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1. Absence of Granzyme B Positive Tumour-Infiltrating Lymphocytes in Primary Melanoma Excisional Biopsies is Strongly Associated with the Presence of Sentinel Lymph Node Metastasis

Author

I. S. van Houdt, B. J. R. Sluijter, P. A. M. van Leeuwen, L. M. Moesbergen, E. Hooijberg, C. J. L. M. Meijer, T. D. de Gruijl, J. J. Oudejans, and E. Boven

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671
Abstract

Background: Sentinel Lymph Node (SLN) status is strongly related to clinical outcome in melanoma patients. In this study we investigated the possible association between the presence of activated and/or suppressive Tumour Infiltrating Lymphocytes (TILs) and SLN status in clinically stage I/II melanoma patients.

Published
2009
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