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Bronchopulmonary system diseases are on the first place among the causes of people's death. Most of methods for lung diseases diagnosis are invasive or not suitable for children and patients with severe disease. One of the promising methods of clinical diagnosis and disease activity monitoring of bronchopulmonary system is analyzing of human breath. Directly exhaled breath or exhaled breath condensate are using for human breaths analyzing. Analysis of human breath can apply for diagnostic, long monitoring and evaluation of efficacy of the treatment bronchopulmonary diseases. Differential diagnostic between chronic obstructive lung disease (COPD) and bronchial asthma is complicated because they have differences in pathogenesis. Analysis of human breath allows to explore features of COPD and bronchial asthma and to improve differential diagnostic of these diseases. Human breaths analyzing can apply for diagnostic dangerous diseases, such as tuberculosis, lung cancer. The analysis of breath air by spectroscopy methods is new noninvasive way for diagnosis of bronchopulmonary diseases.

Absorption spectra of breath air for 108 healthy persons, 28 patients with pulmonary tuberculosis and 56 patients with many a diseases were recorded using laser photoacoustic technique. It was ascertained that, as the breath air analysis result, pulmonary tuberculosis can be diagnosed.

Because of the shortcomings of existing methods of assessment of inflammation activity in the airways, the method of laser optic-acoustic spectroscopy of patients expired air considered using for this purpose. This method can be used to indirectly evaluate the activity of inflammation in the airways and as an additional criterion for the effectiveness of basic treatment in patients with asthma.