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Your search keyword '"Antonios Samiotakis"' showing total 4 results
Start Over Author "Antonios Samiotakis" Database Directory of Open Access Journals
4 results on '"Antonios Samiotakis"'

1. 1395 Targeting intracellular tumor antigens to Figureht cancer: discovery and development of functional and specific T-cell engagers against a MAGE-A4 pMHC

Author

Kate Gibson, Peter Bergqvist, Lauren Chong, Davide Tortora, Tim Jacobs, Patrick Farber, Ryan Blackler, Antonios Samiotakis, Harveer Dhupar, Craig Robb, Allison Goodman, Cindy-Lee Crichlow, Melissa Cid, Jessica Fernandes Scortecci, Rodrigo Goya, Eduardo Solano Salgado, Ping Xiang, Ahn Lee, Irene Yu, Gabrielle Conaghan, Nathalie Blamey, Vivian Li, Valentine de Puyraimond, Patrick Rowe, Kush Dalal, Stephanie K Masterman, Tara Fernandez, Raffi Tonikian, and Bryan C Barnhart

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published
2023
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2. 1367 A rational approach to selecting CD3-binding antibodies for T-cell engager development

Author

Kate Gibson, Lauren Chong, Tim Jacobs, Patrick Farber, Antonios Samiotakis, Harveer Dhupar, Allison Goodman, Cindy-Lee Crichlow, Melissa Cid, Ping Xiang, Ahn Lee, Irene Yu, Gabrielle Conaghan, Nathalie Blamey, Vivian Li, Valentine de Puyraimond, Patrick Rowe, Stephanie K Masterman, Raffi Tonikian, Bryan C Barnhart, Juntao (Matt) Mai, Philippe Pouliot, Kate Caldwell, Lauren Clifford, Janice Reimer, Karine Herve, John Marwick, Lena M Bolten, Tova Pinsky, Gesa Volkers, Girija Bodhankar, Caitlyn De Jong, Sophie Cullen, Stefan Hannie, Rhys Chappell, Emma Lathouwers, Kirstin Brown, Mark Fogg, and Aaron Yamniuk

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published
2023
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3. An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity

Author

Nina E. Weisser, Mario Sanches, Eric Escobar-Cabrera, Jason O’Toole, Elizabeth Whalen, Peter W. Y. Chan, Grant Wickman, Libin Abraham, Kate Choi, Bryant Harbourne, Antonios Samiotakis, Andrea Hernández Rojas, Gesa Volkers, Jodi Wong, Claire E. Atkinson, Jason Baardsnes, Liam J. Worrall, Duncan Browman, Emma E. Smith, Priya Baichoo, Chi Wing Cheng, Joy Guedia, Sohyeong Kang, Abhishek Mukhopadhyay, Lisa Newhook, Anders Ohrn, Prajwal Raghunatha, Matteo Zago-Schmitt, Joseph D. Schrag, Joel Smith, Patricia Zwierzchowski, Joshua M. Scurll, Vincent Fung, Sonia Black, Natalie C. J. Strynadka, Michael R. Gold, Leonard G. Presta, Gordon Ng, and Surjit Dixit

Subjects
Science
Abstract

The success of HER2-targeted cancer therapy is limited by treatment resistance. Here, the authors engineer an anti-HER2 biparatopic antibody with multiple mechanisms of action including induction of HER2 clustering to trigger complement dependent cytotoxicity, signal inhibition, antibody dependent cellular cytotoxicity and phagocytosis.

Published
2023
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4. Re-use of built environment - Strategic planning of sampling locations for the environmental impact assessment of former airports: The use-case of the former Hellenikon airport in Athens, Greece

Author

Kyriakos C. Lampropoulos, Dimitrios Tamvakis, Antonios Samiotakis, and Antonia Moropoulou

Subjects
Re-use of built environment, Airport, Environmental impact assessment, Electrical resistivity tomography, Engineering (General). Civil engineering (General), TA1-2040, Building construction, TH1-9745
Abstract

The interaction between the built environment and its surrounding ecosystem needs to be taken into account when reuse activities are planned. The bilateral influence of building assets on their surroundings creates a continuity of impacts that exists even when the building stock is replaced; the surrounding environment projects part of the prior impact to the new constructions. A special case of built environment reuse regards the redevelopment of former airports. Such major redevelopment projects require comprehensive environmental impact assessment studies, which necessitate significant resources for the collection of the required documentation and measured data. This work regards a methodology of strategic planning of sampling locations for the assessment of the environmental impact and pollution levels at former airports. It is developed and applied in the use-case of the former Hellenikon airport in Athens, but it can be used to other large-area redevelopment cases.

Published
2022
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