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Lumbar plexus block (LPB) is an advanced regional an-esthesia technique practiced by relatively few experi- enced regional anesthesiologists. Difficulties are linked to the depth of structures and the high risk of accidental punctures, lowering its safety expecially in obese or un- favorable patients. Although modern ultrasound guidance may allow visual- ization of the lumbar plexus, ultrasound-guided techniques (i.e., Shamrock and Trident techniques) still require additional expertise while being operator-depend- ent and not suitable in every patient, which represents the most frequent “real world” scenario. Given its usefulness in lower limbs surgery, we struggled to develop a new ultrasound-assisted patient-tailored Traditional Chinese Medicine based operating protocol to increase its safety and constancy of performance and applied it to a trau- matic right femur fracture surgery of a 16-year-old boy.