Search

Your search keyword '"Sanmit Adhikari"' showing total 1 results
Start Over Author "Sanmit Adhikari" Database Directory of Open Access Journals

Refine your results

1 results on '"Sanmit Adhikari"'

1. Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer

Author

Edward M. Kennedy, Agnieszka Denslow, Jacqueline Hewett, Lingxin Kong, Ana De Almeida, Jeffrey D. Bryant, Jennifer S. Lee, Judy Jacques, Sonia Feau, Melissa Hayes, Elizabeth L. McMichael, Daniel Wambua, Terry Farkaly, Amal A Rahmeh, Lauren Herschelman, Danielle Douglas, Jacob Spinale, Sanmit Adhikari, Jessica Deterling, Matt Scott, Brian B. Haines, Mitchell H. Finer, Ted T Ashburn, Christophe Quéva, and Lorena Lerner

Subjects
Science
Abstract

The development of neutralizing antibodies can limit the therapeutic effectiveness of systemically administered oncolytic viruses (OV). Here, to enable repeated intravenous administration, the authors report the development of synthetic RNA viruses formulated within lipid nanoparticles, showing anti-tumor efficacy even in the presence of OV neutralizing antibodies.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results