, clinical, and contextual factors. Results: An increment of involuntary hospitalizations was associated with male gender [exp( β ^ ) = 1.31; 95%CI 1.06–1.62, p < 0.05], having secondary and higher education [exp( β ^ ) = 1.45; 95%CI 1.05–2.01, p < 0.05, and exp( β ^ ) = 1.89; 95%CI 1.38–2.60, p < 0.001, respectively], a psychiatric diagnosis of psychosis [exp( β ^ ) = 2.02; 95%CI 1.59–2.59, p < 0.001], and being admitted in 2007 and in 2012 [exp( β ^ ) = 1.61; 95%CI 1.21–2.16, p < 0.01, and exp( β ^ ) = 1.73; 95%CI 1.31–2.32, p < 0.001, respectively]. A decrease in involuntary hospitalizations was associated with being married/cohabitating [exp( β ^ ) = 0.74; 95%CI 0.56–0.99, p < 0.05], having experienced a suicide attempt [exp( β ^ ) = 0.26; 95%CI 0.15–0.42, p < 0.001], and belonging to the catchment area of three of the psychiatric services evaluated [exp( β ^ ) = 0.65; 95%CI 0.49–0.86, p < 0.01, exp( β ^ ) = 0.67; 95%CI 0.49–0.90, p < 0.01, and exp( β ^ ) = 0.67; 95%CI 0.46–0.96, p < 0.05 for Hospital de Magalhães Lemos, Centro Hospitalar Psiquiátrico de Lisboa and Unidade Local de Saúde do Baixo Alentejo, respectively]. Conclusions: The findings suggest that involuntary psychiatric hospitalizations in Portugal are associated with several sociodemographic, clinical, and contextual factors. This information may help identify high-risk patients and inform the development of better-targeted preventive interventions to reduce these hospitalizations. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
40. Determinação de alergénios de amendoim e amêndoa em alimentos comercializados não pré-embalados.
- Author
-
Soares, Renata, Sousa, Carolina, Soares, Sílvia, Moreira, Andreia, Vieira da Silva, Manuela, and Freitas, Marisa
- Published
- 2024
- Full Text
- View/download PDF
41. COMPETÊNCIAS ORGANIZACIONAIS DESENVOLVIDAS PELA ESCOLA NACIONAL DE ADMINISTRAÇÃO PÚBLICA COMO ESCOLA DE GOVERNO (1986-2016).
- Author
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Ramos da Silva, Manuela and Mac-Allister Silva, Monica de Aguiar
- Subjects
ORAL history ,THEMATIC analysis ,PUBLIC administration ,PERFORMANCE ,PUBLIC sector ,HUMAN resources departments - Abstract
Copyright of Cadernos de Gestão Pública e Cidadania is the property of Fundacao Getulio Vargas, Escola Brasileira de Administracao Publica e de Empresas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
42. Payments for watershed ecosystem services in the Miringuava basin, Brazil: Mediating or exacerbating conflicts in peri-urban commons?
- Author
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Werner Weins, Niklas, de Oliveira Santos, Leticia Costa, Dreyer Silva, Manuela, Gadda, Tatiana, and Luiz da Silva, Christian
- Subjects
PAYMENTS for ecosystem services ,ENVIRONMENTAL organizations ,SOCIAL impact ,WATER supply ,WATER purification - Abstract
Copyright of Revista de Gestão Ambiental e Sustentabilidade (GeAS) is the property of Revista de Gestao Ambiental e Sustentabilidade / UNINOVE and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
- Full Text
- View/download PDF
43. Assessment of Four Portuguese Wheat Landrace Diversity to Cope With Global Warming.
- Author
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Tomás, Diana, Coelho, Luís Pinto, Rodrigues, José Carlos, Viegas, Wanda, and Silva, Manuela
- Subjects
GLOBAL warming ,ATTENUATED total reflectance ,WHEAT ,WHEAT breeding ,GRAIN yields - Abstract
Wheat is a dietary staple consumed worldwide strongly responsible for proteins and carbohydrate population intake. However, wheat production and quality will scarcely fulfill forward demands, which are compounded by high-temperature (HT) events as heatwaves, increasingly common in Portugal. Thus, landraces assume crucial importance as potential reservoirs of useful traits for wheat breeding and may be pre-adapted to extreme environmental conditions. This work evaluates four Portuguese landrace yield and grain composition through attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy, particularly protein content, and their responses to HT treatment mimicking a heatwave. Landraces showed distinct yield traits, especially plant height and first spike grain number, and a similar pattern in FTIR spectra, although revealing differences in grain components' proportions. Comparison between spectra band intensity indicates that Ardito has the highest protein-related peaks, contrary to Magueija, which appears to be the landrace with higher lipid content. In plants submitted to 1 week of HT treatment 10 days after anthesis, the first spike grain size and weight were markedly reduced in all landraces. Additionally, it was observed that a general increase in grain protein content in the four landraces, being the increment observed in Ardito and Grécia, is statistically significant. The comparative assessment of control and HT average FTIR spectra denoted also the occurrence of alterations in grain polysaccharide composition. An integrated assessment of the evaluations performed revealed that Ardito and Magueija landraces presented diverse yield-related characteristics and distinct responses to cope with HT. In fact, the former landrace revealed considerable grain yield diminution along with an increase in grain protein proportion after HT, while the latter showed a significant increase in spikes and grain number, with grain quality detriment. These results reinforce the relevance of scrutinizing old genotype diversity seeking for useful characteristics, particularly considering HT impact on grain production and quality. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
44. Atrazine, desethylatrazine (DEA) and desisopropylatrazine (DIA) degradation by Pleurotus ostreatus INCQS 40310.
- Author
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Lopes, Raquel de Oliveira, Pereira, Patrícia Maia, Pereira, Aline Ramalho Brandão, Fernandes, Keysson Vieira, Carvalho, Julia Finamor, França, Alexandre da Silva de, Valente, Richard Hemmi, da Silva, Manuela, and Ferreira-Leitão, Viridiana S.
- Subjects
PLEUROTUS ostreatus ,ATRAZINE ,ENDOENZYMES ,CYTOCHROME P-450 ,PEROXIDASE ,HERBICIDES ,SUGARCANE - Abstract
Atrazine is the most common herbicide applied in crops of economic relevance, such as sugar cane, soybean, and corn. Atrazine and its derivatives desethylatrazine (DEA) and desisopropylatrazine (DIA) are toxic to the environment, affecting animal and human health. Thus, this study aimed to evaluate the degradation of atrazine and its derivatives by the fungus Pleurotus ostreatus INCQS 40310, as well as the potential of the enzymes involved in this process. P. ostreatus INCQS 40310 was able to degrade atrazine (82%), DEA (71%), and DIA (56%) over 22 days of fungal cultivation. Proteomic analysis indicated the participation of hydrolases and peroxidases during the degradation process. Additionally, resting cells of the fungus were tested to verify the action of intracellular enzymes in the degradation process, suggesting the participation of cytochrome P450 enzymatic complex. Resting cells experiments promoted the degradation of 50% of atrazine, 36% of DIA, 30% of DEA. So far, this is the first work evaluating the biodegradation of DEA and DIA by fungus. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
45. Replacing HEMA with Alternative Dimethacrylates in Dental Adhesive Systems: Evaluation of Polymerization Kinetics and Physicochemical Properties.
- Author
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Aldrighi Münchow, Eliseu, Zanchi, Cesar Henrique, Aulo Ogliari, Fabrício, Gonçalves Souza e Silva, Manuela, Rubin de Oliveira, Isadora, and Piva, Evandro
- Subjects
DENTAL adhesives ,POLYMERIZATION research ,DENTAL resins ,METHACRYLATES ,DIMETHYLAMINOETHANOL - Abstract
Purpose: To evaluate the mechanical and physical properties of experimental HEMA-containing and HEMA-free resin adhesives. Materials and Methods: Experimental HEMA-free adhesives containing alternative dimethacrylates (bis-EMA 10 [B10], bis-EMA 30 [B30], PEG 400 [P400], PEG 1000 [P1000], PEG 400 UDMA [UP400]) were formulated and compared with a HEMA-containing adhesive (control). The adhesives were characterized by rheological analysis, polymerization kinetics (PK), water sorption (WS), and solubility (SL) tests. Flexural strength (FS) and flexural modulus (E) tests were performed under dry or wet conditions (distilled water or 70% ethanol solution). One-way and two-way ANOVA as well as Tukey's test were used to evaluate differences between groups (p < 0.05). Results: The control group showed the lowest viscosity and was the only one with a degree of conversion lower than 50%. The control and the P1000 adhesive showed the statistically significantly highest WS (p < 0.05). The control and the UP400 adhesive showed the highest FS and E, and the dry-stored specimens showed more improved mechanical strength than did the wet-stored specimens (p < 0.05). Conclusion: The physicomechanical properties of some of the HEMA-free adhesives were substantially improved when compared with those of the control, indicating that they could be potential monomers for the development of HEMA-free adhesive systems. [ABSTRACT FROM AUTHOR]
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- 2014
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46. Exploring socioeconomic and mental health trajectories during times of economic recession: a qualitative study with primary health care users and professionals.
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Antunes, Ana, Frasquilho, Diana, Zózimo, Joana Rocha, Silva, Manuela, Cardoso, Graça, Ferrão, João, and Caldas-de-Almeida, José Miguel
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ATTITUDE (Psychology) ,FOCUS groups ,INTERVIEWING ,RESEARCH methodology ,MEDICAL personnel ,MENTAL health ,MENTAL illness ,PRIMARY health care ,RECESSIONS ,SICK leave ,QUALITATIVE research ,SOCIOECONOMIC factors ,THEMATIC analysis ,PATIENTS' attitudes - Abstract
Background: The 2008 economic recession has been shown to affect populations' mental health due to deterioration of socioeconomic and living conditions. Concurrently, mental health problems may have constituted a vulnerability to wider social inequalities during this period. Aims: To explore perceptions and experiences of primary health care users and professionals regarding the relationship between mental health and socioeconomic position during the economic recession in Portugal. Method: Data were collected in three primary health care centres in Lisbon Metropolitan Area. Focus groups and semi-structured interviews were conducted with users and professionals, respectively. Interviews were audio-recorded, transcribed verbatim and underwent thematic analysis. Results: Two themes were obtained. The first comprised the relationship between changes in socioeconomic conditions (unemployment, precarious work conditions and financial hardship) and poor mental health. The second involved the consequences of experiencing mental health problems during the recession, namely disability, need of sick leave and early retirement. Conclusions: This study provided a comprehensive overview of the bidirectional relationship between socioeconomic conditions and mental health, emphasizing the need to develop policies to address the drivers of poor mental health during times of economic downturn and tackle the barriers faced by people with mental disorders to promote their full social inclusion. [ABSTRACT FROM AUTHOR]
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- 2020
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47. Conservation Policy: Helping or hindering science to unlock properties of plants and fungi.
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Williams, China, Walsh, Alexandra, Vaglica, Valentina, Sirakaya, Aysegül, Silva, Manuela, Dalle, Gemedo, Winterton, Deborah, Annecke, Wendy, Smith, Paul, Kersey, Paul J., Way, Michael, Antonelli, Alexandre, and Cowell, Carly
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PLANT-fungus relationships ,PLANT ecology ,MEDICINAL plants ,BIODIVERSITY conservation ,SOCIAL impact - Abstract
Societal Impact Statement: Biodiversity loss is happening at an unprecedented rate. Understanding and protecting biodiversity has never been more urgent, and scientific research is key to this. Fair and transparent access and benefit sharing policies enable research to take place, whilst supporting sustainable livelihoods of communities and ensuring benefits are shared. Current national legislation has been unevenly implemented and, in this article, we recommend frameworks be developed to standardize the provision and use of genetic resources for non‐commercial research. Summary: Access to genetic resources for scientific research is vital to support and promote the conservation and sustainable use of the world's biodiversity. The regulatory framework for research is stipulated by Access and Benefit Sharing (ABS) legislation at a national level, but other elements – legal transparency, respect, cooperation, and trust – are essential for its effective and sustainable implementation. Despite the intention of this "ABS regime" to protect natural resources and associated knowledge from misappropriation, several studies have questioned whether national regulatory approaches have led to constraints on research and conservation.We analyse evidence and provide case studies on how these regulations are affecting research. We find that the number of Internationally Recognized Certificates of Compliance (IRCC) of the Nagoya Protocol (NP), the key compliance mechanism of the ABS system, doubled in the six months prior to February 2020 and analyse why this may be the case.Additionally, a survey of the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) Authorities in 28 countries, found differences in the way the Registered Scientific Institute scheme is interpreted and used to facilitate scientific research.Our results suggest while the regulatory systems are perceived as hindering research and conservation, regulatory mechanisms enabling responsible research are becoming increasingly functional. We argue that functional and transparent systems are needed for both regulators and researchers, to ensure that non‐commercial research can continue smoothly, and present conclusions to support research for the benefit of all countries and partners involved, through appropriate frameworks for implementation and reporting. [ABSTRACT FROM AUTHOR]
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- 2020
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48. Biodiversity and patents: Overview of plants and fungi covered by patents.
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Simmonds, Monique S. J., Fang, Rui, Wyatt, Lilybelle, Bell, Elizabeth, Allkin, Bob, Forest, Felix, Wynberg, Rachel, Silva, Manuela, Zhang, Ben Gang, Shi Liu, Jiu, Dong Qi, Yao, and Demissew, Sebsebe
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BIODIVERSITY ,PATENTS ,PLANT ecology ,SOCIAL impact ,PLANT-fungus relationships - Abstract
Social Impact Statement: Patents can be used as a measure of innovation and to illustrate the commercial potential of plant and fungal biodiversity. The proportion of plant species named in patents represents only 6.2% of plant species, whereas the proportion of fungi is likely less than 0.4%. Fungi clearly justify further research. Innovation on a species usually drives more innovation on that species. We suggest that we should ensure that commercialization frameworks encourage studies on a greater diversity of plants and fungi. This could not only increase the range of biodiversity‐based products and associated income but also incentivize their conservation and encourage more fundamental research. Summary: In this review, patents are used as a measure of innovation, and data show that a low proportion of plant and fungal biodiversity is mentioned in patents. The proportion of plant species named in patents represents only 6.2% of plant species, whereas the proportion of fungi is most likely less than 0.4%. The number of species within a plant family mentioned in patents varies greatly. The following families having the greatest numbers: Asteraceae with 1,445 species (4.5% of species), Fabaceae with 1,299 species (5.8%), Poaceae with 1,008 species (8.5%), and Rosaceae with 718 species (12.7%). Case studies from Brazil, Ethiopia, and South Africa explore some of the controversies associated with patenting, especially when patents have not taken prior art into account. In contrast, a case study on plants and fungi used in traditional Chinese medicine illustrates their economic value and their potential to support new innovations. Innovative ways to use plant and fungal biodiversity has the potential to generate wealth, reduce poverty, improve human well‐being and in theory incentivize biodiversity conservation. International and national policies and laws that aim to facilitate equitable benefit‐sharing associated with access to and use of genetic diversity need to be reviewed to help facilitate innovation, as well as ensure that the rights of communities to use these resources are recognized and supported. [ABSTRACT FROM AUTHOR]
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- 2020
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49. Fiocruz Biological Collections: strengthening Brazil's biodiversity knowledge and scientific applications opportunities.
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da Silva, Manuela, Chame, Marcia, and Moratelli, Ricardo
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NATURAL history museums ,NATURAL history catalogs & collections ,INVERTEBRATES ,VASCULAR plants ,BIODIVERSITY - Abstract
Biological collections are central in understanding and preserving life on Earth. In Brazil, the most representative collections are kept by natural history museums, whose primary focus is in invertebrates, vertebrates and vascular plants. Only a few institutions keep repositories in different kingdoms. The Oswaldo Cruz Foundation (Fiocruz), established in 1900, is a strategic public health institution of the Ministry of Health of Brazil. As such, Fiocruz is responsible for a wide range of activities, from basic research to the development and production of vaccines, drugs, reagents and diagnostic kits. Its biological collections were soon established in the expeditions made by naturalists and physicians seeking integrated knowledge of the fauna, flora and tropical diseases. Since then, they have been part of the institutional policy. In a few decades, those collections were already in the forefront of basic and applied research on tropical parasitic and infectious diseases. Currently, they comprise thirty-three repositories representing part of the Brazilian diversity of bacteria, fungi, protozoa, helminths, arthropods, molluscs and plants of medical and environmental importance. Different methods of long-term preservation are applied for the conservation of this wide range of organisms represented by about 6 million specimens. Herein, we describe this range of collections and discuss their complementary role as repositories of groups not represented in other biological collections in Brazil. These valuable biological materials have been used in public health and medical research, as well as for technological development and innovation in Brazil. Parallel to this specific usage, Fiocruz biological collections have played and continue to play a unique and important role in understanding and conserving part of Brazil's biodiversity that is currently underrepresented in other biological and natural history collections in Brazil and South America. [ABSTRACT FROM AUTHOR]
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- 2020
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50. How did the use of psychotropic drugs change during the Great Recession in Portugal? A follow-up to the National Mental Health Survey.
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Silva, Manuela, Antunes, Ana, Azeredo-Lopes, Sofia, Cardoso, Graça, Xavier, Miguel, Saraceno, Benedetto, and Caldas-de-Almeida, José Miguel
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MENTAL health surveys ,PSYCHIATRIC drugs ,DRUG abuse ,DRUG utilization ,OLDER women - Abstract
Background: Research suggests that economic recessions might be associated with a higher use of psychotropic drugs, but literature is scarce and contradictory in identifying the most vulnerable groups. This study aims to assess possible changes in the use of psychotropic drugs due to the economic recession in Portugal, by comparing self-reported consumption in 2008/09 and 2015/16. Methods: Data from the World Mental Health Survey Initiative Portugal (2008/09) and the National Mental Health Survey Follow-Up (2015/16) were used (n = 911). McNemar's tests were performed to estimate changes in consumption of any psychotropic drug and of antidepressants, anxiolytics, and hypnotics/sedatives. Multiple Generalised Estimating Equations models with interaction effects were used to estimate the population odds of consuming psychotropic drugs according to year, gender and age. Results: An increase of 6.74% was estimated in the consumption of psychotropic drugs from 2008/09 to 2015/16. Population odds of consuming any psychotropic drugs in 2015/16 were estimated to be 1.5 times higher than in 2008/09 (OR = 1.50;95%CI:1.13–2.01), particularly for hypnotics/sedatives (OR = 1.60;95%CI:1.14–2.25). Women and older individuals presented higher odds of consuming any psychotropic drugs (OR = 2.79;95%CI:2.03–3.84, and OR = 1.80;95%CI:1.28–2.54), after adjusting for year of assessment and education. However, when evaluating the interaction effect of the year with gender and age, men and younger individuals reported higher odds of consuming any psychotropic drugs in 2015/16, when compared to 2008/09 (OR = 1.85;95%CI:1.08–3.17, and OR = 1.95;95%CI:1.32–2.90, respectively). Conclusions: The findings indicate that the period of economic recession was associated with an increased risk of psychotropic drugs use in Portugal. Consumption of psychotropic drugs remained higher among women and older individuals, but the results suggest that the economic crisis had a disproportionate impact on men and younger individuals. This identification of the most vulnerable population groups is useful to design effective and targeted public health interventions aimed at alleviating the effects of economic recessions. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
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