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Vacuum-fried products were prepared with macadamia kernels as raw material. Single factor experiment and response surface Box-Behnken test were used to optimize the vacuum frying process of macadamia kernels. Oil content, acid value, peroxidation value, color difference and sensory quality of vacuum-fried kernel were determined by comparing with raw kernel. The results showed that the effects of freezing temperature, vacuum frying temperature, vacuum frying time and vacuum degree on taste and flavor quality of macadamia kernels were significantly different (P

Macadamia nut polypeptides were prepared by enzymatic hydrolysis of macadamia nut meal, and suitable proteases for the preparation of macadamia antioxidant polypeptides were screened with ABTS+ radical scavenging effects as evaluation indicators. Four constituents (MNAP-1, MNAP-2, MNAP-3, MNAP-4) were obtained by DA201-C macroporous resin and dialysis technology. The scavenging capacity against 1,1-diphenyl-2-picrylhydrazyl radical (DPPH·), hydroxyl radical and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonate radicals) radical (ABTS+·), and reducing power were investigated by comparing with glutathione as controls. The results showed that the suitable protease was complex protease for the preparation of macadamia antioxidant polypeptides, which was better than neutral protease, acid protease, alkaline protease, papain and bromelain at the same concentration. Antioxidant activities of different molecular weight macadamia nut polypeptides were different, which all had strong scavenging capacity against DPPH and ABTS+ radicals, and also had certain scavenging capacity against hydroxyl radical and reducing power. MNAP-4 (molecular weight less than 1000 Da) had the strongest scavenging capacity against DPPH, ABTS+ and hydroxyl radicals and the highest reducing power with half maximal inhibitory concentration (IC50) of 0.36, 6.75, 0.08 and 3.19 mg/mL, respectively, which was lower than other molecular weight polypeptides. Correlation analysis showed different molecular weight macadamia nut polypeptides had good correlations with their DPPH, hydroxyl and ABTS+ radicals scavenging capacity and reducing power with r values of 0.947, 0.964, 0.948 and 0.856 (P

Abstract We hypothesized that the combined use of etomidate and propofol for endoscopic sedation in elderly hypertensive patients could reduce adverse reactions while providing ideal sedation. To validate our hypothesis, we conducted a prospective, randomized, controlled, double‐blinded study. A total of 360 elderly hypertensive patients scheduled for gastroscopy at our hospital were enrolled in the study, of whom 328 completed the trial. The patients were randomly assigned to one of three groups: the propofol group (group P), the etomidate group (group E), or the propofol‐etomidate combination group (mixed at a ratio of 1:1, group PE). We collected and analyzed the cardiopulmonary effects and side effects in each group. Regardless of the sedation drug used, the systolic blood pressure, mean blood pressure, and heart rate of involved patients were significantly affected. Oxygen desaturation and injection pain were more common in group P compared to groups E (33.6% vs. 14.8%, 31.8% vs. 2.7%, both P