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A man in his 20s presented with a 2-week history of fever, fatigue and diarrhoea. On arrival to the emergency department, he had clinical findings of sepsis. The care team initially suspected sepsis secondary to bacterial colitis and administered antibiotics. Further workup including a stool PCR assay for gastrointestinal pathogens failed to establish a diagnosis, and he had no evidence of immune compromise. Colonoscopy revealed mucosal ulceration presumed to be ulcerative colitis. Histopathology obtained after discharge revealed severe colitis with cytomegalovirus (CMV) inclusions. Serological studies indicated a primary CMV infection. To our knowledge, this is the first report of a primary CMV infection presenting as severe colitis and systemic disease in a young immunocompetent patient without underlying disease. [ABSTRACT FROM AUTHOR]

This article describes the background and experiences of three graduate students who co-authored a print-based transmedia book during the summer of 2013. The article provides information about why the transmedia engineering book was designed and provides an overview of the book's creation process. The project was funded through a National Science Foundation grant awarded to the Department of Learning Technologies at a large North American university. The transmedia book focused on providing learning opportunities for middle school students taking part in the agricultural engineering process to solve authentic tasks through problem solving and technology. Quick Response (QR) codes, web resources, and fabrication manipulatives (2-dimensional cutter and 3-dimensional fabricator) were integrated into the content of the book. A companion website was created as a resource. [ABSTRACT FROM AUTHOR]