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In mobile communication, the most exploratory technology of fifth generation is massive multiple input multiple output (MIMO). The minimum mean square error and zero forcing based linear detectors are used in multiuser detection for MIMO single-carrier frequency division multiple access (SCFDMA). When the received signal is detected and regularization sequence is joined in the equalization of spectral null amplification, these schemes experience an error performance and the signal detection assesses an inversion of a matrix computation that grows into complexity. Ordered successive interference cancelation (OSIC) detection is considered for MIMO SC-FDMA, which uses a posteriori information to eradicate these problems in a realistic environment. To cancel the interference, sorting is preferred based on signal-to-noise ratio and log-likelihood ratio. The distinctiveness of the methodology is to predict the symbol with the lowest error probability. The proposed work is compared with the existing methods, and simulation results prove that the defined algorithm outperforms conventional detection methods and accomplishes better performance with lower complication.